DK212185A - Triphenylmetyl-derivater af glycero-3-phosphocholin og glycero-3-phosphoethanolamin og fremgangsmaade til fremstilling heraf - Google Patents

Triphenylmetyl-derivater af glycero-3-phosphocholin og glycero-3-phosphoethanolamin og fremgangsmaade til fremstilling heraf Download PDF

Info

Publication number: DK212185A
Authority: DK; Denmark
Prior art keywords: glycero; phosphoethanolamine; phosphocholine; procedures; preparing
Prior art date: 1984-05-15

Application number

DK212185A

Other languages

English (en)

Other versions

DK167441B (da

DK212185D0 (da

DK167441C (da

Inventor

Friederich Paltauf

Albin Hermetter

Original Assignee

Chemie Linz Aktiengeselschaft

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-05-15

Filing date

1985-05-14

Publication date

1985-11-16

1985-05-14 Application filed by Chemie Linz Aktiengeselschaft filed Critical Chemie Linz Aktiengeselschaft

1985-05-14 Publication of DK212185D0 publication Critical patent/DK212185D0/da

1985-11-16 Publication of DK212185A publication Critical patent/DK212185A/da

1993-11-01 Publication of DK167441B publication Critical patent/DK167441B/da

1994-04-18 Application granted granted Critical

1994-04-18 Publication of DK167441C publication Critical patent/DK167441C/da

Links

-1 TRIPHENYLMETHYL DERIVATIVES OF GLYCERO-3-PHOSPHOCHOLINE Chemical class 0.000 title 1
238000000034 method Methods 0.000 title 1
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
230000010933 acylation Effects 0.000 abstract 1
238000005917 acylation reaction Methods 0.000 abstract 1
JZNWSCPGTDBMEW-YFKPBYRVSA-N sn-glycero-3-phosphoethanolamine Chemical compound NCCO[P@@](O)(=O)OC[C@@H](O)CO JZNWSCPGTDBMEW-YFKPBYRVSA-N 0.000 abstract 1
125000002221 trityl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C([*])(C1=C(C(=C(C(=C1[H])[H])[H])[H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Hydrogenated Pyridines (AREA)
Epoxy Resins (AREA)

DK212185A 1984-05-15 1985-05-14 Fremgangsmaade til fremstilling af blandet substituerede, enantiomer-rene 1,2-diacyl-sn-glycero-3-phosphocholiner og 1,2-diacyl-sn-glycero-3-phosphoethanolaminer DK167441C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
AT159084		1984-05-15
AT0159084A AT383130B (de)	1984-05-15	1984-05-15	Verfahren zur herstellung von an c1 und c2 verschieden substituierten phosphatidylcholinen und phosphatidylethanolaminen ueber die neuen verbindungen 1-0-tritylglycerophosphocholin beziehungsweise (1-0,n-ditrityl)-glycerophosphoethanolamin

Publications (4)

Publication Number	Publication Date
DK212185D0 DK212185D0 (da)	1985-05-14
DK212185A true DK212185A (da)	1985-11-16
DK167441B DK167441B (da)	1993-11-01
DK167441C DK167441C (da)	1994-04-18

Family

ID=3516711

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK212185A DK167441C (da)	1984-05-15	1985-05-14	Fremgangsmaade til fremstilling af blandet substituerede, enantiomer-rene 1,2-diacyl-sn-glycero-3-phosphocholiner og 1,2-diacyl-sn-glycero-3-phosphoethanolaminer
DK92981A DK98192D0 (da)	1984-05-15	1992-08-03	Triphenylmethyl-derivater af sn-glycero-3-phosphocholin og sn-glycero-3-phosphoethanolamin og fremgangsmaade til fremstilling deraf

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK92981A DK98192D0 (da)	1984-05-15	1992-08-03	Triphenylmethyl-derivater af sn-glycero-3-phosphocholin og sn-glycero-3-phosphoethanolamin og fremgangsmaade til fremstilling deraf

Country Status (24)

Country	Link
US (2)	US4622180A (da)
EP (1)	EP0161519B1 (da)
JP (1)	JPS60252490A (da)
KR (1)	KR920009556B1 (da)
CN (1)	CN1014791B (da)
AT (2)	AT383130B (da)
AU (1)	AU565316B2 (da)
BR (1)	BR8502293A (da)
CA (1)	CA1244462A (da)
DD (2)	DD245668A1 (da)
DE (1)	DE3563533D1 (da)
DK (2)	DK167441C (da)
ES (2)	ES543146A0 (da)
FI (1)	FI77663C (da)
HU (2)	HU199486B (da)
IE (1)	IE58511B1 (da)
IL (1)	IL75133A (da)
NO (1)	NO163100C (da)
NZ (1)	NZ212067A (da)
PH (2)	PH21831A (da)
SU (2)	SU1422999A3 (da)
TR (1)	TR22204A (da)
YU (2)	YU45719B (da)
ZA (1)	ZA853697B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AT383130B (de) *	1984-05-15	1987-05-25	Chemie Linz Ag	Verfahren zur herstellung von an c1 und c2 verschieden substituierten phosphatidylcholinen und phosphatidylethanolaminen ueber die neuen verbindungen 1-0-tritylglycerophosphocholin beziehungsweise (1-0,n-ditrityl)-glycerophosphoethanolamin
DE3638687A1 (de) *	1986-11-13	1988-05-19	Lentia Gmbh	Einstufiges verfahren zur herstellung von gemischt substituierten 1,2-di-acyl-sn-glycero-3-phosphocholinen
AT388165B (de) *	1986-12-10	1989-05-10	Chemie Linz Ag	Einstufiges verfahren zur herstellung von gemischt substituierten 1,2-di-acyl-sn-glycero-3- phosphocholinen
JP2657486B2 (ja) *	1987-02-20	1997-09-24	花王株式会社	洗浄剤組成物
US5144045A (en) *	1990-11-13	1992-09-01	American Cyanamid Company	Phosphocholine derivative inhibitors of phospholipase A2
DE4233044A1 (de) *	1992-10-01	1994-04-07	Asta Medica Ag	Phospholipidderivate, die höhere Elemente der V. Hauptgruppe enthalten
US5698537A (en) *	1996-06-18	1997-12-16	Clarion Pharmaceuticals Inc.	Method of lowering the viscosity of mucus
US6838452B2 (en) *	2000-11-24	2005-01-04	Vascular Biogenics Ltd.	Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis
EP2324828A1 (en) *	2003-08-18	2011-05-25	BTG International Limited	Treatment for neurodegenerative conditions
US7807847B2 (en)	2004-07-09	2010-10-05	Vascular Biogenics Ltd.	Process for the preparation of oxidized phospholipids
NZ553147A (en) *	2004-07-09	2010-07-30	Vascular Biogenics Ltd	Improved process for the preparation of oxidized phospholipids
GB0425932D0 (en) *	2004-11-25	2004-12-29	Btg Int Ltd	Structured phospholipids
GB0504362D0 (en)	2005-03-02	2005-04-06	Btg Int Ltd	Cytokine modulators
US8569529B2 (en)	2007-01-09	2013-10-29	Vascular Biogenics Ltd.	High-purity phospholipids
US9006217B2 (en)	2007-01-09	2015-04-14	Vascular Biogenics Ltd.	High-purity phospholipids
RU2382765C1 (ru) *	2008-10-24	2010-02-27	Государственное образовательное учреждение высшего профессионального образования "Московская государственная академия тонкой химической технологии имени М.В. Ломоносова"	Rac-N,N-ДИМЕТИЛ-N-[2-(5-N',N'- ДИМЕТИЛАМИНОНАФТАЛЕН-1-СУЛЬФОНИЛОКСИ)ЭТИЛ]-N- {4-[(2-МЕТОКСИ-3-ОКТАДЕЦИЛОКСИ)ПРОП-1-ИЛОКСИКАРБОНИЛ]БУТИЛ} АММОНИЙИОДИД
KR20110095288A (ko) *	2008-11-06	2011-08-24	바스큘라 바이오제닉스 리미티드	산화된 지질 화합물 및 이의 용도
CN104017019A (zh) *	2014-06-12	2014-09-03	东南大学	一种氮芥-甘油磷脂酰胆碱化合物的合成方法
CN106999506A (zh)	2014-11-26	2017-08-01	脉管生物生长有限公司	氧化脂质以及纤维化的治疗或预防
US9771385B2 (en)	2014-11-26	2017-09-26	Vascular Biogenics Ltd.	Oxidized lipids
CZ308596B6 (cs) *	2017-04-03	2020-12-23	Ústav molekulární genetiky AV ČR, v. v. i.	Deriváty fosfolipidů a jejich použití jako léčiva
PL232298B1 (pl) *	2017-06-30	2019-06-28	Univ Przyrodniczy We Wroclawiu	Sposób otrzymywania fosfatydylocholiny zawierającej ibuprofen w pozycji sn-1
PL232663B1 (pl) *	2017-06-30	2019-07-31	Univ Przyrodniczy We Wroclawiu	Fosfatydylocholiny oraz sposób ich otrzymywania

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2820893C2 (de) *	1978-05-12	1986-02-20	A. Nattermann & Cie GmbH, 5000 Köln	Strukturanaloga von natürlichen Phospholipiden und Verfahren zur Herstellung dieser Verbindungen
IT1123187B (it) *	1979-09-17	1986-04-30	Lpb Ist Farm	Processo per la preparazione di l-alfa-glicerilfosforilcolina
DE3130867A1 (de) *	1981-08-04	1983-02-24	Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen	Zwischenprodukte zur herstellung von glycerinderivaten
AT383130B (de) *	1984-05-15	1987-05-25	Chemie Linz Ag	Verfahren zur herstellung von an c1 und c2 verschieden substituierten phosphatidylcholinen und phosphatidylethanolaminen ueber die neuen verbindungen 1-0-tritylglycerophosphocholin beziehungsweise (1-0,n-ditrityl)-glycerophosphoethanolamin

1984
- 1984-05-15 AT AT0159084A patent/AT383130B/de not_active IP Right Cessation
1985
- 1985-04-19 AT AT85104662T patent/ATE35416T1/de not_active IP Right Cessation
- 1985-04-19 EP EP85104662A patent/EP0161519B1/de not_active Expired
- 1985-04-19 DE DE8585104662T patent/DE3563533D1/de not_active Expired
- 1985-05-07 IE IE113685A patent/IE58511B1/en not_active IP Right Cessation
- 1985-05-07 FI FI851781A patent/FI77663C/fi not_active IP Right Cessation
- 1985-05-08 IL IL75133A patent/IL75133A/xx unknown
- 1985-05-09 CA CA000481204A patent/CA1244462A/en not_active Expired
- 1985-05-13 US US06/733,619 patent/US4622180A/en not_active Expired - Lifetime
- 1985-05-13 PH PH32256A patent/PH21831A/en unknown
- 1985-05-14 ES ES543146A patent/ES543146A0/es active Granted
- 1985-05-14 NZ NZ212067A patent/NZ212067A/xx unknown
- 1985-05-14 HU HU851813A patent/HU199486B/hu not_active IP Right Cessation
- 1985-05-14 NO NO851928A patent/NO163100C/no unknown
- 1985-05-14 DK DK212185A patent/DK167441C/da not_active IP Right Cessation
- 1985-05-14 SU SU853898601A patent/SU1422999A3/ru active
- 1985-05-14 SU SU853896546A patent/SU1400511A3/ru active
- 1985-05-14 AU AU42448/85A patent/AU565316B2/en not_active Ceased
- 1985-05-14 HU HU895132A patent/HU203555B/hu not_active IP Right Cessation
- 1985-05-14 KR KR1019850003277A patent/KR920009556B1/ko not_active Expired
- 1985-05-14 DD DD85276325A patent/DD245668A1/de not_active IP Right Cessation
- 1985-05-14 ES ES543147A patent/ES8603900A1/es not_active Expired
- 1985-05-14 DD DD85276324A patent/DD233130A1/de not_active IP Right Cessation
- 1985-05-15 BR BR8502293A patent/BR8502293A/pt not_active IP Right Cessation
- 1985-05-15 YU YU81585A patent/YU45719B/sh unknown
- 1985-05-15 TR TR22204A patent/TR22204A/xx unknown
- 1985-05-15 YU YU81685A patent/YU45720B/sh unknown
- 1985-05-15 ZA ZA853697A patent/ZA853697B/xx unknown
- 1985-05-15 JP JP60101644A patent/JPS60252490A/ja active Granted
