DK1928438T3 - Anvendelse af ibudilast til behandling af stofafhængighed - Google Patents

Anvendelse af ibudilast til behandling af stofafhængighed

Info

Publication number
DK1928438T3
DK1928438T3 DK06815512.6T DK06815512T DK1928438T3 DK 1928438 T3 DK1928438 T3 DK 1928438T3 DK 06815512 T DK06815512 T DK 06815512T DK 1928438 T3 DK1928438 T3 DK 1928438T3
Authority
DK
Denmark
Prior art keywords
ibudilast
treatment
drug dependence
dependence
drug
Prior art date
Application number
DK06815512.6T
Other languages
English (en)
Inventor
Kirk W Johnson
Linda May Rothblum Watkins
Original Assignee
Avigen Inc
Univ Colorado
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avigen Inc, Univ Colorado filed Critical Avigen Inc
Application granted granted Critical
Publication of DK1928438T3 publication Critical patent/DK1928438T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK06815512.6T 2005-09-26 2006-09-26 Anvendelse af ibudilast til behandling af stofafhængighed DK1928438T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72056805P 2005-09-26 2005-09-26
US81003806P 2006-05-31 2006-05-31
PCT/US2006/037563 WO2007038551A2 (en) 2005-09-26 2006-09-26 Use of ibudilast for treating drug and behavioral addictions

Publications (1)

Publication Number Publication Date
DK1928438T3 true DK1928438T3 (da) 2013-04-22

Family

ID=37806904

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06815512.6T DK1928438T3 (da) 2005-09-26 2006-09-26 Anvendelse af ibudilast til behandling af stofafhængighed

Country Status (12)

Country Link
US (1) US7915285B2 (da)
EP (1) EP1928438B1 (da)
JP (1) JP5411504B2 (da)
AU (1) AU2006294758A1 (da)
BR (1) BRPI0616344A2 (da)
CA (1) CA2623072A1 (da)
DK (1) DK1928438T3 (da)
ES (1) ES2412858T3 (da)
PL (1) PL1928438T3 (da)
PT (1) PT1928438E (da)
RU (1) RU2008116720A (da)
WO (1) WO2007038551A2 (da)

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* Cited by examiner, † Cited by third party
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PT1928438E (pt) 2005-09-26 2013-04-03 Avigen Inc Método para tratamento de dependências de drogas e comportamentos
US20110275664A1 (en) * 2005-09-26 2011-11-10 The Regents Of The University Of Colorado,A Body Corporate Method for treating drug and behavioral addictions
WO2007142924A1 (en) * 2006-05-31 2007-12-13 Avigen, Inc. Ibudilast for inhibiting macrophage migration inhibitory factor (mif) activity
US20070281924A1 (en) * 2006-05-31 2007-12-06 Gaeta Federico C MIF inhibitors for treating neuropathic pain and associated syndromes
EP2073813A2 (en) * 2006-10-10 2009-07-01 The University of Chicago Composition s comprising a benzodiazepine, an alcohol aversive agent and an abuse aversive agent
CA2669463A1 (en) * 2006-11-09 2008-05-15 Avigen, Inc. Method for treating delirium
JP2010513569A (ja) * 2006-12-19 2010-04-30 ユニバーシティ オブ バージニア パテント ファウンデーション アルコール摂取に対するトピラメートおよびオンダンセトロンの併用効果
EP2131841B1 (en) * 2007-01-30 2012-08-01 Avigen, Inc. Methods for treating acute pain
US20100076006A1 (en) * 2007-01-31 2010-03-25 University Of Virginia Patent Foundation Topiramate Plus Naltrexone for the Treatment of Addictive Disorders
US8637528B2 (en) 2007-03-27 2014-01-28 Omeros Corporation Use of PDE7 inhibitors for the treatment of movement disorders
WO2008137012A1 (en) * 2007-05-03 2008-11-13 Avigen, Inc. Use of a glial attenuator to prevent amplified pain responses caused by glial priming
US20090028816A1 (en) * 2007-07-27 2009-01-29 Lance Sultzbaugh Treatment of depression, psychosis, and anxiety
WO2009029308A1 (en) * 2007-08-27 2009-03-05 University Of Virginia Patent Foundation Medication combinations for the treatment of alcoholism and drug addiction
ES2430940T3 (es) 2008-02-28 2013-11-22 University Of Virginia Patent Foundation Gen del transportador de serotonina y tratamiento del alcoholismo
CN102307895A (zh) * 2008-12-04 2012-01-04 里兰斯坦福初级大学理事会 用于治疗或预防麻醉药停药症状的方法和组合物
US8202525B2 (en) * 2009-12-22 2012-06-19 Pondera Biotechnologies, LLC Methods and compositions for treating distress dysfunction and enhancing safety and efficacy of specific medications
US20110218215A1 (en) * 2010-03-04 2011-09-08 Holly Benjamin D Compositions and Methods for Treating Social Anxiety
HUE035574T2 (en) 2010-07-02 2018-05-28 Univ Virginia Patent Foundation Molecular genetic approach to treatment and diagnosis of alcohol and drug dependence
US9220715B2 (en) 2010-11-08 2015-12-29 Omeros Corporation Treatment of addiction and impulse-control disorders using PDE7 inhibitors
KR20130124333A (ko) 2010-11-08 2013-11-13 오메로스 코포레이션 Pde7 억제제를 사용한 중독 및 충동-조절 장애의 치료
AU2013201989B2 (en) * 2010-11-08 2016-01-07 Omeros Corporation Treatment of addiction and impulse-control disorders using PDE7 inhibitors
CA2845039A1 (en) * 2011-08-18 2013-02-21 Shire Ag Combinations of a 5-ht4 receptor agonist and a pde4 inhibitor for use in therapy
US20130096173A1 (en) 2011-09-09 2013-04-18 Bankole A. Johnson Molecular genetic approach to treatment and diagnosis of alcohol and drug dependence
US9610285B2 (en) 2011-11-16 2017-04-04 University Of Florida Research Foundation, Incorporated Compositions for controlling food intake and uses therefor
LT2846805T (lt) * 2012-05-07 2019-02-25 Omeros Corporation Priklausomybių ir impulsų kontrolės sutrikimų gydymas, panaudojant pde7 inhibitorius
EP2846805B1 (en) * 2012-05-07 2018-11-21 Omeros Corporation Treatment of addiction and impulse-control disorders using pde7 inhibitors
US20150051191A1 (en) * 2013-08-15 2015-02-19 Medicinova, Inc. Treatment of alcoholism using ibudilast
EP3082816B1 (en) 2013-12-20 2019-03-20 Indivior UK Limited Intranasal naloxone compositions and methods of making and using same
US10188645B2 (en) * 2015-08-26 2019-01-29 Ian Cain Smith Methods and compositions for ameliorating symptoms of termination of opioid pain therapy
WO2017196857A1 (en) * 2016-05-10 2017-11-16 Medicinova, Inc. Treatment of alcoholism and depression and/or dysphoric mood using ibudilast
US20190201494A1 (en) * 2016-09-13 2019-07-04 Stc Unm Compositions and methods for treating nicotine withdrawal
US11129803B2 (en) 2017-09-18 2021-09-28 SEN-JAM Pharmaceutical LLC Methods and compositions to inhibit tolerance to opioids
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same
US12303604B1 (en) 2024-10-16 2025-05-20 Currax Pharmaceuticals Llc Pharmaceutical formulations comprising naltrexone and/or bupropion

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JP3601898B2 (ja) * 1996-02-14 2004-12-15 俊隆 鍋島 薬物依存形成抑制剤
AU4543899A (en) 1998-06-08 1999-12-30 Advanced Medicine, Inc. Multibinding inhibitors of microsomal triglyceride transferase protein
US6057368A (en) * 1998-08-05 2000-05-02 Brookhaven Science Associates Llc Treatment of addiction and addiction-related behavior
FR2797402B1 (fr) * 1999-07-15 2004-03-12 Biomerieux Stelhys Utilisation d'un polypeptide pour detecter, prevenir ou traiter un etat pathologique associe a une maladie degenerative, neurologique ou autoimmune
US6953774B2 (en) * 2000-08-11 2005-10-11 Applied Research Systems Ars Holding N.V. Methods of inducing ovulation
UY27304A1 (es) 2001-05-24 2002-12-31 Avanir Pharmaceuticals Inhibidores del factor inhibidor de la migración de los macrófagos y métodos para su identificación
US20060106102A1 (en) 2002-06-07 2006-05-18 Eric Morand Napththalene derivatives which inhibit the cytokine or biological activity of microphage migration inhibitory factor (mif)
NZ537301A (en) 2002-06-07 2006-06-30 Cortical Pty Ltd Therapeutic molecules and methods-1
JP4589122B2 (ja) * 2002-12-03 2010-12-01 杏林製薬株式会社 ホスホジエステラーゼ10a阻害剤
US7125997B2 (en) 2002-12-20 2006-10-24 Irm Llc Differential tumor cytotoxicity compounds and compositions
US7261882B2 (en) 2003-06-23 2007-08-28 Reagents Of The University Of Colorado Methods for treating neuropathic pain by administering IL-10 polypeptides
WO2005058304A1 (en) 2003-12-17 2005-06-30 Cortical Pty Ltd Implantable device containing inhibitor of macrophage migration inhibitory factor
GB0423405D0 (en) 2004-10-21 2004-11-24 Novartis Ag Organic compounds
MX2007006777A (es) * 2004-12-06 2007-08-06 Avigen Inc Ibudilast para tratar dolor neuropatico y sindromes asociados.
GB0507695D0 (en) 2005-04-15 2005-05-25 Novartis Ag Organic compounds
PT1928438E (pt) 2005-09-26 2013-04-03 Avigen Inc Método para tratamento de dependências de drogas e comportamentos
US7985756B2 (en) * 2005-10-21 2011-07-26 Braincells Inc. Modulation of neurogenesis by PDE inhibition
WO2007142924A1 (en) 2006-05-31 2007-12-13 Avigen, Inc. Ibudilast for inhibiting macrophage migration inhibitory factor (mif) activity
CA2669463A1 (en) 2006-11-09 2008-05-15 Avigen, Inc. Method for treating delirium
EP2131841B1 (en) 2007-01-30 2012-08-01 Avigen, Inc. Methods for treating acute pain

Also Published As

Publication number Publication date
US20070072899A1 (en) 2007-03-29
JP2009509975A (ja) 2009-03-12
JP5411504B2 (ja) 2014-02-12
PT1928438E (pt) 2013-04-03
EP1928438A2 (en) 2008-06-11
BRPI0616344A2 (pt) 2011-06-14
WO2007038551A2 (en) 2007-04-05
CA2623072A1 (en) 2007-04-05
RU2008116720A (ru) 2009-11-10
EP1928438B1 (en) 2013-03-20
ES2412858T3 (es) 2013-07-12
PL1928438T3 (pl) 2013-08-30
US7915285B2 (en) 2011-03-29
WO2007038551A3 (en) 2007-06-28
HK1120737A1 (en) 2009-04-09
AU2006294758A1 (en) 2007-04-05

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