DK195087A - Heterocyclisk og alkansulfonamidophenyl-substituerede aminer og deres anvendelse til fremstilling af antiarrytmiske laegemidler samt farmaceutiske praeparater indeholdende disse forbindelser - Google Patents
Heterocyclisk og alkansulfonamidophenyl-substituerede aminer og deres anvendelse til fremstilling af antiarrytmiske laegemidler samt farmaceutiske praeparater indeholdende disse forbindelserInfo
- Publication number
- DK195087A DK195087A DK195087A DK195087A DK195087A DK 195087 A DK195087 A DK 195087A DK 195087 A DK195087 A DK 195087A DK 195087 A DK195087 A DK 195087A DK 195087 A DK195087 A DK 195087A
- Authority
- DK
- Denmark
- Prior art keywords
- rarithmic
- alkansulphonamidophenyl
- medicines
- heterocyclic
- compounds
- Prior art date
Links
- 150000001412 amines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Indole Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868609331A GB8609331D0 (en) | 1986-04-16 | 1986-04-16 | Anti-arrythmia agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK195087D0 DK195087D0 (da) | 1987-04-15 |
| DK195087A true DK195087A (da) | 1987-10-17 |
Family
ID=10596325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK195087A DK195087A (da) | 1986-04-16 | 1987-04-15 | Heterocyclisk og alkansulfonamidophenyl-substituerede aminer og deres anvendelse til fremstilling af antiarrytmiske laegemidler samt farmaceutiske praeparater indeholdende disse forbindelser |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US4863948A (da) |
| EP (1) | EP0242173A1 (da) |
| JP (1) | JPS62255474A (da) |
| KR (1) | KR870010012A (da) |
| AU (1) | AU575745B2 (da) |
| CA (1) | CA1295616C (da) |
| DK (1) | DK195087A (da) |
| FI (1) | FI871635A7 (da) |
| GB (1) | GB8609331D0 (da) |
| HU (1) | HU198014B (da) |
| IL (1) | IL82205A (da) |
| NZ (1) | NZ219990A (da) |
| PT (1) | PT84675B (da) |
| ZA (1) | ZA872703B (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8609331D0 (en) * | 1986-04-16 | 1986-05-21 | Pfizer Ltd | Anti-arrythmia agents |
| US4956382A (en) * | 1987-02-07 | 1990-09-11 | Pfizer Inc. | Sulfonamide anti-arrhythmic agents |
| US5262413A (en) * | 1989-06-26 | 1993-11-16 | Sankyo Company, Limited | Use of isoxazolin-3-one derivatives as antidepressants |
| US5217970A (en) * | 1989-06-26 | 1993-06-08 | Sankyo Company, Limited | Use of isoxazolin-3-one derivatives as antidepressants |
| US5215989A (en) * | 1989-12-08 | 1993-06-01 | Merck & Co., Inc. | Nitrogen-containing heterocyclic compounds as class III antiarrhythmic agents |
| US5112824A (en) * | 1989-12-08 | 1992-05-12 | Merck & Co., Inc. | Benzofuran compounds as class III antiarrhythmic agents |
| US5032598A (en) * | 1989-12-08 | 1991-07-16 | Merck & Co., Inc. | Nitrogens containing heterocyclic compounds as class III antiarrhythmic agents |
| US5032604A (en) * | 1989-12-08 | 1991-07-16 | Merck & Co., Inc. | Class III antiarrhythmic agents |
