DK1679319T3 - Fremgangsmåde til forebyggelse og behandling af Alzheimers sygdom (AD) - Google Patents

Fremgangsmåde til forebyggelse og behandling af Alzheimers sygdom (AD)

Info

Publication number: DK1679319T3
Authority: DK; Denmark
Prior art keywords: arg; glu; asp; tyr; phe
Prior art date: 2003-01-14

Application number

DK05107898T

Other languages

Danish (da)

English (en)

Inventor

Frank Mattner

Original Assignee

Frank Mattner

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-01-14

Filing date

2004-01-13

Publication date

2008-01-28

2004-01-13 Application filed by Frank Mattner filed Critical Frank Mattner

2008-01-28 Application granted granted Critical

2008-01-28 Publication of DK1679319T3 publication Critical patent/DK1679319T3/da

Links

208000024827 Alzheimer disease Diseases 0.000 title abstract 6
238000000034 method Methods 0.000 title 1
230000002265 prevention Effects 0.000 title 1
229960005486 vaccine Drugs 0.000 abstract 4
150000001875 compounds Chemical class 0.000 abstract 2
RBXSZQRSEGYDFG-GUBZILKMSA-N Glu-Lys-Ser Chemical compound [H]N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(O)=O RBXSZQRSEGYDFG-GUBZILKMSA-N 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
108010064539 amyloid beta-protein (1-42) Proteins 0.000 abstract 1
239000000427 antigen Substances 0.000 abstract 1
102000036639 antigens Human genes 0.000 abstract 1
108091007433 antigens Proteins 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000010534 mechanism of action Effects 0.000 abstract 1
230000000324 neuroprotective effect Effects 0.000 abstract 1
230000001777 nootropic effect Effects 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Gastroenterology & Hepatology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Immunology (AREA)
Epidemiology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Toxicology (AREA)
Marine Sciences & Fisheries (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Plant Substances (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Steroid Compounds (AREA)
Medicinal Preparation (AREA)

DK05107898T 2003-01-14 2004-01-13 Fremgangsmåde til forebyggelse og behandling af Alzheimers sygdom (AD) DK1679319T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
AT362003		2003-01-14
AT0146403A AT413945B (de)	2003-01-14	2003-09-17	Impfstoff für die alzheimer-krankheit
PCT/EP2004/000162 WO2004062556A2 (en)	2003-01-14	2004-01-13	Methods for preventing and treating alzheimer’s disease (ad)

Publications (1)

Publication Number	Publication Date
DK1679319T3 true DK1679319T3 (da)	2008-01-28

Family

ID=32714004

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK05107898T DK1679319T3 (da)	2003-01-14	2004-01-13	Fremgangsmåde til forebyggelse og behandling af Alzheimers sygdom (AD)
DK04701585.4T DK1583774T3 (da)	2003-01-14	2004-01-13	Fremgangsmåder til forebyggelse og behandling af alzheimers sygdom

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK04701585.4T DK1583774T3 (da)	2003-01-14	2004-01-13	Fremgangsmåder til forebyggelse og behandling af alzheimers sygdom

Country Status (14)

Country	Link
US (2)	US7732568B2 (de)
EP (2)	EP1679319B1 (de)
JP (2)	JP4547373B2 (de)
CN (2)	CN102526699A (de)
AT (3)	AT413945B (de)
CA (1)	CA2513218C (de)
CY (2)	CY1107146T1 (de)
DE (2)	DE602004009705T2 (de)
DK (2)	DK1679319T3 (de)
ES (2)	ES2339447T3 (de)
PL (1)	PL209989B1 (de)
PT (2)	PT1679319E (de)
SI (1)	SI1583774T1 (de)
WO (1)	WO2004062556A2 (de)

