DK148322C - Analogifremgangsmaade til fremstilling af alfa-mono- eller -difluormethylornithin eller -arginin eller -ornithinalkylestere, deres farmaceutisk acceptable syre- eller basesalte eller optiske isomere - Google Patents
Analogifremgangsmaade til fremstilling af alfa-mono- eller -difluormethylornithin eller -arginin eller -ornithinalkylestere, deres farmaceutisk acceptable syre- eller basesalte eller optiske isomereInfo
- Publication number
- DK148322C DK148322C DK309478A DK309478A DK148322C DK 148322 C DK148322 C DK 148322C DK 309478 A DK309478 A DK 309478A DK 309478 A DK309478 A DK 309478A DK 148322 C DK148322 C DK 148322C
- Authority
- DK
- Denmark
- Prior art keywords
- ornithinal
- coolesters
- difluoromethylornithine
- alfa
- arginine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/20—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/08—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81476577A | 1977-07-11 | 1977-07-11 | |
| US81476577 | 1977-07-11 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK309478A DK309478A (da) | 1979-01-12 |
| DK148322B DK148322B (da) | 1985-06-10 |
| DK148322C true DK148322C (da) | 1985-11-04 |
Family
ID=25215950
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK309478A DK148322C (da) | 1977-07-11 | 1978-07-10 | Analogifremgangsmaade til fremstilling af alfa-mono- eller -difluormethylornithin eller -arginin eller -ornithinalkylestere, deres farmaceutisk acceptable syre- eller basesalte eller optiske isomere |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS63246365A (da) |
| DK (1) | DK148322C (da) |
| ES (4) | ES471596A1 (da) |
| HK (1) | HK76986A (da) |
| IE (1) | IE47081B1 (da) |
| IL (1) | IL54912A (da) |
| IT (1) | IT1105099B (da) |
| NZ (1) | NZ187536A (da) |
| SE (1) | SE444934B (da) |
| ZA (1) | ZA783349B (da) |
-
1978
- 1978-06-06 IE IE1146/78A patent/IE47081B1/en not_active IP Right Cessation
- 1978-06-12 ZA ZA00783349A patent/ZA783349B/xx unknown
- 1978-06-13 NZ NZ187536A patent/NZ187536A/xx unknown
- 1978-06-15 IL IL54912A patent/IL54912A/xx unknown
- 1978-07-10 ES ES471596A patent/ES471596A1/es not_active Expired
- 1978-07-10 SE SE7807691A patent/SE444934B/sv not_active IP Right Cessation
- 1978-07-10 IT IT50231/78A patent/IT1105099B/it active
- 1978-07-10 DK DK309478A patent/DK148322C/da not_active IP Right Cessation
-
1979
- 1979-03-14 ES ES478612A patent/ES478612A1/es not_active Expired
- 1979-03-14 ES ES478610A patent/ES478610A1/es not_active Expired
- 1979-03-14 ES ES478611A patent/ES478611A1/es not_active Expired
-
1986
- 1986-10-09 HK HK769/86A patent/HK76986A/xx not_active IP Right Cessation
-
1987
- 1987-12-28 JP JP62330367A patent/JPS63246365A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| IL54912A (en) | 1984-11-30 |
| SE7807691L (sv) | 1979-01-12 |
| DK309478A (da) | 1979-01-12 |
| IE47081B1 (en) | 1983-12-14 |
| IT7850231A0 (it) | 1978-07-10 |
| JPH0325424B2 (da) | 1991-04-05 |
| ES478611A1 (es) | 1979-07-16 |
| IL54912A0 (en) | 1978-08-31 |
| ES478612A1 (es) | 1979-09-16 |
| ES478610A1 (es) | 1979-07-16 |
| ES471596A1 (es) | 1979-10-01 |
| ZA783349B (en) | 1979-06-27 |
| IE781146L (en) | 1979-01-11 |
| DK148322B (da) | 1985-06-10 |
| IT1105099B (it) | 1985-10-28 |
| JPS63246365A (ja) | 1988-10-13 |
| NZ187536A (en) | 1982-03-23 |
| SE444934B (sv) | 1986-05-20 |
| HK76986A (en) | 1986-10-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK148631C (da) | Analogifremgangsmaade til fremstilling af hydroxykarbonylfosfonsyremonoestere eller fysiologisk acceptable salte og/eller optiske isomerer deraf | |
| DK148711C (da) | Analogifremgangsmaade til fremstilling af 1-(3-mercapto-2-methylpropanoyl)-prolyl-aminosyre-derivater, optiske isomere deraf eller farmaceutisk acceptable salte deraf | |
