DK1906972T3 - LPA2-receptoragonist til behandling af diarré - Google Patents

LPA2-receptoragonist til behandling af diarré

Info

Publication number
DK1906972T3
DK1906972T3 DK06787646.6T DK06787646T DK1906972T3 DK 1906972 T3 DK1906972 T3 DK 1906972T3 DK 06787646 T DK06787646 T DK 06787646T DK 1906972 T3 DK1906972 T3 DK 1906972T3
Authority
DK
Denmark
Prior art keywords
diarrhea
treatment
receptor agonist
lpa2 receptor
lpa2
Prior art date
Application number
DK06787646.6T
Other languages
English (en)
Inventor
Chunying Li
Wenlin Deng
Anjaparavanda Naren
Leonard Johnson
Gangadhar Durgam
Duane Miller
Gabor Tigyi
Original Assignee
Univ Tennessee Res Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Tennessee Res Foundation filed Critical Univ Tennessee Res Foundation
Application granted granted Critical
Publication of DK1906972T3 publication Critical patent/DK1906972T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
DK06787646.6T 2005-07-19 2006-07-19 LPA2-receptoragonist til behandling af diarré DK1906972T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70048905P 2005-07-19 2005-07-19
PCT/US2006/027765 WO2007011905A2 (en) 2005-07-19 2006-07-19 Lpa2 receptor agonist inhibitors of cftr

Publications (1)

Publication Number Publication Date
DK1906972T3 true DK1906972T3 (da) 2013-12-16

Family

ID=37669488

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06787646.6T DK1906972T3 (da) 2005-07-19 2006-07-19 LPA2-receptoragonist til behandling af diarré

Country Status (8)

Country Link
US (1) US20070078111A1 (da)
EP (1) EP1906972B1 (da)
JP (1) JP2009502790A (da)
AU (1) AU2006270066A1 (da)
CA (1) CA2615836A1 (da)
DK (1) DK1906972T3 (da)
IL (1) IL188820A0 (da)
WO (1) WO2007011905A2 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008140574A2 (en) 2006-11-15 2008-11-20 University Of Tennessee Research Foundation Radiation protection and treatment for exposure to gamma-radiation
EP2767541A1 (en) * 2008-03-03 2014-08-20 Rxbio, Inc. LPA receptor agonists and antagonists
CA2844982A1 (en) 2011-08-15 2013-02-21 Intermune, Inc. Lysophosphatidic acid receptor antagonists
US20140206714A1 (en) * 2012-08-27 2014-07-24 University Of Tennessee Research Foundation Lpa2 receptor-specific benzoic acid derivatives
KR102580225B1 (ko) 2013-06-11 2023-09-20 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 SC-β 세포 및 조성물 그리고 그 생성 방법
EP3089986B1 (en) 2013-12-30 2019-06-26 Rxbio Inc. Crystalline salts of (z)-o-octadec-9-en-1-yl o,o-dihydrogen phosphorothioate
US10449210B2 (en) * 2014-02-13 2019-10-22 Ligand Pharmaceuticals Inc. Prodrug compounds and their uses
CN111788196A (zh) 2018-01-09 2020-10-16 配体药物公司 缩醛化合物及其治疗用途
CN116725126A (zh) * 2023-07-07 2023-09-12 四川农业大学 溶血磷脂酸在防治猪感染性腹泻中的应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3854480A (en) 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
US3832253A (en) 1973-03-21 1974-08-27 Baxter Laboratories Inc Method of making an inflatable balloon catheter
US4667014A (en) 1983-03-07 1987-05-19 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH, useful as LHRH antagonists
US4452775A (en) 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
CA1200416A (en) 1983-05-13 1986-02-11 Societe Des Produits Nestle S.A. Food process
US4663166A (en) * 1984-06-22 1987-05-05 Veech Richard L Electrolyte solutions and in vivo use thereof
JPH04167172A (ja) 1990-10-31 1992-06-15 Nec Corp ベクトルプロセッサ
US6495532B1 (en) * 1997-03-19 2002-12-17 Sky High, Llc Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof
EP1069895A4 (en) * 1998-03-18 2002-07-31 Lxr Biotechnology Inc COMPOSITIONS CONTAINING LYSOPHOSPHATIDE ACIDS THAT INHIBIT APOPTOSIS AND USES THEREOF
DK1263752T3 (da) 2000-03-17 2008-04-14 Univ Tennessee Res Corp LPA-receptoragonister og -antagonister og fremgangsmåde til anvendelse heraf
US20030130237A1 (en) * 2000-03-17 2003-07-10 Miller Duane D. LPA receptor agonists and antagonists and methods of use
US7235573B2 (en) * 2002-09-30 2007-06-26 The Regents Of The University Of California Methods of treating secretory diarrhea using cystic fibrosis transmembrane conductance regulator protein inhibitors
AU2004278042B2 (en) * 2003-10-09 2012-02-09 University Of Tennessee Research Foundation LPA receptor agonists and antagonists and methods of use

