DK1579914T3 - Brøndpladereaktor - Google Patents

Brøndpladereaktor

Info

Publication number
DK1579914T3
DK1579914T3 DK05250761.3T DK05250761T DK1579914T3 DK 1579914 T3 DK1579914 T3 DK 1579914T3 DK 05250761 T DK05250761 T DK 05250761T DK 1579914 T3 DK1579914 T3 DK 1579914T3
Authority
DK
Denmark
Prior art keywords
well
temperature
level
well plate
wells
Prior art date
Application number
DK05250761.3T
Other languages
English (en)
Inventor
David L Klein
Gregory Andronaco
Stephen G Boyer
Original Assignee
Microreactor Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microreactor Technologies Inc filed Critical Microreactor Technologies Inc
Application granted granted Critical
Publication of DK1579914T3 publication Critical patent/DK1579914T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/12Well or multiwell plates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/38Caps; Covers; Plugs; Pouring means
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14Process control and prevention of errors
    • B01L2200/143Quality control, feedback systems
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/046Function or devices integrated in the closure
    • B01L2300/049Valves integrated in closure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0663Whole sensors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0829Multi-well plates; Microtitration plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/10Means to control humidity and/or other gases
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Rigid containers without fluid transport within
    • B01L3/5085Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • B01L3/50851Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Rigid containers without fluid transport within
    • B01L3/5085Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • B01L3/50853Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates with covers or lids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/20Oxygen containing
    • Y10T436/207497Molecular oxygen
    • Y10T436/209163Dissolved or trace oxygen or oxygen content of a sealed environment

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Devices And Processes Conducted In The Presence Of Fluids And Solid Particles (AREA)
  • Paper (AREA)
  • Steering Control In Accordance With Driving Conditions (AREA)
DK05250761.3T 2004-02-11 2005-02-10 Brøndpladereaktor DK1579914T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/777,581 US7374725B2 (en) 2004-02-11 2004-02-11 Well plate reactor

Publications (1)

Publication Number Publication Date
DK1579914T3 true DK1579914T3 (da) 2010-03-29

Family

ID=34827521

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05250761.3T DK1579914T3 (da) 2004-02-11 2005-02-10 Brøndpladereaktor

Country Status (5)

