DK171027B1 - 5'-Adenosinderivater, pharmaceutiske præparater deraf og anvendelse deraf til fremstilling af pharmaceutiske præparater - Google Patents

5'-Adenosinderivater, pharmaceutiske præparater deraf og anvendelse deraf til fremstilling af pharmaceutiske præparater Download PDF

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Publication number
DK171027B1
DK171027B1 DK360189A DK360189A DK171027B1 DK 171027 B1 DK171027 B1 DK 171027B1 DK 360189 A DK360189 A DK 360189A DK 360189 A DK360189 A DK 360189A DK 171027 B1 DK171027 B1 DK 171027B1
Authority
DK
Denmark
Prior art keywords
formula
compounds
deoxy
mmol
amino
Prior art date
Application number
DK360189A
Other languages
Danish (da)
English (en)
Other versions
DK360189D0 (da
DK360189A (da
Inventor
Patrick Casara
Charles Danzin
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP88401896A external-priority patent/EP0351475A1/fr
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of DK360189D0 publication Critical patent/DK360189D0/da
Publication of DK360189A publication Critical patent/DK360189A/da
Application granted granted Critical
Publication of DK171027B1 publication Critical patent/DK171027B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK360189A 1988-07-21 1989-07-20 5'-Adenosinderivater, pharmaceutiske præparater deraf og anvendelse deraf til fremstilling af pharmaceutiske præparater DK171027B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP88401896 1988-07-21
EP88401896A EP0351475A1 (fr) 1988-07-21 1988-07-21 Inhibiteurs de S-adénosylméthionine-décarboxylase
EP89401845 1989-06-28
EP89401845A EP0358536B1 (fr) 1988-07-21 1989-06-28 Inhibiteurs de la S'-adénosylméthionedécarboxylase

Publications (3)

Publication Number Publication Date
DK360189D0 DK360189D0 (da) 1989-07-20
DK360189A DK360189A (da) 1990-01-22
DK171027B1 true DK171027B1 (da) 1996-04-22

Family

ID=26117870

Family Applications (1)

Application Number Title Priority Date Filing Date
DK360189A DK171027B1 (da) 1988-07-21 1989-07-20 5'-Adenosinderivater, pharmaceutiske præparater deraf og anvendelse deraf til fremstilling af pharmaceutiske præparater

Country Status (12)

Country Link
EP (1) EP0358536B1 (fr)
JP (1) JP2789228B2 (fr)
KR (1) KR0150633B1 (fr)
CN (1) CN1026115C (fr)
CA (1) CA1335201C (fr)
DK (1) DK171027B1 (fr)
FI (1) FI94644C (fr)
IE (1) IE81169B1 (fr)
IL (1) IL90996A (fr)
NO (1) NO171982C (fr)
NZ (1) NZ229955A (fr)
PT (1) PT91235B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA916464B (en) * 1990-08-22 1992-05-27 Merrell Dow Pharma 5'-amine substituted adenosine analogs as immunosuppressants
US5308837A (en) * 1990-08-22 1994-05-03 Merrell Dow Pharmaceuticals Inc. 5'-amine substituted adenosine analogs as immunosuppressants
CA2217696A1 (fr) 1995-04-25 1996-10-31 Oridigm Corporation Regulation des voies metaboliques par la s-adenosyl-methionine et son utilisation dans le diagnostic et le traitement
US6020139A (en) * 1995-04-25 2000-02-01 Oridigm Corporation S-adenosyl methionine regulation of metabolic pathways and its use in diagnosis and therapy
KR100456970B1 (ko) * 2001-12-31 2004-11-10 주식회사 디피아이 우레탄 변성 폴리에스테르 수지 조성물, 이의 제조 방법및 이를 포함하는 도료 조성물
KR100496049B1 (ko) * 2001-12-31 2005-06-17 주식회사 디피아이 열경화성 우레탄 변성 폴리에스테르 수지 조성물
EP1408028A1 (fr) * 2002-10-09 2004-04-14 Institut National De La Sante Et De La Recherche Medicale (Inserm) Inhibition de la S-adenosyl methionine decarboxylase comme traitement des infections dues au Herpes simplex virus
US8637485B2 (en) * 2007-08-02 2014-01-28 Southern Research Institute 5′,-substituted adenosynes preparation thereof and use as inhibitors of S-adenosylmethionine decarboxylase

Also Published As

Publication number Publication date
EP0358536A2 (fr) 1990-03-14
NO892977D0 (no) 1989-07-20
AU610740B2 (en) 1991-05-23
EP0358536B1 (fr) 1996-05-08
KR0150633B1 (ko) 1998-08-17
NO171982C (no) 1993-05-26
PT91235A (pt) 1990-02-08
PT91235B (pt) 1995-03-01
AU3886689A (en) 1990-02-01
CN1026115C (zh) 1994-10-05
IL90996A (en) 1994-11-28
KR910002891A (ko) 1991-02-26
FI94644B (fi) 1995-06-30
JP2789228B2 (ja) 1998-08-20
NZ229955A (en) 1991-03-26
IL90996A0 (en) 1990-02-09
DK360189D0 (da) 1989-07-20
FI94644C (fi) 1995-10-10
DK360189A (da) 1990-01-22
JPH02191296A (ja) 1990-07-27
CN1039422A (zh) 1990-02-07
FI893507A7 (fi) 1990-01-22
NO892977L (no) 1990-01-22
FI893507A0 (fi) 1989-07-20
NO171982B (no) 1993-02-15
IE892364L (en) 1990-01-21
IE81169B1 (en) 2000-05-31
EP0358536A3 (fr) 1991-04-03
CA1335201C (fr) 1995-04-11

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Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed

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