DK185283A - Tricycliske forbindelser, deres fremstilling og anvendelse, samt mellemprodukter herfor - Google Patents

Tricycliske forbindelser, deres fremstilling og anvendelse, samt mellemprodukter herfor Download PDF

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Publication number
DK185283A
DK185283A DK185283A DK185283A DK185283A DK 185283 A DK185283 A DK 185283A DK 185283 A DK185283 A DK 185283A DK 185283 A DK185283 A DK 185283A DK 185283 A DK185283 A DK 185283A
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DK
Denmark
Prior art keywords
tricyclic
intermediates
relationships
production
compounds
Prior art date
Application number
DK185283A
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English (en)
Other versions
DK185283D0 (da
Inventor
John Frederick Batchelor
Richard Martin Hyde
William Richard King
David John Livingstone
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of DK185283D0 publication Critical patent/DK185283D0/da
Publication of DK185283A publication Critical patent/DK185283A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
    • C07D311/86—Oxygen atoms, e.g. xanthones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Description

er ro altid større end 1, og intet enkelt carbonatoro i gruppen -(CmH2m)- er knyttet til to oxygenatomer, eller salte heraf, fremstilles ved en række forskellige fremgangsmåder .
Forbindelserne er værdifulde i medicinen under omstændigheder, hvor det er ønskeligt at tilvejebringe en mere effektiv levering af oxygen til vævene. In-vivo-anvendel-ser er bl.a. lindring og bedring af vævshypoxi, f.eks. ved cardial eller cerebral iskæmi, medens forbindelserne in vitro opretholder oxygenleveringskapaciteten af oplagrede røde blodlegemer og forlænger blodlegemernes nyttige lagerlevetid.
En steril, tæt tillukket beholder, der indeholder «1 an-tikoagulant og en af de ovennævnte forbindelser, samt indeholder eller påfyldes humane erythrocyter, tjener til opbevaring af erythrocyterne med henblik på transfusion.
DK185283A 1982-04-27 1983-04-26 Tricycliske forbindelser, deres fremstilling og anvendelse, samt mellemprodukter herfor DK185283A (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8212139 1982-04-27
GB8212139 1982-04-27
GB8230055 1982-10-21
GB8230055 1982-10-21

Publications (2)

Publication Number Publication Date
DK185283D0 DK185283D0 (da) 1983-04-26
DK185283A true DK185283A (da) 1983-10-28

Family

ID=26282657

Family Applications (1)

Application Number Title Priority Date Filing Date
DK185283A DK185283A (da) 1982-04-27 1983-04-26 Tricycliske forbindelser, deres fremstilling og anvendelse, samt mellemprodukter herfor

Country Status (11)