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AU2003303198A1 (en)	2002-12-19	2004-07-14	New York University	Method for treating amyloid disease
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AT413336B (de) *	2003-09-12	2006-02-15	Mattner Frank Dr	Apherese-vorrichtung
EP1711208A2 (de) *	2004-01-28	2006-10-18	Curix APS	Konjugate von amyloid-proteinen als impfstoffe gegen amyloid-bedingte erkrankungen
AT500483B1 (de)	2004-07-13	2006-01-15	Mattner Frank Dr	Set zur vorbeugung oder behandlung der alzheimer'schen erkrankung
AT413946B (de) *	2004-07-13	2006-07-15	Mattner Frank Dr	Impfstoff gegen die alzheimer-krankheit
HRP20140240T4 (hr)	2005-11-30	2017-02-24	Abbvie Inc.	Monoklonalna antitijela protiv amiloidnih beta proteina i njihova upotreba
US8691224B2 (en)	2005-11-30	2014-04-08	Abbvie Inc.	Anti-Aβ globulomer 5F7 antibodies
EP1959996A2 (de) *	2005-12-12	2008-08-27	AC Immune S.A.	Monoklonaler antikörper
EP1878747A1 (de)	2006-07-11	2008-01-16	greenovation Biotech GmbH	Glyco-hergestellte Antikörper
EP2046833B9 (de) *	2006-07-14	2014-02-19	AC Immune S.A.	Humanisierter antikörper gegen amyloid beta
US8455626B2 (en)	2006-11-30	2013-06-04	Abbott Laboratories	Aβ conformer selective anti-aβ globulomer monoclonal antibodies
US8895004B2 (en)	2007-02-27	2014-11-25	AbbVie Deutschland GmbH & Co. KG	Method for the treatment of amyloidoses
ES2529174T3 (es) *	2007-06-12	2015-02-17	Ac Immune S.A.	Anticuerpos humanizados para amiloide beta
US8613923B2 (en)	2007-06-12	2013-12-24	Ac Immune S.A.	Monoclonal antibody
US8048420B2 (en) *	2007-06-12	2011-11-01	Ac Immune S.A.	Monoclonal antibody
US20100297013A1 (en) *	2007-10-05	2010-11-25	Andrea Pfeifer	Humanized antibody
AU2008311367B2 (en) *	2007-10-05	2014-11-13	Ac Immune S.A.	Use of anti-amyloid beta antibody in ocular diseases
BRPI0818623A2 (pt) *	2007-10-05	2017-05-23	Ac Immune Sa	composição farmacêutica, e, métodos para reduzir a carga da placa na camada de célula de gânglio retinal de um animal, para reduzir a quantidade de placas na camada de célula de gânglio retinal de um animal, para diminuir a quantidade total de amilóide-beta solúvel na camada de célula de gânglio retinal de um animal, para prevenir, tratar e/ou aliviar os efeitos de uma doença ocular associada com anormalidades patológicas/mudanças no tecido do sistema visual, para monitorar doença ocular residual mínima associada com anormalidades patológicas/mudanças nos tecidos do sistema visual, para predizer responsividade de um paciente, e para reter ou diminuir a pressão ocular nos olhos de um animal
US8586706B2 (en) *	2007-10-25	2013-11-19	Kagoshima University	Peptide vaccine using mimic molecules of amyloid β peptide
EP2224000B1 (de) *	2007-10-29	2020-05-13	TAO Health Life Pharma Co., Ltd.	Antikörper und dessen verwendung
WO2009128948A1 (en)	2008-04-17	2009-10-22	Peptimmune, Inc.	Design and synthesis of directed sequence polymer compositions and antibodies thereof for the treatment of protein conformational disorders
AT506819B1 (de)	2008-06-12	2011-06-15	Affiris Forschungs Und Entwicklungs Gmbh	Vakzin zur behandlung von alzheimer-krankheit
CN102123726A (zh) *	2008-06-12	2011-07-13	阿费里斯股份公司	用于治疗与帕金森氏病有关的症状的化合物
AT506820B1 (de) *	2008-06-12	2011-07-15	Affiris Forschungs Und Entwicklungs Gmbh	Vakzine gegen alzheimer-krankheit
US8987419B2 (en)	2010-04-15	2015-03-24	AbbVie Deutschland GmbH & Co. KG	Amyloid-beta binding proteins
EP2598882B1 (de)	2010-07-30	2017-07-26	AC Immune S.A.	Sichere und funktionelle humanisierte antikörper für die verwendung in der behandlung von einer amyloidose
EP3533803B1 (de)	2010-08-14	2021-10-27	AbbVie Inc.	Anti-amyloid-beta antikörper
US20120328605A1 (en) *	2010-10-27	2012-12-27	Daniel Larocque	Compositions and uses
GB201113570D0 (en) *	2011-08-05	2011-09-21	Glaxosmithkline Biolog Sa	Vaccine
PT2579042E (pt)	2011-10-04	2014-09-09	Affiris Ag	Método para detecção de anticorpos específicos para a numa amostra biológica.
EP2787347A1 (de)	2013-04-03	2014-10-08	Affiris AG	Verfahren zur Erkennung von Aß-spezifischen Antikörpern in einer biologischen Probe
US10381614B2 (en) *	2013-04-17	2019-08-13	Samsung Sdi Co., Ltd.	Battery module
WO2015165961A1 (en)	2014-04-29	2015-11-05	Affiris Ag	Treatment and prevention of alzheimer's disease (ad)
RU2734924C2 (ru)	2015-11-03	2020-10-26	Аффирис Аг	Способ вакцинации против аутоантигена у пациента-человека
CN105237628B (zh) *	2015-11-17	2018-08-07	南开大学	一种用于治疗阿尔兹海默症的多肽
CN107022019B (zh) *	2016-11-24	2020-10-30	桂林医学院	一种用于脑内降铁除自由基的多肽、制备方法与应用
CN111201030B (zh)	2017-07-25	2024-11-01	真和制药有限公司	通过阻断tim-3和其配体的相互作用治疗癌症
WO2020160156A2 (en)	2019-01-30	2020-08-06	Immutics, Inc.	Anti-gal3 antibodies and uses thereof
EP4157338A4 (de)	2020-05-26	2024-11-13	TrueBinding, Inc.	Verfahren zur behandlung von entzündungskrankheiten durch galectin-3-blockierung
EP4486389A1 (de)	2022-02-28	2025-01-08	Tridem Bioscience GmbH & Co KG	Konjugat mit mindestens einem beta-glucan

