DK2010648T3 - Delta-17-desaturaser og anvendelse heraf i fremstillingen af flerumættede fedtsyrer - Google Patents
Delta-17-desaturaser og anvendelse heraf i fremstillingen af flerumættede fedtsyrerInfo
- Publication number
- DK2010648T3 DK2010648T3 DK07775772.2T DK07775772T DK2010648T3 DK 2010648 T3 DK2010648 T3 DK 2010648T3 DK 07775772 T DK07775772 T DK 07775772T DK 2010648 T3 DK2010648 T3 DK 2010648T3
- Authority
- DK
- Denmark
- Prior art keywords
- desaturases
- fatty acids
- delta17
- polyunsaturated fatty
- delta
- Prior art date
Links
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 title abstract 2
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 abstract 2
- 235000020673 eicosapentaenoic acid Nutrition 0.000 abstract 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 abstract 1
- 235000021342 arachidonic acid Nutrition 0.000 abstract 1
- 229940114079 arachidonic acid Drugs 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 229960005135 eicosapentaenoic acid Drugs 0.000 abstract 1
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 235000020978 long-chain polyunsaturated fatty acids Nutrition 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 1
- 235000020660 omega-3 fatty acid Nutrition 0.000 abstract 1
- 235000020665 omega-6 fatty acid Nutrition 0.000 abstract 1
- 229940033080 omega-6 fatty acid Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6432—Eicosapentaenoic acids [EPA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0083—Miscellaneous (1.14.99)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0083—Miscellaneous (1.14.99)
- C12N9/0087—Steroid 21-monooxygenase (1.14.99.10)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nutrition Science (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79357506P | 2006-04-20 | 2006-04-20 | |
| PCT/US2007/009572 WO2007123999A2 (en) | 2006-04-20 | 2007-04-19 | Δ17 desaturases and their use in making polyunsaturated fatty acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2010648T3 true DK2010648T3 (da) | 2012-05-21 |
Family
ID=38625589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07775772.2T DK2010648T3 (da) | 2006-04-20 | 2007-04-19 | Delta-17-desaturaser og anvendelse heraf i fremstillingen af flerumættede fedtsyrer |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7465793B2 (da) |
| EP (1) | EP2010648B1 (da) |
| JP (1) | JP2009534032A (da) |
| CN (1) | CN101646766B (da) |
| AT (1) | ATE542892T1 (da) |
| AU (1) | AU2007240741B2 (da) |
| DK (1) | DK2010648T3 (da) |
| MX (1) | MX2008013306A (da) |
| WO (1) | WO2007123999A2 (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2500420B1 (en) * | 2006-08-24 | 2016-06-22 | BASF Plant Science GmbH | Pythium omega 3 desaturase with specificity to all omega 6 fatty acids longer than 18 carbon chains |
| EP2087105B1 (en) | 2006-10-30 | 2015-02-25 | E.I. Du Pont De Nemours And Company | Delta 17 desaturase and its use in making polyunsaturated fatty acids |
| US7709239B2 (en) * | 2006-12-07 | 2010-05-04 | E.I. Du Pont De Nemours And Company | Mutant Δ8 desaturase genes engineered by targeted mutagenesis and their use in making polyunsaturated fatty acids |
| US7794701B2 (en) * | 2007-04-16 | 2010-09-14 | E.I. Du Pont De Nemours And Company | Δ-9 elongases and their use in making polyunsaturated fatty acids |
| WO2010045324A1 (en) * | 2008-10-14 | 2010-04-22 | Monsanto Technology Llc | Utilization of fatty acid desaturases from hemiselmis spp. |
| EP2669380B1 (en) * | 2008-12-12 | 2017-09-27 | BASF Plant Science GmbH | Desaturases and process for the production of polyunsaturated fatty acids in transgenic organisms |
| US8980589B2 (en) * | 2010-08-26 | 2015-03-17 | E I Du Pont De Nemours And Company | Mutant delta-9 elongases and their use in making polyunsaturated fatty acids |
| WO2015029966A1 (ja) | 2013-08-27 | 2015-03-05 | 国立大学法人京都大学 | ω３不飽和脂肪酸酵素およびエイコサペンタエン酸の製造方法 |
| JP6026709B1 (ja) * | 2014-12-25 | 2016-11-16 | 国立大学法人京都大学 | 新規ω３不飽和脂肪酸酵素およびエイコサペンタエン酸の製造方法 |
| CN105368851B (zh) * | 2015-12-09 | 2019-05-07 | 江南大学 | 一种来源于寄生疫霉的ω-3脱饱和酶、含所述脱饱和酶的载体、重组微生物及其应用 |
| WO2017097218A1 (zh) * | 2015-12-09 | 2017-06-15 | 江南大学 | 来源于寄生疫霉的用于合成多不饱和脂肪酸的ω-3脂肪酸脱饱和酶、含所述脂肪酸脱饱和酶的载体、重组微生物及其应用 |
| CN106916796B (zh) * | 2015-12-28 | 2021-06-29 | 丰益(上海)生物技术研发中心有限公司 | 裂殖壶菌delta-12脂肪酸脱饱和酶相关序列及其应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US7008664B1 (en) * | 1998-06-11 | 2006-03-07 | E. I. Du Pont De Nemours And Company | Method for improving the carcass quality of an animal |
| US6635451B2 (en) | 2001-01-25 | 2003-10-21 | Abbott Laboratories | Desaturase genes and uses thereof |
| US7125672B2 (en) | 2003-05-07 | 2006-10-24 | E. I. Du Pont De Nemours And Company | Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts |
| US7238482B2 (en) | 2003-05-07 | 2007-07-03 | E. I. Du Pont De Nemours And Company | Production of polyunsaturated fatty acids in oleaginous yeasts |
| EP2166067B1 (de) | 2003-08-01 | 2015-07-01 | BASF Plant Science GmbH | Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Organismen |
| EP1682566B1 (en) | 2003-11-12 | 2013-06-05 | E.I. Du Pont De Nemours And Company | Delta-15 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous plants and yeast |
| EP1720988B1 (de) | 2004-02-27 | 2011-10-12 | BASF Plant Science GmbH | Verfahren zur herstellung von ungesättigten omega-3-fettsäuren in transgenen organismen |
| WO2005083093A2 (de) | 2004-02-27 | 2005-09-09 | Basf Plant Science Gmbh | Verfahren zur herstellung mehrfach ungesättigter fettsäuren in transgenen pflanzen |
| US7588931B2 (en) | 2004-11-04 | 2009-09-15 | E. I. Du Pont De Nemours And Company | High arachidonic acid producing strains of Yarrowia lipolytica |
| US7189559B2 (en) | 2004-11-04 | 2007-03-13 | E. I. Du Pont De Nemours And Company | Mortierella alpina lysophosphatidic acid acyltransferase homolog for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms |
| US7192762B2 (en) | 2004-11-04 | 2007-03-20 | E. I. Du Pont De Nemours And Company | Mortierella alpina glycerol-3-phosphate o-acyltransferase for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms |
| DE102005013779A1 (de) | 2005-03-22 | 2006-09-28 | Basf Plant Science Gmbh | Verfahren zur Herstellung von mehrfach ungesättigten C20- und C22-Fettsäuren mit mindestens vier Doppelbindungen in transgenen Pflanzen |
-
2007
- 2007-04-18 US US11/787,772 patent/US7465793B2/en not_active Expired - Fee Related
- 2007-04-19 EP EP07775772A patent/EP2010648B1/en not_active Not-in-force
- 2007-04-19 AU AU2007240741A patent/AU2007240741B2/en not_active Ceased
- 2007-04-19 WO PCT/US2007/009572 patent/WO2007123999A2/en not_active Ceased
- 2007-04-19 MX MX2008013306A patent/MX2008013306A/es not_active Application Discontinuation
- 2007-04-19 JP JP2009506580A patent/JP2009534032A/ja not_active Ceased
- 2007-04-19 AT AT07775772T patent/ATE542892T1/de active
