DK181586A - 2,5-diaryltetrahydrofuran, farmaceutisk praeparat indeholdendeen saadan forbindelse og fremgangsmaade til fremstilling af en saadan forbindelse - Google Patents

2,5-diaryltetrahydrofuran, farmaceutisk praeparat indeholdendeen saadan forbindelse og fremgangsmaade til fremstilling af en saadan forbindelse Download PDF

Info

Publication number: DK181586A
Authority: DK; Denmark
Prior art keywords: connection; diaryltetrahydrofuran; preparing; procedure; pharmaceutical preparation
Prior art date: 1985-04-22

Application number

DK181586A

Other languages

Danish (da)

English (en)

Other versions

DK181586D0 (da

Inventor

Tesfaye Biftu

San-Bao Hwang

Thomas W Doebber

Thomas R Beattie

Tsung-Ying Shen

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-04-22

Filing date

1986-04-21

Publication date

1986-10-23

1986-04-21 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1986-04-21 Publication of DK181586D0 publication Critical patent/DK181586D0/da

1986-10-23 Publication of DK181586A publication Critical patent/DK181586A/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/06—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
- C07D307/08—Preparation of tetrahydrofuran
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/12—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/14—Radicals substituted by nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/16—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/20—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Diabetes (AREA)
Hematology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Furan Compounds (AREA)

DK181586A 1985-04-22 1986-04-21 2,5-diaryltetrahydrofuran, farmaceutisk praeparat indeholdendeen saadan forbindelse og fremgangsmaade til fremstilling af en saadan forbindelse DK181586A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US72568785A	1985-04-22	1985-04-22

Publications (2)

Publication Number	Publication Date
DK181586D0 DK181586D0 (da)	1986-04-21
DK181586A true DK181586A (da)	1986-10-23

Family

ID=24915569

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK181586A DK181586A (da)	1985-04-22	1986-04-21	2,5-diaryltetrahydrofuran, farmaceutisk praeparat indeholdendeen saadan forbindelse og fremgangsmaade til fremstilling af en saadan forbindelse

Country Status (12)

Country	Link
EP (1)	EP0199324B1 (de)
JP (1)	JPS6277A (de)
KR (1)	KR900003372B1 (de)
AU (1)	AU596969B2 (de)
CA (1)	CA1271759A (de)
DE (1)	DE3681751D1 (de)
DK (1)	DK181586A (de)
ES (1)	ES8801909A1 (de)
GR (1)	GR861044B (de)
NZ (1)	NZ215866A (de)
PT (1)	PT82430B (de)
ZA (1)	ZA862961B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5010100A (en) *	1983-11-14	1991-04-23	Merck & Co. Inc.	Certain 2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists
GB2197650A (en) *	1986-11-21	1988-05-25	Merck & Co Inc	Process for preparing 2,5-diphenyl tetrahydrofurans and analogs thereof
NZ227287A (en) *	1987-12-21	1992-01-29	Merck & Co Inc	2,5-diaryl tetrahydrofurans and medicaments
US4996203A (en) *	1987-12-21	1991-02-26	Merck & Co., Inc.	2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists
US5114961A (en) *	1989-06-08	1992-05-19	Merck & Co., Inc.	2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists
US4977146A (en) *	1989-06-08	1990-12-11	Merck & Co., Inc.	2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists
US5001123A (en) *	1989-06-08	1991-03-19	Merck & Co., Inc.	2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists
US5011847A (en) *	1989-06-08	1991-04-30	Merck & Co., Inc.	2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists
GB9009469D0 (en) *	1990-04-27	1990-06-20	British Bio Technology	Compounds
CA2045863A1 (en) *	1990-06-29	1991-12-30	Ichiro Shinkai	Process of making 2,5-diaryl tetrahydrofurans and analogs thereof useful as paf antagonists
US5099033A (en) *	1990-06-29	1992-03-24	Merck & Co., Inc.	Process of making 2,5-diaryl tetrahydrofurans and analogs thereof useful as PAF antagonists
GB9114337D0 (en) *	1991-07-03	1991-08-21	British Bio Technology	Compounds
GB9122308D0 (en) *	1991-10-21	1991-12-04	British Bio Technology	Compounds
US5639782A (en) *	1992-03-04	1997-06-17	Center For Innovative Technology	Neolignan derivatives as platelet activating factor receptor antagonists and 5-lipoxygenase inhibitors
US5358938A (en) *	1992-07-13	1994-10-25	Cytomed, Inc.	Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
US5648486A (en) *	1992-07-13	1997-07-15	Cytomed, Inc.	Compounds and methods for the treatment of inflammatory and immune disorders
US5463083A (en) *	1992-07-13	1995-10-31	Cytomed, Inc.	Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
ATE196903T1 (de) *	1992-07-13	2000-10-15	Cytomed Inc	2,5-diaryl tetrahydro-thiopene, -furane und analoge zur behandlung von entzündungs-und immunkrankheiten
US5434151A (en) *	1992-08-24	1995-07-18	Cytomed, Inc.	Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
US5703093A (en) *	1995-05-31	1997-12-30	Cytomed, Inc.	Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5792776A (en) *	1994-06-27	1998-08-11	Cytomed, Inc.,	Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5750565A (en) *	1995-05-25	1998-05-12	Cytomed, Inc.	Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
KR101965481B1 (ko) *	2016-10-25	2019-04-03	전북대학교산학협력단	쉬겔라 플렉스네리 및 살모넬라 엔터리티디스 검출용 펩타이드

