DK200289A - Anvendelse af et 4-quinolincarboxylsyrederivat eller et farmaceutisk egnet salt deraf til fremstilling af et immunosuppresivt virksomt farmaceutisk praeparat - Google Patents

Anvendelse af et 4-quinolincarboxylsyrederivat eller et farmaceutisk egnet salt deraf til fremstilling af et immunosuppresivt virksomt farmaceutisk praeparat Download PDF

Info

Publication number: DK200289A
Authority: DK; Denmark
Prior art keywords: preparation; pharmaceutical; acid derivative; suitable salt; immunosuppressive effective
Prior art date: 1988-04-26

Application number

DK200289A

Other languages

English (en)

Other versions

DK200289D0 (da

DK170414B1 (da

Inventor

Neil Richard Ackerman

Bruce Donald Jaffee

Scott Edward Loveless

Russell Howard Neubauer

Original Assignee

Du Pont

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-04-26

Filing date

1989-04-25

Publication date

1989-10-27

1989-04-25 Application filed by Du Pont filed Critical Du Pont

1989-04-25 Publication of DK200289D0 publication Critical patent/DK200289D0/da

1989-10-27 Publication of DK200289A publication Critical patent/DK200289A/da

1995-08-28 Application granted granted Critical

1995-08-28 Publication of DK170414B1 publication Critical patent/DK170414B1/da

Links

VQMSRUREDGBWKT-UHFFFAOYSA-N quinoline-4-carboxylic acid Chemical class C1=CC=C2C(C(=O)O)=CC=NC2=C1 VQMSRUREDGBWKT-UHFFFAOYSA-N 0.000 title abstract 2
230000001506 immunosuppresive effect Effects 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
150000003839 salts Chemical class 0.000 title 1
208000023275 Autoimmune disease Diseases 0.000 abstract 1
229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
239000002260 anti-inflammatory agent Substances 0.000 abstract 1
208000037976 chronic inflammation Diseases 0.000 abstract 1
208000037893 chronic inflammatory disorder Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
208000024908 graft versus host disease Diseases 0.000 abstract 1
230000002519 immonomodulatory effect Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
238000002054 transplantation Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Transplantation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

DK200289A 1988-04-26 1989-04-25 Anvendelse af et 4-quinolincarboxylsyrederivat eller et farmaceutisk egnet salt deraf til fremstilling af farmaceutiske præparater DK170414B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/186,243 US4968701A (en)	1988-04-26	1988-04-26	4-Quinoline carboxylic acid derivatives useful as immunosuppressive agents
US18624388		1988-04-26

Publications (3)

Publication Number	Publication Date
DK200289D0 DK200289D0 (da)	1989-04-25
DK200289A true DK200289A (da)	1989-10-27
DK170414B1 DK170414B1 (da)	1995-08-28

Family

ID=22684181

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK200289A DK170414B1 (da)	1988-04-26	1989-04-25	Anvendelse af et 4-quinolincarboxylsyrederivat eller et farmaceutisk egnet salt deraf til fremstilling af farmaceutiske præparater

Country Status (13)

Country	Link
US (1)	US4968701A (da)
EP (1)	EP0339485B1 (da)
JP (1)	JP2650757B2 (da)
KR (1)	KR0134376B1 (da)
AT (1)	ATE87480T1 (da)
CA (1)	CA1333155C (da)
DE (1)	DE68905642T2 (da)
DK (1)	DK170414B1 (da)
IE (1)	IE64760B1 (da)
IL (1)	IL90055A (da)
MY (1)	MY106038A (da)
PT (1)	PT90363B (da)
ZA (1)	ZA893087B (da)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE202005021811U1 (de)	2004-09-27	2010-04-15	Novozymes A/S	Körnchen mit einem Kern und einer Beschichtung

