DK187889A - Dna-forbindelser og klonende vektorer, der koder for det monoklonale antistof ks1/4, samt chimere antistoffer afledt af ks1/4 og rettet mod et humant adenocarcinoma-antigen - Google Patents

Dna-forbindelser og klonende vektorer, der koder for det monoklonale antistof ks1/4, samt chimere antistoffer afledt af ks1/4 og rettet mod et humant adenocarcinoma-antigen

Info

Publication number
DK187889A
DK187889A DK187889A DK187889A DK187889A DK 187889 A DK187889 A DK 187889A DK 187889 A DK187889 A DK 187889A DK 187889 A DK187889 A DK 187889A DK 187889 A DK187889 A DK 187889A
Authority
DK
Denmark
Prior art keywords
chimerary
directed
monoclonal antibody
cloning vectors
antibodies derived
Prior art date
Application number
DK187889A
Other languages
Danish (da)
English (en)
Other versions
DK187889D0 (da
Inventor
Lisa Selsam Beavers
Thomas Frank Bumol
Robert Alan Gadski
Barbara Jean Weigel
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK187889D0 publication Critical patent/DK187889D0/da
Publication of DK187889A publication Critical patent/DK187889A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/462—Igs containing a variable region (Fv) from one specie and a constant region (Fc) from another
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/867—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving immunoglobulin or antibody produced via recombinant dna technology

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK187889A 1988-04-21 1989-04-19 Dna-forbindelser og klonende vektorer, der koder for det monoklonale antistof ks1/4, samt chimere antistoffer afledt af ks1/4 og rettet mod et humant adenocarcinoma-antigen DK187889A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/184,522 US4975369A (en) 1988-04-21 1988-04-21 Recombinant and chimeric KS1/4 antibodies directed against a human adenocarcinoma antigen

Publications (2)

Publication Number Publication Date
DK187889D0 DK187889D0 (da) 1989-04-19
DK187889A true DK187889A (da) 1989-10-23

Family

ID=22677247

Family Applications (1)

Application Number Title Priority Date Filing Date
DK187889A DK187889A (da) 1988-04-21 1989-04-19 Dna-forbindelser og klonende vektorer, der koder for det monoklonale antistof ks1/4, samt chimere antistoffer afledt af ks1/4 og rettet mod et humant adenocarcinoma-antigen

Country Status (14)

Country Link
US (1) US4975369A (de)
EP (1) EP0338767A3 (de)
JP (1) JPH02211877A (de)
KR (1) KR900016459A (de)
CN (1) CN1037174A (de)
AU (1) AU621600B2 (de)
DK (1) DK187889A (de)
HU (1) HUT50870A (de)
IL (1) IL90016A0 (de)
NZ (1) NZ228801A (de)
PH (1) PH26945A (de)
PT (1) PT90312A (de)
RU (1) RU1780541C (de)
ZA (1) ZA892840B (de)

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EP0245949B1 (de) * 1986-04-09 1997-10-29 Eli Lilly And Company Verfahren zur Anwendung von den BK-Virus-Verstärker enthaltenden eukaryotischen Expressionsvektoren
CA1340456C (en) * 1986-07-07 1999-03-23 Hubert J.P. Schoemaker Chimeric rodent/human immunoglobulins specific for tumor-associated antigens

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EP0338767A2 (de) 1989-10-25
HUT50870A (en) 1990-03-28
AU621600B2 (en) 1992-03-19
AU3318989A (en) 1989-10-26
IL90016A0 (en) 1989-12-15
NZ228801A (en) 1991-05-28
EP0338767A3 (de) 1991-07-17
CN1037174A (zh) 1989-11-15
PT90312A (pt) 1989-11-10
DK187889D0 (da) 1989-04-19
RU1780541C (ru) 1992-12-07
JPH02211877A (ja) 1990-08-23
US4975369A (en) 1990-12-04
KR900016459A (ko) 1990-11-13
ZA892840B (en) 1990-12-28
PH26945A (en) 1992-12-03

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