DK200100444A - Farmaceutisk formulering samt anvendelse heraf til fremstilling af et middel til behandling af kredsløbssygdomme. - Google Patents
Farmaceutisk formulering samt anvendelse heraf til fremstilling af et middel til behandling af kredsløbssygdomme. Download PDFInfo
- Publication number
- DK200100444A DK200100444A DK200100444A DKPA200100444A DK200100444A DK 200100444 A DK200100444 A DK 200100444A DK 200100444 A DK200100444 A DK 200100444A DK PA200100444 A DKPA200100444 A DK PA200100444A DK 200100444 A DK200100444 A DK 200100444A
- Authority
- DK
- Denmark
- Prior art keywords
- pharmaceutical formulation
- treatment
- preparation
- agent
- well
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract description 3
- 238000009472 formulation Methods 0.000 abstract description 14
- 239000000203 mixture Substances 0.000 abstract description 14
- YKPUWZUDDOIDPM-SOFGYWHQSA-N capsaicin Chemical compound COC1=CC(CNC(=O)CCCC\C=C\C(C)C)=CC=C1O YKPUWZUDDOIDPM-SOFGYWHQSA-N 0.000 abstract description 8
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 abstract description 8
- 235000017663 capsaicin Nutrition 0.000 abstract description 4
- 229960002504 capsaicin Drugs 0.000 abstract description 4
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract description 4
- 235000012754 curcumin Nutrition 0.000 abstract description 4
- 229940109262 curcumin Drugs 0.000 abstract description 4
- 239000004148 curcumin Substances 0.000 abstract description 4
- VFLDPWHFBUODDF-UHFFFAOYSA-N diferuloylmethane Natural products C1=C(O)C(OC)=CC(C=CC(=O)CC(=O)C=CC=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-UHFFFAOYSA-N 0.000 abstract description 4
- 235000012000 cholesterol Nutrition 0.000 abstract description 2
- 241001071795 Gentiana Species 0.000 abstract 1
- 230000002425 cardiocirculatory effect Effects 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 235000012141 vanillin Nutrition 0.000 description 3
- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 3
- FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 description 3
- 240000004160 Capsicum annuum Species 0.000 description 1
- 235000008534 Capsicum annuum var annuum Nutrition 0.000 description 1
- 235000007862 Capsicum baccatum Nutrition 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 244000163122 Curcuma domestica Species 0.000 description 1
- 235000003392 Curcuma domestica Nutrition 0.000 description 1
- 244000290333 Vanilla fragrans Species 0.000 description 1
- 235000009499 Vanilla fragrans Nutrition 0.000 description 1
- 235000012036 Vanilla tahitensis Nutrition 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 239000001728 capsicum frutescens Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 235000003373 curcuma longa Nutrition 0.000 description 1
- 239000007884 disintegrant Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000013976 turmeric Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/51—Gentianaceae (Gentian family)
- A61K36/515—Gentiana
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Alternative & Traditional Medicine (AREA)
- Cardiology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Description
PATENTKRAV 1. Farmaceutisk formulering, kendetegnet ved, at den som aktive bestanddele omfatter capsaicin, curcumin og ensian. 2. Formulering ifølge krav 1,kendetegnet ved, at den omfatter en daglig dosis på 0,2 - 2,0 mg capsaicin. 3. Formulering ifølge krav 2, kendetegnet ved, at den omfatter en daglig dosis på 0,5 - 1,5 mg capsaicin. 4. Formulering ifølge krav 1,kendetegnet ved, at den omfatter en daglig dosis på 5 - 20 mg curcumin. 5. Formulering ifølge krav 4, kendetegnet ved, at den omfatter en daglig dosis på 7 - 15 mg curcumin. 6. Formulering ifølge krav 1,kendetegnet ved, at den omfatter en daglig dosis på 100 - 500 mg ensianrod. 7. Formulering ifølge krav 6, kendetegnet ved, at den omfatter en daglig dosis på 200 - 400 mg ensianrod. 8. Formulering ifølge krav 1,kendetegnet ved, at den endvidere omfatter vanillin. 9. Formulering ifølge krav 8, kendetegnet ved, at den omfatter en daglig dosis på 0,2 - 1,5 mg vanillin. 10. Formulering ifølge krav 9, kendetegnet ved, at den omfatter en daglig dosis på 0,3 - 1,3 mg vanillin. 11. Formulering ifølge krav 8, kendetegnet ved, at den omfatter en daglig dosis på 75-125 mg formalet spansk rød peber 15-25 mg vanilje 250-350 mg formalet ensianrod 450-550 mg formalet gurkemejerod. 12. Formulering ifølge ethvert af de foregående krav, kendetegnet ved, at den endvidere omfatter et eller flere konventionelle hjælpestoffer valgt blandt fyldstoffer, smøremidler, bindemidler, desintegreringsmidler, farvestoffer og aromastoffer. 13. Anvendelse af en formulering ifølge ethvert af kravene 1-12 til fremstilling af et middel til behandling af hjertekredsløbssygdomme. 14. Anvendelse af en formulering ifølge ethvert af kravene 1-13 til fremstilling af et middel til behandling af kolesterolubalance.
