DK1984008T3 - Krystal af ACE-N- domæne - Google Patents
Krystal af ACE-N- domæneInfo
- Publication number
- DK1984008T3 DK1984008T3 DK07700357.2T DK07700357T DK1984008T3 DK 1984008 T3 DK1984008 T3 DK 1984008T3 DK 07700357 T DK07700357 T DK 07700357T DK 1984008 T3 DK1984008 T3 DK 1984008T3
- Authority
- DK
- Denmark
- Prior art keywords
- ace
- domain
- crystal
- Prior art date
Links
- 239000013078 crystal Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/485—Exopeptidases (3.4.11-3.4.19)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4813—Exopeptidases (3.4.11. to 3.4.19)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/15—Peptidyl-dipeptidases (3.4.15)
- C12Y304/15001—Peptidyl-dipeptidase A (3.4.15.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0600406.3A GB0600406D0 (en) | 2006-01-10 | 2006-01-10 | Crystal |
| PCT/GB2007/000064 WO2007080400A2 (en) | 2006-01-10 | 2007-01-10 | Ace n-domain crystal |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1984008T3 true DK1984008T3 (da) | 2012-10-01 |
Family
ID=35911628
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07700357.2T DK1984008T3 (da) | 2006-01-10 | 2007-01-10 | Krystal af ACE-N- domæne |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US8796006B2 (da) |
| EP (1) | EP1984008B1 (da) |
| AU (1) | AU2007204226B2 (da) |
| CA (1) | CA2636633C (da) |
| DK (1) | DK1984008T3 (da) |
| GB (1) | GB0600406D0 (da) |
| WO (1) | WO2007080400A2 (da) |
| ZA (1) | ZA200806312B (da) |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3947575A (en) | 1969-06-30 | 1976-03-30 | E. R. Squibb & Sons, Inc. | Peptides as argiotensin converting enzyme inhibitors |
| US3832337A (en) | 1970-07-28 | 1974-08-27 | Squibb & Sons Inc | Peptide enzyme inhibitors |
| US3891616A (en) | 1974-04-17 | 1975-06-24 | Squibb & Sons Inc | Hypotensive {62 -homoaminoacid nonapeptides |
| US4052511A (en) | 1976-02-13 | 1977-10-04 | E. R. Squibb & Sons, Inc. | Carboxyacylproline derivatives |
| US4053651A (en) | 1976-05-10 | 1977-10-11 | E. R. Squibb & Sons, Inc. | Compounds and method for alleviating angiotensin related hypertension |
| JPS59501572A (ja) | 1982-05-19 | 1984-09-06 | ユニリーバー ナームローゼ ベンノートシヤープ | クルイベロミセス属酵母およびその製造法 |
| DE3480411D1 (en) | 1983-07-06 | 1989-12-14 | Gist Brocades Nv | Molecular cloning and expression in industrial microorganism species |
| US4885249A (en) | 1984-12-05 | 1989-12-05 | Allelix, Inc. | Aspergillus niger transformation system |
| ATE253119T1 (de) | 1985-04-15 | 2003-11-15 | Dsm Ip Assets Bv | Verwendung des glucoamylasepromotors aus apergillus |
| NO872932L (no) | 1986-07-18 | 1988-01-19 | Gist Brocades Nv | Fremgangsmaate for fremstilling av proteiner med faktorviiiaktivitet ved hjelp av mikrobielle vertsceller, eksprimeringsvektorer, vertsceller, antibiotika. |
| AR247761A1 (es) | 1987-07-28 | 1995-03-31 | Gist Brocades Nv | Metodo para producir un polipeptido en una celula hospedante de kluyveromyces, dicha celula hospedante transformada y secuencia a adn empleada |
| FR2649412B1 (fr) | 1989-07-05 | 1995-10-20 | Inst Nat Sante Rech Med | Acide nucleique codant pour l'enzyme de conversion de l'angiotensine (eca) testiculaire humaine, et ses applications, notamment pour le depistage in vitro de cette enzyme dans l'organisme |
| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| JPH03251543A (ja) | 1990-02-26 | 1991-11-11 | Unitika Ltd | アンジオテンシン変換酵素阻害剤 |
