DK1567653T3 - Recombinant koppevirus, som omfatter i det mindste to kokoppe ATI promoterer - Google Patents
Recombinant koppevirus, som omfatter i det mindste to kokoppe ATI promotererInfo
- Publication number
- DK1567653T3 DK1567653T3 DK03789029T DK03789029T DK1567653T3 DK 1567653 T3 DK1567653 T3 DK 1567653T3 DK 03789029 T DK03789029 T DK 03789029T DK 03789029 T DK03789029 T DK 03789029T DK 1567653 T3 DK1567653 T3 DK 1567653T3
- Authority
- DK
- Denmark
- Prior art keywords
- coconut
- seq
- ati
- smallpox virus
- recombinant
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/863—Poxviral vectors, e.g. entomopoxvirus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/275—Poxviridae, e.g. avipoxvirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/60—Vector systems having a special element relevant for transcription from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Virology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- AIDS & HIV (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200201814 | 2002-11-25 | ||
| PCT/EP2003/012610 WO2004048582A2 (en) | 2002-11-25 | 2003-11-12 | Recombinant poxvirus comprising at least two cowpox ati promoters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1567653T3 true DK1567653T3 (da) | 2007-10-15 |
Family
ID=32337938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03789029T DK1567653T3 (da) | 2002-11-25 | 2003-11-12 | Recombinant koppevirus, som omfatter i det mindste to kokoppe ATI promoterer |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US7300658B2 (da) |
| EP (1) | EP1567653B1 (da) |
| JP (1) | JP2006515170A (da) |
| KR (1) | KR20050083839A (da) |
| CN (1) | CN1717488A (da) |
| AT (1) | ATE365220T1 (da) |
| AU (1) | AU2003293675B2 (da) |
| CA (1) | CA2501168A1 (da) |
| CY (1) | CY1106883T1 (da) |
| DE (1) | DE60314541T2 (da) |
| DK (1) | DK1567653T3 (da) |
| EA (1) | EA012723B1 (da) |
| ES (1) | ES2288634T3 (da) |
| IL (1) | IL167844A (da) |
| MX (1) | MXPA05005549A (da) |
| NO (1) | NO20053125D0 (da) |
| NZ (1) | NZ540156A (da) |
| PL (1) | PL375740A1 (da) |
| PT (1) | PT1567653E (da) |
| UA (1) | UA85379C2 (da) |
| WO (1) | WO2004048582A2 (da) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101676389A (zh) * | 2000-11-23 | 2010-03-24 | 巴法里安诺迪克有限公司 | 改良安卡拉痘苗病毒变体 |
| PL218318B1 (pl) * | 2002-05-16 | 2014-11-28 | Bavarian Nordic As | Rekombinowany wirus krowianki Ankara (MVA), zawierająca go komórka, szczepionka lub kompozycja farmaceutyczna, sposób lub zestaw do jego otrzymywania, sekwencja DNA zawierająca genom tego wirusa oraz sposób wykrywania tego wirusa lub komórek nim zainfekowanych |
| US7501127B2 (en) | 2002-05-16 | 2009-03-10 | Bavarian Nordic A/S | Intergenic regions as novel sites for insertion of HIV DNA sequences in the genome of Modified Vaccinia virus Ankara |
| WO2008100292A2 (en) | 2006-10-16 | 2008-08-21 | Genelux Corporation | Modified vaccinia virus strains for use in diagnostic and therapeutic methods |
| US20110052627A1 (en) * | 2008-06-20 | 2011-03-03 | Paul Chaplin | Recombinant modified vaccinia virus measles vaccine |
| WO2010057650A1 (en) * | 2008-11-21 | 2010-05-27 | Bavarian Nordic A/S | Vector comprising multiple homologous nucleotide sequences |
| US8394385B2 (en) * | 2009-03-13 | 2013-03-12 | Bavarian Nordic A/S | Optimized early-late promoter combined with repeated vaccination favors cytotoxic T cell response against recombinant antigen in MVA vaccines |
| WO2013115884A2 (en) * | 2011-11-15 | 2013-08-08 | Trustees Of Boston University | Pyridopyrimidinone inhibitors of viruses |
| US11701418B2 (en) | 2015-01-12 | 2023-07-18 | Geovax, Inc. | Replication-deficient modified vaccinia Ankara (MVA) expressing Ebola virus glycoprotein (GP) and matrix protein (VP40) |
| KR20160140075A (ko) | 2015-05-29 | 2016-12-07 | 코오롱생명과학 주식회사 | 폭스바이러스 유래 프로모터 및 이를 포함하는 벡터 |
| FR3042121A1 (fr) | 2015-10-08 | 2017-04-14 | Jean-Marc Limacher | Composition anti-tumorale |
| BR112018010639A2 (pt) * | 2015-11-24 | 2019-01-22 | Glaxosmithkline Ip Dev Ltd | método de transfecção transitória para produção retroviral. |
| EP3380604B1 (en) * | 2015-11-24 | 2022-12-28 | GlaxoSmithKline Intellectual Property Development Limited | Stable cell lines for retroviral production |
| CA3011014A1 (en) | 2016-01-08 | 2017-07-13 | Geovax, Inc. | Compositions and methods for generating an immune response to a tumor associated antigen |
