DK1596879T3 - Anvendelse af kahalalidforbindelser til fremstilling af et medikament til behandling af psoriasis - Google Patents

Anvendelse af kahalalidforbindelser til fremstilling af et medikament til behandling af psoriasis

Info

Publication number: DK1596879T3
Authority: DK; Denmark
Prior art keywords: psoriasis; medicament; manufacture; treatment; kahalalide
Prior art date: 2003-02-26

Application number

DK04714847.3T

Other languages

English (en)

Inventor

Delso Miguel Angel Izquierdo

Original Assignee

Pharma Mar Sau

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-02-26

Filing date

2004-02-26

Publication date

2011-04-11

2004-02-26 Application filed by Pharma Mar Sau filed Critical Pharma Mar Sau

2011-04-11 Application granted granted Critical

2011-04-11 Publication of DK1596879T3 publication Critical patent/DK1596879T3/da

Links

201000004681 Psoriasis Diseases 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 title abstract 2
229930194861 kahalalide Natural products 0.000 title abstract 2
239000003814 drug Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
RCGXNDQKCXNWLO-WLEIXIPESA-N (2r)-n-[(2s)-5-amino-1-[[(2r,3r)-1-[[(3s,6z,9s,12r,15r,18r,19s)-9-benzyl-15-[(2r)-butan-2-yl]-6-ethylidene-19-methyl-2,5,8,11,14,17-hexaoxo-3,12-di(propan-2-yl)-1-oxa-4,7,10,13,16-pentazacyclononadec-18-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopent Chemical compound N([C@@H](CCCN)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@H]1C(N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)NC(/C(=O)N[C@H](C(=O)O[C@H]1C)C(C)C)=C\C)C(C)C)[C@H](C)CC)=O)C(=O)[C@H]1CCCN1C(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)CCCC(C)C)C(C)C)[C@@H](C)O)C(C)C)C(C)C RCGXNDQKCXNWLO-WLEIXIPESA-N 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
108010091711 kahalalide F Proteins 0.000 abstract 1
208000017520 skin disease Diseases 0.000 abstract 1
230000001988 toxicity Effects 0.000 abstract 1
231100000419 toxicity Toxicity 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Immunology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Medicinal Preparation (AREA)

DK04714847.3T 2003-02-26 2004-02-26 Anvendelse af kahalalidforbindelser til fremstilling af et medikament til behandling af psoriasis DK1596879T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0304367.6A GB0304367D0 (en)	2003-02-26	2003-02-26	Methods for treating psoriasis
PCT/GB2004/000757 WO2004075910A1 (en)	2003-02-26	2004-02-26	Use of kahalalide compounds for the manufacture of a medicament for the treatment of psoriasis

Publications (1)

Publication Number	Publication Date
DK1596879T3 true DK1596879T3 (da)	2011-04-11

Family

ID=9953685

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK04714847.3T DK1596879T3 (da)	2003-02-26	2004-02-26	Anvendelse af kahalalidforbindelser til fremstilling af et medikament til behandling af psoriasis

Country Status (17)

Country	Link
US (2)	US7323444B2 (da)
EP (1)	EP1596879B1 (da)
JP (1)	JP4800194B2 (da)
AT (1)	ATE492285T1 (da)
AU (1)	AU2004216443B2 (da)
CA (1)	CA2516458C (da)
CY (1)	CY1111353T1 (da)
DE (1)	DE602004030661D1 (da)
DK (1)	DK1596879T3 (da)
ES (1)	ES2358018T3 (da)
GB (1)	GB0304367D0 (da)
MX (1)	MXPA05009029A (da)
NZ (1)	NZ541493A (da)
PT (1)	PT1596879E (da)
RU (1)	RU2356908C2 (da)
SI (1)	SI1596879T1 (da)
WO (1)	WO2004075910A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0002952D0 (en) *	2000-02-09	2000-03-29	Pharma Mar Sa	Process for producing kahalalide F compounds
GB0304367D0 (en) *	2003-02-26	2003-04-02	Pharma Mar Sau	Methods for treating psoriasis
US7507708B2 (en)	2003-02-26	2009-03-24	Pharma Mar, S.A.U.	Antitumoral compounds
GB0321066D0 (en) *	2003-09-09	2003-10-08	Pharma Mar Sau	New antitumoral compounds
CN101861159A (zh) *	2007-10-19	2010-10-13	马尔药品公司	改进的抗肿瘤治疗
EP2252315A1 (en) *	2008-01-30	2010-11-24	Pharma Mar, S.A.	Improved antitumoral treatments
AU2009221120A1 (en) *	2008-03-07	2009-09-11	Pharma Mar, S.A.	Improved antitumoral treatments
LT3615544T (lt)	2017-04-27	2023-05-10	Pharma Mar S.A.	Priešnavikiniai junginiai

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US4943533A (en) *	1984-03-01	1990-07-24	The Regents Of The University Of California	Hybrid cell lines that produce monoclonal antibodies to epidermal growth factor receptor
JPS6178719A (ja) *	1984-09-25	1986-04-22	Tanabe Seiyaku Co Ltd	総合輸液剤
GR870129B (en)	1987-01-27	1987-02-04	Giatzidis Ippokratis	Stable bicarbonate - glycylglycine dialysate for hemodialysis and peritoneal dialysis
US4853388A (en) *	1987-05-15	1989-08-01	Pearlman Dale L	Method for treating psoriasis with cytotoxic agents
US5399363A (en) *	1991-01-25	1995-03-21	Eastman Kodak Company	Surface modified anticancer nanoparticles
AU658396B2 (en) *	1991-03-06	1995-04-13	Merck Patent Gesellschaft Mit Beschrankter Haftung	Humanized and chimeric monoclonal antibodies
EP0567626B1 (en) *	1991-11-19	2001-09-19	Amylin Pharmaceuticals, Inc.	Amylin agonist peptides and uses therefor
US5849704A (en)	1991-12-20	1998-12-15	Novo Nordisk A/S	Pharmaceutical formulation
AU661533B2 (en) *	1992-01-20	1995-07-27	Astrazeneca Ab	Quinazoline derivatives
GB9302046D0 (en) *	1993-02-03	1993-03-24	Pharma Mar Sa	Antiumoral compound-v
US6274551B1 (en) *	1994-02-03	2001-08-14	Pharmamar, S.A.	Cytotoxic and antiviral compound
US5932189A (en)	1994-07-29	1999-08-03	Diatech, Inc.	Cyclic peptide somatostatin analogs
US5705511A (en) *	1994-10-14	1998-01-06	Cephalon, Inc.	Fused pyrrolocarbazoles
GB9508538D0 (en) *	1995-04-27	1995-06-14	Zeneca Ltd	Quinazoline derivatives
US5747498A (en) *	1996-05-28	1998-05-05	Pfizer Inc.	Alkynyl and azido-substituted 4-anilinoquinazolines
JP3927248B2 (ja)	1995-07-11	2007-06-06	第一製薬株式会社	Ｈｇｆ凍結乾燥製剤
US6391874B1 (en) *	1996-07-13	2002-05-21	Smithkline Beecham Corporation	Fused heterocyclic compounds as protein tyrosine kinase inhibitors
US6235883B1 (en) *	1997-05-05	2001-05-22	Abgenix, Inc.	Human monoclonal antibodies to epidermal growth factor receptor
WO1998050406A1 (en)	1997-05-09	1998-11-12	The General Hospital Corporation	Cell proliferation related genes
RS49779B (sr) *	1998-01-12	2008-06-05	Glaxo Group Limited,	Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
GB9803448D0 (en)	1998-02-18	1998-04-15	Pharma Mar Sa	Pharmaceutical formulation
US6200598B1 (en) *	1998-06-18	2001-03-13	Duke University	Temperature-sensitive liposomal formulation
CN1160338C (zh) *	1998-11-19	2004-08-04	沃尼尔·朗伯公司	N-[4-(3-氯-4-氟-苯基氨基)-7-(3-吗啉-4-基-丙氧基)-喹唑啉-6-基]-丙烯酰胺,不可逆的酪氨酸激酶抑制剂
US7311924B2 (en) *	1999-04-01	2007-12-25	Hana Biosciences, Inc.	Compositions and methods for treating cancer
UA74803C2 (uk) *	1999-11-11	2006-02-15	Осі Фармасьютікалз, Інк.	Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування
GB0002952D0 (en)	2000-02-09	2000-03-29	Pharma Mar Sa	Process for producing kahalalide F compounds
JP2004514407A (ja)	2000-04-28	2004-05-20	ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア	異種キャプシド中にシュードタイピングされたａａｖ５キャプシドおよびａａｖ５ベクターを含む組換えａａｖベクター
US6440465B1 (en) *	2000-05-01	2002-08-27	Bioderm, Inc.	Topical composition for the treatment of psoriasis and related skin disorders
US7473681B2 (en)	2000-10-31	2009-01-06	Pharma Mar, S.A.	Kahalalide F
US20050054555A1 (en)	2001-10-19	2005-03-10	Jose Jimeno	Kahalalide compounds for use in cancer therapy
EP1435990A1 (en)	2001-10-19	2004-07-14	Pharma Mar, S.A.	Kahalalide compounds for use in cancer therapy
GB0304367D0 (en) *	2003-02-26	2003-04-02	Pharma Mar Sau	Methods for treating psoriasis
CN101077885A (zh) *	2002-10-18	2007-11-28	马尔药品公司	新型抗肿瘤化合物
US7507708B2 (en) *	2003-02-26	2009-03-24	Pharma Mar, S.A.U.	Antitumoral compounds
GB0321066D0 (en)	2003-09-09	2003-10-08	Pharma Mar Sau	New antitumoral compounds
GB0408958D0 (en)	2004-04-22	2004-05-26	Pharma Mar Sa	Convergent synthesis for kahalalide compounds