| GB9711643D0 (en) | 1997-06-05 | 1997-07-30 | Janssen Pharmaceutica Nv | Glass thermoplastic systems |
| US20040033532A1 (en) | 2002-08-08 | 2004-02-19 | Ehlers Mario R. W. | Use of three-dimensional crystal structure coordinates to design and synthesize domain-selective inhibitors for angiotensin-converting enzyme (ACE) |
| GB0221169D0 (en) | 2002-09-12 | 2002-10-23 | Univ Bath | Crystal |
-
2006
- 2006-01-10 GB GBGB0600406.3A patent/GB0600406D0/en not_active Ceased
-
2007
- 2007-01-10 EP EP07700357A patent/EP1984008B1/en active Active
- 2007-01-10 AU AU2007204226A patent/AU2007204226B2/en not_active Ceased
- 2007-01-10 CA CA2636633A patent/CA2636633C/en active Active
- 2007-01-10 WO PCT/GB2007/000064 patent/WO2007080400A2/en not_active Ceased
- 2007-01-10 US US12/160,562 patent/US8796006B2/en active Active
- 2007-01-10 ZA ZA200806312A patent/ZA200806312B/xx unknown
- 2007-01-10 DK DK07700357.2T patent/DK1984008T3/da active
-
2014
- 2014-06-05 US US14/297,500 patent/US9434933B2/en active Active
-
2016
- 2016-08-04 US US15/228,108 patent/US9670473B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP1984008B1 (en) | 2012-06-13 |
| EP1984008A2 (en) | 2008-10-29 |
| AU2007204226B2 (en) | 2012-08-02 |
| US9434933B2 (en) | 2016-09-06 |
| ZA200806312B (en) | 2009-12-30 |
| CA2636633C (en) | 2019-02-05 |
| US9670473B2 (en) | 2017-06-06 |
| US20100173977A1 (en) | 2010-07-08 |
| US8796006B2 (en) | 2014-08-05 |
| US20140377836A1 (en) | 2014-12-25 |
| WO2007080400A3 (en) | 2007-11-08 |
| CA2636633A1 (en) | 2007-07-19 |
| AU2007204226A1 (en) | 2007-07-19 |
| US20160333334A1 (en) | 2016-11-17 |
| WO2007080400A2 (en) | 2007-07-19 |
| GB0600406D0 (en) | 2006-02-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE528296T1 (de) | Polymorphe form von 4-ä3-(4- cyclopropancarbonylpiperazin-1-carbonyl)-4- fluorbenzylü-2h-phthalazin-1-on | |
| DK2099973T3 (da) | Udfoldning af gabion | |
| DK2024504T4 (da) | Fremstilling af isoprenoider | |
| DK2111555T3 (da) | Diagnosticering af præeklampsi | |
| DK2318396T5 (da) | Krystalform af posaconazol | |
| NO20091286L (no) | Krystallfabrikasjon | |
| HRP20170222T1 (hr) | Kristalni oblik karbamoil-cikloheksan derivata | |
| DK2219469T3 (da) | Modificering af enzymatisk disponerede proteiner | |
| DK1981859T3 (da) | Fremstilling af delmopinol | |
| DE602007002135D1 (de) | Kristalloszillator | |
| DK2086944T3 (da) | Fremgangsmåde til fremstilling af difluormethylpyrazolylcarboxylater | |
| DK2041270T3 (da) | Fremstilling af glycoproteiner | |
| DK1989008T3 (da) | Fremstilling af sekundære aggregater | |
| DK3225251T3 (da) | Modulering af pro-neurotrofinaktivitet | |
| DOP2007000084A (es) | Derivados de dihidropirazolopirimidinona | |
| DK2700786T3 (da) | Modifikation af overførselspassage | |
| DK2094676T3 (da) | Ny fremgangsmåde til fremstillingen af 2-iminothiazolidin-4-on-derivater | |
| DK1979314T3 (da) | Indolsulfonamidmodulatorer af progesteronreceptorer | |
| DK2262793T3 (da) | Krystallinske former af nilotinib-hci | |
| CR10562A (es) | Nuevos derivados de piridazina | |
| DK1981875T3 (da) | Substituerede indolylalkylaminoderivater som inhibitorer af histondeacetylase | |
| DK2091945T3 (da) | Nye inhibitorer af glutaminylcyclase | |
| DK2153565T3 (da) | Valg af transmissionsmodus | |
| DK2358714T3 (da) | Alkylcyclohexylethere af dihydrotetraazabenzoazulener | |
| DK2083629T3 (da) | Krystallinsk modifikation af fipronil |