DK165684A - (1h-tetrazol-5-yl)-2(1h)-quinolinoner - Google Patents
(1h-tetrazol-5-yl)-2(1h)-quinolinoner Download PDFInfo
- Publication number
- DK165684A DK165684A DK165684A DK165684A DK165684A DK 165684 A DK165684 A DK 165684A DK 165684 A DK165684 A DK 165684A DK 165684 A DK165684 A DK 165684A DK 165684 A DK165684 A DK 165684A
- Authority
- DK
- Denmark
- Prior art keywords
- tetrazol
- quinolinones
- quinolinone
- cyano
- compounds
- Prior art date
Links
- WPZVLGZVNGNCJN-UHFFFAOYSA-N 1-(2h-tetrazol-5-yl)quinolin-2-one Chemical class O=C1C=CC2=CC=CC=C2N1C1=NN=NN1 WPZVLGZVNGNCJN-UHFFFAOYSA-N 0.000 title abstract 2
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 abstract 2
- PXIPVTKHYLBLMZ-UHFFFAOYSA-N Sodium azide Chemical compound [Na+].[N-]=[N+]=[N-] PXIPVTKHYLBLMZ-UHFFFAOYSA-N 0.000 abstract 2
- WNRMLIGSXULUPQ-UHFFFAOYSA-N 2-oxo-1h-quinoline-3-carbonitrile Chemical compound C1=CC=C2C=C(C#N)C(=O)NC2=C1 WNRMLIGSXULUPQ-UHFFFAOYSA-N 0.000 abstract 1
- 235000019270 ammonium chloride Nutrition 0.000 abstract 1
- 239000000043 antiallergic agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Laminated Bodies (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47896583 | 1983-03-25 | ||
| US06/478,965 US4735948A (en) | 1983-03-25 | 1983-03-25 | (1H-tetrazol-5-yl)-2(1H)-quinolinones and-naphthyridones and antiallergic use thereof |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK165684D0 DK165684D0 (da) | 1984-03-23 |
| DK165684A true DK165684A (da) | 1984-09-26 |
| DK163238B DK163238B (da) | 1992-02-10 |
| DK163238C DK163238C (da) | 1992-06-29 |
Family
ID=23902120
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK165684A DK163238C (da) | 1983-03-25 | 1984-03-23 | 3-(1h-tetrazol-5-yl)-2(1h)-quinolinon samt farmaceutisk acceptable salte deraf og fremgangsmaade til fremstilling af disse forbindelser |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4735948A (da) |
| EP (1) | EP0120483B1 (da) |
| JP (1) | JPS59176276A (da) |
| KR (1) | KR900003650B1 (da) |
| AT (1) | ATE26276T1 (da) |
| AU (1) | AU562115B2 (da) |
| CA (1) | CA1241001A (da) |
| DE (1) | DE3462895D1 (da) |
| DK (1) | DK163238C (da) |
| ES (1) | ES530877A0 (da) |
| GR (1) | GR81908B (da) |
| IE (1) | IE57073B1 (da) |
| IL (1) | IL71319A (da) |
| NO (1) | NO841157L (da) |
| NZ (1) | NZ207581A (da) |
| PT (1) | PT78289B (da) |
| ZA (1) | ZA842065B (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT79031B (en) * | 1983-08-20 | 1986-08-22 | Boots Co Plc | Therapeutic agents |
| US5358949A (en) * | 1986-03-05 | 1994-10-25 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives |
| US4916131A (en) * | 1986-10-15 | 1990-04-10 | Schering Corporation | Naphthyridine derivatives and method for treating allergic reactions |
| EP0267691A3 (en) * | 1986-10-15 | 1989-08-23 | Schering Corporation | Use of 1-substituted naphthyridine and pyridopyrazine derivatives for the preparation of medicaments with immunosuppressor activity. |
| US5037826A (en) * | 1986-10-15 | 1991-08-06 | Schering Corporation | 1-substituted naphthyridine and pyridopyrazine derivatives |
| US5064837A (en) * | 1989-11-13 | 1991-11-12 | Schering Corporation | 3-substituted-1-aryl-2(h)-quinolones and their pharmaceutical compositions |
| GB9026389D0 (en) * | 1990-12-05 | 1991-01-23 | Merck Sharp & Dohme | Therapeutic agents |
