DK2100959T3 - Pattedyrscytokin: Interleukin-B30 og tilhørende reagenser - Google Patents

Pattedyrscytokin: Interleukin-B30 og tilhørende reagenser Download PDF

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Publication number
DK2100959T3
DK2100959T3 DK09156327.0T DK09156327T DK2100959T3 DK 2100959 T3 DK2100959 T3 DK 2100959T3 DK 09156327 T DK09156327 T DK 09156327T DK 2100959 T3 DK2100959 T3 DK 2100959T3
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DK
Denmark
Prior art keywords
leu
gin
ala
ser
pro
Prior art date
Application number
DK09156327.0T
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English (en)
Inventor
J Fernando Bazan
Original Assignee
Merck Sharp & Dohme
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25413278&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2100959(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
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Publication of DK2100959T3 publication Critical patent/DK2100959T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Claims (7)

1. Antistof, eller antigenbindende fragment deraf, som specifikt binder til den modne aminosyresekvens SEQ ID NO.: 2 eller 4 eller en variant deraf med 1, 2, 3, 5 eller 7 konservative aminosyresubstitutioner.
2. Antistof, eller antigenbindende fragment deraf, ifølge krav 1, hvor antistoffet specifikt binder til den modne aminosyresekvens SEQ ID NO.: 2 eller en variant deraf med 1, 2, 3, 5 eller 7 konservative aminosyresubstitutioner.
3. Antistof, eller antigenbindende fragment deraf, ifølge krav 2, hvor antistoffet, eller det antigenbindende fragment deraf, er et monoklonalt antistof eller fragment deraf.
4. Antistof, eller antigenbindende fragment deraf, ifølge krav 2, hvor antistoffet eller det antigenbindende fragment er: a) et Fab-fragment; b) et Fab'-fragment; c) et F(ab)2-fragment; eller d) et enkelt kædeantistof.
5. Antistof, eller antigenbindende fragment deraf, ifølge krav 2, hvor antistoffet, eller det antigenbindende fragment deraf, er et kimærisk eller humaniseret antistof, eller et antigenbindende fragment deraf.
6. Steril sammensætning omfattende antistoffet, eller det antigenbindende fragment deraf, ifølge et af kravene 1-5.
7. Farmaceutisk formulering omfattende: a) antistoffet, eller det antigenbindende fragment deraf, ifølge et af kravene 1-5; og b) en eller flere farmaceutisk acceptable bærere.
DK09156327.0T 1997-07-25 1998-07-24 Pattedyrscytokin: Interleukin-B30 og tilhørende reagenser DK2100959T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90090597A 1997-07-25 1997-07-25
EP98937105A EP1002084B1 (en) 1997-07-25 1998-07-24 Mammalian cytokine: interleukin-b30 and related reagents

Publications (1)

Publication Number Publication Date
DK2100959T3 true DK2100959T3 (da) 2017-01-30

Family

ID=25413278

Family Applications (2)

Application Number Title Priority Date Filing Date
DK09156327.0T DK2100959T3 (da) 1997-07-25 1998-07-24 Pattedyrscytokin: Interleukin-B30 og tilhørende reagenser
DK98937105T DK1002084T3 (da) 1997-07-25 1998-07-24 Mammalt cytokin: interleukin-B30 og beslægtede reagenser

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK98937105T DK1002084T3 (da) 1997-07-25 1998-07-24 Mammalt cytokin: interleukin-B30 og beslægtede reagenser

Country Status (28)

Country Link
EP (3) EP2100959B1 (da)
JP (5) JP4316133B2 (da)
KR (1) KR100666835B1 (da)
CN (2) CN101851286A (da)
AR (2) AR017510A1 (da)
AT (1) ATE443142T1 (da)
AU (1) AU741046B2 (da)
BR (1) BR9811039A (da)
CA (1) CA2296272C (da)
CO (1) CO4810232A1 (da)
CZ (1) CZ300958B6 (da)
DE (1) DE69841161D1 (da)
DK (2) DK2100959T3 (da)
ES (2) ES2331762T3 (da)
HU (1) HU230629B1 (da)
ID (1) ID28114A (da)
IL (3) IL134068A0 (da)
LT (1) LT2100959T (da)
MY (1) MY157028A (da)
NO (1) NO329329B1 (da)
NZ (1) NZ502391A (da)
PE (1) PE20000183A1 (da)
PL (1) PL197150B1 (da)
PT (2) PT2100959T (da)
SK (1) SK287198B6 (da)
TW (1) TWI237057B (da)
WO (1) WO1999005280A1 (da)
ZA (1) ZA986596B (da)

