DK199786A - Radiofarmaceutisk forbindelse til diagnostisk anvendelse, fremgangsmaade og udstyr til anvendelse deraf - Google Patents

Radiofarmaceutisk forbindelse til diagnostisk anvendelse, fremgangsmaade og udstyr til anvendelse deraf Download PDF

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Publication number
DK199786A
DK199786A DK199786A DK199786A DK199786A DK 199786 A DK199786 A DK 199786A DK 199786 A DK199786 A DK 199786A DK 199786 A DK199786 A DK 199786A DK 199786 A DK199786 A DK 199786A
Authority
DK
Denmark
Prior art keywords
radiopharmaceutical
procedure
relationship
equipment
diagnostic
Prior art date
Application number
DK199786A
Other languages
English (en)
Other versions
DK199786D0 (da
Inventor
Hank Fan-Iuan Kung
Simon Mbua Ngale Efange
Chi-Chou Yu
Monte Blau
Original Assignee
Univ New York State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York State Res Found filed Critical Univ New York State Res Found
Publication of DK199786D0 publication Critical patent/DK199786D0/da
Publication of DK199786A publication Critical patent/DK199786A/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

at tillade passage af forbindelserne fra et pattedyrs blod ind i et målorgan eller målvæv og en tilstrækkelig lav lipofilicitet ved et pH på 6,6 til at forhindre hurtig tilbagevenden af forbindelserne fra målorganet eller målvævet til blodet. Der omhandles også en fremgangsmåde og et .udstyr til selektiv deponering af en radiofarmaceutisk forbindelse i mindst ét målvæv eller ét målorgan i et pattedyr, hvilket væv eller organ har en pH-værdi, der væsentligt afviger fra værdien for pattedyrets blod, ved hvilken man indfører en eller flere' forbindelser ifølge opfindelsen i pattedyrets blodstrem.
DK199786A 1985-05-01 1986-05-01 Radiofarmaceutisk forbindelse til diagnostisk anvendelse, fremgangsmaade og udstyr til anvendelse deraf DK199786A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72930085A 1985-05-01 1985-05-01
US72930085 1985-05-01

Publications (2)

Publication Number Publication Date
DK199786D0 DK199786D0 (da) 1986-05-01
DK199786A true DK199786A (da) 1986-11-02

Family

ID=24930418

Family Applications (1)

Application Number Title Priority Date Filing Date
DK199786A DK199786A (da) 1985-05-01 1986-05-01 Radiofarmaceutisk forbindelse til diagnostisk anvendelse, fremgangsmaade og udstyr til anvendelse deraf

Country Status (6)

Country Link
EP (1) EP0200211A1 (da)
JP (1) JPS6296460A (da)
AU (1) AU5702786A (da)
DK (1) DK199786A (da)
GR (1) GR861158B (da)
ZA (1) ZA863205B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3728599A1 (de) * 1986-12-10 1988-06-23 Hoechst Ag Verfahren zur herstellung einer mit technetium-99m-markierten organspezifischen substanz
US5279811A (en) * 1987-02-18 1994-01-18 The Du Pont Merck Pharmaceutical Company Ester-substituted diaminedithiols and radiolabeled complexes thereof
US5071636A (en) * 1987-12-29 1991-12-10 Nihon Medi-Physics Co., Ltd. Chelating compounds and their use
DE69006698T2 (de) * 1989-12-12 1994-05-26 Amersham Int Plc Phenyldiaminodithiolderivate.
US5656253A (en) * 1990-09-14 1997-08-12 Mallinckrodt Medical, Inc. Ligands useful in radiographic imaging
AU8721591A (en) * 1990-09-14 1992-04-15 Mallinckrodt Medical, Inc. Novel nitrogen-sulfur ligands useful in radiographic imaging agents
US5908931A (en) * 1990-12-14 1999-06-01 Mallinckrodt Inc. Preorganized hexadentate ligands useful in radiographic imaging agents
US5997844A (en) * 1991-02-08 1999-12-07 Diatide, Inc. Technetium-99m labeled peptides for imaging
US7238340B1 (en) 1991-11-27 2007-07-03 Cis Bio International Monoamine, diamide, thiol-containing metal chelating agents
US5965107A (en) * 1992-03-13 1999-10-12 Diatide, Inc. Technetium-99m labeled peptides for imaging
DE4405140A1 (de) * 1994-02-18 1995-08-24 Hoechst Ag Komplexbildner für in der Nuklearmedizin einsetzbare Nuklide, Verfahren zur Herstellung der Komplexe, sowie Diagnostikum enthaltend diese Komplexe
CA2190727C (en) * 1994-05-19 2006-07-18 Sudhakar Kasina Aromatic amine substituted bridged nitrogen and sulfur donor atom ligands for imaging
WO1995032192A1 (en) * 1994-05-19 1995-11-30 Neorx Corporation Aromatic amine substituted bridged nitrogen and sulfur donor atom ligands for imaging
US6005083A (en) 1997-03-28 1999-12-21 Neorx Corporation Bridged aromatic substituted amine ligands with donor atoms
US6515131B2 (en) 2000-02-22 2003-02-04 Biostream Therapeutics, Inc. Imagining agents for diagnosis of Parkinson's disease
CA2407592C (en) * 2000-04-28 2011-03-22 President And Fellows Of Harvard College Small technetium-99m and rhenium labeled agents and methods for imaging tumors
FR2981073B1 (fr) * 2011-10-07 2013-12-27 Pharmamens Composes piegeurs d'alpha-oxoaldehydes et d'aldehydes alpha, beta-insatures, compositions les contenant et leurs utilisations dans des traitements de maladies liees a l'accumulation des age et ale.
RU2565778C1 (ru) * 2014-04-24 2015-10-20 Федеральное Государственное Бюджетное Учреждение Науки Институт Нефтехимии И Катализа Ран Способ получения 1,7-дитиа-3,5-диазациклоалкан-4-онов

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4434151A (en) * 1982-11-08 1984-02-28 Medi-Physics, Inc. Bifunctional chelating agents
US4673562A (en) * 1983-08-19 1987-06-16 The Children's Medical Center Corporation Bisamide bisthiol compounds useful for making technetium radiodiagnostic renal agents
US4638051A (en) * 1984-04-30 1987-01-20 The Johns Hopkins University Brain imaging radiopharmaceuticals

Also Published As

Publication number Publication date
EP0200211A1 (en) 1986-11-05
AU5702786A (en) 1986-11-06
GR861158B (en) 1986-08-26
DK199786D0 (da) 1986-05-01
ZA863205B (en) 1987-08-26
JPS6296460A (ja) 1987-05-02

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