DK175206B1 - Ekspressionskontrolsekvenser - Google Patents

Ekspressionskontrolsekvenser Download PDF

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Publication number
DK175206B1
DK175206B1 DK198603206A DK320686A DK175206B1 DK 175206 B1 DK175206 B1 DK 175206B1 DK 198603206 A DK198603206 A DK 198603206A DK 320686 A DK320686 A DK 320686A DK 175206 B1 DK175206 B1 DK 175206B1
Authority
DK
Denmark
Prior art keywords
dna sequence
promoter
gram
expression control
expression
Prior art date
Application number
DK198603206A
Other languages
Danish (da)
English (en)
Other versions
DK320686D0 (da
DK320686A (da
Inventor
Hermann Bujard
Stuart Le Grice
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK320686D0 publication Critical patent/DK320686D0/da
Publication of DK320686A publication Critical patent/DK320686A/da
Application granted granted Critical
Publication of DK175206B1 publication Critical patent/DK175206B1/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/832Bacillus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/848Escherichia
    • Y10S435/849Escherichia coli

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  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK198603206A 1985-07-05 1986-07-04 Ekspressionskontrolsekvenser DK175206B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8517071 1985-07-05
GB858517071A GB8517071D0 (en) 1985-07-05 1985-07-05 Gram-positive expression control sequence

Publications (3)

Publication Number Publication Date
DK320686D0 DK320686D0 (da) 1986-07-04
DK320686A DK320686A (da) 1987-01-06
DK175206B1 true DK175206B1 (da) 2004-07-12

Family

ID=10581857

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198603206A DK175206B1 (da) 1985-07-05 1986-07-04 Ekspressionskontrolsekvenser

Country Status (12)