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ATE474849T1 (de) * 1998-04-14 2010-08-15 Chugai Pharmaceutical Co Ltd Neues cytokinartiges protein
EP1905832A3 (en) 1999-09-09 2009-09-09 Schering Corporation Mammalian interleukin-12 P40 and interleukin B30, combinations thereof, antibodies, uses in pharmaceutical compositions
US7090847B1 (en) 1999-09-09 2006-08-15 Schering Corporation Mammalian cytokines; related reagents and methods
AU2005202420B2 (en) * 1999-09-09 2008-08-07 Merck Sharp & Dohme Corp. Mammalian cytokines; related reagents and methods
DE60038304T3 (de) * 1999-09-09 2017-04-06 Merck Sharp & Dohme Corp. Interleukin-12 p40 und interleukin-b30. kombinationen davon. antikörper. verwendungen in pharmazeutische zusammensetzungen
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EP1623011B1 (en) 2003-05-09 2013-01-02 Janssen Biotech, Inc. Il-23p40 specific immunoglobulin derived proteins, compositions, methods and uses
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AR051444A1 (es) 2004-09-24 2007-01-17 Centocor Inc Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos
CA2613818C (en) 2005-06-30 2013-08-27 Centocor, Inc. Anti-il-23 antibodies, compositions, methods and uses
SI3219328T1 (sl) 2005-12-29 2020-10-30 Janssen Biotech, Inc. Človeška protitelesa proti-IL-23, sestavki, postopki in uporabe
US7910703B2 (en) 2006-03-10 2011-03-22 Zymogenetics, Inc. Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use
JP2009540018A (ja) 2006-06-13 2009-11-19 ザイモジェネティクス， インコーポレイテッド Ｉｌ−１７およびｉｌ−２３アンタゴニストならびにその使用方法
TWI426918B (zh) 2007-02-12 2014-02-21 Merck Sharp & Dohme Ｉｌ-２３拮抗劑於治療感染之用途
CA2706425A1 (en) 2007-11-27 2009-06-04 Ablynx N.V. Method for obtaining polypeptide constructs comprising two or more single domain antibodies
BRPI0908312A2 (pt) 2008-05-05 2015-08-18 Novimmune Sa '' anticorpo monoclonal totalmente humano isolado, composição farmacêutica, método de alívio de um sintoma de uma indicação clínica e método de alívio de um sintoma de uma doença autoimune, distúrbio inflamatório ou distúrbio da proliferação celular''
EP2427203B1 (en) 2009-05-05 2018-10-17 Novimmune S.A. Anti-il-17f antibodies and use thereof
JO3244B1 (ar) 2009-10-26 2018-03-08 Amgen Inc بروتينات ربط مستضادات il – 23 البشرية
KR102049223B1 (ko) 2010-11-04 2019-11-28 베링거 인겔하임 인터내셔날 게엠베하 항－ｉｌ－２３ 항체
CN109206516A (zh) 2012-05-03 2019-01-15 勃林格殷格翰国际有限公司 抗IL-23p19抗体
EP3689369A1 (en) 2013-03-15 2020-08-05 Amgen, Inc Methods for treating psoriasis using an anti-il-23 antibody
US20160031983A1 (en) 2013-03-15 2016-02-04 Amgen Inc. Methods for treating crohn's disease using an anti-il23 antibody
EP3172339A1 (en) 2014-07-24 2017-05-31 Boehringer Ingelheim International GmbH Biomarkers useful in the treatment of il-23a related diseases
CA2959629C (en) 2014-09-03 2023-10-31 Boehringer Ingelheim International Gmbh Compound targeting il-23a and tnf-alpha and uses thereof
KR20170120616A (ko) 2015-02-04 2017-10-31 베링거 인겔하임 인터내셔날 게엠베하 염증성 질환의 치료 방법
MX2018003376A (es) 2015-09-17 2018-08-15 Amgen Inc Prediccion de la respuesta clinica a antagonistas de il23 mediante el uso de biomarcadores de la via de il23.
WO2017112536A1 (en) 2015-12-22 2017-06-29 Amgen Inc. Ccl20 as a predictor of clinical response to il23-antagonists
JP2021532176A (ja) 2018-07-13 2021-11-25 アストラゼネカ・コラボレイション・ベンチャーズ・リミテッド・ライアビリティ・カンパニーAstrazeneca Collaboration Ventures, Llc ブラジクマブによる潰瘍性大腸炎の処置
MA55149A (fr) 2018-11-20 2021-09-29 Janssen Biotech Inc Procédé sûr et efficace de traitement du psoriasis avec un anticorps spécifique anti-il-23
EP3972690A4 (en) 2019-05-23 2023-07-05 Janssen Biotech, Inc. METHOD OF TREATMENT OF INFLAMMATORY BOWEL DISEASE USING COMBINATION THERAPY OF ANTIBODIES TO IL-23 AND TNF-ALPHA
TW202535466A (zh) 2019-09-09 2025-09-16 德商百靈佳殷格翰國際股份有限公司 抗-il-23p19抗體調配物
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Also Published As

