DK1748759T3 - Fremgangsmåder til at forøge hydrofobe forbindelsers opløselighed i vand af ved micellære dispersioner - Google Patents
Fremgangsmåder til at forøge hydrofobe forbindelsers opløselighed i vand af ved micellære dispersionerInfo
- Publication number
- DK1748759T3 DK1748759T3 DK05745705.3T DK05745705T DK1748759T3 DK 1748759 T3 DK1748759 T3 DK 1748759T3 DK 05745705 T DK05745705 T DK 05745705T DK 1748759 T3 DK1748759 T3 DK 1748759T3
- Authority
- DK
- Denmark
- Prior art keywords
- micellary
- dispersions
- procedures
- water
- hydrophobic compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000006185 dispersion Substances 0.000 title 1
- 230000002209 hydrophobic effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/834,816 US7345093B2 (en) | 2004-04-27 | 2004-04-27 | Methods of enhancing solubility of compounds |
| US66662305P | 2005-03-31 | 2005-03-31 | |
| PCT/US2005/014611 WO2005105041A2 (en) | 2004-04-27 | 2005-04-27 | Methods of enhancing solubility in water of hydrophobic compounds by micellar dispersions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1748759T3 true DK1748759T3 (da) | 2013-04-22 |
Family
ID=34968885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05745705.3T DK1748759T3 (da) | 2004-04-27 | 2005-04-27 | Fremgangsmåder til at forøge hydrofobe forbindelsers opløselighed i vand af ved micellære dispersioner |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1748759B1 (da) |
| DK (1) | DK1748759T3 (da) |
| WO (1) | WO2005105041A2 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007142212A1 (ja) * | 2006-06-08 | 2007-12-13 | Dainippon Sumitomo Pharma Co., Ltd. | 製剤組成物 |
| TW200932240A (en) * | 2007-10-25 | 2009-08-01 | Astellas Pharma Inc | Pharmaceutical composition containing lipophilic substance which inhibits IL-2 production |
| CN104523591B (zh) * | 2014-12-19 | 2019-01-18 | 西安力邦肇新生物科技有限公司 | 无致敏性、无痛丙泊酚脂肪微乳冻干制剂配方和制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2326337A (en) * | 1997-06-20 | 1998-12-23 | Phares Pharma Holland | Homogeneous lipid compositions for drug delivery |
| GB9715759D0 (en) * | 1997-07-26 | 1997-10-01 | Danbiosyst Uk | New emulsion formulations |
| KR100336090B1 (ko) * | 1998-06-27 | 2002-05-27 | 윤승원 | 오일, 지방산 또는 이들의 혼합물을 함유한 난용성 약물의 고형분산제제 |
| US6136846A (en) * | 1999-10-25 | 2000-10-24 | Supergen, Inc. | Formulation for paclitaxel |
| ATE290876T1 (de) * | 2000-05-04 | 2005-04-15 | Panacea Biotec Ltd | Pharmazeutische zusammensetzung enthaltend cyclosprin als aktiven bestandteil |
| DE60109295T2 (de) * | 2000-07-24 | 2006-04-13 | Sugen, Inc., South San Francisco | Selbstemulgierendes system zur abgabe von sehr wasserunlöslichen und lipophilen arzneimitteln |
| US6623765B1 (en) * | 2000-08-01 | 2003-09-23 | University Of Florida, Research Foundation, Incorporated | Microemulsion and micelle systems for solubilizing drugs |
| WO2002080883A2 (en) * | 2001-03-27 | 2002-10-17 | Phares Pharmaceutical Research N.V. | Method and composition for solubilising a biologically active compound with low water solubility |
-
2005
- 2005-04-27 DK DK05745705.3T patent/DK1748759T3/da active
- 2005-04-27 EP EP05745705A patent/EP1748759B1/en not_active Expired - Lifetime
- 2005-04-27 WO PCT/US2005/014611 patent/WO2005105041A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1748759A2 (en) | 2007-02-07 |
| WO2005105041A2 (en) | 2005-11-10 |
| EP1748759B1 (en) | 2013-03-27 |
| WO2005105041A3 (en) | 2006-03-02 |
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