DK165167C - Farmaceutisk middel med metabolisk og energetisk virkning indeholdende coenzym q10 og carnitin eller acetylcarnitin - Google Patents

Farmaceutisk middel med metabolisk og energetisk virkning indeholdende coenzym q10 og carnitin eller acetylcarnitin

Info

Publication number: DK165167C
Authority: DK; Denmark
Prior art keywords: carnitin; coenzym; metabolic; acetyl; pharmaceutical substance
Prior art date: 1983-02-16

Application number

DK072284A

Other languages

Danish (da)

English (en)

Other versions

DK72284D0 (da

DK72284A (da

DK165167B (da

Inventor

Alberto Bertelli

Original Assignee

Sigma Tau Ind Farmaceuti

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-02-16

Filing date

1984-02-16

Publication date

1993-03-01

1984-02-16 Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti

1984-02-16 Publication of DK72284D0 publication Critical patent/DK72284D0/da

1984-08-17 Publication of DK72284A publication Critical patent/DK72284A/da

1992-10-19 Publication of DK165167B publication Critical patent/DK165167B/da

1993-03-01 Application granted granted Critical

1993-03-01 Publication of DK165167C publication Critical patent/DK165167C/da

Links

PHIQHXFUZVPYII-LURJTMIESA-O (S)-carnitinium Chemical compound C[N+](C)(C)C[C@@H](O)CC(O)=O PHIQHXFUZVPYII-LURJTMIESA-O 0.000 title 2
125000002777 acetyl group Chemical class [H]C([H])([H])C(*)=O 0.000 title 1
239000003814 drug Substances 0.000 title 1
230000000694 effects Effects 0.000 title 1
230000002503 metabolic effect Effects 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Epidemiology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

DK072284A 1983-02-16 1984-02-16 Farmaceutisk middel med metabolisk og energetisk virkning indeholdende coenzym q10 og carnitin eller acetylcarnitin DK165167C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CH85883		1983-02-16
CH858/83A CH655005A5 (it)	1983-02-16	1983-02-16	Composizione farmaceutica ad azione metabolica ed energetica utilizzabile in terapia cardiaca e vascolare.

Publications (4)

Publication Number	Publication Date
DK72284D0 DK72284D0 (da)	1984-02-16
DK72284A DK72284A (da)	1984-08-17
DK165167B DK165167B (da)	1992-10-19
DK165167C true DK165167C (da)	1993-03-01

Family

ID=4196830

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK072284A DK165167C (da)	1983-02-16	1984-02-16	Farmaceutisk middel med metabolisk og energetisk virkning indeholdende coenzym q10 og carnitin eller acetylcarnitin

Country Status (11)

