DK169609B1 - Anvendelse af 4-substituerede indoloner til fremstilling af medikamenter til behandling af Parkinsons sygdom - Google Patents

Anvendelse af 4-substituerede indoloner til fremstilling af medikamenter til behandling af Parkinsons sygdom Download PDF

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Publication number
DK169609B1
DK169609B1 DK275488A DK275488A DK169609B1 DK 169609 B1 DK169609 B1 DK 169609B1 DK 275488 A DK275488 A DK 275488A DK 275488 A DK275488 A DK 275488A DK 169609 B1 DK169609 B1 DK 169609B1
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DK
Denmark
Prior art keywords
compound
disease
treatment
parkinson
hydrogen
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DK275488A
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Danish (da)
English (en)
Other versions
DK275488A (da
DK275488D0 (da
Inventor
David Andrew Arlwydd Owen
Original Assignee
Smith Kline French Lab
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Publication of DK275488A publication Critical patent/DK275488A/da
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DK275488A 1987-05-21 1988-05-19 Anvendelse af 4-substituerede indoloner til fremstilling af medikamenter til behandling af Parkinsons sygdom DK169609B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8712073 1987-05-21
GB878712073A GB8712073D0 (en) 1987-05-21 1987-05-21 Medicament

Publications (3)

Publication Number Publication Date
DK275488D0 DK275488D0 (da) 1988-05-19
DK275488A DK275488A (da) 1988-11-22
DK169609B1 true DK169609B1 (da) 1994-12-27

Family

ID=10617727

Family Applications (1)

Application Number Title Priority Date Filing Date
DK275488A DK169609B1 (da) 1987-05-21 1988-05-19 Anvendelse af 4-substituerede indoloner til fremstilling af medikamenter til behandling af Parkinsons sygdom

Country Status (20)

