DK197786A - N-substituerede 2-aminothiazoler, fremgangsmaade til deres fremstilling og praeparater, der indeholder dem - Google Patents

N-substituerede 2-aminothiazoler, fremgangsmaade til deres fremstilling og praeparater, der indeholder dem Download PDF

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Publication number
DK197786A
DK197786A DK197786A DK197786A DK197786A DK 197786 A DK197786 A DK 197786A DK 197786 A DK197786 A DK 197786A DK 197786 A DK197786 A DK 197786A DK 197786 A DK197786 A DK 197786A
Authority
DK
Denmark
Prior art keywords
alkyl
group
aminothiazoles
substituted
hydrogen atom
Prior art date
Application number
DK197786A
Other languages
English (en)
Other versions
DK197786D0 (da
DK168523B1 (da
Inventor
Claude Coquelet
Daniel Sincholle
Claude Bonne
Alain Alazet
Original Assignee
Chauvin Blache Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chauvin Blache Lab filed Critical Chauvin Blache Lab
Publication of DK197786D0 publication Critical patent/DK197786D0/da
Publication of DK197786A publication Critical patent/DK197786A/da
Application granted granted Critical
Publication of DK168523B1 publication Critical patent/DK168523B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Description

Forbindelserne har anti-inflammatorisk og anti-allergisk virkning og kan anvendes inden for terapien, især inden for det okulare område.
DK197786A 1985-04-30 1986-04-30 N-substituerede 2-aminothiazoler, fremgangsmåde til deres fremstilling og præparater, der indeholder dem DK168523B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8506568 1985-04-30
FR8506568A FR2581063B1 (fr) 1985-04-30 1985-04-30 Amino-2 thiazoles n-substitues, leur procede de preparation et leur application en therapeutique

Publications (3)

Publication Number Publication Date
DK197786D0 DK197786D0 (da) 1986-04-30
DK197786A true DK197786A (da) 1986-10-31
DK168523B1 DK168523B1 (da) 1994-04-11

Family

ID=9318828

Family Applications (1)

Application Number Title Priority Date Filing Date
DK197786A DK168523B1 (da) 1985-04-30 1986-04-30 N-substituerede 2-aminothiazoler, fremgangsmåde til deres fremstilling og præparater, der indeholder dem

Country Status (11)

