DK1628640T3 - Fremstilling af mikrokapsler ved coacervering, hvilke mikrokapsler indeholder et farmaceutisk middel der er inkorporeret i ethylcelluloseovertrækket - Google Patents
Fremstilling af mikrokapsler ved coacervering, hvilke mikrokapsler indeholder et farmaceutisk middel der er inkorporeret i ethylcelluloseovertrækketInfo
- Publication number
- DK1628640T3 DK1628640T3 DK04741678T DK04741678T DK1628640T3 DK 1628640 T3 DK1628640 T3 DK 1628640T3 DK 04741678 T DK04741678 T DK 04741678T DK 04741678 T DK04741678 T DK 04741678T DK 1628640 T3 DK1628640 T3 DK 1628640T3
- Authority
- DK
- Denmark
- Prior art keywords
- microcapsules
- coacervation
- preparation
- ethyl cellulose
- pharmaceutical agent
- Prior art date
Links
- 239000003094 microcapsule Substances 0.000 title abstract 4
- 238000005354 coacervation Methods 0.000 title abstract 2
- 239000001856 Ethyl cellulose Substances 0.000 title 1
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 title 1
- 239000011248 coating agent Substances 0.000 title 1
- 238000000576 coating method Methods 0.000 title 1
- 229920001249 ethyl cellulose Polymers 0.000 title 1
- 235000019325 ethyl cellulose Nutrition 0.000 title 1
- 239000008177 pharmaceutical agent Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 3
- 239000011247 coating layer Substances 0.000 abstract 1
- 239000010410 layer Substances 0.000 abstract 1
- 230000000873 masking effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000005191 phase separation Methods 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 229920005597 polymer membrane Polymers 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/005—Coating of tablets or the like
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/06—Making microcapsules or microballoons by phase separation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/06—Making microcapsules or microballoons by phase separation
- B01J13/08—Simple coacervation, i.e. addition of highly hydrophilic material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/20—After-treatment of capsule walls, e.g. hardening
- B01J13/206—Hardening; drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT001096A ITMI20031096A1 (it) | 2003-05-30 | 2003-05-30 | Microcapsule per coacervazione contenenti farmaco incorporato nel polimero di rivestimento |
| PCT/EP2004/050962 WO2004105725A2 (en) | 2003-05-30 | 2004-05-28 | Microcapsules by coacervation containing a pharmaceutical incorporated in the coating polymer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1628640T3 true DK1628640T3 (da) | 2008-03-17 |
Family
ID=30131119
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04741678T DK1628640T3 (da) | 2003-05-30 | 2004-05-28 | Fremstilling af mikrokapsler ved coacervering, hvilke mikrokapsler indeholder et farmaceutisk middel der er inkorporeret i ethylcelluloseovertrækket |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20070048385A1 (da) |
| EP (1) | EP1628640B1 (da) |
| JP (1) | JP4968829B2 (da) |
| AT (1) | ATE378041T1 (da) |
| DK (1) | DK1628640T3 (da) |
| ES (1) | ES2297439T3 (da) |
| IT (1) | ITMI20031096A1 (da) |
| PL (1) | PL1628640T3 (da) |
| WO (1) | WO2004105725A2 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101351680B1 (ko) * | 2007-03-22 | 2014-01-15 | 주식회사 엘지생활건강 | 마이크로 캡슐，그 제조방법 및 마이크로 캡슐을 포함하는기능성 조성물 |
