DK175446B1 - Isoleret DNA, rekombinant vektor og vært, hvilke indeholder et gen som koder for duxurubin-resistens, samt fremgangsmåder til opnåelse heraf - Google Patents

Isoleret DNA, rekombinant vektor og vært, hvilke indeholder et gen som koder for duxurubin-resistens, samt fremgangsmåder til opnåelse heraf Download PDF

Info

Publication number: DK175446B1
Authority: DK; Denmark
Prior art keywords: doxorubicin; dna; resistance; peucetius; vector
Prior art date: 1988-05-27

Application number

DK199000218A

Other languages

Danish (da)

English (en)

Other versions

DK21890A (da

DK21890D0 (da

Inventor

Marinella Caruso

Anna Luisa Colombo

Luisa Garofano

Francesca Torti

Giuseppe Zanella

Original Assignee

Pharmacia & Upjohn Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-05-27

Filing date

1990-01-26

Publication date

2004-10-25

1990-01-26 Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa

1990-01-26 Publication of DK21890A publication Critical patent/DK21890A/da

1990-01-26 Publication of DK21890D0 publication Critical patent/DK21890D0/da

2004-10-25 Application granted granted Critical

2004-10-25 Publication of DK175446B1 publication Critical patent/DK175446B1/da

Links

239000013598 vector Substances 0.000 title claims abstract description 26
108090000623 proteins and genes Proteins 0.000 title claims abstract description 21
238000000034 method Methods 0.000 title claims description 10
AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 claims abstract description 104
229960004679 doxorubicin Drugs 0.000 claims abstract description 52
239000012634 fragment Substances 0.000 claims abstract description 25
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin

Landscapes

Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicinal Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Saccharide Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

DK199000218A 1988-05-27 1990-01-26 Isoleret DNA, rekombinant vektor og vært, hvilke indeholder et gen som koder for duxurubin-resistens, samt fremgangsmåder til opnåelse heraf DK175446B1 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB888812697A GB8812697D0 (en)	1988-05-27	1988-05-27	Isolation & characterisation of genes resistant to anthracycline antibiotics
GB8812697		1988-05-27
PCT/EP1989/000588 WO1989011532A1 (en)	1988-05-27	1989-05-26	Isolation and characterisation of genes resistant to anthracycline antibiotics
EP8900588		1989-05-26

Publications (3)

Publication Number	Publication Date
DK21890A DK21890A (da)	1990-01-26
DK21890D0 DK21890D0 (da)	1990-01-26
DK175446B1 true DK175446B1 (da)	2004-10-25

Family

ID=10637720

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK199000218A DK175446B1 (da)	1988-05-27	1990-01-26	Isoleret DNA, rekombinant vektor og vært, hvilke indeholder et gen som koder for duxurubin-resistens, samt fremgangsmåder til opnåelse heraf

Country Status (19)

Country	Link
EP (1)	EP0371112B1 (de)
JP (1)	JP3240052B2 (de)
KR (1)	KR970010761B1 (de)
AT (1)	ATE115627T1 (de)
AU (1)	AU610411B2 (de)
CA (1)	CA1335575C (de)
DE (1)	DE68920007T2 (de)
DK (1)	DK175446B1 (de)
FI (1)	FI97728C (de)
GB (1)	GB8812697D0 (de)
GR (1)	GR1002049B (de)
HU (2)	HU217210B (de)
IE (1)	IE66718B1 (de)
IL (1)	IL90386A (de)
NZ (1)	NZ229237A (de)
PT (1)	PT90667B (de)
RU (1)	RU2118367C1 (de)
WO (1)	WO1989011532A1 (de)
ZA (1)	ZA893979B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AUPN799596A0 (en) *	1996-02-09	1996-03-07	Northern Sydney Area Health Service	Chemotherapy resistance gene

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
YU33730B (en) *	1967-04-18	1978-02-28	Farmaceutici Italia	Process for preparing a novel antibiotic substance and salts thereof
JPS6158589A (ja) *	1984-08-30	1986-03-25	Meiji Seika Kaisha Ltd	ビアラホス生産遺伝子及び耐性遺伝子
US4935340A (en) *	1985-06-07	1990-06-19	Eli Lilly And Company	Method of isolating antibiotic biosynthetic genes

1988
- 1988-05-27 GB GB888812697A patent/GB8812697D0/en active Pending
1989
- 1989-05-08 CA CA000598991A patent/CA1335575C/en not_active Expired - Fee Related
- 1989-05-23 GR GR890100339A patent/GR1002049B/el not_active IP Right Cessation
- 1989-05-23 IL IL9038689A patent/IL90386A/en not_active IP Right Cessation
- 1989-05-23 NZ NZ229237A patent/NZ229237A/en unknown
- 1989-05-24 PT PT90667A patent/PT90667B/pt not_active IP Right Cessation
- 1989-05-25 ZA ZA893979A patent/ZA893979B/xx unknown
- 1989-05-26 HU HU264/89A patent/HU217210B/hu unknown
- 1989-05-26 RU SU4743220A patent/RU2118367C1/ru not_active IP Right Cessation
- 1989-05-26 WO PCT/EP1989/000588 patent/WO1989011532A1/en not_active Ceased
- 1989-05-26 KR KR1019900700134A patent/KR970010761B1/ko not_active Expired - Fee Related
- 1989-05-26 EP EP89906078A patent/EP0371112B1/de not_active Expired - Lifetime
- 1989-05-26 AU AU36927/89A patent/AU610411B2/en not_active Ceased
- 1989-05-26 AT AT89906078T patent/ATE115627T1/de not_active IP Right Cessation
- 1989-05-26 JP JP50550789A patent/JP3240052B2/ja not_active Expired - Fee Related
- 1989-05-26 HU HU893264A patent/HUT52818A/hu not_active IP Right Cessation
- 1989-05-26 DE DE68920007T patent/DE68920007T2/de not_active Expired - Fee Related
- 1989-06-12 IE IE173089A patent/IE66718B1/en not_active IP Right Cessation
1990
- 1990-01-24 FI FI900359A patent/FI97728C/fi not_active IP Right Cessation
- 1990-01-26 DK DK199000218A patent/DK175446B1/da not_active IP Right Cessation

Also Published As

Publication number	Publication date
GB8812697D0 (en)	1988-06-29
IE66718B1 (en)	1996-01-24
AU3692789A (en)	1989-12-12
JP3240052B2 (ja)	2001-12-17
NZ229237A (en)	1992-05-26
KR900702024A (ko)	1990-12-05
KR970010761B1 (ko)	1997-06-30
HUT52818A (en)	1990-08-28
HU893264D0 (en)	1990-07-28
RU2118367C1 (ru)	1998-08-27
ATE115627T1 (de)	1994-12-15
DK21890A (da)	1990-01-26
DK21890D0 (da)	1990-01-26
EP0371112B1 (de)	1994-12-14
DE68920007T2 (de)	1995-04-27
IL90386A0 (en)	1989-12-15
ZA893979B (en)	1990-02-28
WO1989011532A1 (en)	1989-11-30
IL90386A (en)	1995-12-31
FI900359A0 (fi)	1990-01-24
PT90667B (pt)	1994-10-31
IE891730L (en)	1989-11-27
GR890100339A (el)	1990-03-12
EP0371112A1 (de)	1990-06-06
GR1002049B (en)	1995-11-16
CA1335575C (en)	1995-05-16
JPH02504470A (ja)	1990-12-20
PT90667A (pt)	1989-11-30
AU610411B2 (en)	1991-05-16
HU217210B (hu)	1999-12-28
FI97728B (fi)	1996-10-31
FI97728C (fi)	1997-02-10
DE68920007D1 (de)	1995-01-26

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