DK1708705T3 - Anvendelse af piperidinderivater til fremme af angiogenese - Google Patents

Anvendelse af piperidinderivater til fremme af angiogenese

Info

Publication number
DK1708705T3
DK1708705T3 DK05704342T DK05704342T DK1708705T3 DK 1708705 T3 DK1708705 T3 DK 1708705T3 DK 05704342 T DK05704342 T DK 05704342T DK 05704342 T DK05704342 T DK 05704342T DK 1708705 T3 DK1708705 T3 DK 1708705T3
Authority
DK
Denmark
Prior art keywords
piperidine derivatives
promote angiogenesis
angiogenesis
promote
piperidine
Prior art date
Application number
DK05704342T
Other languages
English (en)
Inventor
Ayako Hashimoto
Takashi Imaizumi
Goro Miyakoda
Toyoki Mori
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of DK1708705T3 publication Critical patent/DK1708705T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4468Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK05704342T 2004-01-29 2005-01-26 Anvendelse af piperidinderivater til fremme af angiogenese DK1708705T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004020859 2004-01-29
PCT/JP2005/001444 WO2005072734A1 (en) 2004-01-29 2005-01-26 Pharmaceutical composition for promoting angiogenesis

Publications (1)

Publication Number Publication Date
DK1708705T3 true DK1708705T3 (da) 2009-05-11

Family

ID=34823768

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05704342T DK1708705T3 (da) 2004-01-29 2005-01-26 Anvendelse af piperidinderivater til fremme af angiogenese

Country Status (21)

Country Link
US (1) US8445516B2 (da)
EP (1) EP1708705B1 (da)
JP (1) JP2012006973A (da)
KR (1) KR100868470B1 (da)
CN (1) CN100473383C (da)
AR (1) AR047464A1 (da)
AT (1) ATE422888T1 (da)
AU (1) AU2005207746B2 (da)
BR (1) BRPI0506578A (da)
CA (1) CA2553918C (da)
CY (1) CY1108933T1 (da)
DE (1) DE602005012799D1 (da)
DK (1) DK1708705T3 (da)
ES (1) ES2321310T3 (da)
MY (1) MY142362A (da)
PL (1) PL1708705T3 (da)
PT (1) PT1708705E (da)
RU (1) RU2354375C2 (da)
SI (1) SI1708705T1 (da)
TW (1) TWI369986B (da)
WO (1) WO2005072734A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8592435B2 (en) 2007-04-27 2013-11-26 Daiichi Sankyo Company, Limited Nitrogen-containing six-membered aromatic ring derivatives and pharmaceutical products containing the same