| US20160128944A1 (en) | 2013-06-04 | 2016-05-12 | Vyome Biosciences Pvt. Ltd. | Coated particles and compositions comprising same |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4394287A (en) * | 1981-04-10 | 1983-07-19 | Eurand America, Inc. | Incorporation of finely divided additives at the surface of microcapsule walls |
| US4634587A (en) * | 1982-07-09 | 1987-01-06 | Key Pharmaceuticals, Inc. | Sustained release quinidine dosage form |
| US4704285A (en) * | 1985-11-18 | 1987-11-03 | The Dow Chemical Company | Sustained release compositions comprising hydroxypropyl cellulose ethers |
| JPS62135419A (ja) * | 1985-12-06 | 1987-06-18 | Ikeda Mohandou:Kk | ジクロフエナク塩の粒状組成物及びその製造法 |
| JPH0832625B2 (ja) * | 1987-01-29 | 1996-03-29 | 武田薬品工業株式会社 | 有核顆粒およびその製造法 |
| US5026560A (en) * | 1987-01-29 | 1991-06-25 | Takeda Chemical Industries, Ltd. | Spherical granules having core and their production |
| US5252337A (en) * | 1991-06-25 | 1993-10-12 | Eurand America, Inc. | Controlled release calcium channel blocker microcapsules |
| DE69524527D1 (de) * | 1994-10-14 | 2002-01-24 | Japan Energy Corp | AIDS-hemmende Arzneizubereitung und Verfahren |
| DE19539361A1 (de) * | 1995-10-23 | 1997-04-24 | Basf Ag | Verfahren zur Herstellung von mehrschichtigen, festen Arzneiformen zur oralen oder rektalen Verabreichung |
| NZ333514A (en) * | 1996-06-28 | 2000-05-26 | Schering Corp | Oral pharmaceutical composition comprising a triazole antifungal compound |
| FR2758461A1 (fr) * | 1997-01-17 | 1998-07-24 | Pharma Pass | Composition pharmaceutique presentant une biodisponibilite elevee et son procede de preparation |
| UA65607C2 (uk) * | 1998-03-04 | 2004-04-15 | Орто-Макнейл Фармацевтикал, Інк. | Фармацевтична композиція (варіанти) та спосіб її приготування |
| KR20010034770A (ko) * | 1998-04-17 | 2001-04-25 | 우에하라 아끼라 | 멀티플 유닛 타입 서방성 정제 |
| DE19930795A1 (de) * | 1999-07-03 | 2001-01-11 | Encapbiosystems Ag Schiers | Verfahren zur Verkapselung von Substanzen sowie Teilchen dafür |
-
2003
- 2003-05-30 IT IT001096A patent/ITMI20031096A1/it unknown
-
2004
- 2004-05-28 ES ES04741678T patent/ES2297439T3/es not_active Expired - Lifetime
- 2004-05-28 EP EP04741678A patent/EP1628640B1/en not_active Expired - Lifetime
- 2004-05-28 AT AT04741678T patent/ATE378041T1/de not_active IP Right Cessation
- 2004-05-28 DK DK04741678T patent/DK1628640T3/da active
- 2004-05-28 JP JP2006530223A patent/JP4968829B2/ja not_active Expired - Fee Related
- 2004-05-28 PL PL04741678T patent/PL1628640T3/pl unknown
- 2004-05-28 US US10/558,948 patent/US20070048385A1/en not_active Abandoned
- 2004-05-28 WO PCT/EP2004/050962 patent/WO2004105725A2/en not_active Ceased
-
2012
- 2012-11-20 US US13/681,727 patent/US20130156934A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20070048385A1 (en) | 2007-03-01 |
| ITMI20031096A1 (it) | 2004-11-30 |
| EP1628640B1 (en) | 2007-11-14 |
| ES2297439T3 (es) | 2008-05-01 |
| JP4968829B2 (ja) | 2012-07-04 |
| EP1628640A2 (en) | 2006-03-01 |
| WO2004105725A2 (en) | 2004-12-09 |
| ITMI20031096A0 (it) | 2003-05-30 |
| WO2004105725A3 (en) | 2005-05-26 |
| PL1628640T3 (pl) | 2008-06-30 |
| JP2007509844A (ja) | 2007-04-19 |
| ATE378041T1 (de) | 2007-11-15 |
| US20130156934A1 (en) | 2013-06-20 |
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