Also Published As

Publication number Publication date
AU2006270066A1 (en) 2007-01-25
EP1906972A4 (en) 2010-10-06
US20070078111A1 (en) 2007-04-05
WO2007011905A2 (en) 2007-01-25
JP2009502790A (ja) 2009-01-29
CA2615836A1 (en) 2007-01-25
EP1906972B1 (en) 2013-09-11
EP1906972A2 (en) 2008-04-09
IL188820A0 (en) 2008-12-29
WO2007011905A3 (en) 2007-11-01

Similar Documents

Publication Publication Date Title
DK1973888T3 (da) Isoxazoliner til bekæmpelse af hvirvelløse skadedyr
EP2015752A4 (en) P13 Kinase Antagonists
DK1893586T3 (da) Fremgangsmåde til fremstilling af 1-alkyl-3-phenyluraciler
DK1907373T3 (da) Fremgangsmåder til fremstillingen af 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindolin-1,3-dionforbindelser
DK1877232T3 (da) Fremgangsmåde til behandling af træoverflader
DK1863833T3 (da) Fremgangsmåde til fremstilling af makrocykliske forbindelser
DK1737461T3 (da) Carbolin-derivater til inhibering af angiogenese
DK1828164T3 (da) Fremgangsmåde til fremstilling af N-phenylpyrazol-1-carboxamider
DK2139390T3 (da) Fremgangsmåde til evaluering af effektiviteten af kommerciel kommunikation
DK1778668T3 (da) Fremgangsmåde til fremstilling af dihydropteridion
EP2028692A4 (en) Semiconductor device
EP1951684A4 (en) BIARYLMETAPYRIMIDINKINASEINHIBITOREN
DK1984345T3 (da) Benzoxaziner og beslægtede nitrogenholdige heterobicykliske forbindelser, der kan anvendes som mineralcorticoidreceptormodulerende midler
DK1979356T3 (da) Carbonylaminopyrrolopyrazoler, kraftige kinaseinhibitorer
EP2079466A4 (en) SUBSTITUTED INDOLE COMPOUNDS
DK1852430T3 (da) Fremgangsmåde til fremstilling af proanthocyanidinoligomer
DK1725819T3 (da) Adaptiv fremgangsmåde til afrimning
DK3403657T3 (da) Anvendelse af oligouronater til behandling af slimhyperviskositet
DE602006019852D1 (de) Verriegelungsspannfutter
ATE549350T1 (de) Neuropeptid-2-rezeptor-agonisten
DK1948176T3 (da) Diarylurinstoffer til behandling af pulmonær hypertension
DK1973886T3 (da) Prokineticin-1-receptor-antagonister
DE112005003586A5 (de) Bohrfutter
EP1934716A4 (en) COMPONENT ARCHITECTURE
DK1773787T3 (da) Fremgangsmåde til fremstilling af 3-phenyl(thio)uraciler og -dithiouraciler