Country	Link
US (1)	US4599232A (th)
JP (1)	JPS59186914A (th)
BE (1)	BE898918A (th)
CH (1)	CH655005A5 (th)
DE (1)	DE3405581A1 (th)
DK (1)	DK165167C (th)
FR (1)	FR2543827B1 (th)
GB (1)	GB2137088B (th)
IT (1)	IT1170235B (th)
NL (1)	NL192778C (th)
SE (1)	SE457143B (th)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1209519B (it) *	1984-04-10	1989-08-30	Poli Ind Chimica Spa	Composti ad attivita'cardiotrofica.
CH662505A5 (it) *	1985-04-30	1987-10-15	Seuref Ag	Composizioni farmaceutiche ad azione protettiva vascolare.
CH670763A5 (th) *	1985-08-02	1989-07-14	Seuref Ag
CH666183A5 (it) *	1985-08-06	1988-07-15	Seuref Ag	Composizione farmaceutica ad azione protettiva cardiaca e metabolica sul metabolismo energetico muscolare.
IT1184655B (it) *	1985-10-14	1987-10-28	Sigma Tau Ind Farmaceuti	Imiego di acetil l-carnitina nel trattamento terapeutico degli stati di shock
SE8703321D0 (sv) *	1987-08-27	1987-08-27	Sockerbolaget Ab	Kostforsterkning
JPH02188523A (ja) *	1989-01-13	1990-07-24	M S C:Kk	睡眠時無呼吸症治療薬
GB8907276D0 (en) *	1989-03-31	1989-05-17	Therapy Advisory Services Limi	Health supplement
AT393954B (de) *	1990-02-28	1992-01-10	Bock Orthopaed Ind	Verfahren und vorrichtung zur bestimmung von gebrauchseigenschaften eines prothesenschaftes
IT1254314B (it) *	1992-03-27	1995-09-14	Sigma Tau Ind Farmaceuti	Composizioni farmaceutiche conyenenti l-carnitina e acil- carnitine inassociazione con ace-inibitori per il trattamento di patologie cardiovascolari.
US5981601A (en) *	1992-05-28	1999-11-09	Centre For Molecular Biology And Medicine	Method for enhancing cellular bioenergy
DE4335454A1 (de) *	1993-10-19	1995-04-20	Schleicher Peter	Geriatrikum
US5707971A (en) *	1995-06-07	1998-01-13	Life Resuscitation Technologies, Inc.	Modulation of glycolytic ATP production
US6080788A (en) *	1997-03-27	2000-06-27	Sole; Michael J.	Composition for improvement of cellular nutrition and mitochondrial energetics
BR9808088A (pt) *	1997-03-27	2000-03-08	Michael J Sole	Suplemento nutricional, uso do mesmo e métodos de tratamento de um sistema orgânico crìtico e de insuficiência cardìaca congestiva
IT1291127B1 (it) *	1997-04-01	1998-12-29	Sigma Tau Ind Farmaceuti	Integratore alimentare per soggetti dediti ad intensa e prolungata attivita' fisica
US5973004A (en) *	1997-04-04	1999-10-26	Howard; James R.	L-carnitine, acetyl-L-carnitine, and pantothenic acid or ubiquinone, combined for prevention and treatment of syndromes related to ineffective energy metabolism
US5889055A (en) *	1997-04-04	1999-03-30	Howard; James R.	L-carnitine and acetyl-L-carnitine combined for prevention and treatment of syndromes related to diseases of energy metabolism
US5916912A (en) *	1997-06-16	1999-06-29	The Regents Of The University Of California	Dietary composition for enhancing metabolism and alleviating oxidative stress
US7371415B1 (en)	1998-04-03	2008-05-13	The Daily Wellness Company	Method and composition for improving sexual fitness
US20050196470A9 (en) *	1998-04-03	2005-09-08	Wuh Hank C	Method and composition for enhancing sexual desire
WO1999051252A1 (en)	1998-04-03	1999-10-14	The Daily Wellness Company	Compositions comprising l-arginine, ginseng and gingko biloba for enhancing blood circulation
IT1299266B1 (it)	1998-05-15	2000-02-29	Sigma Tau Ind Farmaceuti	Inibitori reversibili della carnitina palmitoil trasferasi
US6616942B1 (en)	1999-03-29	2003-09-09	Soft Gel Technologies, Inc.	Coenzyme Q10 formulation and process methodology for soft gel capsules manufacturing
US20070072927A1 (en) *	1999-09-23	2007-03-29	Vita Joseph A	Nutritional supplement for increased energy and stamina
WO2001021208A1 (en)	1999-09-23	2001-03-29	Juvenon Corporation	Nutritional supplement for increased energy and stamina
US6562869B1 (en)	1999-09-23	2003-05-13	Juvenon, Inc.	Nutritional supplement for increased energy and stamina
CA2389623A1 (en)	1999-11-03	2001-05-10	Juvenon, Inc.	Method of treating benign forgetfulness
US8753675B1 (en)	2000-01-20	2014-06-17	Raj K. Chopra	Reduced form of Coenzyme Q in high bioavailability stable dosage forms and related applications
US6740338B1 (en)	2000-01-20	2004-05-25	Raj K. Chopra	Reduced form of Cenzyme Q in high bioavailability stable oral dosage form
CA2399319A1 (en) *	2000-01-25	2001-08-16	Nathan D. Hamilton	Nutritional supplements for aged pets
DE10036798A1 (de) *	2000-07-28	2002-02-07	Beiersdorf Ag	Mittel zur Behandlung der Haare und der Kopfhaut
US6441050B1 (en)	2000-08-29	2002-08-27	Raj K. Chopra	Palatable oral coenzyme Q liquid
US6989164B2 (en)	2000-12-22	2006-01-24	The Daily Wellness Company	Method and composition for improving male fertility health
US6497885B2 (en)	2000-12-22	2002-12-24	The Daily Wellness Company	Method and composition for improving fertility health in female and male animals and humans
US20040043013A1 (en)	2000-12-28	2004-03-04	Mccleary Edward Larry	Metabolic uncoupling therapy
US20060062864A1 (en) *	2000-12-28	2006-03-23	Mccleary Edward L	Weight loss composition and method
US6579866B2 (en)	2000-12-28	2003-06-17	Mccleary Larry	Composition and method for modulating nutrient partitioning
KR20060103288A (ko) *	2001-05-10	2006-09-28	카네카 코포레이션	활성 성분으로 조효소 ｑ를 함유하는 경점막 투여용 조성물
EP1407782A4 (en) *	2001-06-28	2004-10-20	Takeda Chemical Industries Ltd	AGENTS FOR PREVENTION / TREATMENT OF FUNCTIONAL ORGANIC DISEASES AND ORGANIC DYSFUNCTION
US8703209B2 (en) *	2003-06-17	2014-04-22	Edward Larry McCleary	Composition and method for modulating hydrogen ion physiology
EP1875816A3 (en) *	2003-07-10	2008-03-12	Carl A. Forest	Beverages with specialized supplements
US20080089877A1 (en) *	2003-08-14	2008-04-17	Udell Ronald G	Super Absorption Coenzyme Q10
US7169385B2 (en) *	2003-09-29	2007-01-30	Ronald G. Udell	Solubilized CoQ-10 and carnitine
US8124072B2 (en) *	2003-09-29	2012-02-28	Soft Gel Technologies, Inc.	Solubilized CoQ-10
WO2005032278A1 (en)	2003-09-29	2005-04-14	Soft Gel Technologies, Inc.	SOLUBILIZED CoQ-10
US20050232911A1 (en) *	2004-04-19	2005-10-20	Schreiber Brian D	Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid
CN101022793B (zh) *	2004-06-29	2011-05-11	美国益力斯林公司	用以促进新陈代谢和降低活性氧水平的食品组合物
EP1888059B1 (en) *	2005-06-01	2014-12-17	Edison Pharmaceuticals, Inc.	Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers
US20050249803A1 (en) *	2005-06-03	2005-11-10	Udell Ronald G	Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols
US7887852B2 (en) *	2005-06-03	2011-02-15	Soft Gel Technologies, Inc.	Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols
PL1933821T3 (pl) *	2005-09-15	2021-01-11	Ptc Therapeutics, Inc.	Warianty łańcucha końcowego środków terapeutycznych o aktywności redoks do leczenia chorób mitochondrialnych i innych stanów oraz do modulacji biomarkerów energetycznych
US20100022629A1 (en) *	2006-01-13	2010-01-28	Elixirin	Dietary Methods and Compositions for Enhancing Metabolism and Reducing Reactive Oxygen Species
JP5374162B2 (ja)	2006-02-22	2013-12-25	エジソンファーマシューティカルズ，インコーポレイテッド	ミトコンドリア病および他の症状の処置のためのレドックス活性化治療の側鎖変異体およびエネルギーバイオマーカーの調節
US20080020022A1 (en) *	2006-06-05	2008-01-24	Udell Ronald G	Chewable co-enzyme q-10 capsule
JP2009037201A (ja) *	2007-03-14	2009-02-19	Fujifilm Corp	感光性樹脂組成物、それを用いた硬化レリーフパターンの製造方法及び半導体装置
US8343541B2 (en)	2007-03-15	2013-01-01	Soft Gel Technologies, Inc.	Ubiquinol and alpha lipoic acid compositions
ES2306610B1 (es) *	2007-04-16	2009-09-11	Universidad De Sevilla	Uso de la l-carnitina para el tratamiento de la hipertension arterial.
TW200916090A (en) *	2007-06-22	2009-04-16	Kaneka Corp	Composition comprising coenzyme Q10
WO2009001786A1 (ja) *	2007-06-22	2008-12-31	Kaneka Corporation	生理活性物質含有組成物
JP5364580B2 (ja) *	2007-08-22	2013-12-11	株式会社カネカ	還元型補酵素ｑ１０の製造方法、ならびに、その安定化方法
CN101951930A (zh) *	2008-02-19	2011-01-19	阿奈斯特药品株式会社	对身体功能的恢复有用的口服或经肠组合物
LT3827815T (lt)	2008-09-10	2023-10-10	Ptc Therapeutics, Inc.	Psichologinių raidos sutrikimų gydymas oksidacijos redukcijos atžvilgiu aktyviais vaistais
JP6905527B2 (ja)	2015-12-17	2021-07-21	ピーティーシーセラピューティクス，インコーポレイテッド	酸化ストレス障害を処置するためのフルオロアルキル、フルオロアルコキシ、フェノキシ、ヘテロアリールオキシ、アルコキシ、およびアミノ１，４−ベンゾキノン誘導体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2903558C2 (de) *	1978-02-03	1994-09-01	Sigma Tau Ind Farmaceuti	Verwendung von L-Carnitin
US4346107A (en) *	1979-02-12	1982-08-24	Claudio Cavazza	Pharmaceutical composition comprising acyl-carnitine for the treatment of impaired cerebral metabolism
IT1206954B (it) *	1979-02-12	1989-05-17	Sigma Tau Ind Farmaceuti	Agenti terapeutici a base di un acil derivato della carnitina per la cura di vasculopatie periferiche
IT1142934B (it) *	1981-11-06	1986-10-15	Sigma Tau Ind Farmaceuti	Uso della carnitina e delle acilcarnitine inferiori nel trattamento terapeutico della patologia delle vene