| GB9125485D0 (en) * | 1991-11-29 | 1992-01-29 | Merck Sharp & Dohme | Therapeutic agents |
| WO1994012499A1 (fr) * | 1992-12-01 | 1994-06-09 | The Green Cross Corporation | Derive de 1,8-naphthyridin-2-one et utilisation de ce derive |
| DE19727410A1 (de) * | 1997-06-27 | 1999-01-07 | Hoechst Schering Agrevo Gmbh | 3-(5-Tetrazolylcarbonyl)-2-chinolone und diese enthaltende nutzpflanzenschützende Mittel |
| GB0316546D0 (en) | 2003-07-15 | 2003-08-20 | Novartis Ag | Process for the manufacture of organic compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1444369A (en) * | 1973-04-05 | 1976-07-28 | Allen & Hanburys Ltd | 1,8-naphthyridines |
| US3993656A (en) * | 1974-11-19 | 1976-11-23 | Merck & Co., Inc. | 1,8-Naphthyridine compounds |
| US4035368A (en) * | 1975-04-02 | 1977-07-12 | Riker Laboratories, Inc. | Substituted 3-(1H-tetrazol-5-yl)-quinoline compounds |
| US4350817A (en) * | 1980-02-28 | 1982-09-21 | American Home Products Corporation | 4-Cl, Br or I-3-Carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives |
| NZ212209A (en) * | 1984-05-29 | 1988-08-30 | Pfizer | Quinolone derivatives and pharmaceutical compositions |
-
1983
- 1983-03-25 US US06/478,965 patent/US4735948A/en not_active Expired - Lifetime
-
1984
- 1984-03-20 ZA ZA842065A patent/ZA842065B/xx unknown
- 1984-03-20 CA CA000449959A patent/CA1241001A/en not_active Expired
- 1984-03-21 GR GR74164A patent/GR81908B/el unknown
- 1984-03-21 NZ NZ207581A patent/NZ207581A/en unknown
- 1984-03-21 PT PT78289A patent/PT78289B/pt not_active IP Right Cessation
- 1984-03-21 AU AU25952/84A patent/AU562115B2/en not_active Ceased
- 1984-03-22 ES ES530877A patent/ES530877A0/es active Granted
- 1984-03-22 JP JP59053691A patent/JPS59176276A/ja active Granted
- 1984-03-22 IL IL71319A patent/IL71319A/xx unknown
- 1984-03-23 DE DE8484103231T patent/DE3462895D1/de not_active Expired
- 1984-03-23 EP EP84103231A patent/EP0120483B1/en not_active Expired
- 1984-03-23 NO NO841157A patent/NO841157L/no unknown
- 1984-03-23 IE IE720/84A patent/IE57073B1/en not_active IP Right Cessation
- 1984-03-23 AT AT84103231T patent/ATE26276T1/de active
- 1984-03-23 DK DK165684A patent/DK163238C/da not_active IP Right Cessation
- 1984-03-24 KR KR1019840001514A patent/KR900003650B1/ko not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS59176276A (ja) | 1984-10-05 |
| IE840720L (en) | 1984-09-25 |
| ES8601963A1 (es) | 1985-11-01 |
| GR81908B (da) | 1984-12-12 |
| CA1241001A (en) | 1988-08-23 |
| DK163238C (da) | 1992-06-29 |
| ZA842065B (en) | 1984-10-31 |
| DE3462895D1 (de) | 1987-05-07 |
| IE57073B1 (en) | 1992-04-22 |
| KR900003650B1 (ko) | 1990-05-28 |
| AU562115B2 (en) | 1987-05-28 |
| IL71319A0 (en) | 1984-06-29 |
| ATE26276T1 (de) | 1987-04-15 |
| PT78289A (en) | 1984-04-01 |
| EP0120483B1 (en) | 1987-04-01 |
| KR840008153A (ko) | 1984-12-13 |
| NO841157L (no) | 1984-09-26 |
| JPH0452273B2 (da) | 1992-08-21 |
| PT78289B (en) | 1986-04-22 |
| EP0120483A1 (en) | 1984-10-03 |
| AU2595284A (en) | 1984-09-27 |
| DK165684D0 (da) | 1984-03-23 |
| ES530877A0 (es) | 1985-11-01 |
| DK163238B (da) | 1992-02-10 |
| IL71319A (en) | 1988-03-31 |
| NZ207581A (en) | 1987-01-23 |
| US4735948A (en) | 1988-04-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed | ||
| PBP | Patent lapsed |