DK1778265T3 - Guanylhydrazoneforbindelser, sammensætninger, fremgangsmåder og anvendelse - Google Patents

Guanylhydrazoneforbindelser, sammensætninger, fremgangsmåder og anvendelse

Info

Publication number
DK1778265T3
DK1778265T3 DK05785277.4T DK05785277T DK1778265T3 DK 1778265 T3 DK1778265 T3 DK 1778265T3 DK 05785277 T DK05785277 T DK 05785277T DK 1778265 T3 DK1778265 T3 DK 1778265T3
Authority
DK
Denmark
Prior art keywords
compositions
methods
guanylhydrazone compounds
guanylhydrazone
compounds
Prior art date
Application number
DK05785277.4T
Other languages
English (en)
Inventor
Thais M Sielecki-Dzurdz
Original Assignee
Ferring Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring Bv filed Critical Ferring Bv
Application granted granted Critical
Publication of DK1778265T3 publication Critical patent/DK1778265T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/30—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
    • C07C233/33—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicinal Preparation (AREA)
DK05785277.4T 2004-08-17 2005-08-17 Guanylhydrazoneforbindelser, sammensætninger, fremgangsmåder og anvendelse DK1778265T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60199204P 2004-08-17 2004-08-17
PCT/US2005/029301 WO2006023586A2 (en) 2004-08-17 2005-08-17 Guanylhydrazone compounds, compositions, methods of making and using

Publications (1)

Publication Number Publication Date
DK1778265T3 true DK1778265T3 (da) 2013-06-24

Family

ID=35968147

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05785277.4T DK1778265T3 (da) 2004-08-17 2005-08-17 Guanylhydrazoneforbindelser, sammensætninger, fremgangsmåder og anvendelse

Country Status (13)

Country Link
US (3) US7291647B2 (da)
EP (2) EP1778265B1 (da)
JP (2) JP5198863B2 (da)
CN (2) CN101010094B (da)
AU (1) AU2005277456B2 (da)
BR (1) BRPI0514452A8 (da)
CA (1) CA2577156C (da)
DK (1) DK1778265T3 (da)
ES (1) ES2422425T3 (da)
MX (1) MX2007001928A (da)
PL (1) PL1778265T3 (da)
PT (1) PT1778265E (da)
WO (1) WO2006023586A2 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1778265T3 (pl) * 2004-08-17 2013-10-31 Ferring Bv Związki guanylohydrazonowe, kompozycje, sposoby wytwarzania i stosowania
WO2008002465A2 (en) * 2006-06-23 2008-01-03 The Feinstein Institute For Medical Research INHIBITORS OF Aβ AND SYNUCLEIN AGGREGATION
RU2477271C2 (ru) * 2011-01-12 2013-03-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Кабардино-Балкарский государственный университет им. Х.М. Бербекова" (КБГУ) Моно- и дикетимины на основе 4,4'-диацетилдифенилоксида и гуанидина и способ их получения
CN109580873A (zh) * 2018-12-27 2019-04-05 湖北航天化学技术研究所 一种三氨基硝酸胍纯度的测定方法
CN116102468B (zh) * 2023-02-22 2024-07-09 中国科学技术大学 靶向人脂质运载蛋白2的先导化合物或其药学上可接受的盐及其制备方法与应用
WO2025045826A1 (en) * 2023-08-25 2025-03-06 The Cultivated B. Gmbh Compounds for activation of fgfr1 signaling

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH474486A (de) * 1965-11-19 1969-06-30 Ciba Geigy Verfahren zur Herstellung neuer Diphenylharnstoffe
IT1055433B (it) * 1976-02-23 1981-12-21 Anic Spa Metodo per la purificazione di acqua di scarico contenenti composti organici di carattere anioni co e mezzi adatti allo scopo
US5272165A (en) * 1984-03-19 1993-12-21 The Rockefeller University 2-alkylidene-aminoguanidines and methods of use therefor
US7425543B2 (en) 1992-11-16 2008-09-16 The Corporation Of Mercer University Microencapsulated materials and method of making same
US6008255A (en) 1994-01-21 1999-12-28 The Picower Institute For Medical Research Guanylhydrazones and their use to treat inflammatory conditions
US5599984A (en) 1994-01-21 1997-02-04 The Picower Institute For Medical Research Guanylhydrazones and their use to treat inflammatory conditions
JP3823330B2 (ja) * 1994-11-09 2006-09-20 昭和電工株式会社 Ｎ−ホスホノメチルグリシンの単離方法
CA2271693C (en) 1996-11-15 2009-01-20 The Picower Institute For Medical Research Guanylhydrazones useful for treating diseases associated with t cell activation
US6319894B1 (en) 1997-01-08 2001-11-20 The Picower Institute For Medical Research Complexes and combinations of fetuin with therapeutic agents
ES2250363T3 (es) 2000-02-02 2006-04-16 Dorian Bevec Guanilhidrazonas aromaticas farmaceuticamente activas.
AU2001269092A1 (en) * 2000-06-27 2002-01-08 Axxima Pharmaceuticals Ag Inhibitors of hepatitis b virus infection
WO2003006426A1 (en) * 2001-07-13 2003-01-23 Axxima Pharmaceuticals Ag Aromatic guanylhydrazones as effective compounds against neurodiseases
US7001924B2 (en) 2001-09-21 2006-02-21 Message Pharmaceuticals Inhibitors of RNase P proteins as antibacterial compounds
WO2003072135A2 (en) 2002-02-26 2003-09-04 North Shore-Long Island Jewish Research Insitute Inhibition of inflammatory cytokine production by stimulation of brain muscarinic receptors
EP1389480A1 (en) * 2002-08-14 2004-02-18 Mondobiotech Interferon SA Therapeutical use of guanylhydrazones for the inhibition of CD83 dependent processes and dendritic cell maturation
US7244765B2 (en) * 2004-06-25 2007-07-17 Cytokine Pharmasciences, Inc Guanylhydrazone salts, compositions, processes of making and methods of using
PL1778265T3 (pl) * 2004-08-17 2013-10-31 Ferring Bv Związki guanylohydrazonowe, kompozycje, sposoby wytwarzania i stosowania

