DK1572622T3 - Anvendelse af levalbuterol-L-tartrat ved fremstilling af en doseringsinhalator - Google Patents

Anvendelse af levalbuterol-L-tartrat ved fremstilling af en doseringsinhalator

Info

Publication number: DK1572622T3
Authority: DK; Denmark
Prior art keywords: levalbuterol; tartrate; preparation; dosage inhaler; inhaler
Prior art date: 2002-12-10

Application number

DK03786896T

Other languages

Danish (da)

English (en)

Inventor

Roger Bakale

Paul Mcglynn

Craig Sturge

Original Assignee

Sepracor Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-10

Filing date

2003-12-08

Publication date

2006-08-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32507867&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1572622(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2003-12-08 Application filed by Sepracor Inc filed Critical Sepracor Inc

2006-08-28 Application granted granted Critical

2006-08-28 Publication of DK1572622T3 publication Critical patent/DK1572622T3/da

Links

NDAUXUAQIAJITI-LBPRGKRZSA-N (R)-salbutamol Chemical compound CC(C)(C)NC[C@H](O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-LBPRGKRZSA-N 0.000 title abstract 2
229950008204 levosalbutamol Drugs 0.000 title abstract 2
FEWJPZIEWOKRBE-JCYAYHJZSA-L L-tartrate(2-) Chemical compound [O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O FEWJPZIEWOKRBE-JCYAYHJZSA-L 0.000 title 1
239000013078 crystal Substances 0.000 abstract 1
229940071648 metered dose inhaler Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/56—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups
- C07C215/58—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
- C07C215/60—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain the chain having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
- C07C59/255—Tartaric acid
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K3/00—Materials not provided for elsewhere
- C09K3/30—Materials not provided for elsewhere for aerosols
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0468—Liquids non-physiological
- A61M2202/0484—Alcohol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0468—Liquids non-physiological
- A61M2202/0488—Surfactant, e.g. for the lung
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Anesthesiology (AREA)
Biomedical Technology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Otolaryngology (AREA)
Dispersion Chemistry (AREA)
Materials Engineering (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Cosmetics (AREA)

DK03786896T 2002-12-10 2003-12-08 Anvendelse af levalbuterol-L-tartrat ved fremstilling af en doseringsinhalator DK1572622T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US43219502P	2002-12-10	2002-12-10

Publications (1)

Publication Number	Publication Date
DK1572622T3 true DK1572622T3 (da)	2006-08-28

Family

ID=32507867

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
DK03786896T DK1572622T3 (da)	2002-12-10	2003-12-08	Anvendelse af levalbuterol-L-tartrat ved fremstilling af en doseringsinhalator
DK06110646.4T DK1671942T4 (da)	2002-12-10	2003-12-08	Aerosolformulering omfattende levalbuterol L-tartratsalt
DK10176026.2T DK2292584T3 (en)	2002-12-10	2003-12-08	Pharmaceutical composition comprising levalbuterol L-hemitartrate salt as aerosol formulation

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
DK06110646.4T DK1671942T4 (da)	2002-12-10	2003-12-08	Aerosolformulering omfattende levalbuterol L-tartratsalt
DK10176026.2T DK2292584T3 (en)	2002-12-10	2003-12-08	Pharmaceutical composition comprising levalbuterol L-hemitartrate salt as aerosol formulation

Country Status (19)

Country	Link
US (8)	US7256310B2 (fr)
EP (3)	EP2292584B1 (fr)
JP (1)	JP4570960B2 (fr)
KR (3)	KR101166955B1 (fr)
AT (2)	ATE324364T1 (fr)
AU (1)	AU2003295695B2 (fr)
CA (1)	CA2507572C (fr)
CY (2)	CY1106315T1 (fr)
DE (2)	DE60336089D1 (fr)
DK (3)	DK1572622T3 (fr)
ES (3)	ES2361172T5 (fr)
IL (2)	IL168739A (fr)
MX (1)	MXPA05006087A (fr)
NO (1)	NO331649B1 (fr)
NZ (1)	NZ541168A (fr)
PL (1)	PL212725B1 (fr)
PT (3)	PT1572622E (fr)
SI (2)	SI1671942T2 (fr)
WO (1)	WO2004052835A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6466862B1 (en) *	1999-04-19	2002-10-15	Bruce DeKock	System for providing traffic information
US20070264202A1 (en) *	2004-09-09	2007-11-15	Cipla Limited	Pharmaceutical Composition Comprising an Isomer of Betamimetic Agent and an Anti-Cholinergic Agent
CA2591406A1 (fr) *	2004-12-17	2006-06-22	Cipla Limited	Composes et compositions pharmaceutiques
US7579505B2 (en)	2004-12-17	2009-08-25	Cipla Limited	Crystalline levosalbutamol sulphate and polymorphic forms thereof
US8542097B2 (en)	2011-04-13	2013-09-24	Jingle Technologies Llc	Systems and methods for transmitting information, alerts, and/or comments to participants based on location information
EP3042892A1 (fr)	2015-01-09	2016-07-13	Deva Holding Anonim Sirketi	L'amorphisation de tartrate de levosalbutamol
CN106727318A (zh) *	2016-12-22	2017-05-31	山东京卫制药有限公司	一种气雾剂及其制备方法
WO2021188809A1 (fr) *	2020-03-19	2021-09-23	Cai Gu Huang	Formulation inhalable d'une solution contenant du tartrate de lévalbutérol

Family Cites Families (25)

* Cited by examiner, † Cited by third party
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GB1200886A (en) *	1966-09-23	1970-08-05	Allen & Hanburys Ltd	Phenylaminoethanol derivatives
GB8828477D0 (en) †	1988-12-06	1989-01-05	Riker Laboratories Inc	Medical aerosol formulations
US5225183A (en)	1988-12-06	1993-07-06	Riker Laboratories, Inc.	Medicinal aerosol formulations
US5766573A (en)	1988-12-06	1998-06-16	Riker Laboratories, Inc.	Medicinal aerosol formulations
US5345980A (en)	1989-09-21	1994-09-13	Glaxo Group Limited	Method and apparatus an aerosol container
US5362755A (en)	1990-01-05	1994-11-08	Sepracor, Inc.	Method for treating asthma using optically pure (R)-albuterol
US5255183A (en) *	1990-05-29	1993-10-19	Interactive Voice Data System Inc.	Telephone-based personnel tracking system
DK1277467T3 (da) *	1991-06-10	2007-01-15	Schering Corp	Formuleringer af ikke-chlorfluorcarbonaerosoler
DK0617610T3 (da)	1991-12-18	1997-10-06	Minnesota Mining & Mfg	Suspensionsaerosolformuleringer.
US5545745A (en) *	1994-05-23	1996-08-13	Sepracor, Inc.	Enantioselective preparation of optically pure albuterol
US5399765A (en) *	1994-05-23	1995-03-21	Sepracor, Inc.	Enantioselective preparation of optically pure albuterol
SI0820279T1 (en) *	1995-04-14	2002-12-31	Smithkline Beecham Corporation	Metered dose inhaler for albuterol
US5603918A (en)	1995-06-09	1997-02-18	Boehringer Ingelheim Pharmaceuticals, Inc.	Aerosol composition of a salt of ipratropium and a salt of albuterol
US6040344A (en)	1996-11-11	2000-03-21	Sepracor Inc.	Formoterol process
US20010031244A1 (en) *	1997-06-13	2001-10-18	Chiesi Farmaceutici S.P.A.	Pharmaceutical aerosol composition
GB9806462D0 (en)	1998-03-26	1998-05-27	Glaxo Group Ltd	Improved compositions for inhalation
ATE283033T1 (de) *	1998-07-24	2004-12-15	Jago Res Ag	Medizinische aerosolformulierungen
EP1102579B1 (fr) *	1998-08-04	2003-03-19	Jago Research Ag	Formulations d'aerosol a usage medical
DK1283036T3 (da) *	1998-11-13	2008-03-25	Jagotec Ag	Törpulver til inhalation
CN1173929C (zh)	1999-10-19	2004-11-03	中国科学院成都有机化学研究所	光学纯肾上腺素类β-激动剂的组合拆分制备法
US6451289B2 (en)	2000-03-24	2002-09-17	Sepracor Inc.	Albuterol formulations
GB0030171D0 (en)	2000-12-11	2001-01-24	Cipla Ltd	Process for preparing isomers of salbutamol
ATE375142T1 (de) *	2001-03-30	2007-10-15	Jagotec Ag	Medizinische aerosolformulierungen
DE10120531A1 (de) *	2001-04-26	2002-10-31	Basf Ag	Neue Reaktivfarbstoffe und deren Verwendung zum Färben von Substraten, welche nucleophile Gruppen enthalten
CN1206205C (zh) *	2001-04-26	2005-06-15	中国科学院成都有机化学研究所	R－沙丁胺醇酒石酸盐的制备方法

