DK190287A - Monoklonale antistoffer til human-interleukin-2-receptor samt hybridcellelinier til fremstilling deraf - Google Patents

Monoklonale antistoffer til human-interleukin-2-receptor samt hybridcellelinier til fremstilling deraf

Info

Publication number
DK190287A
DK190287A DK190287A DK190287A DK190287A DK 190287 A DK190287 A DK 190287A DK 190287 A DK190287 A DK 190287A DK 190287 A DK190287 A DK 190287A DK 190287 A DK190287 A DK 190287A
Authority
DK
Denmark
Prior art keywords
human
interleukin
cell lines
antibody
hybrid cell
Prior art date
Application number
DK190287A
Other languages
Danish (da)
English (en)
Other versions
DK190287D0 (da
Inventor
Tibor Diamantstein
Hisao Osawa
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10596154&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK190287(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK190287D0 publication Critical patent/DK190287D0/da
Publication of DK190287A publication Critical patent/DK190287A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK190287A 1986-04-14 1987-04-13 Monoklonale antistoffer til human-interleukin-2-receptor samt hybridcellelinier til fremstilling deraf DK190287A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8609058A GB2188941B (en) 1986-04-14 1986-04-14 Monoclonal antibodies recognizing human interleukin-2-receptor

Publications (2)

Publication Number Publication Date
DK190287D0 DK190287D0 (da) 1987-04-13
DK190287A true DK190287A (da) 1987-10-15

Family

ID=10596154

Family Applications (1)

Application Number Title Priority Date Filing Date
DK190287A DK190287A (da) 1986-04-14 1987-04-13 Monoklonale antistoffer til human-interleukin-2-receptor samt hybridcellelinier til fremstilling deraf

Country Status (8)

Country Link
US (1) US5631349A (fr)
EP (1) EP0241811B1 (fr)
JP (1) JPS6312297A (fr)
AT (1) ATE97816T1 (fr)
DE (1) DE3788296D1 (fr)
DK (1) DK190287A (fr)
ES (1) ES2060581T3 (fr)
GB (1) GB2188941B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3855236D1 (de) * 1987-08-17 1996-05-30 Us Commerce Verfahren zur behandlung der bösartigen und autoimmunen krankheiten beim menschen
WO1989009622A1 (fr) * 1988-04-15 1989-10-19 Protein Design Labs, Inc. Anticorps chimeriques specifiques au recepteur il-2
DE3815472A1 (de) * 1988-05-06 1989-11-16 Centre Regional De Transfusion Monoklonaler antikoerper und seine verwendung
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
IL162181A (en) * 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
PT92900A (pt) * 1989-01-24 1990-07-31 Sistema de vectores de expressao para a producao de anticorpos monoclonais quimericos
FR2649488A1 (fr) * 1989-07-07 1991-01-11 Inst Nat Sante Rech Med Fragments d'anticorps monoclonaux specifiques de la presence de leucocytes actives - leur procede d'obtention et leur application dans le cas de rejet de greffe
FR2652746A1 (fr) * 1989-10-06 1991-04-12 Merieux Inst Application d'agents actifs pour la preparation d'un medicament destine au traitement de lymphomes ou assimiles.
FR2652747B1 (fr) * 1989-10-06 1995-03-31 Merieux Inst Application d'agents actifs pour la preparation d'un medicament destine au traitement de maladies auto-immunes.
HUT60768A (en) 1990-03-16 1992-10-28 Sandoz Ag Process for producing cd25 fixing molecules
DE4028955A1 (de) * 1990-09-12 1992-03-19 Boehringer Mannheim Gmbh Monoklonale antikoerper gegen den interleukin 2-rezeptor
FR2672291A1 (fr) * 1991-01-31 1992-08-07 Inst Nat Sante Rech Med Composition d'anticorps diriges contre le recepteur de l'interleukine-2 humaine ou animale.
EP1400536A1 (fr) 1991-06-14 2004-03-24 Genentech Inc. Procédé pour fabriquer des anticorps humanisés
WO1994004679A1 (fr) * 1991-06-14 1994-03-03 Genentech, Inc. Procede pour fabriquer des anticorps humanises
US6800738B1 (en) 1991-06-14 2004-10-05 Genentech, Inc. Method for making humanized antibodies
CA2443405A1 (fr) * 2001-04-06 2002-10-17 University Of Bristol Utilisation de molecules de liaison cd25 chez des patients resistants aux steroides
AU2002368055B2 (en) * 2002-06-28 2008-09-18 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Method of treating autoimmune diseases with interferon-beta and IL-2R antagonist

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4411993A (en) * 1981-04-29 1983-10-25 Steven Gillis Hybridoma antibody which inhibits interleukin 2 activity
US4578335A (en) * 1984-05-21 1986-03-25 Immunex Corporation Interleukin 2 receptor
US4845198A (en) * 1984-05-21 1989-07-04 Immunex Corporation Hybridoma antibody which binds IL-2 receptor
JPS6147500A (ja) * 1984-08-15 1986-03-07 Res Dev Corp Of Japan キメラモノクロ−ナル抗体及びその製造法
GB8422238D0 (en) * 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
US4707443A (en) * 1985-04-19 1987-11-17 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Soluble interleukin-2 receptor as a disease indicator and a method of assaying the same
DE3628718A1 (de) * 1985-12-03 1987-06-04 Bayer Ag Geloeste interleukin-2-rezeptoren als indikator fuer immunreaktionen und neoplasien
GB8605316D0 (en) * 1986-03-04 1986-04-09 Royal Free Hosp School Med Immunosuppression

Also Published As

Publication number Publication date
US5631349A (en) 1997-05-20
DE3788296D1 (de) 1994-01-13
GB2188941A (en) 1987-10-14
GB8609058D0 (en) 1986-05-21
EP0241811A3 (en) 1989-07-26
JPS6312297A (ja) 1988-01-19
EP0241811B1 (fr) 1993-12-01
GB2188941B (en) 1990-06-06
ATE97816T1 (de) 1993-12-15
EP0241811A2 (fr) 1987-10-21
ES2060581T3 (es) 1994-12-01
DK190287D0 (da) 1987-04-13

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment