DK2105497T3 - Progenitorcellepopulationer, ekspansion heraf samt vækst af ikke-hæmatopoietiske celletyper og væv fra disse - Google Patents

Progenitorcellepopulationer, ekspansion heraf samt vækst af ikke-hæmatopoietiske celletyper og væv fra disse Download PDF

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Publication number
DK2105497T3
DK2105497T3 DK09007601.9T DK09007601T DK2105497T3 DK 2105497 T3 DK2105497 T3 DK 2105497T3 DK 09007601 T DK09007601 T DK 09007601T DK 2105497 T3 DK2105497 T3 DK 2105497T3
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Denmark
Prior art keywords
expansion
growth
cell types
hematopoietic cell
cell populations
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DK09007601.9T
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English (en)
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Dolores Baksh
John E Davies
Peter Zandstra
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Dolores Baksh
John E Davies
Peter Zandstra
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Application filed by Dolores Baksh, John E Davies, Peter Zandstra filed Critical Dolores Baksh
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Publication of DK2105497T3 publication Critical patent/DK2105497T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
DK09007601.9T 2001-04-24 2002-04-23 Progenitorcellepopulationer, ekspansion heraf samt vækst af ikke-hæmatopoietiske celletyper og væv fra disse DK2105497T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28570101P 2001-04-24 2001-04-24
US32811001P 2001-10-11 2001-10-11
EP02719587A EP1383869B1 (en) 2001-04-24 2002-04-23 Progenitor cell populations, expansion thereof, and growth of non-hematopoietic cell types and tissues therefrom

Publications (1)

Publication Number Publication Date
DK2105497T3 true DK2105497T3 (da) 2019-06-24

Family

ID=26963332

Family Applications (2)

Application Number Title Priority Date Filing Date
DK09007601.9T DK2105497T3 (da) 2001-04-24 2002-04-23 Progenitorcellepopulationer, ekspansion heraf samt vækst af ikke-hæmatopoietiske celletyper og væv fra disse
DK02719587T DK1383869T3 (da) 2001-04-24 2002-04-23 Stamcelle populationer, opformering heraf, og vækst af ikke-hæmatopoietiske celletyper og væv herfra

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK02719587T DK1383869T3 (da) 2001-04-24 2002-04-23 Stamcelle populationer, opformering heraf, og vækst af ikke-hæmatopoietiske celletyper og væv herfra

Country Status (9)