2003
- 2003-12-08 KR KR1020087028024A patent/KR101166955B1/ko not_active Expired - Fee Related
- 2003-12-08 DK DK03786896T patent/DK1572622T3/da active
- 2003-12-08 JP JP2004559144A patent/JP4570960B2/ja not_active Expired - Fee Related
- 2003-12-08 PL PL377336A patent/PL212725B1/pl unknown
- 2003-12-08 DE DE60336089T patent/DE60336089D1/de not_active Expired - Lifetime
- 2003-12-08 EP EP10176026.2A patent/EP2292584B1/fr not_active Expired - Lifetime
- 2003-12-08 EP EP03786896A patent/EP1572622B1/fr not_active Expired - Lifetime
- 2003-12-08 SI SI200331954T patent/SI1671942T2/sl unknown
- 2003-12-08 KR KR1020107014278A patent/KR20100080865A/ko not_active Ceased
- 2003-12-08 AT AT03786896T patent/ATE324364T1/de active
- 2003-12-08 DE DE60304900T patent/DE60304900T2/de not_active Expired - Lifetime
- 2003-12-08 MX MXPA05006087A patent/MXPA05006087A/es active IP Right Grant
- 2003-12-08 EP EP06110646.4A patent/EP1671942B2/fr not_active Expired - Lifetime
- 2003-12-08 ES ES06110646.4T patent/ES2361172T5/es not_active Expired - Lifetime
- 2003-12-08 US US10/728,873 patent/US7256310B2/en not_active Expired - Lifetime
- 2003-12-08 SI SI200330331T patent/SI1572622T1/sl unknown
- 2003-12-08 PT PT03786896T patent/PT1572622E/pt unknown
- 2003-12-08 ES ES10176026.2T patent/ES2626648T3/es not_active Expired - Lifetime
- 2003-12-08 AU AU2003295695A patent/AU2003295695B2/en not_active Expired
- 2003-12-08 ES ES03786896T patent/ES2263051T3/es not_active Expired - Lifetime
- 2003-12-08 PT PT101760262T patent/PT2292584T/pt unknown
- 2003-12-08 CA CA2507572A patent/CA2507572C/fr not_active Expired - Lifetime
- 2003-12-08 AT AT06110646T patent/ATE498604T1/de active
- 2003-12-08 DK DK06110646.4T patent/DK1671942T4/da active
- 2003-12-08 DK DK10176026.2T patent/DK2292584T3/en active
- 2003-12-08 NZ NZ541168A patent/NZ541168A/en not_active IP Right Cessation
- 2003-12-08 PT PT06110646T patent/PT1671942E/pt unknown
- 2003-12-08 KR KR1020057010435A patent/KR20050088307A/ko not_active Ceased
- 2003-12-08 WO PCT/US2003/037079 patent/WO2004052835A1/fr not_active Ceased
2005
- 2005-05-23 IL IL168739A patent/IL168739A/en active IP Right Grant
- 2005-07-08 NO NO20053339A patent/NO331649B1/no not_active IP Right Cessation
2006
- 2006-07-03 CY CY20061100912T patent/CY1106315T1/el unknown
2007
- 2007-08-08 US US11/891,048 patent/US20080119564A1/en not_active Abandoned
2010
- 2010-07-09 US US12/833,882 patent/US20100272654A1/en not_active Abandoned
2011
- 2011-03-11 CY CY20111100273T patent/CY1111330T1/el unknown
- 2011-04-14 IL IL212369A patent/IL212369A/en active IP Right Grant
2012
- 2012-10-02 US US13/633,801 patent/US20130028845A1/en not_active Abandoned
2013
- 2013-04-29 US US13/873,084 patent/US8765153B2/en not_active Expired - Lifetime
2014
- 2014-05-21 US US14/283,754 patent/US20150071969A1/en not_active Abandoned
2016
- 2016-01-22 US US15/003,883 patent/US20160368858A1/en not_active Abandoned
2017
- 2017-10-18 US US15/786,917 patent/US20180222845A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP1671942B1 (fr)	2011-02-16
ES2361172T5 (es)	2014-09-22
DE60304900D1 (de)	2006-06-01
EP2292584A1 (fr)	2011-03-09
ATE498604T1 (de)	2011-03-15
PT1572622E (pt)	2006-08-31
CA2507572A1 (fr)	2004-06-24
EP1572622B1 (fr)	2006-04-26
KR101166955B1 (ko)	2012-07-19
ATE324364T1 (de)	2006-05-15
US20130236515A1 (en)	2013-09-12
EP1572622A1 (fr)	2005-09-14
PL212725B1 (pl)	2012-11-30
ES2626648T3 (es)	2017-07-25
US20150071969A1 (en)	2015-03-12
JP2006509802A (ja)	2006-03-23
NZ541168A (en)	2008-10-31
CY1111330T1 (el)	2015-08-05
AU2003295695A1 (en)	2004-06-30
US8765153B2 (en)	2014-07-01
WO2004052835A1 (fr)	2004-06-24
AU2003295695B2 (en)	2009-08-20
PT2292584T (pt)	2017-06-12
DE60304900T2 (de)	2006-10-19
PT1671942E (pt)	2011-05-11
IL212369A (en)	2013-08-29
IL168739A (en)	2011-06-30
DK2292584T3 (en)	2017-05-01
DK1671942T4 (da)	2014-09-22
NO20053339L (no)	2005-09-07
CA2507572C (fr)	2011-04-19
EP2292584B1 (fr)	2017-03-01
KR20100080865A (ko)	2010-07-12
US20040115136A1 (en)	2004-06-17
NO20053339D0 (no)	2005-07-08
US20130028845A1 (en)	2013-01-31
SI1671942T2 (sl)	2014-10-30
DE60336089D1 (de)	2011-03-31
ES2263051T3 (es)	2006-12-01
EP1671942A1 (fr)	2006-06-21
DK1671942T3 (da)	2011-04-26
JP4570960B2 (ja)	2010-10-27
US20160368858A1 (en)	2016-12-22
US7256310B2 (en)	2007-08-14
PL377336A1 (pl)	2006-01-23
US20180222845A1 (en)	2018-08-09
NO331649B1 (no)	2012-02-13
CY1106315T1 (el)	2011-10-12
KR20080103614A (ko)	2008-11-27
SI1572622T1 (sl)	2006-10-31
ES2361172T3 (es)	2011-06-14
KR20050088307A (ko)	2005-09-05
EP1671942B2 (fr)	2014-07-23
MXPA05006087A (es)	2005-09-30
IL212369A0 (en)	2011-06-30
US20080119564A1 (en)	2008-05-22
US20100272654A1 (en)	2010-10-28
SI1671942T1 (sl)	2011-04-29

