DK197787D0 - Synergistisk kombination af amantadin og selegilin - Google Patents

Synergistisk kombination af amantadin og selegilin

Info

Publication number: DK197787D0
Authority: DK; Denmark
Prior art keywords: amantadine; selegilin; synergistic combination; combination; synergistic
Prior art date: 1986-04-16

Application number

DK197787A

Other languages

English (en)

Other versions

DK197787A (da

DK168514B1 (da

Inventor

Dirk Reischig

Helmut Hettche

Wolfgang Brade

Original Assignee

Degussa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-04-16

Filing date

1987-04-15

Publication date

1987-04-15

1987-04-15 Application filed by Degussa filed Critical Degussa

1987-04-15 Publication of DK197787D0 publication Critical patent/DK197787D0/da

1987-10-17 Publication of DK197787A publication Critical patent/DK197787A/da

1994-04-11 Application granted granted Critical

1994-04-11 Publication of DK168514B1 publication Critical patent/DK168514B1/da

Links

DKNWSYNQZKUICI-UHFFFAOYSA-N amantadine Chemical compound C1C(C2)CC3CC2CC1(N)C3 DKNWSYNQZKUICI-UHFFFAOYSA-N 0.000 title abstract 2
229960003805 amantadine Drugs 0.000 title abstract 2
239000011885 synergistic combination Substances 0.000 title 1
239000003814 drug Substances 0.000 abstract 1
MEZLKOACVSPNER-GFCCVEGCSA-N selegiline Chemical compound C#CCN(C)[C@H](C)CC1=CC=CC=C1 MEZLKOACVSPNER-GFCCVEGCSA-N 0.000 abstract 1
229960003946 selegiline Drugs 0.000 abstract 1
230000002195 synergetic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/315—Zinc compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Neurology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)
Luminescent Compositions (AREA)
Saccharide Compounds (AREA)
Medicinal Preparation (AREA)

DK197787A 1986-04-16 1987-04-15 Synergistisk produkt indeholdende en kombination af amantadin og selegilin, fremgangsmåde til fremstilling af produktet og anvendelse af amantadin og selegilin til fremstilling af produktet DK168514B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3612702		1986-04-16
DE3612702		1986-04-16

Publications (3)

Publication Number	Publication Date
DK197787D0 true DK197787D0 (da)	1987-04-15
DK197787A DK197787A (da)	1987-10-17
DK168514B1 DK168514B1 (da)	1994-04-11

Family

ID=6298731

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK197787A DK168514B1 (da)	1986-04-16	1987-04-15	Synergistisk produkt indeholdende en kombination af amantadin og selegilin, fremgangsmåde til fremstilling af produktet og anvendelse af amantadin og selegilin til fremstilling af produktet

Country Status (19)

Country	Link
US (1)	US4812481A (da)
EP (1)	EP0241809B1 (da)
JP (1)	JPS62249923A (da)
AT (1)	ATE55245T1 (da)
AU (1)	AU598533B2 (da)
CA (1)	CA1298200C (da)
DD (1)	DD259352A5 (da)
DE (1)	DE3764144D1 (da)
DK (1)	DK168514B1 (da)
ES (1)	ES2029805T3 (da)
FI (1)	FI871668L (da)
GR (1)	GR3000707T3 (da)
HU (1)	HU197840B (da)
IE (1)	IE60245B1 (da)
IL (1)	IL82216A0 (da)
NO (1)	NO871581L (da)
PL (1)	PL265152A1 (da)
PT (1)	PT84684B (da)
ZA (1)	ZA872690B (da)

Families Citing this family (41)