Also Published As

Publication number Publication date
US7291647B2 (en) 2007-11-06
US7863334B2 (en) 2011-01-04
PL1778265T3 (pl) 2013-10-31
EP1778265B1 (en) 2013-04-24
CN101010094B (zh) 2013-05-22
JP5198863B2 (ja) 2013-05-15
JP2013100291A (ja) 2013-05-23
US20110144189A1 (en) 2011-06-16
EP2543661B1 (en) 2016-12-07
CA2577156C (en) 2013-11-26
EP1778265A2 (en) 2007-05-02
WO2006023586A2 (en) 2006-03-02
JP5551755B2 (ja) 2014-07-16
PT1778265E (pt) 2013-08-05
BRPI0514452A (pt) 2008-06-10
US20080070959A1 (en) 2008-03-20
AU2005277456A1 (en) 2006-03-02
EP1778265A4 (en) 2010-01-06
ES2422425T3 (es) 2013-09-11
BRPI0514452A8 (pt) 2018-02-06
EP2543661A1 (en) 2013-01-09
CN101010094A (zh) 2007-08-01
CN102936212A (zh) 2013-02-20
MX2007001928A (es) 2007-04-17
WO2006023586A3 (en) 2007-01-04
US8247455B2 (en) 2012-08-21
US20060041002A1 (en) 2006-02-23
AU2005277456B2 (en) 2011-12-01
JP2008510703A (ja) 2008-04-10
CA2577156A1 (en) 2006-03-02

Similar Documents

Publication Publication Date Title
DK1765327T3 (da) Forbindelser, sammensætninger og fremgangsmåder
NO2019033I1 (no) regorafenib
HUS1800003I1 (hu) Fungicid kompozíciók
NO20053161D0 (no) Mikrobedrepende sammensetning.
EP1788047A4 (en) WATER REPELLENT / OIL-REPELLING COMPOSITION
DE602004021120D1 (de) Photopolymerisierbare zusammensetzung.
ITMI20041252A1 (it) Composizioni perfluoroelastomeriche
DE602005022897D1 (de) Piperidinylamino-thienoä2,3-dü-pyrimidinverbindungen
FR2862654B1 (fr) Composition amylacee filmogene
MA28948B1 (fr) Composition pesticide
IS7520A (is) Pyrimidínonefnasambönd, samsetningar og aðferðir
NO20055686L (no) Sammensetning, fremgangsmate til fremstilling derav, og anvendelse derav.
DE602005027222D1 (de) Schaumbare zusammensetzung
DE602005016978D1 (de) Quecksilberfreisetzende Zusammensetzungen
DK1611115T3 (da) Benzothiazolderivatforbindelser, sammensætninger og anvendelser deraf
DK1814977T3 (da) Arthrospira-baserede sammensætninger og anvendelser deraf
EP2111484A4 (en) POLYAMINE BRILLIANCE AGENT
DE602005017191D1 (de) Geruchsreduzierte waschstück-zusammensetzung
FI20041057L (fi) Pelkistysainekoostumus
DK1812120T3 (da) Hudbeskyttende, alkalinitetskontrollerende præparat og anvendelsen deraf
FR2871686B1 (fr) Composition anti-decoloration
BRPI0614413A2 (pt) composto, e, composição farmacêutica
PL1778265T3 (pl) Związki guanylohydrazonowe, kompozycje, sposoby wytwarzania i stosowania
DK1680134T3 (da) Sammensætninger og anvendelser deraf
NO20042486L (no) Novel contrast agent