Publication	Publication Date	Title
PL369072A1 (en)	2005-04-18	Metered dose inhaler
CY2009009I2 (el)	2014-04-09	Σταθερες φαρμακευτικες φαρμακοτεχνικες μορφες διαλυματος για υπο πιεση μετρημενης δοσης συσκευες εισπνοης
NO20032836D0 (no)	2003-06-20	Utmålt-dose-inhalator for salmeterol-xinafoat
ZA200709345B (en)	2008-10-29	Dose counter for metered dose inhalers
DE60224111D1 (de)	2008-01-24	Bausatz zur Herstellung einer Verabreichungsform zur Abgabe einer bioaktiven Substanz
BRPI0417717A (pt)	2007-04-03	composto, composição farmacêutica, e, uso de um composto
EA200601837A1 (ru)	2007-04-27	Бензоксазины для лечения заболеваний дыхательных путей
DE60336225D1 (de)	2011-04-14	Neue pharmazeutische zusammenstezungen, flibanserin polymorph a enthaltend
GB0328630D0 (en)	2004-01-14	Metered dose inhalation preparations
DK1229953T3 (da)	2007-04-10	Inhalationsaktiveret anordning til anvendelse med inhalatorer med afmålt dosis (MDI)
DK1283708T3 (da)	2005-12-27	Anvendelse af biguanidderivater til fremstilling af et medikament med sårhelingsvirkning
IL212369A0 (en)	2011-06-30	A metered dose inhaler comprising a canister containing an aerosol formulation comprising levalbuterol l-tartrate, and use of levalbuterol l-tartrate in the manufacture of said metered dose inhaler for treating bronchospasm.
DE602004022810D1 (de)	2009-10-08	Mehrdosis-inhalator
EA200602016A1 (ru)	2007-06-29	ПОРОШКОВЫЕ КОМПОЗИЦИИ ДЛЯ ИНГАЛЯЦИИ, СОДЕРЖАЩИЕ ЭНАНТИОМЕРНОЧИСТЫЕ β-АГОНИСТЫ
EP1757282A4 (fr)	2010-02-10	Utilisation de composes de kaurane dans l'elaboration d'un medicament
NZ528164A (en)	2006-03-31	Use of flumazenil to produce a medicament for the treatment of cocaine dependency
BRPI0409175A (pt)	2006-04-11	preparação farmacêutica oral para antagonistas de bombeamento de próton
DE60114597D1 (de)	2005-12-08	Naphthamid-neurokinin antagonisten zur verwendung als medikamente
GB0226274D0 (en)	2002-12-18	Metered dose inhalation preparations
IL177103A0 (en)	2006-12-10	Stable pharmaceutical solution formulations for pressurized metered dose inhalers
GB0328629D0 (en)	2004-01-14	Metered dose inhalation preparations
GB0314727D0 (en)	2003-07-30	Spacers for use with metered dose inhalers
AU2002236091A1 (en)	2002-09-24	Canisters for use in metered dose inhalers
ZA200606577B (en)	2009-04-29	Stable pharmaceutical solution formulations for pressurized metered dose inhalers
ATE493976T1 (de)	2011-01-15	Bakuchiol enthaltende pharmazeutische zusammensetzung zur behandlung von weiblicher osteoporose