| WO2017136419A1 (en) | 2016-02-03 | 2017-08-10 | Geovax Inc. | Compositions and methods for generating an immune response to a flavivirus |
| WO2018031694A1 (en) * | 2016-08-09 | 2018-02-15 | City Of Hope | Chimeric poxvirus compositions and uses thereof |
| US11311612B2 (en) | 2017-09-19 | 2022-04-26 | Geovax, Inc. | Compositions and methods for generating an immune response to treat or prevent malaria |
| IL295482A (en) | 2020-02-14 | 2022-10-01 | Geovax Inc | Vaccines and their uses to induce an immune response to sars-cov2 |
| FR3160186A1 (fr) | 2024-03-13 | 2025-09-19 | Odimma Therapeutics | Vecteur non-viral pour transcription augmentee |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5443964A (en) * | 1987-08-10 | 1995-08-22 | Duke University | Poxvirus insertion/expression vector |
| US5759841A (en) * | 1990-11-20 | 1998-06-02 | Virogenetics Corporation | Immunological composition of measles virus utilizing recombinant poxvirus |
| UA68327C2 (en) * | 1995-07-04 | 2004-08-16 | Gsf Forschungszentrum Fur Unwe | A recombinant mva virus, an isolated eukaryotic cell, infected with recombinant mva virus, a method for production in vitro of polypeptides with use of said cell, a method for production in vitro of virus parts (variants), vaccine containing the recombinant mva virus, a method for immunization of animals |
| EP0951555A2 (en) * | 1996-09-24 | 1999-10-27 | Bavarian Nordic Research Institute A/S | Recombinant mva virus expressing dengue virus antigens, and the use thereof in vaccines |
| DE60040662D1 (de) * | 1999-05-28 | 2008-12-11 | Helmholtz Zentrum Muenchen | Vektor zur integration von heterologen sequenzen in poxvirusgenomen |
| CN1250731C (zh) * | 2000-08-29 | 2006-04-12 | 惠氏控股公司 | 正链rna病毒复制子颗粒的包装 |
-
2003
- 2003-11-12 AU AU2003293675A patent/AU2003293675B2/en not_active Ceased
- 2003-11-12 DK DK03789029T patent/DK1567653T3/da active
- 2003-11-12 EP EP03789029A patent/EP1567653B1/en not_active Expired - Lifetime
- 2003-11-12 KR KR1020057007295A patent/KR20050083839A/ko not_active Abandoned
- 2003-11-12 PT PT03789029T patent/PT1567653E/pt unknown
- 2003-11-12 JP JP2004554335A patent/JP2006515170A/ja active Pending
- 2003-11-12 DE DE60314541T patent/DE60314541T2/de not_active Expired - Lifetime
- 2003-11-12 WO PCT/EP2003/012610 patent/WO2004048582A2/en not_active Ceased
- 2003-11-12 CA CA002501168A patent/CA2501168A1/en not_active Abandoned
- 2003-11-12 AT AT03789029T patent/ATE365220T1/de active
- 2003-11-12 PL PL03375740A patent/PL375740A1/xx not_active Application Discontinuation
- 2003-11-12 NZ NZ540156A patent/NZ540156A/en not_active IP Right Cessation
- 2003-11-12 US US10/535,371 patent/US7300658B2/en not_active Expired - Fee Related
- 2003-11-12 EA EA200500879A patent/EA012723B1/ru not_active IP Right Cessation
- 2003-11-12 CN CNA2003801040985A patent/CN1717488A/zh active Pending
- 2003-11-12 ES ES03789029T patent/ES2288634T3/es not_active Expired - Lifetime
- 2003-11-12 MX MXPA05005549A patent/MXPA05005549A/es active IP Right Grant
- 2003-11-12 UA UAA200506292A patent/UA85379C2/ru unknown
-
2005
- 2005-04-04 IL IL167844A patent/IL167844A/en not_active IP Right Cessation
- 2005-06-24 NO NO20053125A patent/NO20053125D0/no not_active Application Discontinuation
-
2007
- 2007-09-20 CY CY20071101220T patent/CY1106883T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2501168A1 (en) | 2004-06-10 |
| AU2003293675A1 (en) | 2004-06-18 |
| US20060153874A1 (en) | 2006-07-13 |
| DE60314541T2 (de) | 2008-02-28 |
| IL167844A (en) | 2011-03-31 |
| PL375740A1 (en) | 2005-12-12 |
| EA200500879A1 (ru) | 2005-10-27 |
| CN1717488A (zh) | 2006-01-04 |
| MXPA05005549A (es) | 2005-08-16 |
| WO2004048582A3 (en) | 2004-08-12 |
| EP1567653B1 (en) | 2007-06-20 |
| NO20053125L (no) | 2005-06-24 |
| PT1567653E (pt) | 2007-10-01 |
| CY1106883T1 (el) | 2012-09-26 |
| KR20050083839A (ko) | 2005-08-26 |
| ATE365220T1 (de) | 2007-07-15 |
| NZ540156A (en) | 2006-11-30 |
| DE60314541D1 (de) | 2007-08-02 |
| UA85379C2 (ru) | 2009-01-26 |
| NO20053125D0 (no) | 2005-06-24 |
| US7300658B2 (en) | 2007-11-27 |
| ES2288634T3 (es) | 2008-01-16 |
| EP1567653A2 (en) | 2005-08-31 |
| JP2006515170A (ja) | 2006-05-25 |
| EA012723B1 (ru) | 2009-12-30 |
| WO2004048582A2 (en) | 2004-06-10 |
| AU2003293675B2 (en) | 2009-04-23 |
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