DK173783D0 - Fremgangsmade til fremstilling af imidazo (1,2-alfa)pyridiner - Google Patents

Fremgangsmade til fremstilling af imidazo (1,2-alfa)pyridiner

Info

Publication number: DK173783D0
Authority: DK; Denmark
Prior art keywords: radical; alkyl; hydrogen atom; optionally carrying; halogen atom
Prior art date: 1982-04-21

Application number

DK1737/83A

Other languages

English (en)

Other versions

DK173783A (da

Inventor

Jean-Pierre Kaplan

Pascal George

Jean-Michel Bernardon

Original Assignee

Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-04-21

Filing date

1983-04-20

Publication date

1983-04-20

1983-04-20 Application filed by Synthelabo filed Critical Synthelabo

1983-04-20 Publication of DK173783D0 publication Critical patent/DK173783D0/da

1983-10-22 Publication of DK173783A publication Critical patent/DK173783A/da

Links

RQMWVVBHJMUJNZ-UHFFFAOYSA-N 4-chloropyridin-2-amine Chemical compound NC1=CC(Cl)=CC=N1 RQMWVVBHJMUJNZ-UHFFFAOYSA-N 0.000 title 1
-1 C1-4 alkyl radical Chemical class 0.000 abstract 7
125000005843 halogen group Chemical group 0.000 abstract 4
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical compound [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 2
CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 2
125000000623 heterocyclic group Chemical group 0.000 abstract 2
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
KKFDJZZADQONDE-UHFFFAOYSA-N (hydridonitrato)hydroxidocarbon(.) Chemical compound O[C]=N KKFDJZZADQONDE-UHFFFAOYSA-N 0.000 abstract 1
125000002941 2-furyl group Chemical group O1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
RMRFFCXPLWYOOY-UHFFFAOYSA-N allyl radical Chemical compound [CH2]C=C RMRFFCXPLWYOOY-UHFFFAOYSA-N 0.000 abstract 1
230000000496 anti-anoxic effect Effects 0.000 abstract 1
230000001773 anti-convulsant effect Effects 0.000 abstract 1
239000002249 anxiolytic agent Substances 0.000 abstract 1
230000000949 anxiolytic effect Effects 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
QUPDWYMUPZLYJZ-UHFFFAOYSA-N ethyl Chemical compound C[CH2] QUPDWYMUPZLYJZ-UHFFFAOYSA-N 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
230000000147 hypnotic effect Effects 0.000 abstract 1
150000005234 imidazo[1,2-a]pyridines Chemical class 0.000 abstract 1
230000001939 inductive effect Effects 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
GRVDJDISBSALJP-UHFFFAOYSA-N methyloxidanyl Chemical compound [O]C GRVDJDISBSALJP-UHFFFAOYSA-N 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
DITHIFQMPPCBCU-UHFFFAOYSA-N propa-1,2-diene Chemical compound [CH]=C=C DITHIFQMPPCBCU-UHFFFAOYSA-N 0.000 abstract 1
230000007958 sleep Effects 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Neurology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pyridine Compounds (AREA)

DK173783A 1982-04-21 1983-04-20 Fremgangsmaade til fremstilling af imidazo (1,2-alfa)pyridiner DK173783A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8206841A FR2525602A1 (fr)	1982-04-21	1982-04-21	Imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
FR8206841		1982-04-21

Publications (2)

Publication Number	Publication Date
DK173783D0 true DK173783D0 (da)	1983-04-20
DK173783A DK173783A (da)	1983-10-22

Family

ID=9273216

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK173783A DK173783A (da)	1982-04-21	1983-04-20	Fremgangsmaade til fremstilling af imidazo (1,2-alfa)pyridiner

Country Status (19)

Country	Link
US (1)	US4492695A (da)
EP (1)	EP0092459B1 (da)
JP (1)	JPS58189180A (da)
AT (1)	ATE23860T1 (da)
AU (1)	AU553112B2 (da)
CA (1)	CA1254207A (da)
DE (1)	DE3367918D1 (da)
DK (1)	DK173783A (da)
ES (1)	ES8402298A1 (da)
FI (1)	FI73998C (da)
FR (1)	FR2525602A1 (da)
GR (1)	GR78577B (da)
HU (1)	HU189648B (da)
IE (1)	IE54923B1 (da)
IL (1)	IL68443A0 (da)
NO (1)	NO156048C (da)
NZ (1)	NZ203955A (da)
PT (1)	PT76574B (da)
ZA (1)	ZA832787B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3406329A1 (de) *	1984-02-22	1985-08-22	Merck Patent Gmbh, 6100 Darmstadt	Pyridone
FR2606410B1 (fr) *	1986-11-07	1989-02-24	Synthelabo	Imidazopyridines, leur preparation et leur application en therapeutique
US5364849A (en) *	1989-04-22	1994-11-15	John Wyeth & Brother, Limited	1-[3 or 4-[1-[4-piperazinyl]]-2 arylpropionyl or butryl]-heterocyclic derivatives
AU695301B2 (en) *	1993-07-06	1998-08-13	Pfizer Inc.	Bicyclic tetrahydro pyrazolopyridines
WO1998025926A1 (en) *	1996-12-11	1998-06-18	Takeda Chemical Industries, Ltd.	Imidazopyridine derivatives and their production
AUPP278498A0 (en)	1998-04-03	1998-04-30	Australian Nuclear Science & Technology Organisation	Peripheral benzodiazepine receptor binding agents
WO2001009131A1 (en) *	1999-07-30	2001-02-08	Zenyaku Kogyo Kabushiki Kaisha	Azaindolizinone derivatives and cerebral function improvers containing the same as the active ingredient
IT1318624B1 (it)	2000-07-14	2003-08-27	Dinamite Dipharma S P A In For	Processo per la preparazione di 2-fenil-imidazo (1,2-a)piridin-3-acetammidi.
SE0003186D0 (sv) *	2000-09-07	2000-09-07	Astrazeneca Ab	New process
US6596731B2 (en)	2001-03-27	2003-07-22	Hoffmann-La Roche Inc.	Substituted imidazo[1,2-A] pyridine derivatives
WO2010074753A1 (en)	2008-12-23	2010-07-01	Map Pharmaceuticals, Inc.	Inhalation devices and related methods for administration of sedative hypnotic compounds
WO2010117787A2 (en) *	2009-03-30	2010-10-14	The Brigham And Women's Hospital, Inc.	Inhibiting eph b-3 kinase
CN110483499A (zh)	2009-11-05	2019-11-22	圣母大学	咪唑并[1,2-a]吡啶类化合物及其合成及使用方法
CN103360387B (zh) *	2012-03-28	2016-12-14	江苏豪森药业集团有限公司	一种制备化合物唑吡坦的方法
US10919888B2 (en)	2015-09-17	2021-02-16	University Of Notre Dame Du Lac	Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection
WO2017214442A1 (en)	2016-06-08	2017-12-14	President And Fellows Of Harvard College	Methods and compositions for reducing tactile dysfunction and anxiety associated with autism spectrum disorder, rett syndrome, and fragile x syndrome
CN107163039A (zh) *	2017-05-11	2017-09-15	浙江工业大学	一种6‑甲基‑2‑对甲苯基咪唑并[1,2‑a]吡啶‑3‑甲醛的制备方法
CA3099751A1 (en)	2018-05-22	2019-11-28	President And Fellows Of Harvard College	Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment
AU2019279858A1 (en)	2018-05-29	2020-11-26	President And Fellows Of Harvard College	Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment
US12077512B2 (en)	2019-03-25	2024-09-03	President And Fellows Of Harvard College	Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1076089A (en) *	1965-11-09	1967-07-19	Selvi & C Lab Bioterapico	New derivatives of imidazo [1,2-a]-pyridine and a process for the manufacture thereof
FR2492382A1 (fr) *	1980-10-22	1982-04-23	Synthelabo	Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique

1982
- 1982-04-21 FR FR8206841A patent/FR2525602A1/fr active Granted
1983
- 1983-04-07 EP EP83400706A patent/EP0092459B1/fr not_active Expired
- 1983-04-07 AT AT83400706T patent/ATE23860T1/de not_active IP Right Cessation
- 1983-04-07 DE DE8383400706T patent/DE3367918D1/de not_active Expired
- 1983-04-13 US US06/484,611 patent/US4492695A/en not_active Expired - Fee Related
- 1983-04-20 CA CA000426243A patent/CA1254207A/en not_active Expired
- 1983-04-20 DK DK173783A patent/DK173783A/da active IP Right Grant
- 1983-04-20 HU HU831381A patent/HU189648B/hu not_active IP Right Cessation
- 1983-04-20 IE IE896/83A patent/IE54923B1/en not_active IP Right Cessation
- 1983-04-20 JP JP58070849A patent/JPS58189180A/ja active Granted
- 1983-04-20 FI FI831349A patent/FI73998C/fi not_active IP Right Cessation
- 1983-04-20 NZ NZ203955A patent/NZ203955A/en unknown
- 1983-04-20 GR GR71139A patent/GR78577B/el unknown
- 1983-04-20 IL IL68443A patent/IL68443A0/xx not_active IP Right Cessation
- 1983-04-20 NO NO831390A patent/NO156048C/no unknown
- 1983-04-20 PT PT76574A patent/PT76574B/pt not_active IP Right Cessation
- 1983-04-20 ZA ZA832787A patent/ZA832787B/xx unknown
- 1983-04-20 ES ES521651A patent/ES8402298A1/es not_active Expired
- 1983-04-20 AU AU13700/83A patent/AU553112B2/en not_active Ceased

