DK164161C - Kondenserede benzazepiner, fremgangsmaade til fremstilling deraf, farmaceutiske praeparater indeholdende forbindelserne, fremgangsmaade til fremstilling af saadanne praeparater samt anvendelse af forbindelserne til fremstilling af farmaceutiske praeparater - Google Patents

Kondenserede benzazepiner, fremgangsmaade til fremstilling deraf, farmaceutiske praeparater indeholdende forbindelserne, fremgangsmaade til fremstilling af saadanne praeparater samt anvendelse af forbindelserne til fremstilling af farmaceutiske praeparater

Info

Publication number: DK164161C
Authority: DK; Denmark
Prior art keywords: preparations; procedures; benzazepines; condensed; preparing
Prior art date: 1986-01-16

Application number

DK479087A

Other languages

Danish (da)

English (en)

Other versions

DK479087A (da

DK479087D0 (da

DK164161B (da

Inventor

Joel Gilbert Berger

Wei Kong Chang

Elijah Herman Gold

John Welch Clader

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-01-16

Filing date

1987-09-14

Publication date

1992-10-26

1987-09-14 Application filed by Schering Corp filed Critical Schering Corp

1987-09-14 Publication of DK479087A publication Critical patent/DK479087A/da

1987-09-14 Publication of DK479087D0 publication Critical patent/DK479087D0/da

1992-05-18 Publication of DK164161B publication Critical patent/DK164161B/da

1992-10-26 Application granted granted Critical

1992-10-26 Publication of DK164161C publication Critical patent/DK164161C/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DK479087A 1986-01-16 1987-09-14 Kondenserede benzazepiner, fremgangsmaade til fremstilling deraf, farmaceutiske praeparater indeholdende forbindelserne, fremgangsmaade til fremstilling af saadanne praeparater samt anvendelse af forbindelserne til fremstilling af farmaceutiske praeparater DK164161C (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US82047186A	1986-01-16	1986-01-16
US82047186		1986-01-16
US8700042		1987-01-14
PCT/US1987/000042 WO1987004430A2 (en)	1986-01-16	1987-01-14	Fused benzazepines

Publications (4)

Publication Number	Publication Date
DK479087A DK479087A (da)	1987-09-14
DK479087D0 DK479087D0 (da)	1987-09-14
DK164161B DK164161B (da)	1992-05-18
DK164161C true DK164161C (da)	1992-10-26

Family

ID=25230864

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK479087A DK164161C (da)	1986-01-16	1987-09-14	Kondenserede benzazepiner, fremgangsmaade til fremstilling deraf, farmaceutiske praeparater indeholdende forbindelserne, fremgangsmaade til fremstilling af saadanne praeparater samt anvendelse af forbindelserne til fremstilling af farmaceutiske praeparater

Country Status (19)

Country	Link
EP (2)	EP0254737B1 (cs)
JP (1)	JPH0681745B2 (cs)
KR (1)	KR900007781B1 (cs)
AU (1)	AU588080B2 (cs)
CA (1)	CA1333485C (cs)
CS (1)	CS414091A3 (cs)
DK (1)	DK164161C (cs)
ES (1)	ES2031834T3 (cs)
FI (1)	FI83512C (cs)
GR (1)	GR3000994T3 (cs)
HU (1)	HU199805B (cs)
IE (1)	IE59651B1 (cs)
IL (2)	IL81268A0 (cs)
NZ (1)	NZ218953A (cs)
OA (1)	OA08660A (cs)
PT (1)	PT84109B (cs)
SG (1)	SG128692G (cs)
WO (1)	WO1987004430A2 (cs)
ZA (1)	ZA87291B (cs)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4973586A (en) *	1986-01-16	1990-11-27	Schering Corporation	Fused benzazepines, compositions of, and medical use thereof
JPH0678317B2 (ja) *	1987-07-15	1994-10-05	シェリング・コーポレーション	縮合ベンズアゼピン
DK325188D0 (da) *	1988-06-15	1988-06-15	Novo Industri As	Hidtil ukendte benzazepinderivater
HUT58035A (en) *	1988-07-29	1992-01-28	Schering Corp	Process for enanthiospecific synthesis of intermediates of hexahydrobenzo(d)naphtno(2,1-b)azepines
US5091526A (en) *	1988-07-29	1992-02-25	Schering Corporation	Process for the enantiospecific synthesis of intermediates for hexahydro-benzo[d]-naphtho[2,1-b]azepines
US5104814A (en) *	1988-11-22	1992-04-14	Schering Corporation	Assay kit and methods for neuroleptic drugs
FR2642065B1 (fr) *	1989-01-24	1991-05-24	Lipha	Derives d'acides benzocycloalcenyl dihydroxy alcanoiques, procede de preparation et medicaments les contenant
EP0513174B1 (en) *	1990-02-02	1995-08-16	Schering Corporation	4,5-cycloalkano-3-benzazepin-7-ol-derivatives and their use
US5461147A (en) *	1993-09-27	1995-10-24	Schering Corporation	Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
US5463051A (en) *	1993-09-27	1995-10-31	Schering Corporation	Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
US5461148A (en) *	1993-09-27	1995-10-24	Schering Corporation	Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
AR027687A1 (es) *	2000-03-22	2003-04-09	Yakult Honsha Kk	Procedimiento para preparar camptotecina
EP2316468A1 (en)	2002-02-22	2011-05-04	Shire LLC	Delivery system and methods for protecting and administering dextroamphetamine
DE60321354D1 (de) *	2002-08-29	2008-07-10	Schering Corp	Selektive d1/d5 rezeptorantagonisten zur behandlung von fettleibigkeit und von zns störungen
WO2005035504A2 (en) *	2003-05-22	2005-04-21	Schering Corporation	5-h -benzo [d] naphth [2, 1-b] azepine derivative as selective d1/d5 receptor antagonists for the treatment of obesity and cns disorders
EP2164324B1 (en) *	2007-06-15	2014-08-13	University Of Florida Research Foundation	Therapeutic compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3393192A (en) *	1965-04-26	1968-07-16	Schering Corp	Novel benzazepines
GB1118688A (en)	1967-02-17	1968-07-03	Scherico Ltd	Novel benzazepines and process for making same
CH481110A (de) *	1967-02-17	1969-11-15	Geigy Ag J R	Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
US3609138A (en)	1967-12-22	1971-09-28	Ciba Geigy Corp	1-aryl-3-benzazepines
NL7206204A (cs) *	1971-05-10	1972-11-14
US3939165A (en) *	1974-11-14	1976-02-17	Morton-Norwich Products, Inc.	5,6,6A,6B,7,8-Hexahydrobenz[a]phenanthridine hydrochloride
US4011319A (en)	1975-07-02	1977-03-08	Smithkline Corporation	Pharmaceutical compositions and methods involving benzazepine derivatives
US4284555A (en)	1979-04-27	1981-08-18	Schering Corporation	7-Chloro-8(substituted amino carbonyloxy)-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4477378A (en)	1980-02-05	1984-10-16	Schering Corp.	Esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines

1987
- 1987-01-14 AU AU68920/87A patent/AU588080B2/en not_active Ceased
- 1987-01-14 HU HU87914A patent/HU199805B/hu not_active IP Right Cessation
- 1987-01-14 WO PCT/US1987/000042 patent/WO1987004430A2/en not_active Ceased
- 1987-01-14 JP JP62500944A patent/JPH0681745B2/ja not_active Expired - Lifetime
- 1987-01-14 EP EP87900939A patent/EP0254737B1/en not_active Expired - Lifetime
- 1987-01-14 KR KR1019870700836A patent/KR900007781B1/ko not_active Expired
- 1987-01-15 ZA ZA87291A patent/ZA87291B/xx unknown
- 1987-01-15 IL IL81268A patent/IL81268A0/xx not_active IP Right Cessation
- 1987-01-15 EP EP87100446A patent/EP0230270B1/en not_active Expired - Lifetime
- 1987-01-15 ES ES198787100446T patent/ES2031834T3/es not_active Expired - Lifetime
- 1987-01-15 PT PT84109A patent/PT84109B/pt not_active IP Right Cessation
- 1987-01-15 CA CA000527422A patent/CA1333485C/en not_active Expired - Fee Related
- 1987-01-15 NZ NZ218953A patent/NZ218953A/xx unknown
- 1987-01-15 IL IL103007A patent/IL103007A/xx not_active IP Right Cessation
- 1987-01-20 IE IE11287A patent/IE59651B1/en not_active IP Right Cessation
- 1987-09-14 DK DK479087A patent/DK164161C/da not_active IP Right Cessation
- 1987-09-15 OA OA59194A patent/OA08660A/xx unknown
- 1987-09-15 FI FI874006A patent/FI83512C/fi not_active IP Right Cessation
1990
- 1990-10-29 GR GR90400833T patent/GR3000994T3/el unknown
1991
- 1991-12-30 CS CS914140A patent/CS414091A3/cs unknown
1992
- 1992-12-17 SG SG1286/92A patent/SG128692G/en unknown

Also Published As

Publication number	Publication date
IE870112L (en)	1987-07-16
IL81268A0 (en)	1987-08-31
ZA87291B (en)	1987-11-25
NZ218953A (en)	1990-03-27
HUT48600A (en)	1989-06-28
EP0230270B1 (en)	1990-08-01
PT84109B (pt)	1989-07-31
SG128692G (en)	1993-03-12
AU6892087A (en)	1987-08-14
GR3000994T3 (en)	1991-12-10
DK479087A (da)	1987-09-14
FI83512B (fi)	1991-04-15
DK479087D0 (da)	1987-09-14
AU588080B2 (en)	1989-09-07
FI874006A0 (fi)	1987-09-15
WO1987004430A3 (en)	1988-03-24
WO1987004430A2 (en)	1987-07-30
EP0254737A1 (en)	1988-02-03
EP0254737B1 (en)	1990-07-25
ES2031834T3 (es)	1993-01-01
KR900007781B1 (ko)	1990-10-20
PT84109A (en)	1987-02-01
JPH0681745B2 (ja)	1994-10-19
IL103007A (en)	1993-07-08
FI874006L (fi)	1987-09-15
CA1333485C (en)	1994-12-13
HU199805B (en)	1990-03-28
JPS63502348A (ja)	1988-09-08
CS414091A3 (en)	1992-05-13
EP0230270A2 (en)	1987-07-29
EP0230270A3 (en)	1987-10-21
KR880700794A (ko)	1988-04-12
IE59651B1 (en)	1994-03-09
OA08660A (en)	1988-11-30
FI83512C (fi)	1991-07-25
DK164161B (da)	1992-05-18

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DK365087A (da)	1988-01-16	1,3,5-trithianderivater, fremgangsmaade til fremstilling af saadanne forbindelser og laegemiddel indeholdende disse

Legal Events

Date	Code	Title	Description
1996-09-16	PBP	Patent lapsed