Family Cites Families (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3063996A (en) * 1959-03-02 1962-11-13 Smith Kline French Lab Substituted piperidinylalkyl phenothiazines
US3370063A (en) * 1964-10-05 1968-02-20 Mcneilab Inc Substituted dimethoxy indoles and method of making the same
NL6703315A (da) 1966-03-22 1967-09-25
BE754587A (fr) 1969-08-08 1971-02-08 Upjohn Co Nouveaux p-(trihalomethylquinolylamino) benzamides et leur procede de preparation
CH535767A (de) 1970-04-25 1973-04-15 Sandoz Ag Verfahren zur Herstellung neuer N-Phenäthylpiperidinderivate
GB1416872A (en) 1972-03-10 1975-12-10 Wyeth John & Brother Ltd 4-aminoquinoline derivatives
US3875185A (en) * 1972-07-27 1975-04-01 Gaf Corp Process for the production of 2-hydroxyethylpyrrolidone
US3875165A (en) 1973-02-22 1975-04-01 Wyeth John & Brother Ltd (4-Quinolylamino)-(N-piperidyl)benzamides and N-{8 (quinolylamino)-benzoyl{9 piperidines
JPS5165770A (ja) 1974-12-04 1976-06-07 Otsuka Pharma Co Ltd Karubosuchirirujudotaino seizoho
JPS5168574A (ja) 1974-12-07 1976-06-14 Otsuka Pharma Co Ltd Karubosuchirirujudotaino seizoho
JPS51118771A (en) 1975-04-09 1976-10-18 Otsuka Pharmaceut Co Ltd Method for preparing carbostyryl derivatives
JPS597707B2 (ja) 1975-06-23 1984-02-20 オオツカセイヤク カブシキガイシヤ カルボスチリルユウドウタイノ セイゾウホウ
JPS52283A (en) 1975-06-23 1977-01-05 Otsuka Pharmaceut Co Ltd Process for preparation of carbostyril derivatives
JPS5283380A (en) 1975-12-26 1977-07-12 Otsuka Pharmaceut Co Ltd Synthesis of thiocarbostyril derivatives
JPS52118474A (en) 1976-03-31 1977-10-04 Otsuka Pharmaceut Co Ltd Alpha-substituted aminoalkanyol-3,4-dihydrocarbostyril derivatives and method of preparing the same
JPS5416478A (en) 1977-07-08 1979-02-07 Otsuka Pharmaceut Co Ltd 3,4-dihydrocarbostyril herivative
PH14993A (en) 1977-07-12 1982-03-22 Sandoz Ltd Indole derivative and composition containing the same
GB1573186A (en) 1977-09-14 1980-08-20 Wyeth John & Brother Ltd 4-aminoquinoline derivatives
JPS5585520A (en) 1978-12-22 1980-06-27 Otsuka Pharmaceut Co Ltd Remedy for peptic ulcer
JPS56164183A (en) 1980-05-21 1981-12-17 Kyowa Hakko Kogyo Co Ltd Novel piperidine derivative
JPS56125385A (en) 1980-03-10 1981-10-01 Kyowa Hakko Kogyo Co Ltd Novel piperidine derivative
JPS56164184A (en) 1980-05-21 1981-12-17 Kyowa Hakko Kogyo Co Ltd Novel piperidine derivative
JPS56166188A (en) 1980-05-27 1981-12-21 Kyowa Hakko Kogyo Co Ltd Novel piperidine derivative
JPS56161386A (en) 1980-05-16 1981-12-11 Kyowa Hakko Kogyo Co Ltd Novel piperidine derivative
JPS5924990B2 (ja) 1979-11-21 1984-06-13 協和醗酵工業株式会社 新規なピペリジン誘導体
JPS5740482A (en) 1980-08-22 1982-03-06 Kyowa Hakko Kogyo Co Ltd Novel piperidine derivative
PH17194A (en) * 1980-03-06 1984-06-19 Otsuka Pharma Co Ltd Novel carbostyril derivatives,and pharmaceutical composition containing the same
JPS57171974A (en) 1981-04-15 1982-10-22 Otsuka Pharmaceut Co Ltd Carbostyril derivative
FI77852C (fi) * 1981-02-17 1989-05-10 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av nya, saosom hjaertmediciner anvaendbara substituerade amid- och (maettad heterocykel)karbonylkarbostyrilderivat.
JPS57154129A (en) 1981-03-16 1982-09-22 Otsuka Pharmaceut Co Ltd Cardiotonic drug
JPS57192383A (en) 1981-05-19 1982-11-26 Kyowa Hakko Kogyo Co Ltd New piperidine derivative and its preparation
FR2524467A1 (fr) 1982-03-30 1983-10-07 Adir Polymethylene-imines disubstituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
ZA834177B (en) 1982-06-10 1984-06-27 Beecham Wuelfing Gmbh & Co Kg Amine derivatives
DE3373466D1 (de) 1982-06-10 1987-10-15 Beecham Wuelfing Gmbh & Co Kg Amine derivatives
US4556660A (en) 1982-07-12 1985-12-03 Janssen Pharmaceutica N.V. N-(Bicyclic heterocyclyl)-4-piperidinamines
IN156065B (da) 1982-07-12 1985-05-04 Janssen Pharmaceutica Nv
DE3484096D1 (de) 1983-11-30 1991-03-14 Janssen Pharmaceutica Nv Bizyklisches heterozyklyl aufveisende n-(bizyklisches heterozyklyl-4-piperidinamine.
ZA852235B (en) 1984-03-26 1986-11-26 Janssen Pharmaceutica Nv Anti-virally active pyridazinamines
US5001125A (en) 1984-03-26 1991-03-19 Janssen Pharmaceutica N.V. Anti-virally active pyridazinamines
JPS61161262A (ja) 1985-01-08 1986-07-21 Sankyo Co Ltd ピペリジン誘導体
PH22302A (en) 1985-02-11 1988-07-22 Fujisawa Pharmaceutical Co Piperidine compounds
JPH0680054B2 (ja) 1985-06-19 1994-10-12 吉富製薬株式会社 ピペリジン誘導体
DE3529994A1 (de) * 1985-08-22 1987-02-26 Hoechst Ag Indolinonderivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
EP0232612B1 (en) * 1985-12-23 1990-04-04 Dr. Lo. Zambeletti S.p.A. Azacyclic compounds, processes for their preparation, and their use as pharmaceuticals
DK167187A (da) * 1986-04-02 1987-10-03 Otsuka Pharma Co Ltd Carbostyrilderivater og salte deraf, fremgangsmaade til fremstilling af saadanne forbindelser og laegemiddel indeholdende disse
ES2053480T3 (es) 1986-07-31 1994-08-01 Otsuka Pharma Co Ltd Un procedimiento para preparar un derivado de carboestirilo.
YU213587A (en) 1986-11-28 1989-06-30 Orion Yhtymae Oy Process for obtaining new pharmacologic active cateholic derivatives
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
CA1317939C (en) 1987-07-01 1993-05-18 Janssen Pharmaceutica Naamloze Vennootschap ¬(bicyclic heterocyclyl)methyl and -hetero| substituted hexahydro-1h-azepines and pyrrolidines
JP2544939B2 (ja) 1987-09-01 1996-10-16 大塚製薬株式会社 ベンゾヘテロ環誘導体
ATE133942T1 (de) 1987-11-27 1996-02-15 Eisai Co Ltd Cyclische amine und pharmakologische verbindungen
GB8805064D0 (en) 1988-03-03 1988-03-30 Wyeth John & Brother Ltd Piperidine derivatives
FI892362A7 (fi) 1988-06-01 1989-12-02 Eisai Co Ltd Buteeni- tai propeenihappojohdannainen
JPH02138161A (ja) 1988-11-19 1990-05-28 Mitsubishi Kasei Corp 置換ケイ皮酸アミド誘導体
JP2777159B2 (ja) 1988-12-22 1998-07-16 エーザイ株式会社 環状アミン誘導体を含有する医薬
DE3907974A1 (de) 1989-03-11 1990-09-13 Merck Patent Gmbh Indolderivate
JP2747013B2 (ja) 1989-05-19 1998-05-06 エーザイ株式会社 ブテン酸又はプロペン酸誘導体
FR2662162B1 (fr) * 1990-05-18 1995-01-20 Adir Nouveaux derives de l'amino piperidine, de l'amino pyrrolidine et de l'amino perhydroazepine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
DE4032766A1 (de) * 1990-10-16 1992-04-30 Basf Ag Phenylpiperidinoylamine und diese enthaltende arzneimittel
MY110227A (en) * 1991-08-12 1998-03-31 Ciba Geigy Ag 1-acylpiperindine compounds.
US5356904A (en) * 1992-10-07 1994-10-18 Merck & Co., Inc. Carbostyril oxytocin receptor antagonists
US5656642A (en) * 1993-04-07 1997-08-12 Otsuka Pharmaceutical Co., Ltd. Peripheral vasodilating agent containing piperidine derivative as active ingredient
JP2825755B2 (ja) * 1993-04-07 1998-11-18 大塚製薬株式会社 ピペリジン誘導体を有効成分とする末梢血管拡張剤および新規ピペリジン誘導体
JP2694319B2 (ja) 1993-12-24 1997-12-24 大塚製薬株式会社 抗潰瘍剤
JP4119506B2 (ja) 1997-12-05 2008-07-16 大日本印刷株式会社 薄板のトリミング装置
RU2214256C2 (ru) * 2001-02-09 2003-10-20 Седов Валерий Михайлович Средство для стимуляции пролиферации клеток, состав для стимуляции пролиферации клеток и способ лечения ран, ожогов и язв различной этиологии
RU2200574C1 (ru) * 2001-10-10 2003-03-20 Санкт-Петербургский государственный научно-исследовательский институт скорой помощи им. И.И. Джанелидзе Способ профилактики и лечения сердечной недостаточности, развившейся вследствие инфаркта миокарда
JP4282366B2 (ja) 2003-05-02 2009-06-17 住友ゴム工業株式会社 弾性クローラ
US6925716B2 (en) 2003-12-04 2005-08-09 Eveready Battery Company, Inc. Shaving apparatus
JP4916115B2 (ja) * 2004-01-29 2012-04-11 大塚製薬株式会社 血管新生促進剤
JP4329585B2 (ja) 2004-03-19 2009-09-09 村田機械株式会社 画像読取装置
JP5168574B2 (ja) 2008-10-20 2013-03-21 株式会社ジェイテクト ボールジョイントの製造方法
JP5165770B2 (ja) 2011-01-12 2013-03-21 大同特殊工業株式会社 耐熱可撓管