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US5650489A (en) *	1990-07-02	1997-07-22	The Arizona Board Of Regents	Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
GB9022190D0 (en) *	1990-10-12	1990-11-28	Perham Richard N	Immunogenic material
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US7964192B1 (en)	1997-12-02	2011-06-21	Janssen Alzheimer Immunotherapy	Prevention and treatment of amyloidgenic disease
US6088993A (en)	1999-02-05	2000-07-18	Irace; Francisco D.	Closure system
EP1156825A2 (de)	1999-02-25	2001-11-28	SMITHKLINE BEECHAM BIOLOGICALS s.a.	Immunogene enthaltend ein peptid und einen von h.influenzae protein d abstammenden träger
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AU784568B2 (en) *	1999-09-03	2006-05-04	Ramot At Tel-Aviv University Ltd	Agents and compositions and methods utilizing same useful in diagnosing and/or treating or preventing plaque forming diseases
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ES2276895T3 (es) *	2002-05-07	2007-07-01	Institut Pasteur	Cribado de peptidos qque inhiben la union de pp1c a las proteinas bcl-2, bcl-xi y bcl-w.

2003
- 2003-09-17 AT AT0146403A patent/AT413945B/de not_active IP Right Cessation
2004
- 2004-01-13 ES ES04701585T patent/ES2339447T3/es not_active Expired - Lifetime
- 2004-01-13 CN CN2011103110387A patent/CN102526699A/zh active Pending
- 2004-01-13 SI SI200431399T patent/SI1583774T1/sl unknown
- 2004-01-13 DK DK05107898T patent/DK1679319T3/da active
- 2004-01-13 DE DE602004009705T patent/DE602004009705T2/de not_active Expired - Lifetime
- 2004-01-13 CA CA2513218A patent/CA2513218C/en not_active Expired - Fee Related
- 2004-01-13 US US10/540,551 patent/US7732568B2/en not_active Expired - Fee Related
- 2004-01-13 CN CN200480002213.2A patent/CN1826354B/zh not_active Expired - Fee Related
- 2004-01-13 JP JP2006500553A patent/JP4547373B2/ja not_active Expired - Fee Related
- 2004-01-13 AT AT04701585T patent/ATE458753T1/de active
- 2004-01-13 PT PT05107898T patent/PT1679319E/pt unknown
- 2004-01-13 WO PCT/EP2004/000162 patent/WO2004062556A2/en not_active Ceased
- 2004-01-13 AT AT05107898T patent/ATE376559T1/de active
- 2004-01-13 EP EP05107898A patent/EP1679319B1/de not_active Expired - Lifetime
- 2004-01-13 DE DE602004025668T patent/DE602004025668D1/de not_active Expired - Lifetime
- 2004-01-13 ES ES05107898T patent/ES2296084T3/es not_active Expired - Lifetime
- 2004-01-13 PT PT04701585T patent/PT1583774E/pt unknown
- 2004-01-13 PL PL378333A patent/PL209989B1/pl unknown
- 2004-01-13 DK DK04701585.4T patent/DK1583774T3/da active
- 2004-01-13 EP EP04701585A patent/EP1583774B1/de not_active Expired - Lifetime
2008
- 2008-01-17 CY CY20081100069T patent/CY1107146T1/el unknown
2010
- 2010-03-08 JP JP2010051012A patent/JP5282058B2/ja not_active Expired - Fee Related
- 2010-04-01 US US12/752,451 patent/US20110015131A1/en not_active Abandoned
- 2010-05-07 CY CY20101100399T patent/CY1110634T1/el unknown