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3769350A (en) *	1968-12-09	1973-10-30	Hoffmann La Roche	Method for making 2,3-dimethyl-1,4-bis(3,4 - hydrocarbonyloxyphenyl) - 1,4-butanedione
US4539332A (en) *	1983-11-14	1985-09-03	Merck & Co., Inc.	2,5-Diaryl tetrahydrofurans and analogs thereof as PAF-antagonists
US4595693A (en) *	1984-06-04	1986-06-17	Merck & Co., Inc.	Method of use of 2,5-diaryl tetrahydrofurans and analogs thereof as PAF-antagonists

1986
- 1986-04-17 NZ NZ215866A patent/NZ215866A/xx unknown
- 1986-04-18 CA CA000507064A patent/CA1271759A/en not_active Expired - Lifetime
- 1986-04-21 AU AU56430/86A patent/AU596969B2/en not_active Ceased
- 1986-04-21 EP EP86105471A patent/EP0199324B1/de not_active Expired - Lifetime
- 1986-04-21 DK DK181586A patent/DK181586A/da not_active Application Discontinuation
- 1986-04-21 ZA ZA862961A patent/ZA862961B/xx unknown
- 1986-04-21 ES ES554214A patent/ES8801909A1/es not_active Expired
- 1986-04-21 GR GR861044A patent/GR861044B/el unknown
- 1986-04-21 DE DE8686105471T patent/DE3681751D1/de not_active Expired - Lifetime
- 1986-04-21 PT PT82430A patent/PT82430B/pt not_active IP Right Cessation
- 1986-04-22 KR KR1019860003097A patent/KR900003372B1/ko not_active Expired
- 1986-04-22 JP JP61091405A patent/JPS6277A/ja active Pending

Also Published As

Publication number	Publication date
DK181586D0 (da)	1986-04-21
GR861044B (en)	1986-08-25
JPS6277A (ja)	1987-01-06
ES554214A0 (es)	1987-08-01
KR900003372B1 (ko)	1990-05-16
AU596969B2 (en)	1990-05-24
EP0199324A3 (en)	1988-02-10
EP0199324B1 (de)	1991-10-02
CA1271759A (en)	1990-07-17
AU5643086A (en)	1986-10-30
KR860008157A (ko)	1986-11-12
ES8801909A1 (es)	1987-08-01
PT82430A (en)	1986-05-01
ZA862961B (en)	1986-12-30
NZ215866A (en)	1989-11-28
EP0199324A2 (de)	1986-10-29
PT82430B (pt)	1988-08-17
DE3681751D1 (de)	1991-11-07

Legal Events

Date	Code	Title	Description
1992-12-28	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
DK181586D0 (da)	1986-04-21	2,5-diaryltetrahydrofuran, farmaceutisk praeparat indeholdende en saadanforbindelse og fremgangsmaade til fremstilling af en saadan forbindelse
DK162445C (da)	1992-03-23	Pyranopyridiner, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende pyranopyridinerne
DK165949C (da)	1993-07-05	1,4-dihydropyridinderivater, fremgangsmaader til fremstilling deraf og farmaceutiske praeparater indeholdende forbindelserne
DK437286D0 (da)	1986-09-12	2,5-diaryl-tetrahydrothiophenforbindelse og fremgangsmaade til fremstilling deraf
DK313086D0 (da)	1986-07-01	Phenoxyalkylisoxazol- eller -furanforbindelse og fremgangsmaade til fremstilling deraf
DK707788D0 (da)	1988-12-20	2,5-diaryltetrahydrofuranforbindelse, praeparat indeholdende en saadan forbindelse og fremgangsmaade til fremstilling af en saadan forbindelse
DK165117C (da)	1993-03-01	1,5-benzothiazepin, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende en saadan forbindelse
DK4189D0 (da)	1989-01-06	Oxadiazolforbindelse, farmaceutisk praeparat indeholdende og fremgangsmaade til fremstilling af forbindelsen
DK162221C (da)	1992-03-02	Cinnolinforbindelser, fremgangsmaade til fremstilling deraf og farmaceutiske midler indeholdende forbindelserne
DK188789A (da)	1989-10-23	N-alkoxy-alkylamidoforbindelse, praeparat indeholdende en saadan forbindelse og fremgangsmaade til fremstilling af en saadan forbindelse
DK91885A (da)	1985-08-30	2,5-diaryltetrahydrothiophen, fremgangsmaade til fremstilling deraf og praeparat indeholdende en saadan forbindelse
DK183986A (da)	1986-10-24	Cyklopentylaetere, fremgangsmaade til fremstilling deraf og laegemiddelpraeparat indeholdende saadanne forbindelser
DK337489D0 (da)	1989-07-07	Spiro-azabicyclisk forbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse samt fremgangsmaade til fremstilling af en saadan forbindelse
DK250090D0 (da)	1990-10-17	Alkylphyosphonoserin, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende en saadan forbindelse
DK160991C (da)	1991-11-11	5,14-dihydrobenzoe5,6aaisoindolooe2,1-baaisoquinolin-8,13-dionderivater, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende en saadan forbindelse
DK634788D0 (da)	1988-11-14	22-deklorteicoplaniner, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende saadanne forbindelser
DK191787A (da)	1987-10-16	Carbapenemforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse
DK495984D0 (da)	1984-10-17	1,3-dihydro-6-methyl-7-hydroxyfuro-(3,4-c)pyridinderivat, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdendeen saadan forbindelse
DK616886D0 (da)	1986-12-19	Optisk aktive 2-klor-12-(3-metylamino-2-metylpropyl)-12h-dibenzo(d,g)(1,3,6)dioxazociner og en fremgangsmaade til fremstilling deraf
DK5785D0 (da)	1985-01-04	Tricycliske forbindelser, fremgangsmaade til fremstilling heraf og farmaceutisk praeparat indeholdende en saadan forbindelse
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