DK203990D0 - Piperazinylderivater - Google Patents
PiperazinylderivaterInfo
- Publication number
- DK203990D0 DK203990D0 DK203990A DK203990A DK203990D0 DK 203990 D0 DK203990 D0 DK 203990D0 DK 203990 A DK203990 A DK 203990A DK 203990 A DK203990 A DK 203990A DK 203990 D0 DK203990 D0 DK 203990D0
- Authority
- DK
- Denmark
- Prior art keywords
- receptor
- alkyl
- hydrogen
- image
- various
- Prior art date
Links
- 125000004193 piperazinyl group Chemical group 0.000 title abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 102000005962 receptors Human genes 0.000 abstract 2
- 108020003175 receptors Proteins 0.000 abstract 2
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 1
- -1 2-diazanaphthyl Chemical group 0.000 abstract 1
- 102000056834 5-HT2 Serotonin Receptors Human genes 0.000 abstract 1
- 108091005479 5-HT2 receptors Proteins 0.000 abstract 1
- 102100022738 5-hydroxytryptamine receptor 1A Human genes 0.000 abstract 1
- 101710138638 5-hydroxytryptamine receptor 1A Proteins 0.000 abstract 1
- 102000015554 Dopamine receptor Human genes 0.000 abstract 1
- 108050004812 Dopamine receptor Proteins 0.000 abstract 1
- 208000018522 Gastrointestinal disease Diseases 0.000 abstract 1
- 210000000748 cardiovascular system Anatomy 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/66—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Quinoline Compounds (AREA)
Priority Applications (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK203990A DK203990D0 (da) | 1990-08-24 | 1990-08-24 | Piperazinylderivater |
| US07/744,556 US5246935A (en) | 1990-08-24 | 1991-08-13 | Piperazinyl derivatives and methods of treating central nervous system ailments relating to the 5-ht2 receptor system |
| IL9921191A IL99211A (en) | 1990-08-24 | 1991-08-16 | Piperaziny derivatives their preparation and pharmaceutical compositions containing them |
| NZ23950291A NZ239502A (en) | 1990-08-24 | 1991-08-22 | Di-aryl piperazine derivatives, preparation and pharmaceutical compositions thereof. |
| ZA916652A ZA916652B (en) | 1990-08-24 | 1991-08-22 | Piperazinyl derivatives |
| JP3514325A JPH06500546A (ja) | 1990-08-24 | 1991-08-23 | ピペラジニル誘導体 |
| AT91915381T ATE125802T1 (de) | 1990-08-24 | 1991-08-23 | Piperazinylderivate mit affinität zu 5-ht rezeptoren. |
| DK91915381.7T DK0544765T3 (da) | 1990-08-24 | 1991-08-23 | Piperazinylderivater med affinitet for 5-HT-receptorer |
| DE69111815T DE69111815T2 (de) | 1990-08-24 | 1991-08-23 | Piperazinylderivate mit Affinität zu 5-HT Rezeptoren. |
| AU84413/91A AU653956B2 (en) | 1990-08-24 | 1991-08-23 | Piperazinyl derivatives |
| IE298391A IE73475B1 (en) | 1990-08-24 | 1991-08-23 | Piperanzinyl derivatives with affinity for 5-HT receptors |
| PCT/DK1991/000244 WO1992003426A1 (en) | 1990-08-24 | 1991-08-23 | Piperazinyl derivatives |
| PT98768A PT98768B (pt) | 1990-08-24 | 1991-08-23 | Processo de preparacao de derivados de piperazinilo e de composicoes farmaceuticas que os contem |
| CA002089768A CA2089768A1 (en) | 1990-08-24 | 1991-08-23 | Piperazinyl derivatives |
| FI930799A FI930799L (fi) | 1990-08-24 | 1991-08-23 | Piperazinylderivat |
| EP91915381A EP0544765B1 (de) | 1990-08-24 | 1991-08-23 | Piperazinylderivate mit Affinität zu 5-HT Rezeptoren |
| NO93930631A NO930631L (no) | 1990-08-24 | 1993-02-23 | Piperazinylderivater |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK203990A DK203990D0 (da) | 1990-08-24 | 1990-08-24 | Piperazinylderivater |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK203990D0 true DK203990D0 (da) | 1990-08-24 |
Family