Also Published As

Publication number	Publication date
PL209989B1 (pl)	2011-11-30
CY1110634T1 (el)	2015-04-29
CN102526699A (zh)	2012-07-04
EP1583774B1 (de)	2010-02-24
DE602004009705T2 (de)	2008-06-05
AU2004204349A1 (en)	2004-07-29
US7732568B2 (en)	2010-06-08
JP2010174024A (ja)	2010-08-12
JP4547373B2 (ja)	2010-09-22
AT413945B (de)	2006-07-15
DE602004025668D1 (de)	2010-04-08
PL378333A1 (pl)	2006-03-20
JP5282058B2 (ja)	2013-09-04
ATA14642003A (de)	2005-11-15
WO2004062556A8 (en)	2004-10-21
CA2513218C (en)	2013-06-25
ATE458753T1 (de)	2010-03-15
DK1583774T3 (da)	2010-05-03
ATE376559T1 (de)	2007-11-15
PT1583774E (pt)	2010-04-07
US20110015131A1 (en)	2011-01-20
HK1091499A1 (en)	2007-01-19
SI1583774T1 (sl)	2010-06-30
CN1826354A (zh)	2006-08-30
WO2004062556A3 (en)	2004-09-16
ES2339447T3 (es)	2010-05-20
JP2006515876A (ja)	2006-06-08
CA2513218A1 (en)	2004-07-29
PT1679319E (pt)	2008-01-10
DE602004009705D1 (de)	2007-12-06
ES2339447T8 (es)	2011-05-26
ES2296084T3 (es)	2008-04-16
CY1107146T1 (el)	2012-05-23
EP1583774A2 (de)	2005-10-12
EP1679319B1 (de)	2007-10-24
CN1826354B (zh)	2014-01-08
US20060111301A1 (en)	2006-05-25
EP1679319A1 (de)	2006-07-12
WO2004062556A2 (en)	2004-07-29

Publication	Publication Date	Title
DK1679319T3 (da)	2008-01-28	Fremgangsmåde til forebyggelse og behandling af Alzheimers sygdom (AD)
TW200602071A (en)	2006-01-16	Methods for preventing and treating alzheimer's disease (ad)
AT500379B1 (de)	2009-07-15	Tau-proteine
NO20045021L (no)	2005-01-18	Immunologiske metoder og preparater for behandling av Alzheimers sykdom
ATE283289T1 (de)	2004-12-15	Monoklonale antikörper, antigene sowie diagnose und therapie von bösartigen krankheiten
DK1368060T3 (da)	2010-08-30	HMGB1-proteininhibitorer og/eller antagonister til behandlingen af vaskulære sygdomme
NO20022531L (no)	2002-07-12	Vaksine for forebyggelse og behandling av Alzheimer- og amyloidrelaterte sykdommer
BR0213565A (pt)	2004-10-26	Anticorpo de anti-tnf alfa modificado
WO2004006952A3 (en)	2004-03-18	Therapeutic tuberculosis vaccines
DK2075007T3 (da)	2013-07-29	Behandling af Alzheimers sygdom
WO2001068708A3 (en)	2002-05-02	Human and humanized fap-alpha-specific antibodies
MA28418B1 (fr)	2007-02-01	Anticorps liant un recepteur de l'interleucine 4
NO20076021L (no)	2008-01-28	Antistoffer rettet mot amyloid-betapeptid og metoder som anvender de samme
WO2006029982A3 (de)	2006-09-21	Behandlung von atherosklerose
WO2004113386A3 (en)	2005-10-06	Modified hirudin proteins and t-cell epitopes in hirudin
DK1054895T3 (da)	2007-04-02	Et hidtil ukendt peptid, diagnostisk reagens og kit til detektion af rickettsiose
WO2004053117A3 (en)	2004-09-23	Serine protease
ATE395356T1 (de)	2008-05-15	Oberflächenprotein aus neisserien
WO2007030771A3 (en)	2008-11-20	Targeted identification of immunogenic peptides
DK1569961T3 (da)	2010-04-12	Splice variant af det menneskelige hypofysevæksthormon
WO2003070770A3 (en)	2003-12-24	Engineered human kunitz-type protease inhibitor
ATE338063T1 (de)	2006-09-15	Diagnostische verwendungen des t-zell proteins tzon7, der davon abgeleiteten peptide und des antikörpers
WO2002070560A3 (en)	2002-12-19	Nuclear hormone receptor ligand binding domain
DE69932815D1 (de)	2006-09-28	Cyclophilin als Allergen identifiziert
WO2002008393A3 (en)	2002-06-20	Serine protease from yersinia enterocolitica