DK1499729T3 - Derivater af det NF-kappab-inducerende enzym, fremstilling og anvendelse deraf - Google Patents

Derivater af det NF-kappab-inducerende enzym, fremstilling og anvendelse deraf

Info

Publication number: DK1499729T3
Authority: DK; Denmark
Prior art keywords: kappab; derivatives; preparation; inducing enzyme; inducing
Prior art date: 2002-04-18

Application number

DK03746399.9T

Other languages

English (en)

Other versions

DK1499729T5 (da

Inventor

David Wallach

Parameswaran Ramakrishnan

Taisia Shmushkovich

Original Assignee

Yeda Res & Dev

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-04-18

Filing date

2003-04-15

Publication date

2011-10-03

2002-04-18 Priority claimed from IL14921702A external-priority patent/IL149217A0/xx

2002-10-08 Priority claimed from IL15218302A external-priority patent/IL152183A0/xx

2003-04-15 Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev

2011-10-03 Publication of DK1499729T3 publication Critical patent/DK1499729T3/da

2011-12-05 Application granted granted Critical

2011-12-05 Publication of DK1499729T5 publication Critical patent/DK1499729T5/da

Links

102000004190 Enzymes Human genes 0.000 title 1
108090000790 Enzymes Proteins 0.000 title 1
230000001939 inductive effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
Wood Science & Technology (AREA)
Neurosurgery (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pulmonology (AREA)
Neurology (AREA)
General Engineering & Computer Science (AREA)
Cardiology (AREA)
Cell Biology (AREA)
Toxicology (AREA)
Microbiology (AREA)
Gastroenterology & Hepatology (AREA)
Biotechnology (AREA)
Biophysics (AREA)
Rheumatology (AREA)
Heart & Thoracic Surgery (AREA)
Orthopedic Medicine & Surgery (AREA)
Hospice & Palliative Care (AREA)
Physical Education & Sports Medicine (AREA)
Urology & Nephrology (AREA)

DK03746399.9T 2002-04-18 2003-04-15 Derivater af det NF-kappab-inducerende enzym, fremstilling og anvendelse deraf DK1499729T5 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
IL14921702A IL149217A0 (en)	2002-04-18	2002-04-18	Derivatives of the il-2 receptor gamma chain, their preparation and use
IL15218302A IL152183A0 (en)	2002-10-08	2002-10-08	Derivatives of the il-2 receptor gamma chain, their preparation and use
PCT/IL2003/000317 WO2003087380A1 (en)	2002-04-18	2003-04-15	Derivatives of the nf-kappab inducing enzyme, their preparation and use

Publications (2)

Publication Number	Publication Date
DK1499729T3 true DK1499729T3 (da)	2011-10-03
DK1499729T5 DK1499729T5 (da)	2011-12-05

Family

ID=29252551

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03746399.9T DK1499729T5 (da)	2002-04-18	2003-04-15	Derivater af det NF-kappab-inducerende enzym, fremstilling og anvendelse deraf

Country Status (13)

Country	Link
US (3)	US8330026B2 (da)
EP (2)	EP1499729B9 (da)
JP (2)	JP4435575B2 (da)
AR (2)	AR039645A1 (da)
AT (1)	ATE521707T1 (da)
AU (2)	AU2003222415B2 (da)
CA (2)	CA2482718C (da)
CY (1)	CY1111864T1 (da)
DK (1)	DK1499729T5 (da)
ES (1)	ES2415331T3 (da)
PT (1)	PT1499729E (da)
SI (1)	SI1499729T1 (da)
WO (2)	WO2003087380A1 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL158287A0 (en) *	2003-10-07	2004-05-12	Yeda Res & Dev	Antibodies to nik, their preparation and use
WO2005051423A2 (en) *	2003-11-30	2005-06-09	Yeda Research And Development Co. Ltd	Methods and agents for immune modulation and methods for identifying immune modulators
WO2005087793A2 (en) *	2004-02-05	2005-09-22	The Arizona Board Of Regents, A Body Corporate Acting On Behalf Of Arizona State University	Immunostimulatory compositions and uses thereof
IL166006A0 (en) *	2004-12-27	2006-01-15	Yeda Res & Dev	Pharmaceutical compositions for treating diseases associated with nf-kb activity
US8663309B2 (en)	2007-09-26	2014-03-04	Trivascular, Inc.	Asymmetric stent apparatus and method
US8226701B2 (en)	2007-09-26	2012-07-24	Trivascular, Inc.	Stent and delivery system for deployment thereof
US8066755B2 (en)	2007-09-26	2011-11-29	Trivascular, Inc.	System and method of pivoted stent deployment
AU2008308474B2 (en)	2007-10-04	2014-07-24	Trivascular, Inc.	Modular vascular graft for low profile percutaneous delivery
US8328861B2 (en)	2007-11-16	2012-12-11	Trivascular, Inc.	Delivery system and method for bifurcated graft
US8083789B2 (en)	2007-11-16	2011-12-27	Trivascular, Inc.	Securement assembly and method for expandable endovascular device
US8992595B2 (en)	2012-04-04	2015-03-31	Trivascular, Inc.	Durable stent graft with tapered struts and stable delivery methods and devices
US9498363B2 (en)	2012-04-06	2016-11-22	Trivascular, Inc.	Delivery catheter for endovascular device
US9156897B2 (en) *	2012-06-08	2015-10-13	Alkermes, Inc.	Fusion polypeptides comprising an active protein linked to a mucin-domain polypeptide
WO2018152371A1 (en) *	2017-02-15	2018-08-23	Fred Hutchinson Cancer Research Center	In vivo gene therapy for immune deficiencies
EP3609519B1 (en) *	2017-04-11	2025-11-26	University of Maryland, Baltimore	Compositions and methods for treating inflammation and cancer
WO2022204267A1 (en)	2021-03-24	2022-09-29	Alkermes, Inc.	Upar antibodies and fusion proteins with the same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US510259A (en) *		1893-12-05		Pavement
US5194596A (en) *	1989-07-27	1993-03-16	California Biotechnology Inc.	Production of vascular endothelial cell growth factor
US5350836A (en) *	1989-10-12	1994-09-27	Ohio University	Growth hormone antagonists
JP3255699B2 (ja) *	1992-04-23	2002-02-12	味の素株式会社	ヒトＩＬ−２レセプターγ鎖分子
US7070972B1 (en) *	1995-01-13	2006-07-04	The United States Of America As Represented By The Department Of Health And Human Services	Janus family kinases and identification of immune modulators
UA71889C2 (uk)	1996-04-02	2005-01-17	Йєда Рісерч Енд Дівелопмент Ко. Лтд.	Модулятори зв'язаного з рецептором tnf фактора (traf), їх одержання та застосування
EP1972194A1 (en)	1996-12-03	2008-09-24	Amgen Fremont Inc.	Transgenic mammals having human ig loci including plural vh and vk regions and antibodies produced therefrom
US5843721A (en) *	1997-07-03	1998-12-01	Tularik Inc.	Nucleic acids encoding human NIK protein
NZ514414A (en)	1999-03-04	2004-02-27	Praecis Pharm Inc	Modulators of beta-amyloid peptide aggregation comprising D-amino acids

