DK153545C - Analogifremgangsmaade til fremstilling af n-substituerede derivater af 3,4,5-trihydroxy-2-hydroxymethyl-piperidin - Google Patents

Analogifremgangsmaade til fremstilling af n-substituerede derivater af 3,4,5-trihydroxy-2-hydroxymethyl-piperidin

Info

Publication number
DK153545C
DK153545C DK084181A DK84181A DK153545C DK 153545 C DK153545 C DK 153545C DK 084181 A DK084181 A DK 084181A DK 84181 A DK84181 A DK 84181A DK 153545 C DK153545 C DK 153545C
Authority
DK
Denmark
Prior art keywords
piperidine
trihydroxy
hydroxymethyl
preparing
substituted derivatives
Prior art date
Application number
DK084181A
Other languages
Danish (da)
English (en)
Other versions
DK84181A (da
DK153545B (da
Inventor
Bodo Junge
Juergen Stoltefuss
Lutz Mueller
Hans-Peter Krause
Ruediger Sitt
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK84181A publication Critical patent/DK84181A/da
Publication of DK153545B publication Critical patent/DK153545B/da
Application granted granted Critical
Publication of DK153545C publication Critical patent/DK153545C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A23K20/132—Heterocyclic compounds containing only one nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Polymers & Plastics (AREA)
  • Endocrinology (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Food Science & Technology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Fodder In General (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Supply Devices, Intensifiers, Converters, And Telemotors (AREA)
  • Rolls And Other Rotary Bodies (AREA)
  • Paints Or Removers (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DK084181A 1980-02-26 1981-02-25 Analogifremgangsmaade til fremstilling af n-substituerede derivater af 3,4,5-trihydroxy-2-hydroxymethyl-piperidin DK153545C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19803007078 DE3007078A1 (de) 1980-02-26 1980-02-26 Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel sowie in der tierernaehrung
DE3007078 1980-02-26

Publications (3)

Publication Number Publication Date
DK84181A DK84181A (da) 1981-08-27
DK153545B DK153545B (da) 1988-07-25
DK153545C true DK153545C (da) 1988-12-05

Family

ID=6095540

Family Applications (1)

Application Number Title Priority Date Filing Date
DK084181A DK153545C (da) 1980-02-26 1981-02-25 Analogifremgangsmaade til fremstilling af n-substituerede derivater af 3,4,5-trihydroxy-2-hydroxymethyl-piperidin

Country Status (18)