| DK151884C (da) | Analogifremgangsmaade til fremstilling af 3-(1-imidazolylalkyl)indolderivater eller farmaceutisk acceptable syreadditionssalte deraf | |
| DK151331C (da) | Analogifremgangsmaade til fremstilling af 5-pyridinyl-2(1h)-pyridinon-forbindelser eller farmaceutisk acceptable syreadditionssalte deraf | |
| DK149594C (da) | Analogifremgangsmaade til fremstilling af dipeptidderivater eller syreadditionssalte heraf | |
| DK151623C (da) | Analogifremgangsmaade til fremstilling af n-substituerede moranolinderivater eller farmaceutisk acceptable syreadditionssalte deraf | |
| DK149449C (da) | Analogifremgangsmaade til fremstilling af carbostyrilderivater eller farmaceutisk acceptable salte deraf | |
| DK160300C (da) | Analogifremgangsmaade til fremstilling af substituerede phenoxybenzyloxycarbonylderivater og cyclopropancarboxylsyreestere til anvendelse som udgangsforbindelser herved | |
| DK145260C (da) | Analogifremgangsmaade til fremstilling af 4-acylamino-phenyl-ethanolaminer eller syreadditionssalte heraf | |
| DK148477C (da) | Analogifremgangsmaade til fremstilling af tetrahydropyridinylindolderivater eller additionssalte deraf | |
| DK152114C (da) | Analogifremgangsmaade til fremstilling af propenylaminer eller farmaceutisk acceptable salte deraf | |
| DK149630C (da) | Analogifremgangsmaade til fremstilling af tripeptidamider eller -estere eller fysiologisk acceptable syreadditionssalte deraf | |
| DK157862C (da) | Analogifremgangsmaade til fremstilling af imidazolylphenylamidiner eller farmaceutisk acceptable syreadditionssalte deraf | |
| DK154950C (da) | Analogifremgangsmaade til fremstilling af 1-(benzazolylalkyl)-piperidinderivater eller de farmaceutisk acceptable syreadditionssalte deraf | |
| DK162166C (da) | Analogifremgangsmaade til fremstilling af (2s)-isomere af 2-oe4-(2-hydroxycyclopentan-1-ylmethyl)phenylaapropionsyre eller farmaceutisk acceptable salte deraf | |
| DK149231C (da) | Analogifremgangsmaade til fremstilling af enkephalin-analoge tetrapeptidamider eller syreadditionssalte deraf | |
| DK149269C (da) | Analogifremgangsmaade til fremstilling af beta-mono- eller -difluormethyl-beta-alanin-derivater eller farmaceutisk acceptable salte eller optiske isomere deraf | |
| DK149841C (da) | Analogifremgangsmaade til fremstilling af alfa-fluor-methyl-alfa-aminoalkansyrer eller farmaceutisk acceptable syreadditionssalte deraf | |
| DK151805C (da) | Analogifremgangsmaade til fremstilling af 20,21-di-nor-eburnameninderivater eller farmaceutisk acceptable additionssalte deraf | |
| DK149077C (da) | Analogifremgangsmaade til fremstilling af encephalin-analoge pentapeptidamidderivater eller farmaceutisk acceptable syreadditionssalte deraf | |
| DK144793C (da) | Analogifremgangsmaade til fremstilling af dihydro- eller tetrahydroiminothiaziner eller farmaceutisk acceptable syreadditionssalte deraf | |
| DK154083C (da) | Analogifremgangsmaade til fremstilling af halogenvincamonderivater eller optisk aktive isomere eller syreadditionssalte deraf | |
| DK152427C (da) | Analogifremgangsmaade til fremstilling af 4-thiomethylpyridinforbindelser eller farmaceutisk acceptable syreadditionssalte deraf | |
| DK152211C (da) | Analogifremgangsmaade til fremstilling af n-phenyl-n-(4-piperidinyl)-amider eller farmaceutisk acceptable syreadditionssalte deraf. | |
| DK152208C (da) | Analogifremgangsmaade til fremstilling af 2-phenylamino-phenyleddikesyreamider eller farmaceutisk acceptable salte deraf |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CTFF | Application for supplementary protection certificate (spc) filed |
Free format text: CA 1993 00047, 930630 |
|
| CTFF | Application for supplementary protection certificate (spc) filed |
Free format text: CA 1993 00047, 930630 |
|
| PUP | Patent expired |