ID=8109641
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK203990A DK203990D0 (da) | 1990-08-24 | 1990-08-24 | Piperazinylderivater |
| DK91915381.7T DK0544765T3 (da) | 1990-08-24 | 1991-08-23 | Piperazinylderivater med affinitet for 5-HT-receptorer |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91915381.7T DK0544765T3 (da) | 1990-08-24 | 1991-08-23 | Piperazinylderivater med affinitet for 5-HT-receptorer |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5246935A (de) |
| EP (1) | EP0544765B1 (de) |
| JP (1) | JPH06500546A (de) |
| AT (1) | ATE125802T1 (de) |
| AU (1) | AU653956B2 (de) |
| CA (1) | CA2089768A1 (de) |
| DE (1) | DE69111815T2 (de) |
| DK (2) | DK203990D0 (de) |
| FI (1) | FI930799L (de) |
| IE (1) | IE73475B1 (de) |
| IL (1) | IL99211A (de) |
| NO (1) | NO930631L (de) |
| NZ (1) | NZ239502A (de) |
| PT (1) | PT98768B (de) |
| WO (1) | WO1992003426A1 (de) |
| ZA (1) | ZA916652B (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5364849A (en) * | 1989-04-22 | 1994-11-15 | John Wyeth & Brother, Limited | 1-[3 or 4-[1-[4-piperazinyl]]-2 arylpropionyl or butryl]-heterocyclic derivatives |
| US5436246A (en) * | 1992-09-17 | 1995-07-25 | Merrell Dow Pharmaceuticals Inc. | Serotonin receptor agents |
| DK148392D0 (da) * | 1992-12-09 | 1992-12-09 | Lundbeck & Co As H | Heterocykliske forbindelser |
| GB9300195D0 (en) * | 1993-01-06 | 1993-03-03 | Wyeth John & Brother Ltd | Piperazine derivatives |
| US5453425A (en) * | 1994-07-11 | 1995-09-26 | Janssen Pharmaceutica N.V. | Risperidone oral formulation |
| CN1494907A (zh) * | 1996-03-25 | 2004-05-12 | 治疗疼痛的药物组合物 | |
| WO1997035584A1 (en) * | 1996-03-25 | 1997-10-02 | Eli Lilly And Company | Method for treating pain |
| IL126064A0 (en) * | 1996-03-25 | 1999-05-09 | Lilly Co Eli | Method for treating pain |
| FR2753968B1 (fr) * | 1996-09-27 | 1998-11-27 | Sod Conseils Rech Applic | Nouvelles heteroaryloxyethylamines, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
| US6344458B1 (en) | 1998-12-17 | 2002-02-05 | American Home Products Corporation | Piperazine ethylamide derivatives |
| AU2001239827A1 (en) | 2000-02-22 | 2001-09-03 | Cv Therapeutics, Inc. | Substituted alkylene diamine compounds |
| WO2001085168A1 (en) * | 2000-05-12 | 2001-11-15 | Solvay Pharmaceuticals B.V. | Use of compounds having combined dopamine d2, 5-ht1a and alpha adrenoreceptor agonistic action for treating cns disorders |
| FR2821356A1 (fr) * | 2001-02-23 | 2002-08-30 | Cerep | Nouveaux derives d'arylcarbamates et d'arylurees, preparations et utilisations |
| SE0103648D0 (sv) * | 2001-11-01 | 2001-11-01 | Astrazeneca Ab | Therapeutic quinolone compounds |
| SE0103649D0 (sv) * | 2001-11-01 | 2001-11-01 | Astrazeneca Ab | Therapeutic quinoline compounds |
| US6750367B2 (en) * | 2002-05-09 | 2004-06-15 | Bayer Polymers Llc | Tetralin isocyanates |
| MXPA05001631A (es) | 2002-08-12 | 2005-08-19 | Takeda Pharmaceutical | Derivado de benceno fusionado y su uso. |
| JP2009527562A (ja) * | 2006-02-21 | 2009-07-30 | アムゲン インコーポレイティッド | ホスホジエステラーゼ１０阻害剤としてのシンノリン誘導体 |
| DK2400968T3 (da) * | 2009-02-26 | 2017-01-02 | Reviva Pharmaceuticals Inc | Sammensætninger, syntese og fremgangsmåder til anvendelse af arylpiperazinderivater |
| CN104884064A (zh) | 2012-12-24 | 2015-09-02 | 纽洛佳斯特拉斯公司 | 用于治疗胃肠道病症的方法 |
| US9844554B2 (en) | 2014-06-24 | 2017-12-19 | Neurogastrx, Inc. | Prodrugs of metopimazine |
| MA41168A (fr) * | 2014-12-17 | 2017-10-24 | Acraf | Nouveaux composés antibactériens |
| JP7017797B2 (ja) * | 2017-02-24 | 2022-02-09 | 深▲チェン▼市霊蘭生物医薬科技有限公司 | 新規なドーパミンｄ３受容体選択的リガンド及びびその調製方法並びに医薬使用 |