2003
- 2003-04-15 SI SI200332055T patent/SI1499729T1/sl unknown
- 2003-04-15 ES ES03717504T patent/ES2415331T3/es not_active Expired - Lifetime
- 2003-04-15 CA CA2482718A patent/CA2482718C/en not_active Expired - Fee Related
- 2003-04-15 WO PCT/IL2003/000317 patent/WO2003087380A1/en not_active Ceased
- 2003-04-15 US US10/511,314 patent/US8330026B2/en not_active Expired - Fee Related
- 2003-04-15 JP JP2003584319A patent/JP4435575B2/ja not_active Expired - Fee Related
- 2003-04-15 AU AU2003222415A patent/AU2003222415B2/en not_active Ceased
- 2003-04-15 EP EP03746399A patent/EP1499729B9/en not_active Expired - Lifetime
- 2003-04-15 AT AT03746399T patent/ATE521707T1/de active
- 2003-04-15 US US10/511,722 patent/US7416730B2/en not_active Expired - Fee Related
- 2003-04-15 CA CA2482387A patent/CA2482387C/en not_active Expired - Fee Related
- 2003-04-15 EP EP03717504.9A patent/EP1499724B1/en not_active Expired - Lifetime
- 2003-04-15 PT PT03746399T patent/PT1499729E/pt unknown
- 2003-04-15 DK DK03746399.9T patent/DK1499729T5/da active
- 2003-04-15 JP JP2003584315A patent/JP4435574B2/ja not_active Expired - Fee Related
- 2003-04-15 WO PCT/IL2003/000316 patent/WO2003087374A1/en not_active Ceased
- 2003-04-15 AU AU2003226607A patent/AU2003226607C1/en not_active Ceased
- 2003-04-21 AR ARP030101363A patent/AR039645A1/es not_active Application Discontinuation
- 2003-04-21 AR ARP030101364A patent/AR039646A1/es not_active Application Discontinuation
2008
- 2008-07-01 US US12/166,110 patent/US8048847B2/en not_active Expired - Fee Related
2011
- 2011-09-27 CY CY20111100934T patent/CY1111864T1/el unknown

Also Published As

Publication number	Publication date
AU2003226607A1 (en)	2003-10-27
AR039646A1 (es)	2005-03-02
US8330026B2 (en)	2012-12-11
PT1499729E (pt)	2011-09-06
EP1499724B1 (en)	2013-05-22
WO2003087374A1 (en)	2003-10-23
CA2482387C (en)	2015-03-03
US20090042796A1 (en)	2009-02-12
JP2005530491A (ja)	2005-10-13
AU2003222415B2 (en)	2009-02-05
EP1499729B1 (en)	2011-08-24
AU2003226607C1 (en)	2011-02-24
JP2005525113A (ja)	2005-08-25
US8048847B2 (en)	2011-11-01
CY1111864T1 (el)	2015-11-04
WO2003087374A9 (en)	2005-01-27
US7416730B2 (en)	2008-08-26
ES2415331T3 (es)	2013-07-25
AU2003226607B2 (en)	2009-02-05
SI1499729T1 (sl)	2011-11-30
AU2003222415A1 (en)	2003-10-27
EP1499729B9 (en)	2012-03-14
WO2003087380A1 (en)	2003-10-23
CA2482718C (en)	2014-08-19
CA2482387A1 (en)	2003-10-23
US20050272633A1 (en)	2005-12-08
JP4435574B2 (ja)	2010-03-17
CA2482718A1 (en)	2003-10-23
DK1499729T5 (da)	2011-12-05
JP4435575B2 (ja)	2010-03-17
AR039645A1 (es)	2005-03-02
US20050287144A1 (en)	2005-12-29
EP1499724A1 (en)	2005-01-26
EP1499729A1 (en)	2005-01-26
ATE521707T1 (de)	2011-09-15

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