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5102883A (en) *	1989-10-31	1992-04-07	Du Pont Merck Pharmaceutical Company	Pyrimidine biosynthesis inhibitors useful as immunosuppressive agents
US5204329A (en) *	1990-06-11	1993-04-20	Du Pont Merck Pharmaceutical Company	Treatment of organ transplantation rejection
US5135934A (en) *	1990-07-06	1992-08-04	Du Pont Merck Pharmaceutical Company	3-phenyl-5,6-dihydrobenz(c) acridine-7-carboxylic acids and related compounds as immunosuppressive agents
US6004979A (en) *	1991-02-07	1999-12-21	Hoechst Marion Roussel	Nitrogenous bicycles
MX9200299A (es) *	1991-02-07	1992-12-01	Roussel Uclaf	Nuevos derivados biciclicos nitrogenados, su procedimiento de preparacion los nuevos compuestos intermedios obtenidos su aplicacion como medicamentos y las composiciones farmaceuticas que los contienen.
US6077823A (en) *	1991-03-11	2000-06-20	Creative Biomolecules, Inc.	Method for reducing tissue damage associated with ischemia-reperfusion or hypoxia injury
US6194376B1 (en)	1991-03-11	2001-02-27	Creative Biomolecules, Inc.	Method for modulating inflammatory response comprising administering morphogen
TW232013B (da) *	1992-04-24	1994-10-11	Takeda Pharm Industry Co Ltd
US5409886A (en) *	1993-02-18	1995-04-25	Mitsui Toatsu Chemicals, Incorporated	3-pyrroline-2-one derivatives and herbicidal compositions containing same
US5428040A (en) *	1993-08-31	1995-06-27	The Du Pont Merck Pharmaceutical Company	Carbocyclic fused-ring quinolinecarboxylic acids useful as immunosuppressive agents
US5578609A (en) *	1994-03-25	1996-11-26	The Dupont Merck Pharmaceutical Company	2-carbocyclic and 2-heterocyclic quinoline-4-carboxylic acids and salts thereof useful as immunosuppressive agents
AU715358B2 (en) *	1995-04-28	2000-01-20	Takeda Chemical Industries Ltd.	Therapeutic composition for arthritis
AU2896097A (en) *	1996-05-10	1997-12-05	Novartis Ag	Use of brequinar and derivatives in chronic rejection of allografts and xenotransplantation
DK0825186T3 (da) *	1996-08-16	2002-07-22	Pfizer	2-aminobenzazepinderivater og deres anvendelse til behandling af immunosuppression
US6103905A (en) *	1997-06-19	2000-08-15	Sepracor, Inc.	Quinoline-indole antimicrobial agents, uses and compositions related thereto
US6207679B1 (en)	1997-06-19	2001-03-27	Sepracor, Inc.	Antimicrobial agents uses and compositions related thereto
US6376670B1 (en)	1997-06-19	2002-04-23	Sepracor Inc.	Quinoline-indole antimicrobial agents, uses and compositions related thereto
WO1998057931A2 (en)	1997-06-19	1998-12-23	Sepracor Inc.	Quinoline-indole antimicrobial agents, uses and compositions related thereto
AU2108099A (en) *	1998-01-30	1999-08-16	Procept, Inc.	Immunosuppressive agents
EP3071199A2 (en)	2013-11-22	2016-09-28	Genzyme Corporation	Novel methods for treating neurodegenerative diseases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR6592M (da) *	1967-10-31	1968-12-30
GB1334705A (en) *	1970-06-19	1973-10-24	Ici Ltd	Pharmaceutical compositions containing kynurenic acid derivatives
CH567477A5 (da) *	1972-03-10	1975-10-15	Ciba Geigy Ag
US4407803A (en) *	1981-08-17	1983-10-04	Abbott Laboratories	Antiinflammatory 1-(quinolinyl)-2-pyrazoline derivatives
US4680299A (en) *	1984-04-30	1987-07-14	E.I. Du Pont De Nemours And Company	2-phenyl-4-quinolinecarboxylic acids and pharmaceutical compositions thereof
US4625034A (en) *	1985-02-04	1986-11-25	Usv Pharmaceutical Corp.	1,2-Dihydro; 1,2,3,4-tetrahydro; 5,8 dihydro; and 5,6,7,8-tetrahydroquinoline derivatives
US4847381A (en) *	1987-08-31	1989-07-11	American Cyanamid Company	2-Phenyl-4-quinoline carboxylic acids