Country Link
US (4) US7374725B2 (da)
EP (1) EP1579914B1 (da)
AT (1) ATE454216T1 (da)
DE (1) DE602005018702D1 (da)
DK (1) DK1579914T3 (da)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007522801A (ja) * 2004-01-07 2007-08-16 リーブテック,インコーポレイテッド 一体のスパージャーとセンサー受け器を有する混合用袋
US7374725B2 (en) * 2004-02-11 2008-05-20 Gener8, Inc. Well plate reactor
US7622296B2 (en) * 2004-05-28 2009-11-24 Wafergen, Inc. Apparatus and method for multiplex analysis
US20100261288A1 (en) * 2005-06-13 2010-10-14 Fortebio, Inc. Tip tray assembly for optical sensors
US7851204B2 (en) * 2006-06-09 2010-12-14 Pall Microreactor Technologies, Inc. Closure for milliliter scale bioreactor
CA2754719C (en) * 2006-08-10 2013-12-31 Allen C. Barnes Portable biological testing device and method
EP2091644B1 (en) * 2006-11-09 2018-04-18 ASMAG-Holding GmbH Titer plate with thin-film-light sensor
EP2109627A4 (en) 2007-01-22 2014-07-23 Wafergen Inc DEVICE FOR CHEMICAL REACTIONS WITH HIGH THROUGHPUT
US7733488B1 (en) * 2007-01-26 2010-06-08 Revolution Optics, Llc Compact multi-wavelength optical reader and method of acquiring optical data on clustered assay samples using differing-wavelength light sources
DE202007002538U1 (de) * 2007-02-21 2007-06-06 Krebs, Torsten Begasungsvorrichtung und -system
WO2008106515A1 (en) * 2007-02-27 2008-09-04 The Board Of Trustees Of The University Of Illinois Insert device for multiwell plate
FR2916451A1 (fr) * 2007-05-25 2008-11-28 Mhs Ind Soc Par Actions Simpli Systeme de culture de cellules biologiques
US20080311614A1 (en) * 2007-06-15 2008-12-18 Wyeth Methods for measuring ph in a small-scale cell culture system and predicting performance of cells in a large-scale culture system
US9192932B2 (en) * 2007-06-20 2015-11-24 Labcyte Inc. Closures which contain reservoirs and allow acoustic ejection
KR100822672B1 (ko) * 2007-06-27 2008-04-17 (주)실리콘화일 이미지센서를 이용한 진단장치 및 그 제조방법
DE102008001322A1 (de) * 2008-04-22 2009-10-29 Linos Photonics Gmbh & Co. Kg System zur optischen Analyse von Probenarrays
FR2934371B1 (fr) * 2008-07-25 2012-06-08 Nanotec Solution Dispositif capteur de biomasse a usage unique, procede de realisation de ce dispositif et bioreacteur a usage unique integrant ce capteur
WO2010125665A1 (ja) * 2009-04-30 2010-11-04 エイブル株式会社 リアクター
WO2011137058A1 (en) * 2010-04-30 2011-11-03 Merck Sharp & Dohme Corp. Multiwell-plate reactor and system therefor
WO2012156682A1 (en) * 2011-05-16 2012-11-22 Parker Hannifin Manufacturing Limited Bioreactor chamber
US20140329332A1 (en) * 2011-11-22 2014-11-06 Luxcel Biosciences Ltd. Device and method for rapid assay of multiple biological samples for oxygen consumption
US20150031570A1 (en) * 2012-02-04 2015-01-29 Douglas Scientific, LLC Method and apparatus for rapid, high sensitivity analysis of low volume samples of biological materials
CN103920551B (zh) * 2014-04-29 2015-09-16 中国人民解放军第三军医大学第三附属医院 玻璃电极存储装置
WO2016134342A1 (en) 2015-02-20 2016-08-25 Wafergen, Inc. Method for rapid accurate dispensing, visualization and analysis of single cells
WO2016168445A1 (en) 2015-04-17 2016-10-20 Pion Inc. Apparatus and method for the assessment of concentration profiling and permeability rates
US10240118B2 (en) * 2015-04-30 2019-03-26 Mark Langley System for monitoring growth media
WO2017018221A1 (ja) * 2015-07-30 2017-02-02 株式会社日立ハイテクノロジーズ 発光分析用検出装置および自動分析装置
US9952122B2 (en) 2015-08-03 2018-04-24 Palo Alto Research Center Incorporated Polysensing bioelectronic test plate
EP3239285B1 (de) * 2016-04-27 2019-01-30 Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen Vorrichtung zur ermittlung und überwachung der physiologischen zustände von mikrobiellen kulturen in jedem einzelnen mikrobioreaktor einer mikrotiterplatte
US11460405B2 (en) 2016-07-21 2022-10-04 Takara Bio Usa, Inc. Multi-Z imaging and dispensing with multi-well devices
JP6868242B2 (ja) * 2017-03-01 2021-05-12 クアーズテック株式会社 細胞培養モジュール
DE102017107033A1 (de) * 2017-03-31 2018-11-22 Presens Precision Sensing Gmbh Vorrichtung, verfahren und system zur parallelisierten erfassung mindestens einer veränderlichen während eines biologisch / chemischen prozesses
WO2018213275A1 (en) 2017-05-16 2018-11-22 Agilent Technologies, Inc. Headspace eliminating microtiter plate lid and method of optically measuring well oxygen concentration through the lid
WO2020041765A1 (en) * 2018-08-24 2020-02-27 Polybiomics, Inc. Integrated platforms for precise poly-sensing and imaging
US11298701B2 (en) 2018-11-26 2022-04-12 King Instrumentation Technologies Microtiter plate mixing control system
EP4200404A4 (en) * 2020-10-22 2025-01-01 The Regents of University of California DEVICES AND METHODS FOR ASSESSING THE VIABILITY OF EMBRYOS
EP4298196A2 (en) * 2021-02-28 2024-01-03 Melonfrost, Inc. Bioreactor systems, and related methods and apparatus
CN117441007A (zh) * 2021-05-07 2024-01-23 贝克曼库尔特有限公司 对平行培养孔中ph的控制
GB2635651A (en) * 2023-10-20 2025-05-28 Cambridge Consultants Optical sensing

