DK1748077T3 - Fremgangsmåde til fremstilling af protein - Google Patents

Fremgangsmåde til fremstilling af protein

Info

Publication number
DK1748077T3
DK1748077T3 DK05734619.9T DK05734619T DK1748077T3 DK 1748077 T3 DK1748077 T3 DK 1748077T3 DK 05734619 T DK05734619 T DK 05734619T DK 1748077 T3 DK1748077 T3 DK 1748077T3
Authority
DK
Denmark
Prior art keywords
procedure
producing protein
protein
producing
Prior art date
Application number
DK05734619.9T
Other languages
English (en)
Inventor
Masayo Date
Yoshimi Kikuchi
Hiroshi Itaya
Nami Nakamura
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Application granted granted Critical
Publication of DK1748077T3 publication Critical patent/DK1748077T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
DK05734619.9T 2004-04-20 2005-04-20 Fremgangsmåde til fremstilling af protein DK1748077T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2004124196 2004-04-20
JP2005005896 2005-01-13
PCT/JP2005/007518 WO2005103278A1 (ja) 2004-04-20 2005-04-20 タンパク質の製造法

Publications (1)

Publication Number Publication Date
DK1748077T3 true DK1748077T3 (da) 2013-04-08

Family

ID=35196990

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05734619.9T DK1748077T3 (da) 2004-04-20 2005-04-20 Fremgangsmåde til fremstilling af protein

Country Status (5)