Country Link
US (1) US4785008A (da)
EP (1) EP0202157B1 (da)
JP (1) JPH0629270B2 (da)
AT (1) ATE45734T1 (da)
CA (1) CA1289144C (da)
DE (1) DE3665176D1 (da)
DK (1) DK168523B1 (da)
ES (1) ES8900045A1 (da)
FR (1) FR2581063B1 (da)
IE (1) IE59141B1 (da)
PT (1) PT82480B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868183A (en) * 1986-07-21 1989-09-19 Otsuka Pharmaceutical Factory, Inc. N-pyrazinyl substituted P-aminophenols
JPS6339868A (ja) * 1986-08-04 1988-02-20 Otsuka Pharmaceut Factory Inc ジ低級アルキルフエノ−ル誘導体
FR2612187B1 (fr) * 1987-03-12 1989-07-21 Sanofi Sa Derives du thiazole actifs sur le systeme cholinergique, leur procede de preparation et compositions pharmaceutiques en contenant
WO1990009985A1 (en) * 1989-02-23 1990-09-07 Otsuka Pharmaceutical Factory, Inc. p-AMINOPHENOL DERIVATIVE AND PRODUCTION AND APPLICATION THEREOF
JPH03111178U (da) * 1990-02-27 1991-11-14
US6090846A (en) * 1994-06-01 2000-07-18 Glaxo Wellcome Inc. Substituted urea and isothiourea derivatives as no synthase inhibitors
US6225305B1 (en) 1993-10-04 2001-05-01 Glaxo Wellcome Inc. Substituted urea and isothiorea derivatives as no synthase inhibitors
US6297276B1 (en) 1993-10-04 2001-10-02 Glaxosmithkline Substituted urea and isothiourea derivatives as no synthase inhibitors
EP0723438A1 (en) * 1993-10-04 1996-07-31 The Wellcome Foundation Limited Substituted urea and isothiourea derivatives as no synthase inhibitors
GB9418912D0 (en) * 1994-09-20 1994-11-09 Fisons Corp Pharmaceutically active compounds
US6100282A (en) 1998-01-02 2000-08-08 Hoffman-La Roche Inc. Thiazole derivatives
DE60035271D1 (en) 1999-04-28 2007-08-02 Inst Med Molecular Design Inc Pyrimidincarbonsäurederivate
IL148385A0 (en) * 1999-09-10 2002-09-12 Merck & Co Inc Tyrosine kinase inhibitors
US20080221088A1 (en) * 2005-06-23 2008-09-11 Vijay Kumar Potluri 3,4-Substituted Thiazoles as Ampk Activators
JP2009500351A (ja) * 2005-07-04 2009-01-08 ドクター レディズ ラボラトリーズ リミテッド Ａｍｐｋアクチベータとしてのチアゾール誘導体
JP5571062B2 (ja) * 2008-03-19 2014-08-13 バイエル・クロップサイエンス・アーゲー 殺真菌剤ヒドロキシモイル−テトラゾール誘導体
US10696638B2 (en) 2017-12-26 2020-06-30 Industrial Technology Research Institute Compounds for inhibiting AGC kinase and pharmaceutical compositions comprising the same
KR20210015892A (ko) 2018-05-29 2021-02-10 세르시 테라퓨틱스 인코포레이티드 통증 치료를 위한 화합물, 이를 포함하는 조성물 및 이를 사용하는 방법
MX2021013524A (es) 2019-05-10 2021-12-10 Cersci Therapeutics Inc Metodos de fabricacion y polimorfos de un agente antihiperalgesico de tiazolina.
CN118546107A (zh) * 2024-05-15 2024-08-27 中国药科大学 一类2-噻唑氨基苯酚衍生物及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE603739A (da) * 1960-05-13
US3299087A (en) 1961-04-24 1967-01-17 Geigy Chem Corp Nu, nu'-bis-(thiazolyl)-phenylenediamines
US3467666A (en) * 1966-11-07 1969-09-16 Geigy Chem Corp 2-substituted aminothiazoles
BE795907A (fr) * 1972-02-25 1973-06-18 Luso Farmaco Inst 2-amino-4-arylthiazoles 5-substitues et leur preparation
JPS5742629B2 (da) * 1973-10-29 1982-09-09
JPS565747B2 (da) * 1973-10-24 1981-02-06
JPS5833870B2 (ja) * 1976-01-12 1983-07-22 塩野義製薬株式会社 チアゾリン誘導体
DK150068C (da) * 1978-06-02 1987-06-29 Pfizer Analogifremgangsmaade til fremstilling af aminothiazoler

Also Published As

Publication number Publication date
PT82480B (pt) 1988-03-03
PT82480A (en) 1986-05-01
EP0202157A1 (fr) 1986-11-20
FR2581063A1 (fr) 1986-10-31
US4785008A (en) 1988-11-15
DK197786D0 (da) 1986-04-30
ES554503A0 (es) 1988-11-16
CA1289144C (en) 1991-09-17
DE3665176D1 (en) 1989-09-28
ES8900045A1 (es) 1988-11-16
DK168523B1 (da) 1994-04-11
JPS6277375A (ja) 1987-04-09
IE59141B1 (en) 1994-01-12
ATE45734T1 (de) 1989-09-15
FR2581063B1 (fr) 1987-07-17
JPH0629270B2 (ja) 1994-04-20
EP0202157B1 (fr) 1989-08-23
IE861119L (en) 1986-10-30

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed