DK2082225T3 - Fremgangsmåde til bestemmelse af, om en tumorcelle har invasivt og/eller metastatisk potentiale, og midler tilmodulering af malign transformation - Google Patents
Fremgangsmåde til bestemmelse af, om en tumorcelle har invasivt og/eller metastatisk potentiale, og midler tilmodulering af malign transformationInfo
- Publication number
- DK2082225T3 DK2082225T3 DK07823920.9T DK07823920T DK2082225T3 DK 2082225 T3 DK2082225 T3 DK 2082225T3 DK 07823920 T DK07823920 T DK 07823920T DK 2082225 T3 DK2082225 T3 DK 2082225T3
- Authority
- DK
- Denmark
- Prior art keywords
- invasive
- determining whether
- tumor cell
- metastatic potential
- malignant transformation
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57515—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the breast
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0618486.5A GB0618486D0 (en) | 2006-09-20 | 2006-09-20 | Assay |
| GB0625379A GB0625379D0 (en) | 2006-12-20 | 2006-12-20 | Assay |
| PCT/GB2007/003599 WO2008035096A1 (en) | 2006-09-20 | 2007-09-20 | Assay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2082225T3 true DK2082225T3 (da) | 2014-04-07 |
Family
ID=38988374
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07823920.9T DK2082225T3 (da) | 2006-09-20 | 2007-09-20 | Fremgangsmåde til bestemmelse af, om en tumorcelle har invasivt og/eller metastatisk potentiale, og midler tilmodulering af malign transformation |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8609332B2 (da) |
| EP (1) | EP2082225B1 (da) |
| DK (1) | DK2082225T3 (da) |
| ES (1) | ES2453374T3 (da) |
| PL (1) | PL2082225T3 (da) |
| PT (1) | PT2082225E (da) |
| WO (1) | WO2008035096A1 (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2904960A1 (en) | 2013-03-14 | 2014-10-02 | University Of Florida Research Foundation, Inc. | Di-amino acid repeat-containing proteins associated with als |
| US10509045B2 (en) | 2015-05-29 | 2019-12-17 | University Of Florida Research Foundation, Incorporated | Methods for diagnosing Huntington's disease |
| US10940161B2 (en) | 2016-04-04 | 2021-03-09 | University Of Florida Research Foundation, Incorporated | Manipulation of EIF3 to modulate repeat associated non-ATG (RAN) translation |
| CA3060250A1 (en) | 2017-04-17 | 2018-10-25 | University Of Florida Research Foundation, Incorporated | Regulation of ran protein translation by pkr and eif2a-p pathways |
| US12504380B2 (en) * | 2017-09-25 | 2025-12-23 | University Of Florida Research Foundation, Incorporated | Immunoassays for detection of ran proteins |
| JP7350337B2 (ja) | 2017-09-26 | 2023-09-26 | ユニバーシティー オブ フロリダ リサーチ ファンデーション, インク. | 神経障害の処置においてranタンパク質レベルを低下させるためのメトホルミンおよびそのアナログの使用 |
| WO2021055880A1 (en) | 2019-09-20 | 2021-03-25 | University Of Florida Researchfoundation, Incorporated | Detection of antibodies against ran proteins from serum and tissue lysates |
| GB201915598D0 (en) * | 2019-10-28 | 2019-12-11 | Univ Bradford | Methods for determining the invasive and/or metastic potential of a tumour |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6613534B2 (en) * | 2001-03-20 | 2003-09-02 | Wake Forest University Health Sciences | MAP-2 as a determinant of metastatic potential |
| US20040219572A1 (en) | 2002-12-17 | 2004-11-04 | Jie Chen | Specific markers for pancreatic cancer |
| EP1677733A4 (en) | 2003-10-03 | 2007-09-19 | Bayer Pharmaceuticals Corp | GENE EXPRESSION PROFILES AND METHOD OF USE |
| US7521195B1 (en) * | 2005-07-21 | 2009-04-21 | Celera Corporation | Lung disease targets and uses thereof |
-
2007
- 2007-09-20 EP EP07823920.9A patent/EP2082225B1/en not_active Not-in-force
- 2007-09-20 PT PT78239209T patent/PT2082225E/pt unknown
- 2007-09-20 ES ES07823920.9T patent/ES2453374T3/es active Active
- 2007-09-20 WO PCT/GB2007/003599 patent/WO2008035096A1/en not_active Ceased
- 2007-09-20 DK DK07823920.9T patent/DK2082225T3/da active
- 2007-09-20 US US12/311,192 patent/US8609332B2/en not_active Expired - Fee Related
- 2007-09-20 PL PL07823920T patent/PL2082225T3/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2082225A1 (en) | 2009-07-29 |
| EP2082225B1 (en) | 2014-01-01 |
| PT2082225E (pt) | 2014-04-10 |
| WO2008035096A1 (en) | 2008-03-27 |
| US20090312395A1 (en) | 2009-12-17 |
| US8609332B2 (en) | 2013-12-17 |
| PL2082225T3 (pl) | 2014-06-30 |
| ES2453374T3 (es) | 2014-04-07 |
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