DK1842847T3 - Fremgangsmåde til fremstilling af 5-chlor-2,4-dihydroxypyridin - Google Patents

Fremgangsmåde til fremstilling af 5-chlor-2,4-dihydroxypyridin

Info

Publication number
DK1842847T3
DK1842847T3 DK06712321.6T DK06712321T DK1842847T3 DK 1842847 T3 DK1842847 T3 DK 1842847T3 DK 06712321 T DK06712321 T DK 06712321T DK 1842847 T3 DK1842847 T3 DK 1842847T3
Authority
DK
Denmark
Prior art keywords
dihydroxypyridine
chlor
preparing
Prior art date
Application number
DK06712321.6T
Other languages
English (en)
Inventor
Hiroshi Nagasawa
Katsuyuki Higurashi
Etsuji Yamanaka
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DK1842847T3 publication Critical patent/DK1842847T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/69—Two or more oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
DK06712321.6T 2005-01-26 2006-01-25 Fremgangsmåde til fremstilling af 5-chlor-2,4-dihydroxypyridin DK1842847T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005018100 2005-01-26
PCT/JP2006/301126 WO2006080339A1 (ja) 2005-01-26 2006-01-25 5-クロロ-2,4-ジヒドロキシピリジンの製造方法

Publications (1)

Publication Number Publication Date
DK1842847T3 true DK1842847T3 (da) 2012-04-10

Family

ID=36740369

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06712321.6T DK1842847T3 (da) 2005-01-26 2006-01-25 Fremgangsmåde til fremstilling af 5-chlor-2,4-dihydroxypyridin

Country Status (11)

Country Link
US (1) US7557216B2 (da)
EP (1) EP1842847B1 (da)
JP (1) JP4892472B2 (da)
KR (1) KR101253367B1 (da)
CN (1) CN101107230B (da)
AU (1) AU2006209556B2 (da)
CA (1) CA2594702C (da)
DK (1) DK1842847T3 (da)
ES (1) ES2381800T3 (da)
TW (1) TWI365184B (da)
WO (1) WO2006080339A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101830845A (zh) * 2010-05-28 2010-09-15 南京大唐医药科技有限公司 5-氯-2,3-二羟基吡啶的合成方法
CN103086962A (zh) * 2013-01-25 2013-05-08 苏州昊帆生物科技有限公司 5-氯-2,4-二羟基吡啶的合成方法
CN103408487B (zh) * 2013-08-23 2015-07-08 北京众和民健医药科技有限公司 一种吉莫斯特的精制方法
JP7070938B2 (ja) * 2020-03-31 2022-05-18 白鳥製薬株式会社 ハロヒドロキシ芳香族化合物の製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5248670A (en) * 1975-10-17 1977-04-18 Nippon Shinyaku Co Ltd Preparation of 2,5-disubstituted-pyridine derivatives
DE3585869D1 (de) * 1984-10-30 1992-05-21 Otsuka Pharma Co Ltd Zusammensetzung zur steigerung der antikrebsaktivitaet einer antikrebsverbindung.
JPS62155215A (ja) * 1984-11-30 1987-07-10 Otsuka Pharmaceut Co Ltd 抗腫瘍活性増強剤
JP2805114B2 (ja) * 1991-08-05 1998-09-30 大鵬薬品工業株式会社 α,β−不飽和ケトエステル誘導体
JP2826646B2 (ja) * 1991-09-19 1998-11-18 大鵬薬品工業株式会社 3−置換−5−ハロゲノピリジン誘導体

Also Published As

Publication number Publication date
CA2594702C (en) 2012-10-02
HK1113930A1 (en) 2008-10-17
EP1842847A1 (en) 2007-10-10
CN101107230B (zh) 2010-05-19
CN101107230A (zh) 2008-01-16
KR101253367B1 (ko) 2013-04-11
TW200637825A (en) 2006-11-01
EP1842847A4 (en) 2011-01-19
WO2006080339A1 (ja) 2006-08-03
CA2594702A1 (en) 2006-08-03
ES2381800T3 (es) 2012-05-31
KR20070095973A (ko) 2007-10-01
JP4892472B2 (ja) 2012-03-07
US7557216B2 (en) 2009-07-07
AU2006209556B2 (en) 2010-12-02
TWI365184B (en) 2012-06-01
JPWO2006080339A1 (ja) 2008-06-19
EP1842847B1 (en) 2012-03-07
AU2006209556A1 (en) 2006-08-03
US20090043101A1 (en) 2009-02-12

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