Country Link
US (2) US20040137612A1 (da)
EP (2) EP1383869B1 (da)
JP (1) JP2004531256A (da)
AT (1) ATE433484T1 (da)
CA (2) CA2843001A1 (da)
DE (1) DE60232585D1 (da)
DK (2) DK2105497T3 (da)
ES (1) ES2328460T3 (da)
WO (1) WO2002086104A1 (da)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1383869B1 (en) 2001-04-24 2009-06-10 Dolores Baksh Progenitor cell populations, expansion thereof, and growth of non-hematopoietic cell types and tissues therefrom
WO2004069172A2 (en) 2003-01-30 2004-08-19 The Government of the United States of America as represented by the Department of Veterans Affairs Multilineage-inducible cells and uses thereof
WO2004072273A1 (en) 2003-02-11 2004-08-26 Davies John E Progenitor cells from wharton's jelly of human umbilical cord
CN100377165C (zh) * 2003-04-24 2008-03-26 皇家飞利浦电子股份有限公司 无创式左心室的容积测定
JP4604238B2 (ja) * 2003-09-19 2011-01-05 独立行政法人産業技術総合研究所 燐酸カルシウムと生理活性物質を含有する高分子複合体、その製造方法及びそれを用いた医療用材料
WO2005085428A1 (en) 2004-03-05 2005-09-15 Davies John E Serum-free suspension culture system for mesenchymal progenitor cells
US7670596B2 (en) * 2004-04-23 2010-03-02 Bioe, Inc. Multi-lineage progenitor cells
US7622108B2 (en) * 2004-04-23 2009-11-24 Bioe, Inc. Multi-lineage progenitor cells
PL1874821T3 (pl) 2005-04-26 2013-09-30 Trion Pharma Gmbh Kombinacja przeciwciał i glikokortykoidów do leczenia raka
WO2007022348A2 (en) * 2005-08-18 2007-02-22 Massachusetts Institute Of Technology Amplification of cell polulations from embryonic stem cells
EP1962719A4 (en) 2005-08-29 2011-05-04 Technion Res And Dev Of Foundation Ltd MEDIA FOR BREEDING STEM CELLS
CN103173401A (zh) 2005-12-22 2013-06-26 简·恩尼斯 来自冷冻的脐带组织的活细胞
ITTO20060282A1 (it) * 2006-04-14 2007-10-15 Univ Degli Studi Torino Mezzo di coltura e composizione farmaceutica per la rigenerazione del tessuto cartilagineo relativo procedimento relativi usi e prodotti
CA2646491A1 (en) * 2006-04-17 2007-10-25 Bioe, Inc. Differentiation of multi-lineage progenitor cells to respiratory epithelial cells
CA2649874C (en) 2006-05-05 2015-01-27 John E. Davies Immune privileged and modulatory progenitor cells
WO2008006168A1 (en) * 2006-07-12 2008-01-17 Angioblast Systems, Inc. Treatment of excessive neovascularization
DK3441459T3 (da) * 2006-08-02 2021-06-07 Technion Res & Dev Foundation Fremgangsmåder til ekspansion af embryonale stamceller i en suspensionskultur
CA2693827A1 (en) * 2007-07-25 2009-01-29 Bioe, Inc. Differentiation of multi-lineage progenitor cells to chondrocytes
CA2718174A1 (en) * 2008-03-03 2009-09-11 William Marsh Rice University Methods of fabricating enhanced tissue-engineered cartilage
BRPI0910686A2 (pt) 2008-04-21 2015-09-29 Tissue Regeneration Therapeutics Inc células perivasculares do cordão umbilical humano geneticamente modificadas para a profilaxia contra agentes biológicos e químicos ou para o tratamento dos mesmos.
WO2009139419A1 (ja) * 2008-05-14 2009-11-19 公立大学法人横浜市立大学 ヒト肝幹細胞、その調製方法、分化誘導方法及び利用方法
CA2724839A1 (en) * 2008-05-21 2009-11-26 Bioe Llc Differentiation of multi-lineage progenitor cells to pancreatic cells
SG185526A1 (en) 2010-05-12 2012-12-28 Abt Holding Co Modulation of splenocytes in cell therapy
WO2012046065A2 (en) 2010-10-06 2012-04-12 Omnicyte Limited Culture method
WO2012048276A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
IL289870B2 (en) 2013-04-12 2023-03-01 Lafrancesca Saverio Improving organs for transplantation
WO2015073913A1 (en) 2013-11-16 2015-05-21 Terumo Bct, Inc. Expanding cells in a bioreactor
WO2015148704A1 (en) 2014-03-25 2015-10-01 Terumo Bct, Inc. Passive replacement of media
EP3198006B1 (en) 2014-09-26 2021-03-24 Terumo BCT, Inc. Scheduled feed
WO2016111966A1 (en) * 2015-01-05 2016-07-14 Histogenics Corporation Neocartilage constructs using universal cells
EP3098304A1 (en) 2015-05-28 2016-11-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Hybrid cell detachment-free cell expansion system for adherent cell culturing and related proceeding protocol
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
NZ745530A (en) 2016-01-21 2023-03-31 Abt Holding Co Stem cells for wound healing
KR102557574B1 (ko) * 2016-05-17 2023-07-20 엘지전자 주식회사 디지털 디바이스 및 그 제어 방법
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
CN117247899A (zh) 2017-03-31 2023-12-19 泰尔茂比司特公司 细胞扩增
US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
WO2020061408A1 (en) * 2018-09-21 2020-03-26 Tarachon Llc Cartilage regeneration by synovial fluid-derived stem cells and their derivatives
EP4314244B1 (en) 2021-03-23 2025-07-23 Terumo BCT, Inc. Cell capture and expansion
US12209689B2 (en) 2022-02-28 2025-01-28 Terumo Kabushiki Kaisha Multiple-tube pinch valve assembly
USD1099116S1 (en) 2022-09-01 2025-10-21 Terumo Bct, Inc. Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3850748A (en) * 1973-06-28 1974-11-26 Lilly Co Eli Method of producing animal cells in suspension culture
US4495288A (en) 1981-03-13 1985-01-22 Damon Biotech, Inc. Method of culturing anchorage dependent cells
US5763266A (en) * 1989-06-15 1998-06-09 The Regents Of The University Of Michigan Methods, compositions and devices for maintaining and growing human stem and/or hematopoietics cells
US6010696A (en) * 1990-11-16 2000-01-04 Osiris Therapeutics, Inc. Enhancing hematopoietic progenitor cell engraftment using mesenchymal stem cells
US5226914A (en) * 1990-11-16 1993-07-13 Caplan Arnold I Method for treating connective tissue disorders
US5486359A (en) * 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5837539A (en) * 1990-11-16 1998-11-17 Osiris Therapeutics, Inc. Monoclonal antibodies for human mesenchymal stem cells
US5197985A (en) * 1990-11-16 1993-03-30 Caplan Arnold I Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells
US5736396A (en) * 1995-01-24 1998-04-07 Case Western Reserve University Lineage-directed induction of human mesenchymal stem cell differentiation
US5855610A (en) 1995-05-19 1999-01-05 Children's Medical Center Corporation Engineering of strong, pliable tissues
US7514074B2 (en) * 1997-07-14 2009-04-07 Osiris Therapeutics, Inc. Cardiac muscle regeneration using mesenchymal stem cells
AU3112499A (en) * 1998-03-23 1999-10-18 Zymogenetics Inc. Cardiac-derived stem cells
CA2348687A1 (en) 1998-11-09 2000-05-18 Consorzio Per La Gestione Del Centro Di Biotecnologie Avanzate Serum free medium for chondrocyte-like cells
WO2001011011A2 (en) * 1999-08-05 2001-02-15 Mcl Llc Multipotent adult stem cells and methods for isolation
EP1383869B1 (en) 2001-04-24 2009-06-10 Dolores Baksh Progenitor cell populations, expansion thereof, and growth of non-hematopoietic cell types and tissues therefrom
KR100534215B1 (ko) 2003-11-11 2005-12-08 (주)히스토스템 냉동 보관된 제대혈로부터 중간엽 줄기세포의 분리 및 배양 방법

Also Published As

Publication number Publication date
WO2002086104A1 (en) 2002-10-31
EP1383869A1 (en) 2004-01-28
CA2444959C (en) 2014-07-08
US9644182B2 (en) 2017-05-09
ES2328460T3 (es) 2009-11-13
US20040137612A1 (en) 2004-07-15
ATE433484T1 (de) 2009-06-15
EP2105497A1 (en) 2009-09-30
US20080020459A1 (en) 2008-01-24
CA2843001A1 (en) 2002-10-31
DK1383869T3 (da) 2009-10-05
DE60232585D1 (de) 2009-07-23
EP1383869B1 (en) 2009-06-10
JP2004531256A (ja) 2004-10-14
CA2444959A1 (en) 2002-10-31
EP2105497B1 (en) 2019-04-03

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