DK209289A - Fremgangsmaade til fremstilling af indol-3-carboxylsyreestere af trans-hexahydro-8-hydroxy-2,6-methano-2h-quinolin-3(4h)-on - Google Patents

Fremgangsmaade til fremstilling af indol-3-carboxylsyreestere af trans-hexahydro-8-hydroxy-2,6-methano-2h-quinolin-3(4h)-on Download PDF

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Publication number
DK209289A
DK209289A DK209289A DK209289A DK209289A DK 209289 A DK209289 A DK 209289A DK 209289 A DK209289 A DK 209289A DK 209289 A DK209289 A DK 209289A DK 209289 A DK209289 A DK 209289A
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DK
Denmark
Prior art keywords
methano
quinolin
hexahydro
trans
hydroxy
Prior art date
Application number
DK209289A
Other languages
English (en)
Other versions
DK209289D0 (da
Inventor
Peter B Anzeveno
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of DK209289D0 publication Critical patent/DK209289D0/da
Publication of DK209289A publication Critical patent/DK209289A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK209289A 1988-04-29 1989-04-28 Fremgangsmaade til fremstilling af indol-3-carboxylsyreestere af trans-hexahydro-8-hydroxy-2,6-methano-2h-quinolin-3(4h)-on DK209289A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18823288A 1988-04-29 1988-04-29

Publications (2)

Publication Number Publication Date
DK209289D0 DK209289D0 (da) 1989-04-28
DK209289A true DK209289A (da) 1989-10-30

Family

ID=22692288

Family Applications (1)

Application Number Title Priority Date Filing Date
DK209289A DK209289A (da) 1988-04-29 1989-04-28 Fremgangsmaade til fremstilling af indol-3-carboxylsyreestere af trans-hexahydro-8-hydroxy-2,6-methano-2h-quinolin-3(4h)-on

Country Status (7)

Country Link
EP (1) EP0339669A1 (da)
JP (1) JPH01313477A (da)
KR (1) KR890016044A (da)
DK (1) DK209289A (da)
HU (1) HU201754B (da)
IL (1) IL90107A0 (da)
ZA (1) ZA893008B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006056081A1 (de) * 2004-11-25 2006-06-01 Cilag Ltd. Verfahren zur herstellung von estern von hexahydro-8-hydroxy-2,6-methano-2h-chinolizin-3(4h)-on
ES2264901B1 (es) 2005-07-06 2007-12-01 Inke, S.A. Procedimiento para la obtencion de un compuesto farmaceuticamente activo, sus intermedios de sintesis y procedimiento para la obtencion de los mismos.
WO2007003522A1 (en) * 2005-07-06 2007-01-11 Inke, S.A. Method for obtaining a pharmaceutically active compound, synthesis intermediates thereof and methods for obtaining them
WO2007072507A2 (en) * 2005-12-23 2007-06-28 Usv Limited Polymorphic forms of dolasetron base and processes of preparing dolasetron base, its polymorphic forms and salt thereof
WO2007081909A2 (en) 2006-01-05 2007-07-19 Teva Gyogyszergyar Zartkoruen Mukodo Forms of dolasetron mesylate and processes for their preparation
US20090062546A1 (en) * 2007-07-20 2009-03-05 Janos Hajko Dolasetron trifluoroacetate, polymorphs of dolasetron trifluoroacetate and process for preparation thereof
EP2060557B1 (en) 2007-11-13 2012-06-06 Inke, S.A. Intermediate compounds useful to prepare dolasetron
CN102180878B (zh) * 2010-07-02 2013-06-26 成都新恒创药业有限公司 一种多拉司琼异构体或其盐及其制备方法和其应用
CN109503580A (zh) * 2019-01-15 2019-03-22 南京恩泰医药科技有限公司 一种甲磺酸多拉司琼晶型及制备方法
CN113501820A (zh) * 2021-07-20 2021-10-15 南京恩泰医药科技有限公司 一种多拉司琼关键中间体hqo的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA878096B (en) * 1986-11-03 1988-04-26 Merrell Dow Pharmaceuticals Inc. Esters of hexahydro-8-hydroxy-2,6-methano-2h-quinolizin-3(4h)-one and related compounds

Also Published As

Publication number Publication date
JPH01313477A (ja) 1989-12-18
KR890016044A (ko) 1989-11-28
EP0339669A1 (en) 1989-11-02
DK209289D0 (da) 1989-04-28
ZA893008B (en) 1989-12-27
HUT50173A (en) 1989-12-28
HU201754B (en) 1990-12-28
IL90107A0 (en) 1989-12-15

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AHB Application shelved due to non-payment