DK1562559T3 - Bionedbrydelige kolloide partikler, især til pulmonale applikationer - Google Patents

Bionedbrydelige kolloide partikler, især til pulmonale applikationer

Info

Publication number
DK1562559T3
DK1562559T3 DK03785518.6T DK03785518T DK1562559T3 DK 1562559 T3 DK1562559 T3 DK 1562559T3 DK 03785518 T DK03785518 T DK 03785518T DK 1562559 T3 DK1562559 T3 DK 1562559T3
Authority
DK
Denmark
Prior art keywords
pulmonal
applications
colloid particles
biodegradable
biodegradable colloid
Prior art date
Application number
DK03785518.6T
Other languages
English (en)
Inventor
Lea Ann Dailey
Werner Seeger
Thomas Schmehl
Tobias Gessler
Matthias Wittmar
Original Assignee
Univ Giessen Justus Liebig
Univ Marburg Philipps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Giessen Justus Liebig, Univ Marburg Philipps filed Critical Univ Giessen Justus Liebig
Application granted granted Critical
Publication of DK1562559T3 publication Critical patent/DK1562559T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • C08F283/06—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polyethers, polyoxymethylenes or polyacetals
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/44—Preparation of metal salts or ammonium salts
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L51/00—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C08L51/08—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers grafted on to macromolecular compounds obtained otherwise than by reactions only involving unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Colloid Chemistry (AREA)
DK03785518.6T 2002-11-15 2003-11-14 Bionedbrydelige kolloide partikler, især til pulmonale applikationer DK1562559T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10253623A DE10253623B4 (de) 2002-11-15 2002-11-15 Bioabbaubare kolloidale Partikel, insbesondere für pulmonale Applikationen
PCT/DE2003/003787 WO2004046202A2 (de) 2002-11-15 2003-11-14 Bioabbaubare kolloidale partikel, insbesondere für pulmonale applikationen

Publications (1)

Publication Number Publication Date
DK1562559T3 true DK1562559T3 (da) 2012-09-24

Family

ID=32240119

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03785518.6T DK1562559T3 (da) 2002-11-15 2003-11-14 Bionedbrydelige kolloide partikler, især til pulmonale applikationer

Country Status (9)

Country Link
US (1) US20060127485A1 (da)
EP (1) EP1562559B1 (da)
AU (1) AU2003294626A1 (da)
CA (1) CA2545877C (da)
DE (1) DE10253623B4 (da)
DK (1) DK1562559T3 (da)
ES (1) ES2389471T3 (da)
PT (1) PT1562559E (da)
WO (1) WO2004046202A2 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007000979A (es) * 2004-07-26 2007-07-11 Cotherix Inc Tratamiento de la hipertension pulmonar por iloprost inhalado con una formulacion microparticulada.
EP2407150A1 (de) * 2010-07-16 2012-01-18 Justus-Liebig-Universität Gießen Nano- und Mikropolymerpartikel zur Aufrechterhaltung einer niedrigen Oberflächenspannung in der Lunge und zum Schutz des pulmonalen Surfactants
EP2526927A1 (de) * 2011-05-25 2012-11-28 Justus-Liebig-Universität Gießen Biokompatible Nano- und Mikropartikel beschichtet mit Stabilisatoren für die pulmonale Applikation
EP2526926A1 (de) * 2011-05-25 2012-11-28 Justus-Liebig-Universität Gießen Biokompatible Nanopolymerpartikel mit Wirkstoffen für die pulmonale Applikation
DE102012003730A1 (de) 2012-02-28 2013-08-29 Nanohale Ag Verfahren zur herstellung eines kammpolymers
CN107903348B (zh) * 2017-11-28 2020-06-26 常州大学 一种聚乙二醇接枝聚甲基丙烯酸甲酯两亲性接枝共聚物的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3427797A1 (de) * 1984-07-25 1986-02-06 Schering AG, 1000 Berlin und 4709 Bergkamen Zytoprotektive wirkung von prostacyclin-derivaten an leber, bauchspeicheldruese und niere
DE19839515B4 (de) * 1998-08-29 2012-02-02 Nanohale Gmbh Neue pharmazeutische Zubereitung, enthaltend kolloidale Polymer-Wirkstoff-Assoziate, insbesondere auch für mucosale Wirkstoffverabreichung
ES2345182T3 (es) * 2000-03-08 2010-09-17 Nanohale Gmbh Vehiculos nanoparticulados coloidales que contienen polimeros en peine solubles en agua cargados o sin cargar y su uso para administracion mucosa.
US6616944B2 (en) * 2000-03-08 2003-09-09 Medinnova Gesellschaft Fur Medizinsche Innovationen Aus Adkademischer Forschung Mbh Self-assembling colloidal carriers for protein delivery
DE10104991A1 (de) * 2001-02-03 2002-08-08 Clariant Gmbh Mikroverkapselte biologisch aktive Wirkstoffe enthaltend ein wasserlösliches oder wasserdispergierbares Kammpolymer
AU2002334939A1 (en) * 2001-10-12 2003-04-22 Eugene R. Cooper Compositions having a combination of particles for immediate release and for controlled release

Also Published As

Publication number Publication date
ES2389471T3 (es) 2012-10-26
PT1562559E (pt) 2012-09-20
WO2004046202A3 (de) 2004-12-16
DE10253623B4 (de) 2006-03-09
DE10253623A1 (de) 2004-06-03
EP1562559B1 (de) 2012-06-20
AU2003294626A8 (en) 2004-06-15
CA2545877A1 (en) 2004-06-03
US20060127485A1 (en) 2006-06-15
AU2003294626A1 (en) 2004-06-15
WO2004046202A2 (de) 2004-06-03
EP1562559A2 (de) 2005-08-17
CA2545877C (en) 2013-03-12

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