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US6150328A (en)	1986-07-01	2000-11-21	Genetics Institute, Inc.	BMP products
US4861800A (en) *	1987-08-18	1989-08-29	Buyske Donald A	Method for administering the drug deprenyl so as to minimize the danger of side effects
GB8807504D0 (en) *	1988-03-29	1988-05-05	Sandoz Ltd	Improvements in/relating to organic compounds
HU208484B (en) *	1988-08-17	1993-11-29	Chinoin Gyogyszer Es Vegyeszet	Process for producing pharmaceutical composition containing acid additional salt of selegilin as active component for treating schisofrenia
EP0536277A1 (en) *	1990-06-25	1993-04-14	The Du Pont Merck Pharmaceutical Company	Amantadine hydrochloride suspension with enhanced dissolution characteristics for use in soft gelatin capsules
US5175002A (en) *	1991-10-02	1992-12-29	Du Pont Merck Pharmaceutical Company	Amantadine hydrochloride syspension with enhanced dissolution characteristics for use in soft gelatin capsules
DE69233022T2 (de)	1991-11-04	2004-02-12	Genetics Institute, LLC, Cambridge	Rekombinante knochenmorphogenetische protein heterodimere, zusammensetzungen und verfahren zur verwendung
HUT63579A (en) *	1991-12-20	1993-09-28	Chinoin Gyogyszer Es Vegyeszet	Process for producing double-phase pharmaceutical compositions suitable for treating diseases occurring during neurodegenerative processes
US5817336A (en) *	1993-04-02	1998-10-06	Orion-Yhtyma Oy	Composition containing selegiline
US6291206B1 (en)	1993-09-17	2001-09-18	Genetics Institute, Inc.	BMP receptor proteins
DE69434651T2 (de)	1993-12-07	2007-03-08	Genetics Institute, Inc., Cambridge	Bmp-12, bmp-13 und diese enthaltende sehne-induzierende zusammensetzungen
US5484608A (en) *	1994-03-28	1996-01-16	Pharmavene, Inc.	Sustained-release drug delivery system
GB9426079D0 (en) *	1994-12-23	1995-02-22	Orion Yhtymae Oy	A gelatine capsule
US6348208B1 (en)	1995-01-13	2002-02-19	Somerset Pharmaceuticals, Inc.	Methods and pharmaceutical compositions employing desmethylselegiline
US6299901B1 (en)	1995-01-13	2001-10-09	Somerset Pharmaceuticals, Inc.	Methods and pharmaceutical compositions employing desmethylselegiline
US6319954B1 (en)	1995-01-13	2001-11-20	Somerset Pharmaceuticals, Inc.	S-(+)-desmethylselegiline and its use in the therapeutic methods and pharmaceutical compositions
US6033682A (en) *	1995-01-13	2000-03-07	Somerset Pharmaceuticals, Inc.	S(+) desmethylselegiline and its use in therapeutic methods and pharmaceutical compositions
DE19533772C1 (de) *	1995-09-12	1998-01-02	Hexal Ag	Tacrin/Selegilin-Pflaster
CA2236368C (en) *	1995-11-06	2001-10-23	Somerset Pharmaceuticals, Inc.	Sublingual and buccal administration of selegiline
DE19716905C1 (de) *	1997-04-22	1998-08-27	Iip Inst Fuer Ind Pharmazie Fo	Stabile, wäßrige Lösung auf der Grundlage von Selegilin und Vorrichtung zu ihrer Verabreichung
GB9715082D0 (en) *	1997-07-17	1997-09-24	Scherer Ltd R P	Treatment of attention deficit hyperactivity disorder and narcolepsy
BR9908713A (pt)	1998-03-16	2000-11-21	Somerset Pharmaceuticals Inc	Uso de selegilina ou desmetil-selegilina para tratamento de feridas, queimaduras e danos dermatológicos
US6727224B1 (en)	1999-02-01	2004-04-27	Genetics Institute, Llc.	Methods and compositions for healing and repair of articular cartilage
WO2001034172A2 (en) *	1999-11-05	2001-05-17	Vela Pharmaceuticals Inc.	Methods and compositions for treating reward deficiency syndrome
US20040122090A1 (en) *	2001-12-07	2004-06-24	Lipton Stuart A.	Methods for treating neuropsychiatric disorders with nmda receptor antagonists
WO2002099037A2 (en)	2001-06-01	2002-12-12	Wyeth	Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
TWI267378B (en)	2001-06-08	2006-12-01	Wyeth Corp	Calcium phosphate delivery vehicles for osteoinductive proteins
WO2003075906A1 (en) *	2002-03-04	2003-09-18	Somerset Pharmaceuticals, Inc.	Methods for preventing and treating peripheral neuropathy by administering desmethylselegiline
EP1622450A4 (en) *	2003-04-25	2009-11-18	Endo Pharmaceuticals Solutions	PROCESS FOR PROMOTING UNINTERRUPTED SLEEP BY ADMINISTERING TROPIUM CHLORIDE
DE10338174A1 (de) *	2003-08-20	2005-03-24	Lts Lohmann Therapie-Systeme Ag	Transdermale Arzneimittelzubereitungen mit Wirkstoffkombinationen zur Behandlung der Parkinson-Krankheit
DE602004005477T2 (de)	2003-09-12	2007-12-13	Wyeth	Injizierbare feste Calciumphosphat-Stäbe zur Abgabe von osteogenen Proteinen
WO2005072705A1 (en) *	2004-01-29	2005-08-11	Neuromolecular, Inc.	Combination of a nmda receptor antagonist and a mao-inhibitor or a gadpf-inhibitor for the treatment of central nervous system-related conditions
EP1734920A2 (en) *	2004-02-13	2006-12-27	Neuromolecular Inc.	Combination of a nmda receptor antagonist and an mao-inhibitor or a gadph-inhibitor for the treatment of psychiatric conditions
US7619007B2 (en) *	2004-11-23	2009-11-17	Adamas Pharmaceuticals, Inc.	Method and composition for administering an NMDA receptor antagonist to a subject
CA2588296A1 (en)	2004-11-24	2006-06-01	Neuromolecular Pharmaceuticals, Inc.	Composition comprising an nmda receptor antagonist and levodopa and use thereof for treating neurological disease
WO2006091544A2 (en) *	2005-02-22	2006-08-31	Northwestern University	Methods and compositions for modulating calcium channels
EP2201963B1 (en)	2005-04-05	2016-01-27	Yale University	Glutamate modulating agents in the treatment of mental disorders
JP5666087B2 (ja)	2005-04-06	2015-02-12	アダマス・ファーマシューティカルズ・インコーポレーテッド	Ｃｎｓ関連疾患の治療のための方法及び組成物
MX2010013393A (es) †	2008-06-06	2011-06-21	Pharma Two B Ltd	Composiciones farmaceuticas para el tratamiento de la enfermedad de parkinson.
AU2010325960C1 (en)	2009-12-02	2015-08-06	Adamas Pharma, Llc	Amantadine compositions and methods of use
US10154971B2 (en)	2013-06-17	2018-12-18	Adamas Pharma, Llc	Methods of administering amantadine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE314077C (da) *
AT314077B (de) *	1972-01-07	1974-03-25	Hurka Wilhelm	Verfahren zur Herstellung eines neuen, gegen den Parkinsonismus wirksamen Kombinationspräparates
HU193662B (en) *	1983-12-20	1987-11-30	Chinoin Gyogyszer Es Vegyeszet	Process for producing synergetic pharmaceutical composition of antidepressive aktivity