| JP2807577B2 (ja) * | 1990-06-15 | 1998-10-08 | エーザイ株式会社 | 環状アミド誘導体 |
| GB9021056D0 (en) * | 1990-09-27 | 1990-11-07 | Pfizer Ltd | Antiarrhythmic agents |
| FR2674524B1 (fr) * | 1991-03-25 | 1993-05-21 | Adir | Nouveaux amides alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| US5198443A (en) * | 1991-06-28 | 1993-03-30 | Warner-Lambert Company | Substituted 1,2,3,6-tetrahydropyridines as central nervous system agents |
| KR960007566A (ko) * | 1994-08-19 | 1996-03-22 | 김정규 | 신규한 퀴놀릴아민 유도체, 그의 제조방법 및 항부정맥제로서의 용도 |
| US5741798A (en) * | 1996-06-03 | 1998-04-21 | Boehringer Ingelheim Pharmaceuticals, Inc. | 2-benzyl-4-sulfonyl-4H-isoquinolin-1,3-diones and their use as antiinflammatory agents |
| GB9711220D0 (en) * | 1997-05-30 | 1997-07-23 | Isis Innovation | Antiarrhythmic agents |
| CA2488699A1 (en) * | 2002-06-12 | 2003-12-24 | Sumitomo Pharmaceuticals Co., Ltd. | Indole, indazole, and benzazole derivative |
| PL383550A1 (pl) * | 2007-10-15 | 2009-04-27 | Uniwersytet Łódzki | Nowe pochodne benzeno- i pirydopirydazynonów |
| US9745308B2 (en) * | 2014-09-12 | 2017-08-29 | Chiesi Farmaceutici S.P.A. | Pyridazinone derivatives as phoshoinositide 3-kinases inhibitors |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB993584A (da) * | 1962-01-24 | |||
| FR4290M (da) * | 1964-06-05 | 1966-07-18 | ||
| US3478149A (en) * | 1962-01-24 | 1969-11-11 | Mead Johnson & Co | Therapeutic compositions and methods employing sulfonamidophenethanolamines |
| LU47776A1 (da) * | 1964-07-30 | 1966-07-13 | ||
| US3758692A (en) * | 1969-04-14 | 1973-09-11 | Mead Johnson & Co | Ylamines sympathomimetic process and compositions employing sulfonamidophenalk |
| US3574741A (en) * | 1969-04-14 | 1971-04-13 | Mead Johnson & Co | Sulfonamidophenalkylamines |
| GB1263987A (en) * | 1969-05-30 | 1972-02-16 | Allen & Hanburys Ltd | Phenethylamine derivatives |
| US3623623A (en) * | 1969-09-05 | 1971-11-30 | Reflex Corp Canada Ltd | Childproof safety package |
| BE757005A (fr) * | 1969-10-02 | 1971-04-02 | Bristol Myers Co | Phenethanolamines substituees et procede pour leur preparation |
| DD123741A5 (da) * | 1975-03-06 | 1977-01-12 | ||
| US4087541A (en) * | 1975-03-06 | 1978-05-02 | Boehringer Ingelheim Gmbh | 2-(Aralkylaminoalkyl)phthalimidines |
| DE2609645A1 (de) * | 1976-03-09 | 1977-09-15 | Boehringer Sohn Ingelheim | Aminoalkylheterocyclen |
| DE2639291A1 (de) * | 1976-09-01 | 1978-03-02 | Thomae Gmbh Dr K | Neue aryl-alkylamine |
| DE2639718C2 (de) * | 1976-09-03 | 1987-03-05 | Dr. Karl Thomae Gmbh, 7950 Biberach | 1-[6,7-Dimethoxy-3,4-dihydro-2H-isochinolin-1-on-2-yl]-3-[N-methyl-N-(2-(3,4-dimethoxy-phenyl)-äthyl)-amino]-propan, dessen physiologisch verträgliche Säureadditionssalze und diese Verbindungen enthaltende Arzneimittel |
| CH645628A5 (en) * | 1977-01-01 | 1984-10-15 | Thomae Gmbh Dr K | Phenylethylamines |
| DE2833140A1 (de) * | 1978-07-28 | 1980-02-07 | Boehringer Sohn Ingelheim | Neue n-substituierte heterocyclen |
| FR2533563A1 (fr) * | 1982-09-23 | 1984-03-30 | Adir | Nouveaux derives de la sulfonyluree, leurs procedes de preparation et les compositions pharmaceutiques les renfermant |
| US4460581A (en) * | 1982-10-12 | 1984-07-17 | Boehringer Ingelheim Kg | (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones |
| FR2541999B1 (fr) * | 1983-03-04 | 1986-09-19 | Bristol Myers Co | Phenethanolamines et leurs utilisations |
| US4581370A (en) * | 1983-07-12 | 1986-04-08 | Schering A.G. | Antiarrhythmic imidazoliums |
| DE3566886D1 (en) * | 1984-05-04 | 1989-01-26 | Upjohn Co | N-(aminoalkylphenyl)sulfonamides their preparation and therapeutic use |
| JPS61124941A (ja) * | 1984-11-21 | 1986-06-12 | Fuji Photo Film Co Ltd | 加熱工程を有する画像形成方法 |
| GB8609331D0 (en) * | 1986-04-16 | 1986-05-21 | Pfizer Ltd | Anti-arrythmia agents |
| DE3623944A1 (de) * | 1986-07-16 | 1988-02-11 | Thomae Gmbh Dr K | Neue benzolsulfonamido-indanylverbindungen, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
-
1986
- 1986-04-16 GB GB868609331A patent/GB8609331D0/en active Pending
-
1987
- 1987-04-09 US US07/037,309 patent/US4863948A/en not_active Expired - Lifetime
- 1987-04-13 IL IL82205A patent/IL82205A/xx unknown
- 1987-04-13 AU AU71442/87A patent/AU575745B2/en not_active Ceased
- 1987-04-14 PT PT84675A patent/PT84675B/pt not_active IP Right Cessation
- 1987-04-14 EP EP87303236A patent/EP0242173A1/en not_active Ceased
- 1987-04-14 FI FI871635A patent/FI871635A7/fi not_active IP Right Cessation
- 1987-04-14 CA CA000534603A patent/CA1295616C/en not_active Expired - Lifetime
- 1987-04-15 ZA ZA872703A patent/ZA872703B/xx unknown
- 1987-04-15 HU HU871675A patent/HU198014B/hu not_active IP Right Cessation
- 1987-04-15 NZ NZ219990A patent/NZ219990A/xx unknown
- 1987-04-15 KR KR870003594A patent/KR870010012A/ko not_active Ceased
- 1987-04-15 DK DK195087A patent/DK195087A/da not_active Application Discontinuation
- 1987-04-16 JP JP62094253A patent/JPS62255474A/ja active Pending
-
1989
- 1989-06-02 US US07/360,517 patent/US4990509A/en not_active Expired - Lifetime
-
1990
- 1990-11-21 US US07/617,112 patent/US5114952A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FI871635A0 (fi) | 1987-04-14 |
| IL82205A (en) | 1991-05-12 |
| HU198014B (en) | 1989-07-28 |
| US4990509A (en) | 1991-02-05 |
| DK195087D0 (da) | 1987-04-15 |
| CA1295616C (en) | 1992-02-11 |
| FI871635A7 (fi) | 1987-10-17 |
| AU7144287A (en) | 1987-12-10 |
| ZA872703B (en) | 1989-07-26 |
| JPS62255474A (ja) | 1987-11-07 |
| HUT44528A (en) | 1988-03-28 |
| PT84675A (en) | 1987-05-01 |
| AU575745B2 (en) | 1988-08-04 |
| US4863948A (en) | 1989-09-05 |
| KR870010012A (ko) | 1987-11-30 |
| IL82205A0 (en) | 1987-10-30 |
| EP0242173A1 (en) | 1987-10-21 |
| US5114952A (en) | 1992-05-19 |
| NZ219990A (en) | 1989-08-29 |
| GB8609331D0 (en) | 1986-05-21 |
| PT84675B (pt) | 1989-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |