DK1802277T3 - Liposomal sammensætning indeholdende en aktiv bestanddel til relaksation af glat muskulatur og terapeutisk anvendelse af sammensætningen - Google Patents

Liposomal sammensætning indeholdende en aktiv bestanddel til relaksation af glat muskulatur og terapeutisk anvendelse af sammensætningen

Info

Publication number: DK1802277T3
Authority: DK; Denmark
Prior art keywords: active ingredient; liposomes; composition; relaxation; smooth muscle
Prior art date: 2004-10-18

Application number

DK05802312.8T

Other languages

English (en)

Inventor

Andreas Wagner

Karola Vorauer-Uhl

Hermann Katinger

Original Assignee

Polymun Scient Immunbio Forsch

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-10-18

Filing date

2005-10-14

Publication date

2010-05-17

2005-10-14 Application filed by Polymun Scient Immunbio Forsch filed Critical Polymun Scient Immunbio Forsch

2010-05-17 Application granted granted Critical

2010-05-17 Publication of DK1802277T3 publication Critical patent/DK1802277T3/da

Links

239000004480 active ingredient Substances 0.000 title abstract 4
239000000203 mixture Substances 0.000 title abstract 3
230000004648 relaxation of smooth muscle Effects 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1
MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 abstract 5
239000002502 liposome Substances 0.000 abstract 3
BNRNXUUZRGQAQC-UHFFFAOYSA-N sildenafil Chemical compound CCCC1=NN(C)C(C(N2)=O)=C1N=C2C(C(=CC=1)OCC)=CC=1S(=O)(=O)N1CCN(C)CC1 BNRNXUUZRGQAQC-UHFFFAOYSA-N 0.000 abstract 2
ZOOGRGPOEVQQDX-UUOKFMHZSA-N 3',5'-cyclic GMP Chemical compound C([C@H]1O2)OP(O)(=O)O[C@H]1[C@@H](O)[C@@H]2N1C(N=C(NC2=O)N)=C2N=C1 ZOOGRGPOEVQQDX-UUOKFMHZSA-N 0.000 abstract 1
XKMLYUALXHKNFT-UUOKFMHZSA-N Guanosine-5'-triphosphate Chemical compound C1=2NC(N)=NC(=O)C=2N=CN1[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O XKMLYUALXHKNFT-UUOKFMHZSA-N 0.000 abstract 1
108010078321 Guanylate Cyclase Proteins 0.000 abstract 1
102000014469 Guanylate cyclase Human genes 0.000 abstract 1
-1 NO-synthetases Chemical compound 0.000 abstract 1
102000004861 Phosphoric Diester Hydrolases Human genes 0.000 abstract 1
108090001050 Phosphoric Diester Hydrolases Proteins 0.000 abstract 1
UDMBCSSLTHHNCD-KQYNXXCUSA-N adenosine 5'-monophosphate Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O UDMBCSSLTHHNCD-KQYNXXCUSA-N 0.000 abstract 1
102000030621 adenylate cyclase Human genes 0.000 abstract 1
108060000200 adenylate cyclase Proteins 0.000 abstract 1
239000012736 aqueous medium Substances 0.000 abstract 1
210000004392 genitalia Anatomy 0.000 abstract 1
RQFCJASXJCIDSX-UUOKFMHZSA-N guanosine 5'-monophosphate Chemical compound C1=2NC(N)=NC(=O)C=2N=CN1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O RQFCJASXJCIDSX-UUOKFMHZSA-N 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
150000002823 nitrates Chemical class 0.000 abstract 1
229940094443 oxytocics prostaglandins Drugs 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
150000003180 prostaglandins Chemical class 0.000 abstract 1
230000002040 relaxant effect Effects 0.000 abstract 1
230000035945 sensitivity Effects 0.000 abstract 1
208000012201 sexual and gender identity disease Diseases 0.000 abstract 1
208000015891 sexual disease Diseases 0.000 abstract 1
230000001568 sexual effect Effects 0.000 abstract 1
229960003310 sildenafil Drugs 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1
230000000699 topical effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
- A61K9/1278—Post-loading, e.g. by ion or pH gradient

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Reproductive Health (AREA)
Dispersion Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Gynecology & Obstetrics (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Pain & Pain Management (AREA)
Pregnancy & Childbirth (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Neurology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK05802312.8T 2004-10-18 2005-10-14 Liposomal sammensætning indeholdende en aktiv bestanddel til relaksation af glat muskulatur og terapeutisk anvendelse af sammensætningen DK1802277T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP04024753		2004-10-18
PCT/EP2005/011054 WO2006042701A1 (de)	2004-10-18	2005-10-14	Liposomale zusammensetzung einen wirkstoff zur relaxierung glatter muskulatur enthaltend, die herstellung dieser zusammensetzung und deren therapeutische verwendung

Publications (1)

Publication Number	Publication Date
DK1802277T3 true DK1802277T3 (da)	2010-05-17

Family

ID=35703778

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK05802312.8T DK1802277T3 (da)	2004-10-18	2005-10-14	Liposomal sammensætning indeholdende en aktiv bestanddel til relaksation af glat muskulatur og terapeutisk anvendelse af sammensætningen

Country Status (17)

Country	Link
US (1)	US8524274B2 (da)
EP (1)	EP1802277B1 (da)
JP (1)	JP5688199B2 (da)
KR (1)	KR101289917B1 (da)
CN (1)	CN101043874A (da)
AT (1)	ATE454884T1 (da)
AU (1)	AU2005296719B2 (da)
CA (1)	CA2583332C (da)
DE (1)	DE502005008880D1 (da)
DK (1)	DK1802277T3 (da)
EA (1)	EA011391B1 (da)
ES (1)	ES2339577T3 (da)
NZ (1)	NZ554183A (da)
PL (1)	PL1802277T3 (da)
PT (1)	PT1802277E (da)
SI (1)	SI1802277T1 (da)
WO (1)	WO2006042701A1 (da)

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US8871261B2 (en)	2012-09-19	2014-10-28	Transdermal Biotechnology, Inc.	Cancer treatments and compositions for use thereof
US8871257B2 (en)	2012-09-19	2014-10-28	Transdermal Biotechnology, Inc.	Prevention and treatment of cardiovascular diseases using systems and methods for transdermal nitric oxide delivery
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US9849160B2 (en)	2013-03-13	2017-12-26	Transdermal Biotechnology, Inc.	Methods and systems for treating or preventing cancer
US9393265B2 (en)	2013-03-13	2016-07-19	Transdermal Biotechnology, Inc.	Wound healing using topical systems and methods
US9314433B2 (en)	2013-03-13	2016-04-19	Transdermal Biotechnology, Inc.	Methods and systems for treating or preventing cancer
US9241899B2 (en)	2013-03-13	2016-01-26	Transdermal Biotechnology, Inc.	Topical systems and methods for treating sexual dysfunction
US9339457B2 (en)	2013-03-13	2016-05-17	Transdermal Biotechnology, Inc.	Cardiovascular disease treatment and prevention
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US9320758B2 (en)	2013-03-13	2016-04-26	Transdermal Biotechnology, Inc.	Brain and neural treatments comprising peptides and other compositions
US20140271731A1 (en)	2013-03-13	2014-09-18	Transdermal Biotechnology, Inc.	Cardiovascular disease treatment and prevention
US9387159B2 (en)	2013-03-13	2016-07-12	Transdermal Biotechnology, Inc.	Treatment of skin, including aging skin, to improve appearance
US9393264B2 (en)	2013-03-13	2016-07-19	Transdermal Biotechnology, Inc.	Immune modulation using peptides and other compositions
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2005
- 2005-10-14 DK DK05802312.8T patent/DK1802277T3/da active
- 2005-10-14 AU AU2005296719A patent/AU2005296719B2/en not_active Ceased
- 2005-10-14 KR KR1020077008391A patent/KR101289917B1/ko not_active Expired - Fee Related
- 2005-10-14 NZ NZ554183A patent/NZ554183A/en not_active IP Right Cessation
- 2005-10-14 PL PL05802312T patent/PL1802277T3/pl unknown
- 2005-10-14 DE DE502005008880T patent/DE502005008880D1/de not_active Expired - Lifetime
- 2005-10-14 EA EA200700892A patent/EA011391B1/ru not_active IP Right Cessation
- 2005-10-14 JP JP2007536100A patent/JP5688199B2/ja not_active Expired - Fee Related
- 2005-10-14 WO PCT/EP2005/011054 patent/WO2006042701A1/de not_active Ceased
- 2005-10-14 SI SI200530965T patent/SI1802277T1/sl unknown
- 2005-10-14 US US11/577,488 patent/US8524274B2/en not_active Expired - Fee Related
- 2005-10-14 CN CNA2005800356693A patent/CN101043874A/zh active Pending
- 2005-10-14 PT PT05802312T patent/PT1802277E/pt unknown
- 2005-10-14 AT AT05802312T patent/ATE454884T1/de active
- 2005-10-14 CA CA2583332A patent/CA2583332C/en not_active Expired - Fee Related
- 2005-10-14 EP EP05802312A patent/EP1802277B1/de not_active Expired - Lifetime
- 2005-10-14 ES ES05802312T patent/ES2339577T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE502005008880D1 (de)	2010-03-04
AU2005296719B2 (en)	2011-02-03
ES2339577T3 (es)	2010-05-21
JP2008516911A (ja)	2008-05-22
KR20070069164A (ko)	2007-07-02
EA200700892A1 (ru)	2007-08-31
PT1802277E (pt)	2010-04-01
US8524274B2 (en)	2013-09-03
SI1802277T1 (sl)	2010-05-31
KR101289917B1 (ko)	2013-07-25
AU2005296719A1 (en)	2006-04-27
JP5688199B2 (ja)	2015-03-25
US20090324698A1 (en)	2009-12-31
EP1802277A1 (de)	2007-07-04
CN101043874A (zh)	2007-09-26
PL1802277T3 (pl)	2010-07-30
EP1802277B1 (de)	2010-01-13
EA011391B1 (ru)	2009-02-27
ATE454884T1 (de)	2010-01-15
WO2006042701A1 (de)	2006-04-27
CA2583332C (en)	2013-10-01
CA2583332A1 (en)	2006-04-27
NZ554183A (en)	2009-04-30

Publication	Publication Date	Title
PL1802277T3 (pl)	2010-07-30	Kompozycja liposomowa zawierająca aktywny składnik do rozluźniania mięśni gładkich, otrzymywania tej kompozycji i jej zastosowanie terapeutyczne
PY0228832A (es)	2004-06-01	Formulaciones farmaceuticas de 5,7,14-triazatetra-ciclo [10.3.1.02,11.04,9]-hexadeca-2(11),3,5,7,9-pentaeno
UA90858C2 (ru)	2010-06-10	Композиция с контролируемым высвобождением варденафила
DK1346041T3 (da)	2007-07-02	Terapeutiske midler og fremgangsmåder til anvendelse deraf til behandling af en amyloidogen sygdom
ECSP077185A (es)	2007-02-28	Derivados de piridina
PA8596901A1 (es)	2004-11-26	Inhibidores de p38 y metodos de uso de ellos
UY27740A1 (es)	2003-10-31	Nuevos compuestos
ECSP055701A (es)	2005-05-30	Nuevos derivados de pirimidinamida y el uso de los mismos
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