Country Link
US (1) US8597907B2 (da)
EP (1) EP1748077B1 (da)
JP (1) JP4730302B2 (da)
DK (1) DK1748077T3 (da)
WO (1) WO2005103278A1 (da)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0016995B1 (pt) 2000-01-21 2016-03-08 Ajinomoto Kk bactéria escherichia coli geneticamente modificada, e, método para produzir l-lisina
CA2518049C (en) * 2003-03-07 2013-05-07 Ajinomoto Co., Inc. Method of producing microbial transglutaminase
DK1748077T3 (da) 2004-04-20 2013-04-08 Ajinomoto Kk Fremgangsmåde til fremstilling af protein
JPWO2008099898A1 (ja) * 2007-02-15 2010-05-27 味の素株式会社 ジスルフィド結合導入トランスグルタミナーゼ
DE102008025926A1 (de) * 2008-05-29 2009-12-03 Henkel Ag & Co. Kgaa Sekretionsoptimierter Mikroorganismus
WO2010005099A1 (ja) * 2008-07-09 2010-01-14 味の素株式会社 アミノヒドロキシ安息香酸類の製造方法
WO2010101256A1 (ja) 2009-03-06 2010-09-10 味の素株式会社 放線菌由来の耐熱性トランスグルタミナーゼ
US8871477B2 (en) 2010-02-23 2014-10-28 Toray Industries, Inc. Process for production of cadaverine
CN107365388B (zh) 2011-06-23 2021-05-14 味之素株式会社 多聚体蛋白的制备方法
CN103917656B (zh) 2011-10-25 2016-09-28 味之素株式会社 蛋白质的分泌产生方法
WO2013065772A1 (ja) 2011-11-02 2013-05-10 味の素株式会社 タンパク質の分泌生産法
WO2013065869A1 (en) 2011-11-02 2013-05-10 Ajinomoto Co.,Inc. Method for secretory production of protein
JPWO2013118544A1 (ja) * 2012-02-08 2015-05-11 味の素株式会社 タンパク質の分泌生産法
US20140023618A1 (en) * 2012-07-23 2014-01-23 Applied Biology Systems and methods for treatment of androgenetic skin conditions by microbial organisms
JP5673986B1 (ja) * 2013-02-18 2015-02-18 味の素株式会社 タンパク質の沈殿による製造方法
RU2013119826A (ru) 2013-04-29 2014-11-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Коринеформная бактерия и способ получения гетерологичных гибридных белков
RU2646098C2 (ru) 2013-04-30 2018-03-01 Интас Фармасьютикалс Лтд Новый способ клонирования, экспрессии и очистки для получения ранибизумаба
ES2758096T3 (es) * 2015-03-25 2020-05-04 Senseup Gmbh Sensores para la detección y cuantificación de secreción microbiológica de proteínas
DK3287523T3 (da) 2015-04-24 2022-07-25 Ajinomoto Kk Fremgangsmåde til sekretorisk fremstilling af protein
EP3375883B1 (en) 2015-11-12 2021-02-03 Ajinomoto Co., Inc. Method for producing n epsilon -acyl-l-lysine
WO2017191817A1 (ja) 2016-05-02 2017-11-09 味の素株式会社 アジド基含有Ｆｃタンパク質
KR102335301B1 (ko) * 2016-10-21 2021-12-06 아지노모토 가부시키가이샤 단백질의 분비 생산법
EP3530747A4 (en) 2016-10-21 2020-07-22 Ajinomoto Co., Inc. SECRETORY PROTEIN PRODUCTION PROCESS
WO2018135027A1 (ja) 2017-01-19 2018-07-26 味の素株式会社 ヘキスロン酸残基が異性化されたヘパロサン化合物の製造方法
JP7613833B2 (ja) 2017-03-28 2025-01-15 味の素株式会社 Ｒｎａの製造方法
EP3415622A1 (en) 2017-06-14 2018-12-19 Evonik Degussa GmbH Method for production of fine chemicals using a corynebacterium secreting modified alpha-1,6-glucosidases
CN117417912A (zh) 2017-09-05 2024-01-19 味之素株式会社 2-o-硫酸化酶突变体和3-o-硫酸化酶突变体及其使用方法
AU2018334768B2 (en) 2017-09-25 2024-08-08 Ajinomoto Co., Inc. Protein production method and disaccharide production method
EP3696274A4 (en) 2017-10-10 2021-07-28 Ajinomoto Co., Inc. PROTEIN MANUFACTURING PROCESS
WO2019078095A1 (en) 2017-10-16 2019-04-25 Ajinomoto Co., Inc. PROCESS FOR PRODUCTION OF PROTEIN HAVING ALPHA-HYDROXYLANTIC PEPTIDYLGLYCIN MONOOXYGENASE ACTIVITY
BR112020016770A2 (pt) 2018-02-20 2020-12-15 Ajinomoto Co., Inc. Método para induzir silenciamento de rna e para produzir uma composição para induzir silenciamento de rna em um organismo-alvo, e, composição para induzir silenciamento de rna em um organismo-alvo
WO2019203368A1 (ja) 2018-04-20 2019-10-24 味の素株式会社 タンパク質の分泌生産法
EP3861109A1 (en) 2018-10-05 2021-08-11 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
AU2019364829B2 (en) 2018-10-25 2025-11-20 Ajinomoto Co., Inc. Method for secretory production of protein
KR20230023751A (ko) 2020-06-11 2023-02-17 아지노모토 가부시키가이샤 단백질의 제조법
KR20240032941A (ko) 2021-07-07 2024-03-12 아지노모토 가부시키가이샤 비천연 아미노산 함유 단백질의 분비 생산법
EP4417684A4 (en) 2021-10-11 2026-03-25 Ajinomoto Kk BACTERIA MODIFIED TO EXPRESS A PROTEIN TAT HETEROLOGUE
WO2023200008A1 (ja) 2022-04-15 2023-10-19 味の素株式会社 培養肉の製造方法
KR20250151452A (ko) 2023-02-16 2025-10-21 아지노모토 가부시키가이샤 단백질의 분비 생산법
CN121045365B (zh) * 2025-11-04 2026-02-27 肽源（广州）生物科技有限公司 一种重组纤连蛋白及其制备方法与应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965197A (en) * 1987-06-12 1990-10-23 Massachusetts Institute Of Technology Coryneform expression and secretion system
WO1993003158A1 (fr) * 1991-07-30 1993-02-18 Orsan Systeme d'expression et de secretion de proteines utilisables en particulier chez les corynebacteries
JPH06169780A (ja) 1992-12-07 1994-06-21 Mitsubishi Petrochem Co Ltd 膜蛋白質の膜への組み込みに関与する遺伝子ｄｎａ
JPH06277073A (ja) 1993-03-30 1994-10-04 Mitsubishi Petrochem Co Ltd 蛋白質のトランスロケーションマシナリーをコードする遺伝子ｄｎａ
JPH07107981A (ja) 1993-10-08 1995-04-25 Mitsubishi Chem Corp 新規ｄｎａ断片
JPH11169182A (ja) 1997-12-10 1999-06-29 Mitsubishi Chemical Corp コリネ型細菌内で蛋白質を効率よく培地中へ分泌させる変異型分泌装置遺伝子
US6022952A (en) * 1998-04-01 2000-02-08 University Of Alberta Compositions and methods for protein secretion
ATE532870T1 (de) * 1999-09-30 2011-11-15 Ajinomoto Kk Verfahren zur herstellung von transglutaminase
US7316924B2 (en) * 2000-09-18 2008-01-08 Genencor International, Inc. Twin-arginine translocation in Bacillus
DE60234247D1 (de) * 2001-03-30 2009-12-17 Ajinomoto Kk Verfahren zur sekretion und produktion von protein
JP2005520569A (ja) * 2002-03-23 2005-07-14 リサーチ　ディベロップメント　ファンデーション バクテリア内で複数のジスルフィド結合を有する蛋白質の分泌とその利用
AU2002950473A0 (en) * 2002-07-26 2002-09-12 Commonwealth Scientific And Industrial Research Organisation Expression system
CA2518049C (en) * 2003-03-07 2013-05-07 Ajinomoto Co., Inc. Method of producing microbial transglutaminase
DK1748077T3 (da) 2004-04-20 2013-04-08 Ajinomoto Kk Fremgangsmåde til fremstilling af protein