Also Published As

Publication number Publication date
BRPI0506578A (pt) 2007-04-10
RU2354375C2 (ru) 2009-05-10
EP1708705B1 (en) 2009-02-18
RU2006127474A (ru) 2008-02-10
ATE422888T1 (de) 2009-03-15
US8445516B2 (en) 2013-05-21
CA2553918A1 (en) 2005-08-11
SI1708705T1 (sl) 2009-06-30
CN100473383C (zh) 2009-04-01
PT1708705E (pt) 2009-04-14
WO2005072734A1 (en) 2005-08-11
AU2005207746A1 (en) 2005-08-11
US20090187025A1 (en) 2009-07-23
MY142362A (en) 2010-11-30
HK1095755A1 (zh) 2007-05-18
AR047464A1 (es) 2006-01-18
EP1708705A1 (en) 2006-10-11
DE602005012799D1 (de) 2009-04-02
ES2321310T3 (es) 2009-06-04
KR100868470B1 (ko) 2008-11-12
CA2553918C (en) 2011-06-21
PL1708705T3 (pl) 2009-07-31
AU2005207746B2 (en) 2007-08-16
TW200526211A (en) 2005-08-16
JP2012006973A (ja) 2012-01-12
CY1108933T1 (el) 2014-07-02
KR20060127053A (ko) 2006-12-11
CN1905877A (zh) 2007-01-31
TWI369986B (en) 2012-08-11

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