| US10836757B1 (en) | 2020-04-02 | 2020-11-17 | Neurogastrx, Inc. | Polymorphic forms of metopimazine |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2836595A (en) * | 1958-05-27 | Piperazine derivatives and process for | ||
| CA683208A (en) * | 1964-03-31 | Hayao Shin | Phenylpiperazinylalkyl esters and amides | |
| US3138597A (en) * | 1964-06-23 | Phenylpiperazinylalkyl carbamates | ||
| GB952142A (en) * | 1961-05-26 | 1964-03-11 | Miles Lab | Phenylpiperazinylalkyl carbamates |
| US4202898A (en) * | 1978-06-05 | 1980-05-13 | Synthelabo | Method of treating anxiety and depression |
| AU532411B2 (en) * | 1979-03-01 | 1983-09-29 | Duphar International Research B.V. | Phenyl piperazine derivatives |
| GB8303946D0 (en) * | 1983-02-12 | 1983-03-16 | Recordati Chem Pharm | Antihypertensive n-piperazinylalkanoylanilides |
| US4882432A (en) * | 1989-01-09 | 1989-11-21 | American Home Products Corporation | Polycyclic-carbamic acid piperazinoalkyl esters and amides |
| ES2076253T3 (es) * | 1989-05-19 | 1995-11-01 | Hoechst Roussel Pharma | N-(ariloxialquil)-heteroarilpiperidinas y -heteroarilpiperazinas, un procedimiento para su preparacion y su uso como medicamentos. |
| FR2655988B1 (fr) * | 1989-12-20 | 1994-05-20 | Adir Cie | Nouveaux derives de la napht-1-yl piperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
-
1990
- 1990-08-24 DK DK203990A patent/DK203990D0/da not_active Application Discontinuation
-
1991
- 1991-08-13 US US07/744,556 patent/US5246935A/en not_active Expired - Fee Related
- 1991-08-16 IL IL9921191A patent/IL99211A/en active IP Right Grant
- 1991-08-22 NZ NZ23950291A patent/NZ239502A/en unknown
- 1991-08-22 ZA ZA916652A patent/ZA916652B/xx unknown
- 1991-08-23 IE IE298391A patent/IE73475B1/en not_active IP Right Cessation
- 1991-08-23 AU AU84413/91A patent/AU653956B2/en not_active Ceased
- 1991-08-23 PT PT98768A patent/PT98768B/pt not_active IP Right Cessation
- 1991-08-23 EP EP91915381A patent/EP0544765B1/de not_active Expired - Lifetime
- 1991-08-23 JP JP3514325A patent/JPH06500546A/ja active Pending
- 1991-08-23 DK DK91915381.7T patent/DK0544765T3/da active
- 1991-08-23 CA CA002089768A patent/CA2089768A1/en not_active Abandoned
- 1991-08-23 FI FI930799A patent/FI930799L/fi not_active Application Discontinuation
- 1991-08-23 WO PCT/DK1991/000244 patent/WO1992003426A1/en not_active Ceased
- 1991-08-23 DE DE69111815T patent/DE69111815T2/de not_active Expired - Fee Related
- 1991-08-23 AT AT91915381T patent/ATE125802T1/de not_active IP Right Cessation
-
1993
- 1993-02-23 NO NO93930631A patent/NO930631L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI930799A0 (fi) | 1993-02-23 |
| ATE125802T1 (de) | 1995-08-15 |
| JPH06500546A (ja) | 1994-01-20 |
| NZ239502A (en) | 1994-07-26 |
| IE912983A1 (en) | 1992-02-26 |
| DK0544765T3 (da) | 1995-12-27 |
| FI930799A7 (fi) | 1993-02-23 |
| PT98768A (pt) | 1992-07-31 |
| PT98768B (pt) | 1999-01-29 |
| NO930631L (no) | 1993-04-23 |
| IE73475B1 (en) | 1997-06-04 |
| US5246935A (en) | 1993-09-21 |
| IL99211A0 (en) | 1992-07-15 |
| DE69111815T2 (de) | 1996-04-18 |
| IL99211A (en) | 1996-01-31 |
| EP0544765B1 (de) | 1995-08-02 |
| NO930631D0 (no) | 1993-02-23 |
| AU653956B2 (en) | 1994-10-20 |
| EP0544765A1 (de) | 1993-06-09 |
| AU8441391A (en) | 1992-03-17 |
| DE69111815D1 (de) | 1995-09-07 |
| WO1992003426A1 (en) | 1992-03-05 |
| FI930799L (fi) | 1993-02-23 |
| ZA916652B (en) | 1992-05-27 |
| CA2089768A1 (en) | 1992-02-25 |
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