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US797796A (en) 1905-01-24 1905-08-22 John T Scott Hose or pipe coupling.
US4618170A (en) 1985-11-26 1986-10-21 Fishburne Francis B Coupled pipes and sealed unions therefor
DE19646505A1 (de) * 1996-11-12 1998-05-14 Itt Ind Gmbh Deutsche Vorrichtung zur Durchführung von Untersuchungen an Zellproben und dergleichen
WO1999006821A1 (de) * 1997-08-01 1999-02-11 Presens Precision Sensing Gmbh Verfahren und vorrichtung zur referenzierung von fluoreszenzintensitätssignalen
EP1064353B1 (en) * 1998-03-18 2002-11-06 Massachusetts Institute Of Technology Vascularized perfused microtissue/micro-organ arrays
DE01961662T1 (de) * 2000-08-14 2007-05-03 University Of Maryland Baltimore County Bioreaktor und bioverfahrenstechnik
US7070740B1 (en) 2000-09-28 2006-07-04 Beckman Coulter, Inc. Method and apparatus for processing biomolecule arrays
US6635441B2 (en) * 2001-02-08 2003-10-21 Irm, Llc Multi-sample fermentor and method of using same
EP1499705A2 (en) 2002-05-01 2005-01-26 Massachusetts Institute of Technology Microfermentors for rapid screening and analysis of biochemical processes
US7211224B2 (en) * 2002-05-23 2007-05-01 Millipore Corporation One piece filtration plate
CA2391641A1 (fr) * 2002-06-28 2003-12-28 Robert Longin Plateforme robotisee de cultures cellulaires en batteries de reacteurs miniaturises, equipee d'un systeme de mesure en temps reel de la turbidite cellulaire ou toutes autres proprietes optiques
ES2208127B1 (es) 2002-11-28 2005-09-01 Universitat Politecnica De Catalunya Sistema modular de multiples minibiorreactores automatizados para screenning multifuncional (hts) en biotecnologia.
US7374725B2 (en) * 2004-02-11 2008-05-20 Gener8, Inc. Well plate reactor

Also Published As

Publication number Publication date
US7713486B2 (en) 2010-05-11
US20050176155A1 (en) 2005-08-11
EP1579914A2 (en) 2005-09-28
US20080118403A1 (en) 2008-05-22
US20100184199A1 (en) 2010-07-22
US7887766B2 (en) 2011-02-15
DE602005018702D1 (de) 2010-02-25
ATE454216T1 (de) 2010-01-15
US7718134B2 (en) 2010-05-18
EP1579914B1 (en) 2010-01-06
US20080131972A1 (en) 2008-06-05
EP1579914A3 (en) 2006-04-19
US7374725B2 (en) 2008-05-20

Similar Documents

Publication Publication Date Title
DE602005018702D1 (de) Reaktor mit Muldenplatte
Alster et al. Embracing a new paradigm for temperature sensitivity of soil microbes
WO2008036121A3 (en) Portable reactor for real-time nucleic acid amplification and detection
CN106536711B (zh) 模块化培养器系统
Ifrim et al. Dynamic pH model for autotrophic growth of microalgae in photobioreactor: A tool for monitoring and control purposes
NZ580373A (en) Thermal cylcer system with temperature control element and a controller to control a thermostate's temperature based on a sample in a sample chamber
EP1600043A4 (en) ANALYTICAL OVEN WITH PREDICTIVE TEMPERATURE CONTROL
TW200728488A (en) Apparatus temperature control and pattern compensation
TW200509182A (en) Substrate support having temperature controlled substrate support surface
MX2012012172A (es) Metodo y aparato de control de temperatura.
Cogne et al. Design, operation, and modeling of a membrane photobioreactor to study the growth of the cyanobacterium Arthrospira platensis in space conditions
UA95466C2 (ru) Способ управления охлаждением технической установки
EP2008717A3 (en) Reaction device with accurate temperature control
US8393234B2 (en) Apparatus, device and method for arranging at least one sample container
US20250135456A1 (en) Autonomous microfluidic device for water quality analysis
GB2467478A (en) Temperature maintenance system for a sensor
DE50113158D1 (de) Kalorimeter
ATE537847T1 (de) Biologische vorrichtung zur regulierung der genexpression
Khanahmadi et al. Investigating the use of cooling surfaces in solid‐state fermentation tray bioreactors: modelling and experimentation
WO2014060360A1 (en) Embryo incubator incorporating gas control
MXPA06014115A (es) Sistema y metodo para analizar el crecimiento microbiano.
Carius et al. Model‐based derivation, analysis and control of unstable microaerobic steady‐states—considering Rhodospirillum rubrum as an example
Fenner et al. A novel approach to studying the effects of temperature on soil biogeochemistry using a thermal gradient bar
CA2449696A1 (en) Method and apparatus for heating a slurry to a predetermined temperature
TW200702204A (en) Thermal print head with temperature control function