Also Published As

Publication number	Publication date
AU1370083A (en)	1983-10-27
FR2525602B1 (da)	1984-06-22
FI73998B (fi)	1987-08-31
PT76574B (fr)	1986-02-27
GR78577B (da)	1984-09-27
NO156048C (no)	1987-07-15
FI73998C (fi)	1987-12-10
JPH0412270B2 (da)	1992-03-04
IE54923B1 (en)	1990-03-28
FI831349A0 (fi)	1983-04-20
HU189648B (en)	1986-07-28
DE3367918D1 (en)	1987-01-15
EP0092459B1 (fr)	1986-11-26
JPS58189180A (ja)	1983-11-04
AU553112B2 (en)	1986-07-03
DK173783A (da)	1983-10-22
NO831390L (no)	1983-10-24
NZ203955A (en)	1985-11-08
ZA832787B (en)	1983-12-28
IE830896L (en)	1983-10-21
PT76574A (fr)	1983-05-01
EP0092459A2 (fr)	1983-10-26
ES521651A0 (es)	1984-01-16
ES8402298A1 (es)	1984-01-16
ATE23860T1 (de)	1986-12-15
EP0092459A3 (en)	1984-02-01
IL68443A0 (en)	1983-07-31
CA1254207A (en)	1989-05-16
US4492695A (en)	1985-01-08
NO156048B (no)	1987-04-06
FR2525602A1 (fr)	1983-10-28
FI831349L (fi)	1983-10-22

Legal Events

Date	Code	Title	Description
1988-10-10	AHS	Application shelved for other reasons than non-payment
2001-10-08	B1	Patent granted (law 1993)

Publication	Publication Date	Title
FI73998B (fi)	1987-08-31	Saett att framstaella terapeutiskt anvaendbara imidazo/1,2- /pyridiner.
ES8207537A1 (es)	1982-09-16	Procedimiento de preparacion de imidazo (1,2-a)piridinas
ATE29255T1 (de)	1987-09-15	Succinimid-derivate und deren herstellung.
SE8003822L (sv)	1980-11-24	Nya 3-vinylcefalosporiner och forfarande for framstellning derav
ES546377A0 (es)	1987-04-01	Un procedimiento para la preparacion de oxindal-carboxamidas triciclicas.
ES8605515A1 (es)	1986-03-16	Un procedimiento para preparar 5-(alquilo inferior)-1,6-naftiridin-2(1h)-onas.
ES527739A0 (es)	1985-04-16	Un procedimiento para preparar derivados de pirimidina
DK150782A (da)	1982-10-04	Fremgangsmaade til fremstilling af imidazo(1,2a)quinolinderivater eller syreadditionssalte deraf
SE8300580D0 (sv)	1983-02-03	Substituerade 1,3,4-tiadiazolo (3,2-a)pyrimidiner och forfarande for deras framstellning
DE3161553D1 (en)	1984-01-05	Thiazolo(3,2-a)pyrimidine derivatives, their preparation and pharmaceutical compositions containing them
TW350843B (en)	1999-01-21	2-(4-pyrazolyloxy-pyrimidin-5-yl) acetic acid derivatives
DE3884319D1 (de)	1993-10-28	Imidazobenzodiazepine und ihre Säureadditionssalze, Verfahren und Zwischenprodukte zu ihrer Herstellung, ihre Verwendung als Arzneimittel und diese enthaltende Zubereitungen.
IT1150955B (it)	1986-12-17	Derivati 3h-naft(1.2-d)-imidazolici il procedimento per la loro preparazione, il loro uso come agenti antiinfiammatori e le composizioni farmaceutiche che li contengono
NO811185L (no)	1981-10-09	Fremgangsmaate for fremstilling av farmakologisk aktive tiazolderivater.
ATE8633T1 (de)	1984-08-15	Vinyl-3-cephalosporinverbindungen und ihre herstellung.
IL82419A (en)	1991-06-10	3-amino-dihydropyridines,their preparation and medicaments containing them
EP0093050A3 (en)	1984-02-01	Dithiino (1,4) (2,3-c) pyrrole derivatives, their preparation and pharmaceutical compositions containing them