1987
- 1987-04-01 AT AT87104818T patent/ATE55245T1/de not_active IP Right Cessation
- 1987-04-01 EP EP87104818A patent/EP0241809B1/de not_active Expired - Lifetime
- 1987-04-01 ES ES198787104818T patent/ES2029805T3/es not_active Expired - Lifetime
- 1987-04-01 DE DE8787104818T patent/DE3764144D1/de not_active Expired - Lifetime
- 1987-04-13 JP JP62088986A patent/JPS62249923A/ja active Pending
- 1987-04-14 DD DD87301815A patent/DD259352A5/de unknown
- 1987-04-14 NO NO871581A patent/NO871581L/no unknown
- 1987-04-14 PL PL1987265152A patent/PL265152A1/xx unknown
- 1987-04-14 ZA ZA872690A patent/ZA872690B/xx unknown
- 1987-04-14 IE IE97387A patent/IE60245B1/en not_active IP Right Cessation
- 1987-04-15 CA CA000534793A patent/CA1298200C/en not_active Expired - Lifetime
- 1987-04-15 AU AU71541/87A patent/AU598533B2/en not_active Ceased
- 1987-04-15 US US07/038,566 patent/US4812481A/en not_active Expired - Fee Related
- 1987-04-15 DK DK197787A patent/DK168514B1/da not_active IP Right Cessation
- 1987-04-15 PT PT84684A patent/PT84684B/pt not_active IP Right Cessation
- 1987-04-15 FI FI871668A patent/FI871668L/fi not_active Application Discontinuation
- 1987-04-16 HU HU871687A patent/HU197840B/hu not_active IP Right Cessation
- 1987-04-16 IL IL82216A patent/IL82216A0/xx unknown
1990
- 1990-08-09 GR GR90400531T patent/GR3000707T3/el unknown

Also Published As

Publication number	Publication date
ES2029805T3 (es)	1992-10-01
ATE55245T1 (de)	1990-08-15
DK197787A (da)	1987-10-17
FI871668A7 (fi)	1987-10-17
IE870973L (en)	1987-10-16
AU598533B2 (en)	1990-06-28
DD259352A5 (de)	1988-08-24
IE60245B1 (en)	1994-06-15
US4812481A (en)	1989-03-14
AU7154187A (en)	1987-10-29
NO871581D0 (no)	1987-04-14
PT84684B (pt)	1989-12-29
PT84684A (de)	1987-05-01
HUT43789A (en)	1987-12-28
PL265152A1 (en)	1988-07-07
EP0241809A1 (de)	1987-10-21
ZA872690B (en)	1988-03-30
FI871668L (fi)	1987-10-17
EP0241809B1 (de)	1990-08-08
IL82216A0 (en)	1987-10-30
CA1298200C (en)	1992-03-31
NO871581L (no)	1987-10-19
JPS62249923A (ja)	1987-10-30
DK168514B1 (da)	1994-04-11
DE3764144D1 (de)	1990-09-13
HU197840B (en)	1989-06-28
GR3000707T3 (en)	1991-10-10
FI871668A0 (fi)	1987-04-15

Legal Events

Date	Code	Title	Description
1994-04-11	B1	Patent granted (law 1993)
1997-12-22	PBP	Patent lapsed

Publication	Publication Date	Title
DK197787A (da)	1987-10-17	Synergistisk kombination af amantadin og selegilin
DE3789518D1 (de)	1994-05-11	Verbundfolie und antistatische Verbundfolie.
NO873905D0 (no)	1987-09-17	Elastisk stoff.
DK30486A (da)	1986-07-24	Synergitisk kombination af flupirtin og ikke-ste-roide antiflogistika
DK160541C (da)	1991-09-09	Barbermaskinehoved
NO893800D0 (no)	1989-09-25	Herdbare polycykloolefinharpiksopploesninger og deres anvendelse.
DK150784D0 (da)	1984-02-29	Lege-og instruktionsorgan
NO902949L (no)	1990-07-02	Fiberoptisk kanisteradhesiv og anvendelse derav.
DK413187A (da)	1988-02-09	Semicarbazoner og thiosemicarbazoner
FI892848A0 (fi)	1989-06-09	Lektin och foerfarande foer dess extraktion ur en kammussla.
TR24875A (tr)	1992-07-07	Fungusidlerde veya bunlarla ilgili islahat
IT210635Z2 (it)	1988-12-30	Calendario in special modo agenda tascabile o da tavolo
DK36387D0 (da)	1987-01-22	Desinficerende og steriliserende praeparat
NO862473D0 (no)	1986-06-20	Plastdel og anvendelse derav.
DK296490A (da)	1991-02-15	Praeserveringsmiddel og anvendelse heraf
ES1000520Y (es)	1989-10-01	Estuche escolar perfeccionado
ES294391Y (es)	1987-08-16	Estuche escolar perfeccionado
NO880860L (no)	1988-02-26	Immunomodulerende blandinger og anvendelse derav.
DK408486D0 (da)	1986-08-27	Roersamleorgan og anvendelse heraf
DK408586D0 (da)	1986-08-27	Roersamleorgan og anvendelse heraf
IT8435596V0 (it)	1984-02-21	Vedo e doso
BR6600656U (pt)	1988-01-12	Lousa escolar desmontavel e portatil
RO93626A2 (ro)	1988-02-29	Material de amprentare termoplastic utilizat in stomatologie
IT8786218A0 (it)	1987-10-27	Nel mio nome
BR8606343A (pt)	1987-04-28	Mesa de seno simples e dupla