DK176183A - Beta-lactam-antibiotika, fremgangsmaade til fremstilling deraf samt deres anvendelse som laegemiddel - Google Patents

Beta-lactam-antibiotika, fremgangsmaade til fremstilling deraf samt deres anvendelse som laegemiddel Download PDF

Info

Publication number: DK176183A
Authority: DK; Denmark
Prior art keywords: beta; medicine; procedures; preparing; lactam antibiotics
Prior art date: 1982-04-22

Application number

DK176183A

Other languages

English (en)

Other versions

DK176183D0 (da

Inventor

Karl Georg Metzger

Wilfried Schroeck

Dieter Haebich

Paul Naab

Hans-Joachim Zeiler

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-04-22

Filing date

1983-04-21

Publication date

1983-10-23

1983-04-21 Application filed by Bayer Ag filed Critical Bayer Ag

1983-04-21 Publication of DK176183D0 publication Critical patent/DK176183D0/da

1983-10-23 Publication of DK176183A publication Critical patent/DK176183A/da

Links

239000003782 beta lactam antibiotic agent Substances 0.000 title 1
238000000034 method Methods 0.000 title 1
239000002132 β-lactam antibiotic Substances 0.000 title 1
229940124586 β-lactam antibiotics Drugs 0.000 title 1
150000003839 salts Chemical class 0.000 description 2
208000035143 Bacterial infection Diseases 0.000 description 1
239000002253 acid Substances 0.000 description 1
150000007513 acids Chemical class 0.000 description 1
239000003242 anti bacterial agent Substances 0.000 description 1
229940088710 antibiotic agent Drugs 0.000 description 1
208000022362 bacterial infectious disease Diseases 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
150000002148 esters Chemical class 0.000 description 1
125000006239 protecting group Chemical group 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
- C07D233/36—One oxygen atom with hydrocarbon radicals, substituted by nitrogen atoms, attached to ring nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Description

-antibiotika eventuelt befries for de tilstedeværende beskyttelsesgrupper og omdannes til de farmaceutisk anvendelige salte eller estere deraf, eller de frie syrer, om ønsket, fremstilles ud fra de fremkomne salte.

De her omhandlede forbindelser er anvendelige til bekæmpelse af bakterielle infektioner.

DK176183A 1982-04-22 1983-04-21 Beta-lactam-antibiotika, fremgangsmaade til fremstilling deraf samt deres anvendelse som laegemiddel DK176183A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19823215085 DE3215085A1 (de)	1982-04-22	1982-04-22	Ss-lactam-antibiotika, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE3215085		1982-04-22

Publications (2)

Publication Number	Publication Date
DK176183D0 DK176183D0 (da)	1983-04-21
DK176183A true DK176183A (da)	1983-10-23

Family

ID=6161699

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK176183A DK176183A (da)	1982-04-22	1983-04-21	Beta-lactam-antibiotika, fremgangsmaade til fremstilling deraf samt deres anvendelse som laegemiddel

Country Status (6)

Country	Link
US (1)	US4515789A (da)
EP (1)	EP0092722B1 (da)
JP (1)	JPS58192881A (da)
DE (2)	DE3215085A1 (da)
DK (1)	DK176183A (da)
ES (1)	ES8402286A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0237735B1 (en) *	1986-03-17	1994-03-30	Fujisawa Pharmaceutical Co., Ltd.	3,7-Disubstituted-3-cephem compounds and process for production of the same
EP0268892A3 (en) *	1986-11-06	1990-10-10	Nissan Chemical Industries Ltd.	Substituted-amido derivatives, method for preparation of the same and phytopathogenic fungicides containing the same
GB8713061D0 (en) *	1987-06-04	1987-07-08	Beecham Group Plc	Compounds
DE19625524C2 (de) *	1996-06-26	2000-11-30	Gruenenthal Gmbh	Neue synthetische Catechol-Antibiotika-Konjugate und diese enthaltende Arzneimittel
DE19654920A1 (de)	1996-06-26	1998-01-08	Gruenenthal Gmbh	Neue synthetische Catecholderivate, Verfahren zu ihrer Herstellung und ihre Verwendung
US7354888B2 (en) *	2004-11-10	2008-04-08	Danisco A/S	Antibacterial composition and methods thereof comprising a ternary builder mixture

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2727586A1 (de) *	1977-06-20	1979-01-04	Bayer Ag	Methoxy-beta-lactam-antibiotica, verfahren zu ihrer herstellung sowie ihre verwendung
GB1584400A (en) *	1976-12-24	1981-02-11	Bayer Ag	(2-oxo-imidazoliden-1-yl(carbonylamino)-acetamido-cephalosporins and penicillins
DE2732283A1 (de) *	1977-07-16	1979-01-25	Bayer Ag	Beta-lactam-verbindungen
US4206116A (en) *	1978-10-16	1980-06-03	Bristol-Myers Company	Novel penicillins

1982
- 1982-04-22 DE DE19823215085 patent/DE3215085A1/de not_active Withdrawn
1983
- 1983-04-07 US US06/483,062 patent/US4515789A/en not_active Expired - Fee Related
- 1983-04-11 DE DE8383103473T patent/DE3365979D1/de not_active Expired
- 1983-04-11 EP EP83103473A patent/EP0092722B1/de not_active Expired
- 1983-04-20 JP JP58068482A patent/JPS58192881A/ja active Pending
- 1983-04-21 ES ES521714A patent/ES8402286A1/es not_active Expired
- 1983-04-21 DK DK176183A patent/DK176183A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP0092722A1 (de)	1983-11-02
DE3215085A1 (de)	1983-10-27
DE3365979D1 (en)	1986-10-16
DK176183D0 (da)	1983-04-21
EP0092722B1 (de)	1986-09-10
ES521714A0 (es)	1984-01-16
JPS58192881A (ja)	1983-11-10
US4515789A (en)	1985-05-07
ES8402286A1 (es)	1984-01-16

Similar Documents

Publication	Publication Date	Title
DK518683D0 (da)	1983-11-14	Fremgangsmade til fremstilling af 4"epi-9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin a eller farmaceutisk acceptable syreadditionssalte deraf og mellemprodukter ved fremgangsmaden
DK149308C (da)	1986-12-08	Analogifremgangs-maade til fremstilling af trans-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamin-derivater eller farmaceutisk acceptablesyreadditionssalte deraf
DK310383D0 (da)	1983-07-05	14-fluormorphinaner, fremgangsmade til fremstilling deraf samt deres anvendelse som laegemidler
DK151010C (da)	1988-06-13	Analogifremgangsmaade til fremstilling af n-(substitueret aminoalkyl)-2-oxo-1-pyrrolidinacetamider eller farmaceutisk acceptable syreadditionssalte deraf
DK398583A (da)	1984-03-03	Spergualin-beslaegtede forbindelser, fremgangsmaader til fremstilling deraf samt deres anvendelse som laegemidler
DK156252C (da)	1989-12-18	Analogifremgangsmaade til fremstilling af di-, tri- eller tetrapeptidderivater eller salte deraf
DK158658C (da)	1990-12-31	Analogifremgangsmaade til fremstilling af 9-aminoalkylfluorener eller farmaceutisk acceptable salte deraf
DK157890C (da)	1990-07-23	Fremgangsmaade til fremstilling af et antibiotikum, bmg162-af2, eller et pharmaceutisk acceptabelt salt deraf
IT1131904B (it)	1986-06-25	Sistema per l'infusione di medicamenti,controllato magenticamente
DK157451C (da)	1990-05-21	Analogifremgangsmaade til fremstilling af 2,4-diamino-6-alkoxybenzyl-5-methylpyridooe2,3-daapyrimidiner eller farmaceutisk acceptable syreadditionssalte deraf
DK151805C (da)	1988-06-13	Analogifremgangsmaade til fremstilling af 20,21-di-nor-eburnameninderivater eller farmaceutisk acceptable additionssalte deraf
DK165005C (da)	1993-02-08	Analogifremgangsmaade til fremstilling af 4,5-dihydro-4-oxofuran-2-carboxylsyrederivater eller terapeutisk acceptable salte deraf
DK143445C (da)	1981-12-21	Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive substituerede 1,1-diphenyl-3-amino-propanol-forbindelser
DK166210C (da)	1993-08-16	Krystallinske cephalosporin-hydrohalogenidsalte, fremgangsmaade til fremstilling deraf samt deres anvendelse som laegemidler
DK422488D0 (da)	1988-07-28	Arylpyrroler, fremgangsmaader til deres fremstilling samt deres anvendelse som insecticider, acaricider og nematodicider
DK382283D0 (da)	1983-08-19	Thiazol-derivater, fremgangsmade til fremstilling deraf samt deres anvendelse som laegemidler
DK138498B (da)	1978-09-18	Analogifremgangsmåde til fremstilling af antibiotikum A204I-derivater eller fysiologisk acceptable kationiske salte deraf.
DK176183D0 (da)	1983-04-21	Beta-lactam-antibiotika, fremgangsmade til fremstilling deraf samt deres anvendelse som laegemiddel
DK442183A (da)	1984-03-29	Thiatriazin-derivater, fremgangsmaader til fremstilling deraf og deres anvendelse som laegemidler
DK154431C (da)	1989-04-10	Analogifremgangsmaade til fremstilling af 10-halogen-e-homoeburnanderivater eller epimere, optisk aktive antipoder eller fysiologisk acceptable syreadditionssalte deraf
DK150481C (da)	1987-09-28	Analogifremgangsmaade til fremstilling af 3',4'-dihydro-spiro-(imidazolidin-4,1'-(2'h)-naphthalen)-5-on eller farmaceutisk acceptable syreadditionssalte deraf
DK72282A (da)	1982-08-21	Fremgangsmaade til fremstilling af bis-estere af 1,1-alkandioler med 2beta-acetoxymethyl-2alfa-methyl-(5r)penam-3alfa-carboxylsyre-1,1-dioxid og en 6-acylaminopenicillansyre eller farmaceutisk acceptable salte deraf
DK143197C (da)	1981-11-23	Analogifremgangsmaade til fremstilling af 5,7-dihydroxy-tetrahydroisoquinoliner eller farmaceutisk acceptable syreadditionssalte deraf
FR2401162A1 (fr)	1979-03-23	Antibiotique derive d'un streptomyces, utilisable comme medicament
DK144855C (da)	1982-11-08	Fremgangsmaade til fremstilling af det antibiotiske stof sisomicin eller terapeutisk acceptable salte deraf

Legal Events

Date	Code	Title	Description
1984-12-08	ATS	Application withdrawn