Country Link
US (1) US4407809A (th)
EP (1) EP0034784B1 (th)
JP (3) JPS56133267A (th)
AT (1) ATE8623T1 (th)
AU (1) AU538463B2 (th)
CA (1) CA1160634A (th)
DE (2) DE3007078A1 (th)
DK (1) DK153545C (th)
ES (1) ES499782A0 (th)
FI (1) FI75807C (th)
GR (1) GR73691B (th)
HU (1) HU183346B (th)
IE (1) IE51317B1 (th)
IL (1) IL62198A (th)
NO (1) NO155804B (th)
PT (1) PT72507B (th)
SU (1) SU1014471A3 (th)
ZA (1) ZA811252B (th)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3737523A1 (de) * 1987-11-05 1989-05-18 Bayer Ag Verwendung von substituierten hydroxypiperidinen als antivirale mittel
GB8827701D0 (en) * 1987-12-09 1988-12-29 Nippon Shinyaku Co Ltd Thrombolytic &c compositions
US5192772A (en) * 1987-12-09 1993-03-09 Nippon Shinyaku Co. Ltd. Therapeutic agents
US4985445A (en) * 1988-02-12 1991-01-15 Meiji Seika Kaisha, Ltd. Cancer cell metastasis inhibitors and novel compounds
WO1991003242A1 (en) * 1989-09-07 1991-03-21 Nippon Shinyaku Co., Ltd. Antiviral drug
US5536732A (en) * 1990-04-27 1996-07-16 Merrell Pharmaceuticals Inc. N-derivatives of 1-deoxy nojirimycin
US5252587A (en) * 1990-04-27 1993-10-12 Merrell Dow Pharmaceuticals, Inc. N-derivatives of 1-deoxy nojirimycin
US5258518A (en) * 1992-04-01 1993-11-02 G. D. Searle & Co. 2-substituted tertiary carbinol derivatives of deoxynojirimycin
US6177447B1 (en) * 1996-07-15 2001-01-23 Universiteit Van Amsterdam Deoxynojirimycin derivatives and their uses as glucosylceramidase inhibitors
GB0100889D0 (en) 2001-01-12 2001-02-21 Oxford Glycosciences Uk Ltd Compounds
AU2003248960B2 (en) 2002-07-17 2009-06-25 Idorsia Pharmaceuticals Ltd Piperidinetriol derivatives as inhibitors of glycosylceramidsynthase
ES2393331T3 (es) * 2002-07-17 2012-12-20 Actelion Pharmaceuticals Ltd. Derivados de piperidintriol como inhibidores de la glucosiliceramida sintasa
GB0313678D0 (en) * 2003-06-13 2003-07-16 Oxford Glycosciences Uk Ltd Novel compounds
GB0313677D0 (en) * 2003-06-13 2003-07-16 Oxford Glycosciences Uk Ltd Novel compound
CN101489554A (zh) * 2006-05-24 2009-07-22 联合治疗公司 脱氧吉瑞霉素和d-阿拉伯胶素醇类似物及使用方法
WO2010027996A1 (en) * 2008-09-02 2010-03-11 Institute For Hepatitis And Virus Research Novel imino sugar derivatives demonstrate potent antiviral activity and reduced toxicity
CA2875975A1 (en) * 2012-06-06 2013-12-12 Unither Virology, Llc Novel iminosugars and their applications
CA2924026C (en) * 2013-09-16 2021-12-28 Emergent Virology Llc Deoxynojirimycin derivatives and methods of their using

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1555654A (en) * 1977-06-25 1979-11-14 Exxon Research Engineering Co Agricultural burner apparatus
NO154918C (no) * 1977-08-27 1987-01-14 Bayer Ag Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
GB2020278B (en) * 1978-05-03 1983-02-23 Nippon Shinyaku Co Ltd Moranoline dervitives
DE2839309A1 (de) * 1978-09-09 1980-03-27 Bayer Ag 3,4,5-trihydroxypiperidin-derivate
JPS5683409A (en) * 1979-12-13 1981-07-08 Nippon Shinyaku Co Ltd Plant growth regulator
DE3322006A1 (de) * 1983-06-18 1984-12-20 Robert Bosch Gmbh, 7000 Stuttgart Vorrichtung zur steuerung eines induktiven stellgliedes, insbesondere eines vergasers

Also Published As

Publication number Publication date
DK84181A (da) 1981-08-27
SU1014471A3 (ru) 1983-04-23
DE3007078A1 (de) 1981-09-10
ES8201549A1 (es) 1981-12-16
IL62198A0 (en) 1981-03-31
JPS56133267A (en) 1981-10-19
CA1160634A (en) 1984-01-17
JPS6152147B2 (th) 1986-11-12
AU538463B2 (en) 1984-08-16
EP0034784B1 (de) 1984-07-25
DE3164944D1 (en) 1984-08-30
IE51317B1 (en) 1986-12-10
ZA811252B (en) 1982-03-31
JPS60166616A (ja) 1985-08-29
JPH0342243B2 (th) 1991-06-26
PT72507B (en) 1982-02-05
NO810485L (no) 1981-08-27
EP0034784A1 (de) 1981-09-02
IL62198A (en) 1985-03-31
FI75807B (fi) 1988-04-29
NO155804B (no) 1987-02-23
DK153545B (da) 1988-07-25
GR73691B (th) 1984-04-03
FI810559L (fi) 1981-08-27
AU6748081A (en) 1981-09-03
FI75807C (fi) 1988-08-08
IE810391L (en) 1981-08-26
HU183346B (en) 1984-04-28
US4407809A (en) 1983-10-04
ES499782A0 (es) 1981-12-16
ATE8623T1 (de) 1984-08-15
JPS60166663A (ja) 1985-08-29
PT72507A (en) 1981-03-01

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Legal Events

Date Code Title Description
PBP Patent lapsed