Country Link
US (1) US4902701A (da)
EP (1) EP0093381B1 (da)
AU (1) AU566167B2 (da)
CA (1) CA1222516A (da)
DE (1) DE3364674D1 (da)
DK (1) DK185283A (da)
FI (1) FI82832C (da)
GR (1) GR78142B (da)
IE (1) IE55228B1 (da)
IL (1) IL68498A (da)
NZ (1) NZ204003A (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8309260D0 (en) * 1983-04-06 1983-05-11 Erba Farmitalia Condensed benzopyrone derivatives
GB8328494D0 (en) * 1983-10-25 1983-11-23 Wellcome Found Liquid containment systems
US4861795A (en) * 1988-06-23 1989-08-29 Rorer Pharmaceutical Corporation Treatment of conditions requiring enhanced oxygen availability to mammalian tissues
US4849416A (en) * 1988-07-25 1989-07-18 Rorer Pharmaceutical Corporation Treatment of conditions requiring enhanced oxygen availability to mammalian tissues
US4996230A (en) * 1990-02-16 1991-02-26 Eli Lilly And Company Leukotriene antagonists
IT1261662B (it) * 1992-09-07 1996-05-28 Inverni Della Beffa Spa Derivati xantonici, loro preparazione ed attivita'
US5624794A (en) * 1995-06-05 1997-04-29 The Regents Of The University Of California Method for extending the useful shelf-life of refrigerated red blood cells by flushing with inert gas
US5977077A (en) * 1995-08-28 1999-11-02 Interlab Corporation Xanthone analogs for the treatment of infectious diseases
EP0795554A3 (en) * 1996-03-05 1998-01-28 Takeda Chemical Industries, Ltd. (Oxo-)xanthene derivatives, their preparation and their use as immunomodulators
US6355153B1 (en) * 1999-09-17 2002-03-12 Nutool, Inc. Chip interconnect and packaging deposition methods and structures
US7506438B1 (en) * 2000-11-14 2009-03-24 Freescale Semiconductor, Inc. Low profile integrated module interconnects and method of fabrication
US8828226B2 (en) 2003-03-01 2014-09-09 The Trustees Of Boston University System for assessing the efficacy of stored red blood cells using microvascular networks
CN102905522A (zh) 2009-10-12 2013-01-30 新健康科学股份有限公司 用于从红细胞中除去氧的氧消耗装置和方法
US12089589B2 (en) 2009-10-12 2024-09-17 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US11284616B2 (en) 2010-05-05 2022-03-29 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US9199016B2 (en) 2009-10-12 2015-12-01 New Health Sciences, Inc. System for extended storage of red blood cells and methods of use
BR112012008683B8 (pt) 2009-10-12 2022-11-08 Hemanext Inc dispositivo de armazenagem de sangue para armazenar sangue depletado de oxigênio e dióxido de carbono, dispositivo de depleção de oxigênio e dióxido de carbono, método para remover oxigênio e dióxido de carbono de hemácias, sistema de armazenagem de sangue, dispositivo de armazenagem de sangue, método para remover oxigênio de hemácias e método para aumentar os níveis de adenosina trifosfato (atp) nas hemácias
WO2012027582A1 (en) 2010-08-25 2012-03-01 New Health Sciences Method for enhancing red blood cell quality and survival during storage
EP4218412A1 (en) 2010-11-05 2023-08-02 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US9067004B2 (en) 2011-03-28 2015-06-30 New Health Sciences, Inc. Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly
AU2012294269B2 (en) 2011-08-10 2016-11-24 Hemanext Inc. Integrated leukocyte, oxygen and/or CO2 depletion, and plasma separation filter device
CA2902061C (en) 2013-02-28 2023-08-08 New Health Sciences, Inc. Gas depletion and gas addition devices for blood treatment
KR20250033333A (ko) 2015-03-10 2025-03-07 헤마넥스트 인코포레이티드 산소 감소 1회용 키트, 장치 및 이의 사용 방법
BR122022005103B1 (pt) 2015-04-23 2023-03-14 Hemanext Inc Dispositivo de armazenamento de sangue para armazenar sangue depletado de oxigênio e método para armazenar sangue depletado de oxigênio
PT3297641T (pt) 2015-05-18 2025-10-09 Hemanext Inc Métodos de armazenamento de sangue total e respetivas composições
CN109195632A (zh) 2016-05-27 2019-01-11 新健康科学股份有限公司 厌氧血液储存和病原体失活方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2783246A (en) * 1955-05-02 1957-02-26 Allied Chem & Dye Corp Manufacture of xanthene
BE759292A (fr) * 1969-11-27 1971-05-24 Allen & Hanburys Ltd Derives de xanthone, leur preparation et leur emploi
US4061768A (en) * 1971-09-08 1977-12-06 Burroughs Wellcome Co. Certain cyclic carbonyl compounds used in the prophylaxis of allergic conditions
AU478775B2 (en) * 1974-09-13 1974-12-12 Syntex Gu. S. A. ) Inc Novel substituted xanthone carboxylic acid compounds

Also Published As

Publication number Publication date
GR78142B (da) 1984-09-26
DK185283D0 (da) 1983-04-26
IE55228B1 (en) 1990-07-04
US4902701A (en) 1990-02-20
IL68498A0 (en) 1983-07-31
FI82832C (fi) 1991-04-25
DE3364674D1 (en) 1986-08-28
NZ204003A (en) 1986-05-09
FI831420L (fi) 1983-10-28
IL68498A (en) 1986-09-30
IE830949L (en) 1983-10-27
AU1392483A (en) 1983-11-03
FI831420A0 (fi) 1983-04-26
EP0093381B1 (en) 1986-07-23
FI82832B (fi) 1991-01-15
CA1222516A (en) 1987-06-02
AU566167B2 (en) 1987-10-08
EP0093381A1 (en) 1983-11-09

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