1988
- 1988-04-26 US US07/186,243 patent/US4968701A/en not_active Expired - Fee Related
1989
- 1989-04-20 EP EP89107099A patent/EP0339485B1/en not_active Expired - Lifetime
- 1989-04-20 AT AT89107099T patent/ATE87480T1/de active
- 1989-04-20 DE DE8989107099T patent/DE68905642T2/de not_active Expired - Fee Related
- 1989-04-24 KR KR1019890005349A patent/KR0134376B1/ko not_active Expired - Fee Related
- 1989-04-24 PT PT90363A patent/PT90363B/pt not_active IP Right Cessation
- 1989-04-24 IL IL90055A patent/IL90055A/xx not_active IP Right Cessation
- 1989-04-25 DK DK200289A patent/DK170414B1/da not_active IP Right Cessation
- 1989-04-25 JP JP1103586A patent/JP2650757B2/ja not_active Expired - Lifetime
- 1989-04-25 IE IE132889A patent/IE64760B1/en not_active IP Right Cessation
- 1989-04-26 ZA ZA893087A patent/ZA893087B/xx unknown
- 1989-04-26 MY MYPI89000544A patent/MY106038A/en unknown
- 1989-04-26 CA CA000597842A patent/CA1333155C/en not_active Expired - Fee Related

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE202005021811U1 (de)	2004-09-27	2010-04-15	Novozymes A/S	Körnchen mit einem Kern und einer Beschichtung
DE202005021810U1 (de)	2004-09-27	2010-04-22	Novozymes A/S	Körnchen mit einem Kern und einer Beschichtung

Also Published As

Publication number	Publication date
DK200289D0 (da)	1989-04-25
US4968701A (en)	1990-11-06
DK170414B1 (da)	1995-08-28
JP2650757B2 (ja)	1997-09-03
ATE87480T1 (de)	1993-04-15
ZA893087B (en)	1990-12-28
EP0339485A1 (en)	1989-11-02
AU628045B2 (en)	1992-09-10
PT90363B (pt)	1994-08-31
IL90055A0 (en)	1989-12-15
CA1333155C (en)	1994-11-22
DE68905642D1 (de)	1993-05-06
JPH01313428A (ja)	1989-12-18
DE68905642T2 (de)	1993-08-12
KR900016137A (ko)	1990-11-12
PT90363A (pt)	1989-11-10
IE891328L (en)	1989-10-26
IL90055A (en)	1993-05-13
KR0134376B1 (ko)	1998-04-21
EP0339485B1 (en)	1993-03-31
IE64760B1 (en)	1995-09-06
AU3332189A (en)	1989-11-02
MY106038A (en)	1994-03-31

