DK156957C - Analogifremgangsmaade til fremstilling af crf eller crf-analoge peptidforbindelser og peptidmellemprodukter til gennemfoerelse af fremgangsmaaden - Google Patents

Analogifremgangsmaade til fremstilling af crf eller crf-analoge peptidforbindelser og peptidmellemprodukter til gennemfoerelse af fremgangsmaaden

Info

Publication number: DK156957C
Authority: DK; Denmark
Prior art keywords: glu; gln; leu; ala; lys
Prior art date: 1981-06-08

Application number

DK254982A

Other languages

Danish (da)

English (en)

Other versions

DK254982A (da

DK156957B (da

Inventor

Jr Wylie Walker Vale

Joachim Spiess

Catherine Laure Rivier

Jean Edouard Frederick Rivier

Original Assignee

Salk Inst For Biological Studi

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-06-08

Filing date

1982-06-07

Publication date

1990-03-19

1982-06-07 Application filed by Salk Inst For Biological Studi filed Critical Salk Inst For Biological Studi

1982-12-09 Publication of DK254982A publication Critical patent/DK254982A/da

1989-10-23 Publication of DK156957B publication Critical patent/DK156957B/da

1990-03-19 Application granted granted Critical

1990-03-19 Publication of DK156957C publication Critical patent/DK156957C/da

Links

238000000034 method Methods 0.000 title abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 8
229910052739 hydrogen Inorganic materials 0.000 abstract 8
239000001257 hydrogen Substances 0.000 abstract 8
125000006239 protecting group Chemical group 0.000 abstract 7
108090000765 processed proteins & peptides Proteins 0.000 abstract 4
HLPLTUJPJMFPMP-BYPYZUCNSA-N pyroglutamylglycine Chemical group OC(=O)CNC(=O)[C@@H]1CCC(=O)N1 HLPLTUJPJMFPMP-BYPYZUCNSA-N 0.000 abstract 4
108010041049 pyroglutamylglycine Chemical group 0.000 abstract 4
229920001184 polypeptide Polymers 0.000 abstract 3
102000004196 processed proteins & peptides Human genes 0.000 abstract 3
-1 Ala Chemical compound 0.000 abstract 2
OWOFCNWTMWOOJJ-WDSKDSINSA-N Gln-Glu Chemical group NC(=O)CC[C@H](N)C(=O)N[C@@H](CCC(O)=O)C(O)=O OWOFCNWTMWOOJJ-WDSKDSINSA-N 0.000 abstract 2
WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical group OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 2
QEFRNWWLZKMPFJ-YGVKFDHGSA-N L-methionine S-oxide Chemical compound CS(=O)CC[C@H](N)C(O)=O QEFRNWWLZKMPFJ-YGVKFDHGSA-N 0.000 abstract 2
ZOHGLPQGEHSLPD-FXQIFTODSA-N Ser-Gln-Glu Chemical group [H]N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O ZOHGLPQGEHSLPD-FXQIFTODSA-N 0.000 abstract 2
231100000252 nontoxic Toxicity 0.000 abstract 2
230000003000 nontoxic effect Effects 0.000 abstract 2
229920005990 polystyrene resin Polymers 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
125000002252 acyl group Chemical group 0.000 abstract 1
230000001476 alcoholic effect Effects 0.000 abstract 1
125000003368 amide group Chemical group 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
125000003277 amino group Chemical group 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
125000002795 guanidino group Chemical group C(N)(=N)N* 0.000 abstract 1
229940042795 hydrazides for tuberculosis treatment Drugs 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
229920005989 resin Polymers 0.000 abstract 1
239000011347 resin Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57509—Corticotropin releasing factor [CRF] (Urotensin)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Endocrinology (AREA)
Biophysics (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmacology & Pharmacy (AREA)
Molecular Biology (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Analytical Chemistry (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Train Traffic Observation, Control, And Security (AREA)
Developing Agents For Electrophotography (AREA)
Polyesters Or Polycarbonates (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Heat Sensitive Colour Forming Recording (AREA)
Electrotherapy Devices (AREA)
Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Vehicle Body Suspensions (AREA)
Control Of Eletrric Generators (AREA)