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK200100444A DK174072B1 (da) | 2001-03-15 | 2001-03-15 | Farmaceutisk formulering samt anvendelse heraf til fremstilling af et middel til behandling af kredsløbssygdomme. |
| PCT/DK2002/000177 WO2002074319A1 (en) | 2001-03-15 | 2002-03-15 | Pharmaceutical formulation and the use thereof for preparing a medicament for the treatment of cardiovascular diseases |
| ES02704637T ES2236487T3 (es) | 2001-03-15 | 2002-03-15 | Formulacion farmaceutica y su uso para preparar un medicamento para el tratamiento de enfermedades cardiovasculares. |
| DE60202446T DE60202446T8 (de) | 2001-03-15 | 2002-03-15 | Pharmazeutische formulierung und ihre verwendung für die herstellung eines medikaments zur behandlung von herz-kreislauf-erkrankungen |
| EP02704637A EP1368046B1 (en) | 2001-03-15 | 2002-03-15 | Pharmaceutical formulation and the use thereof for preparing a medicament for the treatment of cardiovascular diseases |
| AT02704637T ATE285784T1 (de) | 2001-03-15 | 2002-03-15 | Pharmazeutische formulierung und ihre verwendung für die herstellung eines medikaments zur behandlung von herz-kreislauf-erkrankungen |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK200100444 | 2001-03-15 | ||
| DK200100444A DK174072B1 (da) | 2001-03-15 | 2001-03-15 | Farmaceutisk formulering samt anvendelse heraf til fremstilling af et middel til behandling af kredsløbssygdomme. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK174072B1 DK174072B1 (da) | 2002-05-21 |
| DK200100444A true DK200100444A (da) | 2002-05-21 |
Family
ID=8160371
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK200100444A DK174072B1 (da) | 2001-03-15 | 2001-03-15 | Farmaceutisk formulering samt anvendelse heraf til fremstilling af et middel til behandling af kredsløbssygdomme. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1368046B1 (da) |
| AT (1) | ATE285784T1 (da) |
| DE (1) | DE60202446T8 (da) |
| DK (1) | DK174072B1 (da) |
| ES (1) | ES2236487T3 (da) |
| WO (1) | WO2002074319A1 (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX339101B (es) | 2011-03-11 | 2016-05-11 | Jose Arturo Castañeda Miranda | Polifarmaco herbario para la prevencion y el tratamiento de la ateroesclerosis. |
| US9907786B2 (en) | 2014-10-21 | 2018-03-06 | Ions Pharmaceutical S.À R.L. | Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof |
| US10092550B2 (en) | 2014-10-21 | 2018-10-09 | Ions Pharmaceutical S.À R.L. | Therapeutic compositions containing curcumin, harmine, and isovanillin components, and methods of use thereof |
| US20160106687A1 (en) | 2014-10-21 | 2016-04-21 | Life Plus, LLC | Human therapeutic agents |
| CN107496849A (zh) * | 2017-10-11 | 2017-12-22 | 湖南中医药大学 | 一种治疗冠心病的药物及其制备方法 |
| US12129265B2 (en) | 2020-07-21 | 2024-10-29 | Ankh Life Sciences Limited | Therapeutic agents and uses thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0739350B2 (ja) * | 1990-08-03 | 1995-05-01 | ゼリア新薬工業株式会社 | 生薬配合チュアブル錠 |
| US6440464B1 (en) * | 1996-06-10 | 2002-08-27 | Viva Life Science | Nutritive composition for cardiovascular health containing fish oil, garlic, rutin, capsaicin, selenium, vitamins and juice concentrates |
| CN1209281A (zh) * | 1998-07-30 | 1999-03-03 | 李树春 | 月苋草花茶 |
-
2001
- 2001-03-15 DK DK200100444A patent/DK174072B1/da not_active IP Right Cessation
-
2002
- 2002-03-15 ES ES02704637T patent/ES2236487T3/es not_active Expired - Lifetime
- 2002-03-15 AT AT02704637T patent/ATE285784T1/de not_active IP Right Cessation
- 2002-03-15 EP EP02704637A patent/EP1368046B1/en not_active Expired - Lifetime
- 2002-03-15 DE DE60202446T patent/DE60202446T8/de not_active Expired - Fee Related
- 2002-03-15 WO PCT/DK2002/000177 patent/WO2002074319A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ATE285784T1 (de) | 2005-01-15 |
| DK174072B1 (da) | 2002-05-21 |
| EP1368046A1 (en) | 2003-12-10 |
| EP1368046B1 (en) | 2004-12-29 |
| ES2236487T3 (es) | 2005-07-16 |
| DE60202446D1 (de) | 2005-02-03 |
| WO2002074319A1 (en) | 2002-09-26 |
| DE60202446T2 (de) | 2006-01-12 |
| DE60202446T8 (de) | 2006-08-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |
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