2003
- 2003-02-26 GB GBGB0304367.6A patent/GB0304367D0/en not_active Ceased
- 2003-10-20 RU RU2005115102/04A patent/RU2356908C2/ru not_active IP Right Cessation
2004
- 2004-02-26 EP EP04714847A patent/EP1596879B1/en not_active Expired - Lifetime
- 2004-02-26 DE DE602004030661T patent/DE602004030661D1/de not_active Expired - Lifetime
- 2004-02-26 SI SI200431619T patent/SI1596879T1/sl unknown
- 2004-02-26 AT AT04714847T patent/ATE492285T1/de active
- 2004-02-26 DK DK04714847.3T patent/DK1596879T3/da active
- 2004-02-26 US US10/546,758 patent/US7323444B2/en not_active Expired - Fee Related
- 2004-02-26 ES ES04714847T patent/ES2358018T3/es not_active Expired - Lifetime
- 2004-02-26 NZ NZ541493A patent/NZ541493A/en not_active IP Right Cessation
- 2004-02-26 MX MXPA05009029A patent/MXPA05009029A/es active IP Right Grant
- 2004-02-26 AU AU2004216443A patent/AU2004216443B2/en not_active Ceased
- 2004-02-26 WO PCT/GB2004/000757 patent/WO2004075910A1/en not_active Ceased
- 2004-02-26 PT PT04714847T patent/PT1596879E/pt unknown
- 2004-02-26 JP JP2006502323A patent/JP4800194B2/ja not_active Expired - Fee Related
- 2004-02-26 CA CA2516458A patent/CA2516458C/en not_active Expired - Fee Related
2007
- 2007-12-04 US US11/950,144 patent/US20080090757A1/en not_active Abandoned
2011
- 2011-03-22 CY CY20111100314T patent/CY1111353T1/el unknown

Also Published As

Publication number	Publication date
CA2516458C (en)	2012-11-27
US20080090757A1 (en)	2008-04-17
EP1596879A1 (en)	2005-11-23
CY1111353T1 (el)	2015-08-05
MXPA05009029A (es)	2005-11-23
AU2004216443B2 (en)	2009-03-19
AU2004216443A1 (en)	2004-09-10
JP2007527851A (ja)	2007-10-04
EP1596879B1 (en)	2010-12-22
ES2358018T3 (es)	2011-05-04
US7323444B2 (en)	2008-01-29
ATE492285T1 (de)	2011-01-15
RU2005115102A (ru)	2006-02-27
SI1596879T1 (sl)	2011-07-29
WO2004075910A1 (en)	2004-09-10
US20070032412A1 (en)	2007-02-08
PT1596879E (pt)	2011-02-23
DE602004030661D1 (de)	2011-02-03
GB0304367D0 (en)	2003-04-02
NZ541493A (en)	2008-07-31
RU2356908C2 (ru)	2009-05-27
CA2516458A1 (en)	2004-09-10
JP4800194B2 (ja)	2011-10-26

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