DK254982A 1981-06-08 1982-06-07 Analogifremgangsmaade til fremstilling af crf eller crf-analoge peptidforbindelser og peptidmellemprodukter til gennemfoerelse af fremgangsmaaden DK156957C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US27162481A	1981-06-08	1981-06-08
US27162481		1981-06-08

Publications (3)

Publication Number	Publication Date
DK254982A DK254982A (da)	1982-12-09
DK156957B DK156957B (da)	1989-10-23
DK156957C true DK156957C (da)	1990-03-19

Family

ID=23036364

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK254982A DK156957C (da)	1981-06-08	1982-06-07	Analogifremgangsmaade til fremstilling af crf eller crf-analoge peptidforbindelser og peptidmellemprodukter til gennemfoerelse af fremgangsmaaden

Country Status (15)

Country	Link
EP (1)	EP0067608B1 (cs)
JP (1)	JPS57212149A (cs)
KR (1)	KR890002774B1 (cs)
AT (1)	ATE6505T1 (cs)
AU (1)	AU554676B2 (cs)
CA (1)	CA1243301A (cs)
DE (1)	DE3260057D1 (cs)
DK (1)	DK156957C (cs)
ES (1)	ES512892A0 (cs)
GR (1)	GR75679B (cs)
IE (1)	IE53488B1 (cs)
IL (1)	IL65937A (cs)
NZ (1)	NZ200711A (cs)
PH (1)	PH20364A (cs)
ZA (1)	ZA823635B (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE88481T1 (de) *	1984-02-23	1993-05-15	Salk Inst For Biological Studi	Crf-analoga.
CA1341051C (en) *	1988-09-23	2000-07-11	Jean Edouard Frederic Rivier	Crf antagonists
ZA898329B (en) *	1988-11-14	1990-07-25	Salk Inst For Biological Studi	Fish crf
US5235036A (en) *	1991-05-31	1993-08-10	The Salk Institute For Biological Studies	Crf analogs
DE4110422A1 (de) *	1991-03-29	1992-10-01	Bissendorf Peptide Gmbh	Arzneimittel enthaltend humanes corticotropin-releasing hormon (crh) und/oder dessen derivate und/oder glucocorticoide natuerlicher und/oder synthetischer provenienz
US6039956A (en) *	1994-09-12	2000-03-21	Pennsylvania, Trustees Of The University Of, The	Corticotropin release inhibiting factor and methods of using same for treating behavioral symptoms in an anxiety disorder
US5830866A (en) *	1994-09-12	1998-11-03	The Trustees Of The University Of Pennsylvania	Corticotropin release inhibiting factor and methods of using same
KR102259056B1 (ko)	2017-12-29	2021-06-01	(주)에스엠테크	디아민 화합물과 알루미네이트계 화합물을 포함하는 광물 미분쇄용 분쇄조제 조성물 및 이를 사용한 광물의 미분쇄방법
KR20200121309A (ko)	2018-02-16	2020-10-23	제이엔씨 주식회사	중합성 화합물, 중합성 조성물, 중합체 및 포토레지스트용 조성물

1982
- 1982-01-04 GR GR68352A patent/GR75679B/el not_active IP Right Cessation
- 1982-05-24 NZ NZ200711A patent/NZ200711A/en unknown
- 1982-05-25 ZA ZA823635A patent/ZA823635B/xx unknown
- 1982-05-26 PH PH27349A patent/PH20364A/en unknown
- 1982-06-01 EP EP82302812A patent/EP0067608B1/en not_active Expired
- 1982-06-01 IL IL65937A patent/IL65937A/xx not_active IP Right Cessation
- 1982-06-01 AT AT82302812T patent/ATE6505T1/de not_active IP Right Cessation
- 1982-06-01 DE DE8282302812T patent/DE3260057D1/de not_active Expired
- 1982-06-01 CA CA000404182A patent/CA1243301A/en not_active Expired
- 1982-06-02 IE IE1330/82A patent/IE53488B1/en unknown
- 1982-06-03 AU AU84455/82A patent/AU554676B2/en not_active Ceased
- 1982-06-07 DK DK254982A patent/DK156957C/da not_active IP Right Cessation
- 1982-06-07 KR KR8202541A patent/KR890002774B1/ko not_active Expired
- 1982-06-07 ES ES512892A patent/ES512892A0/es active Granted
- 1982-06-08 JP JP57098388A patent/JPS57212149A/ja active Granted

