DK1606406T3 - Korte interfererende RNA (siRNA) analoger - Google Patents

Korte interfererende RNA (siRNA) analoger

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Publication number
DK1606406T3
DK1606406T3 DK04722233T DK04722233T DK1606406T3 DK 1606406 T3 DK1606406 T3 DK 1606406T3 DK 04722233 T DK04722233 T DK 04722233T DK 04722233 T DK04722233 T DK 04722233T DK 1606406 T3 DK1606406 T3 DK 1606406T3
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DK
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Prior art keywords
sirna
analogues
short interfering
lna
nucleic acid
Prior art date
Application number
DK04722233T
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English (en)
Other versions
DK1606406T4 (da
Inventor
Claes Wahlestedt
Zicai Liang
Joacim Elmen
Troels Koch
Anders Malling Soerensen
Henrik Oerum
Original Assignee
Santaris Pharma As
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44597267&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1606406(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Santaris Pharma As filed Critical Santaris Pharma As
Application granted granted Critical
Publication of DK1606406T3 publication Critical patent/DK1606406T3/da
Publication of DK1606406T4 publication Critical patent/DK1606406T4/da

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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
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DK04722233.6T 2003-03-21 2004-03-22 Short Interfering RNA (siRNA) Analogues DK1606406T4 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US45688803P 2003-03-21 2003-03-21
DKPA200300442 2003-03-21
DKPA200301625 2003-10-31
DKPA200400145 2004-01-30
PCT/DK2004/000192 WO2004083430A2 (en) 2003-03-21 2004-03-22 SHORT INTERFERING RNA (siRNA) ANALOGUES

Publications (2)

Publication Number Publication Date
DK1606406T3 true DK1606406T3 (da) 2009-12-14
DK1606406T4 DK1606406T4 (da) 2013-12-16

Family

ID=44597267

Family Applications (2)

Application Number Title Priority Date Filing Date
DK09169380.4T DK2141234T3 (da) 2003-03-21 2004-03-22 Korte interfererende RNA (siRNA) analoger
DK04722233.6T DK1606406T4 (da) 2003-03-21 2004-03-22 Short Interfering RNA (siRNA) Analogues

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK09169380.4T DK2141234T3 (da) 2003-03-21 2004-03-22 Korte interfererende RNA (siRNA) analoger

Country Status (10)

Country Link
US (3) US8653252B2 (da)
EP (2) EP1606406B2 (da)
JP (1) JP4755972B2 (da)
AT (1) ATE443765T1 (da)
AU (1) AU2004221760B2 (da)
CA (1) CA2519860C (da)
DE (1) DE602004023279D1 (da)
DK (2) DK2141234T3 (da)
ES (2) ES2576677T3 (da)
WO (1) WO2004083430A2 (da)

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US7812149B2 (en) 1996-06-06 2010-10-12 Isis Pharmaceuticals, Inc. 2′-Fluoro substituted oligomeric compounds and compositions for use in gene modulations
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EP2213737B1 (en) 2002-02-01 2012-11-07 Life Technologies Corporation Double-stranded oligonucleotides
US20030166282A1 (en) 2002-02-01 2003-09-04 David Brown High potency siRNAS for reducing the expression of target genes
US8604183B2 (en) 2002-11-05 2013-12-10 Isis Pharmaceuticals, Inc. Compositions comprising alternating 2′-modified nucleosides for use in gene modulation
GB0228540D0 (en) * 2002-12-06 2003-01-15 Glaxo Group Ltd Novel compositions
US20050233342A1 (en) * 2003-03-07 2005-10-20 Muthiah Manoharan Methods of preventing off-target gene silencing
EP1644475A4 (en) 2003-06-20 2009-06-03 Isis Pharmaceuticals Inc DOUBLE-STRAND COMPOSITIONS WITH A 3'-ENDO-MODIFIED STRING FOR USE IN GENE MODULATION
WO2005073378A1 (en) * 2004-01-30 2005-08-11 Santaris Pharma A/S MODIFIED SHORT INTERFERING RNA (MODIFIED siRNA)
US8569474B2 (en) 2004-03-09 2013-10-29 Isis Pharmaceuticals, Inc. Double stranded constructs comprising one or more short strands hybridized to a longer strand
US8394947B2 (en) 2004-06-03 2013-03-12 Isis Pharmaceuticals, Inc. Positionally modified siRNA constructs
US7884086B2 (en) 2004-09-08 2011-02-08 Isis Pharmaceuticals, Inc. Conjugates for use in hepatocyte free uptake assays
US20090069263A1 (en) * 2005-12-16 2009-03-12 Damha Masad J 4'-thioarabinonucleotide-containing oligonucleotides, compounds and methods for their preparation and uses thereof
DK1984382T3 (da) * 2006-01-27 2012-09-03 Santaris Pharma As LNA modificerede fosforthiolerede oligonukleotider
WO2007107162A2 (en) 2006-03-23 2007-09-27 Santaris Pharma A/S Small internally segmented interfering rna
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WO2004083430A2 (en) 2004-09-30
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ES2332178T3 (es) 2010-01-28
US9297010B2 (en) 2016-03-29
JP2006520760A (ja) 2006-09-14
ES2576677T3 (es) 2016-07-08
EP1606406A2 (en) 2005-12-21
ES2332178T5 (es) 2014-02-04
US20070191294A1 (en) 2007-08-16
US8653252B2 (en) 2014-02-18
EP2141234A1 (en) 2010-01-06
ATE443765T1 (de) 2009-10-15
EP1606406B1 (en) 2009-09-23
WO2004083430A3 (en) 2004-11-11
EP2141234B1 (en) 2016-04-27
CA2519860A1 (en) 2004-09-30
US9738894B2 (en) 2017-08-22
DE602004023279D1 (de) 2009-11-05
EP1606406B2 (en) 2013-11-27
DK1606406T4 (da) 2013-12-16
JP4755972B2 (ja) 2011-08-24
AU2004221760A1 (en) 2004-09-30
AU2004221760B2 (en) 2010-03-18
DK2141234T3 (da) 2016-06-20

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