Publication number Publication date
NO20000343L (no) 2000-03-24
SK287198B6 (sk) 2010-03-08
IL134068A (en) 2010-11-30
JP2005323610A (ja) 2005-11-24
AU741046B2 (en) 2001-11-22
KR20010022214A (ko) 2001-03-15
NO20000343D0 (no) 2000-01-24
WO1999005280A1 (en) 1999-02-04
BR9811039A (pt) 2000-08-08
IL205765A0 (en) 2011-07-31
EP2100959B1 (en) 2016-12-07
NZ502391A (en) 2002-12-20
CO4810232A1 (es) 1999-06-30
KR100666835B1 (ko) 2007-01-11
JP2015037405A (ja) 2015-02-26
DE69841161D1 (de) 2009-10-29
ES2610483T3 (es) 2017-04-27
AR017510A1 (es) 2001-09-12
JP2001511347A (ja) 2001-08-14
ES2331762T3 (es) 2010-01-14
LT2100959T (lt) 2017-01-10
NO329329B1 (no) 2010-09-27
AU8589498A (en) 1999-02-16
JP2010011863A (ja) 2010-01-21
HU230629B1 (hu) 2017-04-28
HK1024932A1 (en) 2000-10-27
HUP0004019A2 (en) 2001-03-28
PL338262A1 (en) 2000-10-09
ZA986596B (en) 1999-02-08
EP2100959A3 (en) 2009-10-14
CZ2000263A3 (cs) 2000-06-14
EP1002084A1 (en) 2000-05-24
CN101851286A (zh) 2010-10-06
IL134068A0 (en) 2001-04-30
AR086483A2 (es) 2013-12-18
TWI237057B (en) 2005-08-01
HUP0004019A3 (en) 2003-08-28
JP2013034480A (ja) 2013-02-21
ID28114A (id) 2001-05-03
SK912000A3 (en) 2000-09-12
PL197150B1 (pl) 2008-03-31
DK1002084T3 (da) 2010-01-04
CN1271387A (zh) 2000-10-25
EP1002084B1 (en) 2009-09-16
EP2233574A1 (en) 2010-09-29
IL205765A (en) 2015-07-30
MY157028A (en) 2016-04-15
CA2296272A1 (en) 1999-02-04
PE20000183A1 (es) 2000-03-11
JP4316133B2 (ja) 2009-08-19
CZ300958B6 (cs) 2009-09-23
PT1002084E (pt) 2009-12-16
EP2100959A2 (en) 2009-09-16
CA2296272C (en) 2012-03-13
PT2100959T (pt) 2017-01-09
ATE443142T1 (de) 2009-10-15

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