- 2007-04-19 CN CN2007800139991A patent/CN101646766B/zh not_active Expired - Fee Related
- 2007-04-19 DK DK07775772.2T patent/DK2010648T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007123999A3 (en) | 2008-04-24 |
| WO2007123999A2 (en) | 2007-11-01 |
| EP2010648A2 (en) | 2009-01-07 |
| JP2009534032A (ja) | 2009-09-24 |
| ATE542892T1 (de) | 2012-02-15 |
| AU2007240741A1 (en) | 2007-11-01 |
| CN101646766B (zh) | 2013-03-27 |
| US20070249026A1 (en) | 2007-10-25 |
| AU2007240741B2 (en) | 2013-01-31 |
| CN101646766A (zh) | 2010-02-10 |
| US7465793B2 (en) | 2008-12-16 |
| EP2010648B1 (en) | 2012-01-25 |
| MX2008013306A (es) | 2008-10-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2007123999A3 (en) | Δ17 desaturases and their use in making polyunsaturated fatty acids | |
| WO2007136671A3 (en) | Delta5 desaturase and its use in making polyunsaturated fatty acids | |
| WO2007136646A3 (en) | Delta5 desaturase and its use in making polyunsaturated fatty acids | |
| WO2010033753A3 (en) | Mutant delta5 desaturases and their use in making polyunsaturated fatty acids | |
| EP2392664A3 (en) | Production of polyunsaturated fatty acids in oleaginous yeasts | |
| WO2008124806A3 (en) | Delta-8 desaturases and their use in making polyunsaturated fatty acids | |
| BRPI0418921A (pt) | uso de ácidos graxos poliinsaturados, composição nutricional, e, uso de uma composição | |
| MXPA03000750A (es) | Genes de elongasa y usos de los mismos. | |
| EP1682567A4 (en) | DELTA12 DESATURASES WHICH CAN BE USED TO MODIFY POLYUNSATURATED FATTY ACID LEVELS IN OLEAGINOUS YEAST | |
| MX342029B (es) | Metodo para la produccion de acidos grasos poli - insaturados en organismos transgenicos. | |
| DK1480993T3 (da) | Desaturasegener, enzymer kodet heraf og anvendelser heraf | |
| WO2008063340A3 (en) | Delta-8 desaturases and their use in making polyunsaturated fatty acids | |
| MX2011011842A (es) | Composiciones, metodos y equipos para acidos grasos poliinsaturados a partir de microalgas. | |
| BR0311324A (pt) | Dessaturases de ácidos graxos de fungos | |
| EP1682566A4 (en) | TO MODIFY THE MIRRORS OF MULTIPLE-UNSATURATED FATTY ACIDS IN OIL-DELIVERY PLANTS AND YEAST-LIKE DELTA-15 DESATURASE | |
| BRPI0413786A (pt) | ácido graxo dessaturases de primula | |
| WO2007061845A3 (en) | Delta-9 elongases and their use in making polyunsaturated fatty acids | |
| WO2004057001A3 (en) | Method for the production of polyunsaturated fatty acids | |
| WO2004001001A3 (en) | Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids | |
| WO2006052870A3 (en) | High eicosapentaenoic acid producing strains of yarrowia lipolytica | |
| BRPI1009690A2 (pt) | "célula hospedeira microbiana oleaginosa, óleo, método de elaboração de um óleo, método de aumento da eficiência de conversão de alongamento de c18 para c20 em uma célula hospedeira recombinante microbiana oleaginosa e método de aumento da eficiência de conversão de dessaturação (delta) 4 em uma célula hospedeira recombinante microbiana oleaginosa produtora de ácidos graxos póli-insaturados de cadeia longa" | |
| AR073855A1 (es) | Utilizacion de desaturasas de acidos grasos de hemiselmis spp. | |
| ATE538198T1 (de) | Elongasegene und deren verwendungen | |
| EP2450434A3 (en) | Process for the production of arachidonic acid and/or eicosapentaenoic acid | |
| AU2016202449A1 (en) | Desaturases and process for the production of polyunsaturated fatty acids in transgenic organisms |