1983
- 1983-02-16 CH CH858/83A patent/CH655005A5/it not_active IP Right Cessation
- 1983-10-31 IT IT23559/83A patent/IT1170235B/it active
1984
- 1984-02-09 US US06/578,588 patent/US4599232A/en not_active Expired - Lifetime
- 1984-02-13 GB GB08403668A patent/GB2137088B/en not_active Expired
- 1984-02-15 NL NL8400488A patent/NL192778C/nl not_active IP Right Cessation
- 1984-02-16 DE DE19843405581 patent/DE3405581A1/de active Granted
- 1984-02-16 JP JP59026179A patent/JPS59186914A/ja active Granted
- 1984-02-16 SE SE8400851A patent/SE457143B/sv not_active IP Right Cessation
- 1984-02-16 FR FR8402347A patent/FR2543827B1/fr not_active Expired
- 1984-02-16 DK DK072284A patent/DK165167C/da not_active IP Right Cessation
- 1984-02-16 BE BE2/60334A patent/BE898918A/nl not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK72284D0 (da)	1984-02-16
JPS59186914A (ja)	1984-10-23
IT8323559A0 (it)	1983-10-31
US4599232A (en)	1986-07-08
NL8400488A (nl)	1984-09-17
SE8400851D0 (sv)	1984-02-16
JPH027572B2 (th)	1990-02-19
DK72284A (da)	1984-08-17
DE3405581C2 (th)	1992-10-22
DK165167B (da)	1992-10-19
FR2543827A1 (fr)	1984-10-12
NL192778C (nl)	1998-02-03
GB2137088A (en)	1984-10-03
IT1170235B (it)	1987-06-03
GB8403668D0 (en)	1984-03-14
FR2543827B1 (fr)	1987-06-12
NL192778B (nl)	1997-10-01
BE898918A (nl)	1984-08-16
SE8400851L (sv)	1984-08-17
CH655005A5 (it)	1986-03-27
GB2137088B (en)	1986-02-05
DE3405581A1 (de)	1984-10-18
SE457143B (sv)	1988-12-05