Also Published As

Publication number	Publication date
PH20364A (en)	1986-12-04
IE53488B1 (en)	1988-11-23
AU554676B2 (en)	1986-08-28
JPS57212149A (en)	1982-12-27
ES8401446A1 (es)	1983-12-01
CA1243301A (en)	1988-10-18
GR75679B (cs)	1984-08-02
EP0067608A1 (en)	1982-12-22
AU8445582A (en)	1982-12-16
IE821330L (en)	1982-12-08
JPS642600B2 (cs)	1989-01-18
DK254982A (da)	1982-12-09
ES512892A0 (es)	1983-12-01
DK156957B (da)	1989-10-23
ATE6505T1 (de)	1984-03-15
IL65937A (en)	1986-09-30
DE3260057D1 (en)	1984-04-12
EP0067608B1 (en)	1984-03-07
KR840000477A (ko)	1984-02-22
IL65937A0 (en)	1982-09-30
ZA823635B (en)	1983-03-30
NZ200711A (en)	1986-02-21
KR890002774B1 (ko)	1989-07-28

Legal Events

Date	Code	Title	Description
2002-01-28	PBP	Patent lapsed

Publication	Publication Date	Title
DE3875538D1 (de)	1992-12-03	Aminoluciferine, verfahren zu deren herstellung und ihre verwendung.
KR840005080A (ko)	1984-11-03	디노르핀 아미드 동족체의 제조방법
ES8802129A1 (es)	1988-04-01	Procedimiento para preparar un analogo polipeptido inhibidorde resina
DK254982A (da)	1982-12-09	Fremgangsmaade til fremstilling af en peptidforbindelse og peptidmellemprodukt til gennemfoerelse af fremgangsmaaden
KR930701481A (ko)	1993-06-11	리포폴리사카라이드에 대해 친화성을 갖는 신규 폴리펩티드 및 그의 용도
DK0437556T3 (da)	1996-12-30	Substitutionsanaloger af magaininpeptider
ATE53220T1 (de)	1990-06-15	Polypeptide.
KR900009699A (ko)	1990-07-05	항응고성 펩타이드 및 이의 제조방법
ATE30919T1 (de)	1987-12-15	Magensekretion hemmende peptidderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel.
US4111924A (en)	1978-09-05	Method for removal of thiol-protecting groups
IL61922A0 (en)	1981-02-27	Angiotensin-ii analogues containing an -hydroxycarboxylic acid residue in position 8,and process for the preparation thereof
CA2193384A1 (en)	1996-02-08	Use of gabapentin in the treatment of anxiety and panic
GB992957A (en)	1965-05-26	New decapeptides and their manufacture
US4389342A (en)	1983-06-21	Synthetic hormone-like peptides and method for their synthesis
US4242238A (en)	1980-12-30	Synthesis of peptides
DE3882233D1 (de)	1993-08-12	Gefaessaktive peptide.
EP0147175A3 (en)	1987-02-25	Novel basic polypeptides and a method of producing thereof
KR850000980A (ko)	1985-03-14	인슐린 유도체의 제조방법
RU95113473A (ru)	1997-10-20	Аналоги инсулина способ его получения, фармацевтическая композиция на его основе
Joubert	1981	Primary structure and properties of toxin CM-1b from Naja naja kaouthia (Siamese cobra) venom
RU93005177A (ru)	1995-07-20	Аналоги апротинина, днк, вектор, клетка, способ получения аналогов, фармацевтическая композиция, применение аналогов
KR870007207A (ko)	1987-08-17	소마토스타틴 유도체의 제조방법
GB1046303A (en)	1966-10-19	Polypeptides
KR830007080A (ko)	1983-10-14	무식욕유발성 펩티드류의 제조방법
SE8006333L (sv)	1981-03-12	Polypeptid psp och salter derav