DK1509523T3 - Triazaspiro-forbindelser anvendelige for at behandle eller forhindre smerte - Google Patents

Triazaspiro-forbindelser anvendelige for at behandle eller forhindre smerte

Info

Publication number
DK1509523T3
DK1509523T3 DK03741857T DK03741857T DK1509523T3 DK 1509523 T3 DK1509523 T3 DK 1509523T3 DK 03741857 T DK03741857 T DK 03741857T DK 03741857 T DK03741857 T DK 03741857T DK 1509523 T3 DK1509523 T3 DK 1509523T3
Authority
DK
Denmark
Prior art keywords
treating
triazaspiro
preventing pain
compounds useful
triazaspiro compounds
Prior art date
Application number
DK03741857T
Other languages
English (en)
Inventor
Zhengming Chen
Sam F Victory
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Application granted granted Critical
Publication of DK1509523T3 publication Critical patent/DK1509523T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
DK03741857T 2002-05-31 2003-06-02 Triazaspiro-forbindelser anvendelige for at behandle eller forhindre smerte DK1509523T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US38480702P 2002-05-31 2002-05-31
US46021903P 2003-04-03 2003-04-03
US10/448,627 US6995168B2 (en) 2002-05-31 2003-05-29 Triazaspiro compounds useful for treating or preventing pain
PCT/US2003/017419 WO2003101953A2 (en) 2002-05-31 2003-06-02 Triazaspiro compounds useful for treating or preventing pain

Publications (1)

Publication Number Publication Date
DK1509523T3 true DK1509523T3 (da) 2009-04-27

Family

ID=29716134

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03741857T DK1509523T3 (da) 2002-05-31 2003-06-02 Triazaspiro-forbindelser anvendelige for at behandle eller forhindre smerte

Country Status (12)

Country Link
US (2) US6995168B2 (da)
EP (1) EP1509523B1 (da)
JP (2) JP4658595B2 (da)
AT (1) ATE421517T1 (da)
AU (1) AU2003273250A1 (da)
CY (1) CY1109031T1 (da)
DE (1) DE60325965D1 (da)
DK (1) DK1509523T3 (da)
ES (1) ES2320750T3 (da)
PT (1) PT1509523E (da)
SI (1) SI1509523T1 (da)
WO (1) WO2003101953A2 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
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US6995168B2 (en) * 2002-05-31 2006-02-07 Euro-Celtique S.A. Triazaspiro compounds useful for treating or preventing pain
EP2256106B1 (en) 2003-07-22 2015-05-06 Astex Therapeutics Limited 3,4-disubstituted 1H-pyrazole compounds and their use as cyclin dependent kinases (CDK) and glycogen synthase kinase-3 (GSK-3) modulators
EP1845973B1 (en) * 2005-01-21 2015-08-12 Astex Therapeutics Limited Pharmaceutical compounds
AR054425A1 (es) 2005-01-21 2007-06-27 Astex Therapeutics Ltd Sales de adicion de piperidin 4-il- amida de acido 4-(2,6-dicloro-benzoilamino) 1h-pirazol-3-carboxilico.
US8404718B2 (en) 2005-01-21 2013-03-26 Astex Therapeutics Limited Combinations of pyrazole kinase inhibitors
DE102005038141A1 (de) * 2005-08-12 2007-02-15 Grünenthal GmbH Substituierte 8-(3-Aminopropyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-on-Derivate
UA107943C2 (xx) * 2009-11-16 2015-03-10 Lilly Co Eli Сполуки спіропіперидину як антагоністи рецептора orl-1
US9963458B2 (en) 2012-12-27 2018-05-08 Purdue Pharma L.P. Indole and indoline-type piperidine compounds and uses thereof
US9951038B2 (en) 2012-12-27 2018-04-24 Purdue Pharma L.P. Quinazolin-4(3H)-one-type piperidine compounds and uses thereof
US10118927B2 (en) 2012-12-27 2018-11-06 Purdue Pharma L.P. Substituted piperidin-4-amino-type compounds and uses thereof
CN103242230B (zh) * 2013-05-02 2015-02-18 陕西步长高新制药有限公司 一种喹啉酮衍生物及其制备方法

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US3155669A (en) * 1962-06-22 1964-11-03 Res Lab Dr C Janssen N V 2, 4, 8-triaza-spiro (4, 5) dec-2-enes
US3161644A (en) 1962-06-22 1964-12-15 Res Lab Dr C Janssen N V 1-benzyl-4-substituted piperidines
US3238216A (en) * 1963-06-20 1966-03-01 Res Lab Dr C Janssen N V Substituted 1, 3, 8-triaza-spiro (4, 5) decanes
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Also Published As

Publication number Publication date
JP2006516239A (ja) 2006-06-29
ES2320750T3 (es) 2009-05-28
EP1509523A2 (en) 2005-03-02
AU2003273250A8 (en) 2003-12-19
PT1509523E (pt) 2009-04-20
US6995168B2 (en) 2006-02-07
JP4658595B2 (ja) 2011-03-23
AU2003273250A1 (en) 2003-12-19
JP2011021021A (ja) 2011-02-03
US7414062B2 (en) 2008-08-19
WO2003101953A2 (en) 2003-12-11
US20050234084A1 (en) 2005-10-20
DE60325965D1 (de) 2009-03-12
EP1509523A4 (en) 2006-04-05
CY1109031T1 (el) 2014-07-02
ATE421517T1 (de) 2009-02-15
EP1509523B1 (en) 2009-01-21
SI1509523T1 (sl) 2009-06-30
WO2003101953A3 (en) 2004-08-05
US20050009854A1 (en) 2005-01-13

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