Country Link
US (2) US4824860A (fr)
EP (1) EP0299602B1 (fr)
JP (1) JPH062672B2 (fr)
AT (1) ATE83659T1 (fr)
AU (1) AU599792B2 (fr)
CA (1) CA1305421C (fr)
DE (1) DE3876877T2 (fr)
DK (1) DK169609B1 (fr)
ES (1) ES2052717T3 (fr)
GB (1) GB8712073D0 (fr)
GR (1) GR3007251T3 (fr)
HU (1) HU201871B (fr)
IE (1) IE63511B1 (fr)
LU (1) LU90098I2 (fr)
MX (1) MX9203543A (fr)
NL (1) NL970006I2 (fr)
NZ (1) NZ224709A (fr)
PH (1) PH23867A (fr)
PT (1) PT87542B (fr)
ZA (1) ZA883602B (fr)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9008605D0 (en) * 1990-04-17 1990-06-13 Smith Kline French Lab Process
GB9015095D0 (en) * 1990-07-09 1990-08-29 Smith Kline French Lab Therapeutic method
WO1993023035A2 (fr) * 1992-05-18 1993-11-25 Smithkline Beecham Plc Emploi de derives d'indolone dans le traitement de troubles de la memoire, du dysfonctionnement sexuel et de la maladie de parkinson
GB9300309D0 (en) * 1993-01-08 1993-03-03 Smithkline Beecham Plc Process
GB9511366D0 (en) * 1995-06-06 1995-08-02 Smithkline Beecham Plc Novel formulations
GB9517062D0 (en) * 1995-08-18 1995-10-25 Scherer Ltd R P Pharmaceutical compositions
US5807570A (en) * 1995-09-29 1998-09-15 Cygnus, Inc. Transdermal administration of ropinirole and analogs thereof
GB9612752D0 (en) * 1996-06-19 1996-08-21 Smithkline Beecham Plc Novel treatment
AU4088897A (en) * 1996-08-27 1998-03-19 American Home Products Corporation 4-aminoethoxy indolone derivatives
WO1999052870A1 (fr) * 1998-04-13 1999-10-21 American Home Products Corporation 4-amino-(ethylamino)-oxindoles utilises comme agonistes des autorecepteurs de la dopamine
US6176242B1 (en) 1999-04-30 2001-01-23 Medtronic Inc Method of treating manic depression by brain infusion
US6218421B1 (en) * 1999-07-01 2001-04-17 Smithkline Beecham P.L.C. Method of promoting smoking cessation
AR030557A1 (es) 2000-04-14 2003-08-27 Jagotec Ag Una tableta en multicapa de liberacion controlada y metodo de tratamiento
US6277875B1 (en) * 2000-07-17 2001-08-21 Andrew J. Holman Use of dopamine D2/D3 receptor agonists to treat fibromyalgia
DE10041478A1 (de) * 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
US7858602B2 (en) * 2000-10-16 2010-12-28 Rodriguez Victorio C Therapeutic and prophylactic uses of cell specific carbonic anhydrase enzymes in treating aging disorders due to oxidative stress and as growth factors of stem cells
US6871098B2 (en) * 2000-10-30 2005-03-22 Medtronic, Inc. Method for treating obsessive-compulsive disorder with electrical stimulation of the brain internal capsule
WO2004024163A1 (fr) * 2002-09-13 2004-03-25 Motac Neuroscience Limited Traitement de troubles du mouvement associes aux noyaux gris centraux
ATE360415T1 (de) * 2002-09-17 2007-05-15 Motac Neuroscience Ltd Behandlung von dyskinesie
DE10334188B4 (de) * 2003-07-26 2007-07-05 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung von Depressionen
DE10334187A1 (de) * 2003-07-26 2005-03-03 Schwarz Pharma Ag Substituierte 2-Aminotetraline zur Behandlung von Depressionen
WO2005051488A1 (fr) * 2003-11-26 2005-06-09 Pfizer Products Inc. Association d'agonistes de la dopamine et d'inhibiteurs de recaptage de la monoamine
DE10361258A1 (de) * 2003-12-24 2005-07-28 Schwarz Pharma Ag Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson
US7378439B2 (en) * 2004-01-20 2008-05-27 Usv, Ltd. Process for the preparation of 4-(2-dipropylaminoethyl)-1,3-dihydro-2H-indol-2-one hydrochloride
US20050197385A1 (en) * 2004-02-20 2005-09-08 Schwarz Pharma Ag Use of rotigotine for treatment or prevention of dopaminergic neuron loss
DE102004014841B4 (de) * 2004-03-24 2006-07-06 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms
WO2007048034A2 (fr) * 2005-10-21 2007-04-26 Caritas St. Elizabeth Medical Center Of Boston, Inc. Utilisation d'androgenes dans le traitement de la maladie de parkinson
ES2402376T3 (es) * 2006-04-06 2013-05-03 Nupathe Inc. Implantes para el tratamiento de estados asociados con dopamina
WO2008001204A2 (fr) * 2006-06-29 2008-01-03 Antares Pharma Ipl Ag Compositions transdermiques de pramipexole présentant des propriétés de perméation améliorées
TW200815045A (en) * 2006-06-29 2008-04-01 Jazz Pharmaceuticals Inc Pharmaceutical compositions of ropinirole and methods of use thereof
US20090247537A1 (en) * 2008-03-25 2009-10-01 William Dale Overfield Methods for preventing or treating bruxism using dopaminergic agents
CN101574341B (zh) * 2008-05-05 2012-12-19 北京德众万全医药科技有限公司 一种罗匹尼罗的口服固体药物组合物
US20110195117A1 (en) * 2008-09-01 2011-08-11 Lupin Limited Controlled release compositions of ropinirole
EP2452677A1 (fr) 2008-09-29 2012-05-16 Wockhardt Limited Forme posologique à libération prolongée de ropinirole
WO2010044108A2 (fr) 2008-10-17 2010-04-22 Rubicon Research Private Limited Formulations à libération contrôlée de ropinirole
US20100233259A1 (en) * 2008-12-12 2010-09-16 Pascal Grenier Dosage form of ropinirole
MX2012012069A (es) 2010-04-30 2012-11-22 Teikoku Pharma Usa Inc Composiciones transdermicas de propinilaminoindan.
KR101853082B1 (ko) 2011-03-24 2018-04-27 테이코쿠 팔마 유에스에이, 인코포레이티드 활성제층 및 활성제 변환층을 포함하는 경피 조성물
JP5913614B2 (ja) 2011-11-09 2016-04-27 テイコク ファーマ ユーエスエー インコーポレーテッド 皮膚新生物の処置方法
JP6050896B2 (ja) 2012-11-02 2016-12-21 テイコク ファーマ ユーエスエー インコーポレーテッド プロピニルアミノインダン経皮組成物
US20150313891A1 (en) * 2014-05-02 2015-11-05 Abbvie Inc. Neuronal nicotinic agonists and methods of use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4588740A (en) * 1982-12-07 1986-05-13 Smithkline Beckman Corporation Pharmaceutical methods using 4-aminoalkyl-2(3H)-indolones
US4452808A (en) * 1982-12-07 1984-06-05 Smithkline Beckman Corporation 4-Aminoalkyl-2(3H)-indolones

Also Published As

Publication number Publication date
HU201871B (en) 1991-01-28
NL970006I2 (nl) 1997-10-01
NZ224709A (en) 1997-02-24
DE3876877T2 (de) 1993-04-29
PT87542B (pt) 1992-09-30
IE63511B1 (en) 1995-05-03
GR3007251T3 (fr) 1993-07-30
HK1000913A1 (en) 1998-05-08
DK275488A (da) 1988-11-22
EP0299602B1 (fr) 1992-12-23
ZA883602B (en) 1989-04-26
JPS63303966A (ja) 1988-12-12
PH23867A (en) 1989-11-23
ATE83659T1 (de) 1993-01-15
NL970006I1 (nl) 1997-04-01
EP0299602A2 (fr) 1989-01-18
HUT47217A (en) 1989-02-28
DK275488D0 (da) 1988-05-19
JPH062672B2 (ja) 1994-01-12
ES2052717T3 (es) 1994-07-16
LU90098I2 (fr) 1997-09-25
US4824860A (en) 1989-04-25
PT87542A (pt) 1989-05-31
IE881469L (en) 1988-11-21
DE3876877D1 (de) 1993-02-04
EP0299602A3 (en) 1990-06-06
CA1305421C (fr) 1992-07-21
AU599792B2 (en) 1990-07-26
MX9203543A (es) 1992-07-01
US4912126A (en) 1990-03-27
GB8712073D0 (en) 1987-06-24
AU1644588A (en) 1988-11-24

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
CTFF Application for supplementary protection certificate (spc) filed

Free format text: CA 1997 00011, 970131

CTFG Supplementary protection certificate (spc) issued

Free format text: CA 1997 00011, 970131, EXPIRES: 20110702

PUP Patent expired