Country Link
US (1) US4868111A (de)
EP (1) EP0207459B1 (de)
JP (2) JP2632809B2 (de)
AT (1) ATE62020T1 (de)
AU (1) AU594349B2 (de)
CA (1) CA1316850C (de)
DE (1) DE3678343D1 (de)
DK (1) DK175206B1 (de)
GB (1) GB8517071D0 (de)
IE (1) IE59165B1 (de)
IL (1) IL79291A (de)
NZ (1) NZ216688A (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5266474A (en) * 1987-06-24 1993-11-30 Genentech, Inc. Balanced inducible transcription system
DK443288A (da) * 1987-08-17 1989-02-18 Hoffmann La Roche Ekspressionskontrolsekvenser
US5726042A (en) * 1988-04-07 1998-03-10 Abbott Laboratories Expression of heterologous proteins in Bacillus megaterium utilizing sporulation promoters of Bacillus subtilis
GB8811761D0 (en) * 1988-05-18 1988-06-22 Thomae Gmbh Dr K Biosynthetic process for preparation of chemical compounds
US7049102B1 (en) 1989-09-22 2006-05-23 Board Of Trustees Of Leland Stanford University Multi-gene expression profile
FR2679568B1 (fr) * 1991-07-22 1994-09-02 Pasteur Institut Nouveau type de replicon gram-positif - construction de vecteurs recombinants le contenant.
JPH07504815A (ja) 1992-02-27 1995-06-01 マイクロバイアル テクニクス リミティド 乳酸菌における異種遺伝子の発現およびその発現産物
US6022730A (en) * 1994-06-17 2000-02-08 Robinson; Douglas H. Methods for the isolation of bacteria containing eukaryotic genes
US5629205A (en) * 1995-05-19 1997-05-13 Allelix Biopharmaceuticals Inc. Promoters for gene expression
US6194168B1 (en) * 1997-09-30 2001-02-27 Human Genome Sciences, Inc. Expression control sequences
US6146848A (en) * 1998-07-23 2000-11-14 The Hong Kong University Of Science & Technology Bacterial expression system
US6720174B1 (en) 1999-01-28 2004-04-13 Novozymes A/S Phytases
JP2002542169A (ja) * 1999-04-09 2002-12-10 テクラブ, インコーポレイテッド Clostridiumdifficileに対する、組換え毒素A/毒素Bワクチン
ATE474932T1 (de) * 2000-10-25 2010-08-15 Fujifilm Corp Methode zur analyse doppelsträngiger dna
WO2003065973A2 (en) * 2001-10-26 2003-08-14 Id Biomedical Corporation Of Washington Multivalent streptococcal vaccine compositions and methods for use
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
CA2545610C (en) 2003-11-19 2014-03-25 Dow Global Technolgies Inc. Auxotrophic pseudomonas fluorescens bacteria for recombinant protein expression
AU2004317306B2 (en) 2003-11-21 2010-09-02 Pelican Technology Holdings, Inc. Improved expression systems with Sec-system secretion
ES2663594T3 (es) 2004-01-16 2018-04-16 Pfenex Inc Expresión de proteínas de mamífero en Pseudomonas fluorescens
US8603824B2 (en) 2004-07-26 2013-12-10 Pfenex, Inc. Process for improved protein expression by strain engineering
GB0602173D0 (en) * 2006-02-03 2006-03-15 Avecia Ltd Expression system
PT2086642E (pt) 2006-10-18 2014-09-30 Periness Ltd Dnase para o tratamento de subfertilidade masculina
JP5714230B2 (ja) 2007-01-31 2015-05-07 フェネックス インコーポレイテッド 発現上昇のための細菌リーダー配列
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
JP5444553B2 (ja) 2007-04-27 2014-03-19 フェネックス インコーポレイテッド 微生物宿主を迅速にスクリーニングして、異種タンパク質発現の収率および/または質が改善されている特定の株を同定する方法
WO2010132341A2 (en) 2009-05-11 2010-11-18 Pfenex, Inc. Production of recombinant proteins utilizing non-antibiotic selection methods and the incorporation of non-natural amino acids therein
WO2011109556A2 (en) 2010-03-04 2011-09-09 Pfenex Inc. Method for producing soluble recombinant interferon protein without denaturing
EP2553102B1 (de) 2010-03-30 2015-12-09 Pfenex Inc. Hochleistungs-expression rekombinanter toxinproteine
NZ603033A (en) 2010-04-01 2014-06-27 Pfenex Inc Methods for g-csf production in a pseudomonas host cell
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
US11408007B2 (en) 2014-09-26 2022-08-09 Yale University Compositions and methods for biocontainment of microorganisms
JP6817939B2 (ja) 2014-12-01 2021-01-20 フェネックス インク. ペプチド産生のための融合パートナー
AU2018354069A1 (en) 2017-10-27 2020-06-11 Pelican Technology Holdings, Inc. Bacterial leader sequences for periplasmic protein expression
JP7784804B2 (ja) 2017-10-27 2025-12-12 フェネックス インク. 組み換えerwiniaアスパラギナーゼの製造のための方法
WO2019083794A1 (en) 2017-10-27 2019-05-02 Pfenex Inc. PROCESS FOR PRODUCING EAR ASPARAGINASE. RECOMBINED COLI
US11149280B2 (en) 2019-10-29 2021-10-19 Yale University Engineering organisms resistant to viruses and horizontally transferred genetic elements
WO2022211829A1 (en) 2021-03-30 2022-10-06 Jazz Pharmaceuticals Ireland Ltd. Dosing of recombinant l-asparaginase
EP4493688A2 (de) 2022-03-17 2025-01-22 Yale University Zusammensetzungen und verfahren zur expression synthetischer genetischer elemente über verschiedene mikroorganismen hinweg
CN117384923A (zh) * 2023-09-13 2024-01-12 深圳先进技术研究院 表达盒、表达载体、重组微生物、非核糖体肽合成基因簇的异源表达方法及应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4495280A (en) * 1981-05-20 1985-01-22 The Board Of Trustees Of The Leland Stanford Jr. University Cloned high signal strength promoters
GR81701B (de) 1983-01-18 1984-12-12 Lilly Co Eli
EP0115936A1 (de) * 1983-01-24 1984-08-15 Kabushiki Kaisha Yakult Honsha Chimere Plasmide

Also Published As

Publication number Publication date
JP2887248B2 (ja) 1999-04-26
AU594349B2 (en) 1990-03-08
NZ216688A (en) 1990-06-26
DE3678343D1 (de) 1991-05-02
JP2632809B2 (ja) 1997-07-23
DK320686D0 (da) 1986-07-04
CA1316850C (en) 1993-04-27
EP0207459B1 (de) 1991-03-27
AU5938586A (en) 1987-01-08
IL79291A0 (en) 1986-09-30
IE59165B1 (en) 1994-01-12
IE861806L (en) 1987-01-05
JPS6214786A (ja) 1987-01-23
IL79291A (en) 1991-06-30
JPH10229878A (ja) 1998-09-02
DK320686A (da) 1987-01-06
GB8517071D0 (en) 1985-08-14
EP0207459A2 (de) 1987-01-07
ATE62020T1 (de) 1991-04-15
US4868111A (en) 1989-09-19
EP0207459A3 (en) 1988-07-06

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