DK1534672T3 - Retinolderivater, deres anvendelse til behandling af cancer og til potensering af virkningen af andre cytotoksi¬ske midler - Google Patents

Retinolderivater, deres anvendelse til behandling af cancer og til potensering af virkningen af andre cytotoksi¬ske midler

Info

Publication number
DK1534672T3
DK1534672T3 DK02783947.1T DK02783947T DK1534672T3 DK 1534672 T3 DK1534672 T3 DK 1534672T3 DK 02783947 T DK02783947 T DK 02783947T DK 1534672 T3 DK1534672 T3 DK 1534672T3
Authority
DK
Denmark
Prior art keywords
retinold
potenseing
cancer
derivatives
treatment
Prior art date
Application number
DK02783947.1T
Other languages
English (en)
Inventor
Oleg Strelchenok
Julian Aleksov
Original Assignee
Ardenia Investments Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ardenia Investments Ltd filed Critical Ardenia Investments Ltd
Priority claimed from PCT/SE2002/002087 external-priority patent/WO2004009538A1/en
Application granted granted Critical
Publication of DK1534672T3 publication Critical patent/DK1534672T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/17—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing carboxyl groups bound to the carbon skeleton
    • C07C309/18—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing carboxyl groups bound to the carbon skeleton containing amino groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C313/00—Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C313/02—Sulfinic acids; Derivatives thereof
    • C07C313/04—Sulfinic acids; Esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK02783947.1T 2002-07-23 2002-11-15 Retinolderivater, deres anvendelse til behandling af cancer og til potensering af virkningen af andre cytotoksi¬ske midler DK1534672T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39820002P 2002-07-23 2002-07-23
SE0202311A SE0202311D0 (sv) 2002-07-23 2002-07-23 Novel compounds, cytotoxic preparations comprising said compounds, methods of manufacture of said preparations, as well as methods of treatment
PCT/SE2002/002087 WO2004009538A1 (en) 2002-07-23 2002-11-15 Retinol derivatives, their use in the treatment of cancer and for potentiating the efficacy of other cytotoxic agents

Publications (1)

Publication Number Publication Date
DK1534672T3 true DK1534672T3 (da) 2013-07-29

Family

ID=20288630

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02783947.1T DK1534672T3 (da) 2002-07-23 2002-11-15 Retinolderivater, deres anvendelse til behandling af cancer og til potensering af virkningen af andre cytotoksi¬ske midler

Country Status (5)

Country Link
US (1) US7030158B2 (da)
DK (1) DK1534672T3 (da)
ES (1) ES2452540T3 (da)
PT (1) PT1534672E (da)
SE (1) SE0202311D0 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009078754A1 (en) * 2007-12-19 2009-06-25 Ardenia Investments, Ltd. Drug delivery system for administration of poorly water soluble pharmaceutically active substances
WO2009078755A1 (en) 2007-12-19 2009-06-25 Ardenia Investments, Ltd. Drug delivery system for administration of a water soluble, cationic and amphiphilic pharmaceutically active substance
WO2009078756A1 (en) * 2007-12-19 2009-06-25 Ardenia Investments, Ltd. Drug delivery system for administration of a water soluble, cationic and amphiphilic pharmaceutically active substance
JP7009012B2 (ja) * 2015-12-09 2022-01-25 オアスミア ファーマシューティカル アーベー Ｎ－レチノイルシステイン酸アルキルエステルの製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4032187C2 (de) 1990-10-10 1995-03-30 Gradinger F Hermes Pharma N-Retinoyl-L-aminomercapto-Verbindungen und Zwischenprodukte, Verfahren zu ihrer Herstellung und ihre Verwendung
SE0101702D0 (sv) * 2001-05-15 2001-05-15 Ardenia Investments Ltd Novel potentiating compounds

Also Published As

Publication number Publication date
US7030158B2 (en) 2006-04-18
ES2452540T3 (es) 2014-04-01
US20040048923A1 (en) 2004-03-11
PT1534672E (pt) 2013-08-05
SE0202311D0 (sv) 2002-07-23

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