Legal Events

Date	Code	Title	Description
1986-03-03	AHB	Application shelved due to non-payment
2004-03-08	PUP	Patent expired

Publication	Publication Date	Title
DK165167C (da)	1993-03-01	Farmaceutisk middel med metabolisk og energetisk virkning indeholdende coenzym q10 og carnitin eller acetylcarnitin
AU5893886A (en)	1987-01-29	Digital computer with cache for parallel processors
DK305587A (da)	1987-12-18	Beholder med skruelaag og garantilukke
DK1790A (da)	1990-01-04	Laegemidler indeholdende insulinderivater
DK390586A (da)	1987-02-17	Laegemiddelpartikler med konstant frigoerelseshastighed og umiddelbar absorption
DK17885D0 (da)	1985-01-14	Antiviralt middel
ZA862640B (en)	1987-02-25	Vinylidene chloride composition and film made therefrom
DK162986A (da)	1986-10-13	Terapeutisk middel i enhedsdosisform
KR860005845A (ko)	1986-08-13	이축 연신 폴리에스테르 필름
DK484285A (da)	1986-04-24	Forbindelser med herbicid, insekticid, acaricid eller fungicid virkning, midler indeholdende disse forbindelser og deres anvendelse
DE3219240A1 (de)	1982-12-09	Biaxial orientierte polyesterfolie
EP0199290A3 (en)	1988-08-03	Silver halide photographic emulsion and photographic material containing the same
MX153252A (es)	1986-09-02	Mejoras en anillo de sujecion para tornillos y similares
DK139286D0 (da)	1986-03-25	Inden- og naphthalenderivater
BR8606217A (pt)	1987-09-29	Polimetilsiloxano e composicao contendo o dito polimetilsiloxano e composicao curavel
IT8567259A0 (it)	1985-03-15	Boccola con ralla reggispinta e procedimento per la sua fabbricazione
DK255586A (da)	1986-12-01	Sammensat folie
BR8403513A (pt)	1985-06-25	Navio possuindo uma configuracao em secao geralmente quadrangular
DK0478681T3 (da)	1993-11-29	Forbedringer ved eller i forbindelse med røntgenfilmkassetter
GB8604748D0 (en)	1986-04-03	Drying photographic film
DK90086D0 (da)	1986-02-27	3-aryloxyazetidincarboxamider samt middel med indhold heraf
DK164867C (da)	1993-11-08	Pyrimidooe4,5-gaaquinolin-derivater eller salte deraf og farmaceutiske formuleringer indeholdende disse
DK321789D0 (da)	1989-06-28	Anvendelse af ajoen og ajoenderivater som eller i cytostatika og/eller cytotoksika samt middel indeholdende disse forbindelser
DK550089A (da)	1990-05-05	Indretning til propel eller skrue
AU1852888A (en)	1989-01-05	Improvements relating to the treatment of medium used in photographic processors