DK1931735T3 - Texaphyrinmetalkomplekser med høj renhed - Google Patents

Texaphyrinmetalkomplekser med høj renhed

Info

Publication number
DK1931735T3
DK1931735T3 DK05807302.4T DK05807302T DK1931735T3 DK 1931735 T3 DK1931735 T3 DK 1931735T3 DK 05807302 T DK05807302 T DK 05807302T DK 1931735 T3 DK1931735 T3 DK 1931735T3
Authority
DK
Denmark
Prior art keywords
metal complexes
texaphyrin metal
compositions
high purity
purity
Prior art date
Application number
DK05807302.4T
Other languages
English (en)
Inventor
Hugo Madden
Greg Hemmi
Tarak Mody
Original Assignee
Pharmacyclics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacyclics Inc filed Critical Pharmacyclics Inc
Application granted granted Critical
Publication of DK1931735T3 publication Critical patent/DK1931735T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0076—PDT with expanded (metallo)porphyrins, i.e. having more than 20 ring atoms, e.g. texaphyrins, sapphyrins, hexaphyrins, pentaphyrins, porphocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/36—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C205/37—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B47/00—Porphines; Azaporphines
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B69/00—Dyes not provided for by a single group of this subclass

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK05807302.4T 2005-09-26 2005-09-26 Texaphyrinmetalkomplekser med høj renhed DK1931735T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2005/034684 WO2007040506A1 (en) 2005-09-26 2005-09-26 High-purity texaphyrin metal complexes

Publications (1)

Publication Number Publication Date
DK1931735T3 true DK1931735T3 (da) 2012-01-30

Family

ID=37906444

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05807302.4T DK1931735T3 (da) 2005-09-26 2005-09-26 Texaphyrinmetalkomplekser med høj renhed

Country Status (9)

Country Link
EP (1) EP1931735B1 (da)
JP (1) JP2009509954A (da)
CN (1) CN101309976B (da)
AT (1) ATE531766T1 (da)
CA (1) CA2623334C (da)
DK (1) DK1931735T3 (da)
ES (1) ES2376581T3 (da)
PL (1) PL1931735T3 (da)
WO (1) WO2007040506A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5685232B2 (ja) * 2012-09-07 2015-03-18 ファーマサイクリクス,インコーポレイテッド 高純度テキサフィリン金属錯体

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5457183A (en) * 1989-03-06 1995-10-10 Board Of Regents, The University Of Texas System Hydroxylated texaphyrins
US5886173A (en) * 1997-07-30 1999-03-23 Pharmacyclics, Inc. Metallation of macrocycles with 2,4-dicarbonyl-metal complexes
PT1104431E (pt) * 1998-08-11 2003-03-31 Ciba Sc Holding Ag Metalocenil-ftalocianinas
AU1233701A (en) * 1999-10-29 2001-05-14 Board Of Regents, The University Of Texas System Methods and compositions for treating atheroma, tumors and other neoplastic tissue
WO2002017910A1 (en) * 2000-08-30 2002-03-07 Pharmacyclics, Inc. Agents for neutron capture therapy
AU2003298725A1 (en) * 2002-12-04 2004-06-23 Pharmacyclics, Inc. Preparation of metallotexaphyrins

Also Published As

Publication number Publication date
PL1931735T3 (pl) 2012-03-30
EP1931735A4 (en) 2010-07-14
JP2009509954A (ja) 2009-03-12
EP1931735A1 (en) 2008-06-18
ES2376581T3 (es) 2012-03-15
HK1120065A1 (en) 2009-03-20
ATE531766T1 (de) 2011-11-15
EP1931735B1 (en) 2011-11-02
CN101309976A (zh) 2008-11-19
CN101309976B (zh) 2012-12-12
WO2007040506A1 (en) 2007-04-12
CA2623334A1 (en) 2007-04-12
CA2623334C (en) 2013-11-12

Similar Documents

Publication Publication Date Title
TW200510416A (en) P38 inhibitors and methods of use thereof
DE602004022316D1 (de) Legierungszusammensetzungen und diese enthaltende vorrichtungen
MX2011006959A (es) Compuestos substituidos de 5,6-dihidro-6-fenilbenzo [f] isoquinolina-2-amina.
PL1951729T3 (pl) Pochodne pirymidyny połączone przez atom tlenu
MX2009000285A (es) Piperidinas sustituidas que incrementan la actividad de p53 y usos de las mismas.
GEP20125565B (en) Lactam compounds and their pharmaceutical use
EA201001143A1 (ru) Активаторы прокаспаз "исполнителей" 3, 6 и 7
MY149957A (en) Heterocyclic inhibitors of mek and methods of use thereof
MY140840A (en) Acylated, heteroaryl-condensed cycloalkenylamines and their use as pharmaceuticals
UA101493C2 (ru) Производные азетидина и циклобутана как ингибиторы jak
GEP20104994B (en) Tetrahydroindolone and tetrahydroindazolone derivatives
ATE477251T1 (de) Pyrrolverbindungen als glykogen synthase kinase 3 inhibitoren
IL184898A0 (en) Pyrrolopyrimidine derivatives and pharmaceutical compositions containing the same
TW200510367A (en) Novel lapachone compounds, their preparation, and the use thereof
MXPA05012894A (es) Benzofuranos 3-sustituidos como agentes terapeuticos.
WO2007076085A3 (en) Fused pyrimidones and thiopyrimidones, and uses thereof
UA86400C2 (ru) Применение эритропоэтина в низком дозировании для пациентов с дисфункцией эндотелиальных клеток-предшественников, сердечно-сосудистым фактором риска и повреждением конечного органа
IL171974A0 (en) Tetrahydrocarbazole derivatives and their pharmaceutical use
TW200716091A (en) New therapeutic combinations for the treatment or prevention of psychotic disorders
MX2008001982A (es) Compuestos nitro-o, sus composiciones farmaceuticas y sus usos.
MXPA05003718A (es) Compuestos x-nitro, sus composiciones farmaceuticas y sus usos.
WO2007076087A3 (en) 3-aryl-substituted quinazolones, and uses thereof
EP1507778A4 (en) POLZYCLIC CARBOXYLAMIDE AMIDE WITH ANTITUMORIC EFFECT
MY150098A (en) Benzylpiperazine derivates and their medical use
GB0407025D0 (en) Novel compounds