Similar Documents

Publication	Publication Date	Title
DK200289A (da)	1989-10-27	Anvendelse af et 4-quinolincarboxylsyrederivat eller et farmaceutisk egnet salt deraf til fremstilling af et immunosuppresivt virksomt farmaceutisk praeparat
DK653688A (da)	1989-05-25	Stabiliserede laegemiddelaktive forbindelser, fremgangsmaade til deres frmstilling samt stabile laegemiddelpraeparater
NO883073L (no)	1989-01-11	3-desmetyl-mevalonsyrederivater, fremgangsmaate for fremstilling av dem, farmasoeytiske preparater paa basis av disse forbindelsene, deres anvendelse saavel som mellomprodukter.
PT87474A (pt)	1989-05-31	Process for the preparation of pharmaceutical compounds which contain ester 1-acetoxi-ethylic of cefuroxime
DK39082A (da)	1982-08-03	Aromatiske heterocycliske estre af steroider,fremgangsmaade til deres fremstilling samt deres anvendelse
EP0936217A4 (en)	2000-01-05	1-PHENYLPYROZOL COMPOUNDS AND THEIR MEDICAL APPLICATION
ATE50255T1 (de)	1990-02-15	Substituierte 9-fluor-3-methyl-7-oxo-2,3-dihydro7h-pyrido(1,2,3-de>(1,4>benzoxazin-6-carbonsaeur ; substituierte 5-amino-6-fluor-1,4-dihydro-4-oxochinolin-3-carbons\|ure; substituierte 5-amino-6fluor-1,4-dihydro-4-oxo-1,8-naphthyridin-3- carbonsaeure; ihre derivate; diese enthaltende pharmazeutische zubereitungen und verfahren
SE7903186L (sv)	1979-10-12	Cerebralverksamt medel
NO883506D0 (no)	1988-08-05	Fremgangsmaate for fremstilling av foretrede polyoksyalkylenderivater.
DK644388D0 (da)	1988-11-18	Farmaceutiske praeparater indeholdende 3-hydroxy-smoeresyrederivater
DK199789A (da)	1989-10-27	Anvendelse af et phenylquinolincarboxylsyrederivat eller et farmaceutisk egnet salt deraf til fremstilling af et topisk farmaceutisk praeparat til behandling af hud- og/eller slimepithelsygdomme
FI891986A7 (fi)	1989-04-26	Farmaseuttiset koostumukset psoriasiksen hoitoon
NO883074D0 (no)	1988-07-08	Fremgangsmaate til fremstilling av 3-desmetyl-4-fluor-mevalonsyrederivater.
FI913131A0 (fi)	1991-06-27	Nya 3,3'-ditiobis (propionsyror)och deras estrar.
FI920018A7 (fi)	1992-07-05	Menetelmä 3-eksometyleenikefaamisulfoksidiestereiden valmistamiseksi
IT1197516B (it)	1988-11-30	Derivati teofillinmetilanici e teofillinmetilditianici procedimento per la loro preparazione e composizioni farmaceutiche che li comprendono
ATE86974T1 (de)	1993-04-15	(2-cyan-2-oximinoacetyl)-aminosaeure-derivate.
FI925546A7 (fi)	1992-12-07	Amidiliittyneitä pyridyylihappojohdannaisia leukotrieeniin liittyvien sairauksien hoitamiseksi
FI880385A0 (fi)	1988-01-28	Substituerade 3-fenyl-7h-tiazolo /3,2-b//1,2,4/-triazin-7-oner, foerfaranden foer deras framstaellning, dessa innehaollande laekemedel och deras anvaendning, samt naogra vid framstaellningen av naemnda foereningar bildade mellanprodukter.
ITMI920539A0 (it)	1992-03-10	Procedimento per la separazione dell'acido ftalimmido perossicaproico da soluzioni di solventi organici
WO1987004435A3 (en)	1988-03-24	Xanthine compounds
DK0440100T3 (da)	1994-11-21	Anvendelse af et galdesyresalt og et lipid
IT8720701A0 (it)	1987-05-28	Composizioni farmaceutiche adattivita' immunomodulante.
DK163432C (da)	1992-07-20	Analogifremgangsmaade til fremstilling af oe1,2,4aatriazolo-oe4,3-aaaquinoxalin-4-amin-derivater eller farmaceutisk acceptable syreadditionssalte deraf
IT8719949A0 (it)	1987-04-02	Composizioni farmaceutiche adattivita' immunomodulante.

Legal Events

Date	Code	Title	Description
1995-08-28	B1	Patent granted (law 1993)
1999-11-29	PBP	Patent lapsed