Also Published As

Publication number Publication date
US20070184525A1 (en) 2007-08-09
WO2005103278A1 (ja) 2005-11-03
JPWO2005103278A1 (ja) 2008-03-13
US8597907B2 (en) 2013-12-03
JP4730302B2 (ja) 2011-07-20
EP1748077B1 (en) 2013-02-27
EP1748077A4 (en) 2011-09-28
EP1748077A1 (en) 2007-01-31

Similar Documents

Publication Publication Date Title
DK1941026T3 (da) Fremgangsmåder til fremstilling af protein under anvendelse af anti-senescensforbindelser
DK1828164T3 (da) Fremgangsmåde til fremstilling af N-phenylpyrazol-1-carboxamider
DK1778668T3 (da) Fremgangsmåde til fremstilling af dihydropteridion
NO20071430L (no) Anti-OX4OL antistoffer
DK1852430T3 (da) Fremgangsmåde til fremstilling af proanthocyanidinoligomer
DK1575416T3 (da) Fremgangsmåder til diagnosticering af præeklampsi
DK2929891T3 (da) Fremgangsmåde til modulering af appetitten
DK1893586T3 (da) Fremgangsmåde til fremstilling af 1-alkyl-3-phenyluraciler
DE602005020968D1 (de) n dafür
DE602005012636D1 (de) Erung
DK1926582T3 (da) Fremgangsmåder til beredning af læder
EP1732707A4 (en) ACTIVATION METHOD
DK1809660T3 (da) Thymus-specifikt protein
DK1835816T3 (da) Fremgangsmåde til produktion af proteinhydrolysater
DK1831223T3 (da) Fremgangsmåde til fremstilling af L-biopterin
DK1834528T3 (da) Fremgangsmåde til fremstilling af gelé-agtige drikke
DK1699921T3 (da) Fremgangsmåde til fremstilling af tværbundne proteinkrystaller
DK1794111T3 (da) Fremgangsmåde til fremstilling af cyclopentanon
SE0400530L (sv) Förfarande
DE602005019940D1 (de) Linseneinrichtung
DK1912961T3 (da) Fremgangsmåde til fremstilling af bepromolin
DK1717311T3 (da) Fremgangsmåde til fremstilling af lactoperoxidase
DE502005007997D1 (de) Aftfahrzeug
DK1727792T3 (da) Fremgangsmåde til fremstilling af semicarbazoner
DE602005019938D1 (de) Linseneinrichtung