- 1985-06-11 CN CN85104463A patent/CN1014791B/zh not_active Expired
1986
- 1986-07-29 US US06/891,515 patent/US4717512A/en not_active Expired - Lifetime
1987
- 1987-07-06 PH PH35499A patent/PH23978A/en unknown
1992
- 1992-08-03 DK DK92981A patent/DK98192D0/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
CN1014791B (zh)	1991-11-20
SU1400511A3 (ru)	1988-05-30
YU81685A (en)	1987-10-31
DK98192A (da)	1992-08-03
DK167441B (da)	1993-11-01
BR8502293A (pt)	1986-01-21
ZA853697B (en)	1986-01-29
FI851781L (fi)	1985-11-16
SU1422999A3 (ru)	1988-09-07
PH23978A (en)	1990-02-09
HUT39454A (en)	1986-09-29
US4622180A (en)	1986-11-11
ES8603899A1 (es)	1986-01-01
EP0161519B1 (de)	1988-06-29
ATE35416T1 (de)	1988-07-15
KR920009556B1 (ko)	1992-10-19
AT383130B (de)	1987-05-25
FI851781A0 (fi)	1985-05-07
IL75133A (en)	1988-12-30
FI77663B (fi)	1988-12-30
DK212185D0 (da)	1985-05-14
IE58511B1 (en)	1993-10-06
AU565316B2 (en)	1987-09-10
YU81585A (en)	1987-10-31
AU4244885A (en)	1985-11-21
EP0161519A2 (de)	1985-11-21
CA1244462A (en)	1988-11-08
NO851928L (no)	1985-11-18
HU199486B (en)	1990-02-28
ES543147A0 (es)	1986-01-01
IE851136L (en)	1985-11-15
YU45720B (sh)	1992-07-20
TR22204A (tr)	1986-09-24
DK167441C (da)	1994-04-18
PH21831A (en)	1988-03-17
JPS60252490A (ja)	1985-12-13
JPH0482157B2 (da)	1992-12-25
NO163100C (no)	1990-04-04
YU45719B (sh)	1992-07-20
EP0161519A3 (en)	1986-02-12
NZ212067A (en)	1988-10-28
KR850008677A (ko)	1985-12-21
DE3563533D1 (en)	1988-08-04
NO163100B (no)	1989-12-27
CN85104463A (zh)	1986-12-10
US4717512A (en)	1988-01-05
DD233130A1 (de)	1986-02-19
FI77663C (fi)	1989-04-10
CA1251462C (da)	1989-03-21
DD245668A1 (de)	1987-05-13
HU203555B (en)	1991-08-28
ES8603900A1 (es)	1986-01-01
ATA159084A (de)	1986-10-15
ES543146A0 (es)	1986-01-01
IL75133A0 (en)	1985-09-29
DK98192D0 (da)	1992-08-03

Legal Events

Date	Code	Title	Description
1990-07-23	AHS	Application shelved for other reasons than non-payment
1996-01-22	PBP	Patent lapsed

Publication	Publication Date	Title
DK212185D0 (da)	1985-05-14	Triphenylmetyl-derivater af glycero-3-phosphocholin og glycero-3-phosphoethanolamin og fremgangsmaade til fremstilling heraf
ES555602A0 (es)	1987-07-01	Procedimiento para la obtencion de 3-amino-1-hidroxi-propan-1,1-difosfonato disordico
ES552397A0 (es)	1987-05-01	Procedimiento para la obtencion de poli-hidro piridazo diacepinas, triacepinas o diazocinas
DK210483D0 (da)	1983-05-11	Pyrogallolderivater, deres anvendelse og fremgangsmade til fremstilling deraf
IT8120231A0 (it)	1981-03-09	Procedimento per la produzione di enzima fruttosil transferasi.
IT8422245A0 (it)	1984-08-07	Procedimento per la preparazione di derivati del lisergolo.
DK403782A (da)	1983-03-11	9,10-substituerede 2-mesitylimino-3-alkyl-3,4,6,7-tetrahydro-2h-pyrimido(6,1-a)isoquinolin-4-oner, fremgangsmaade til deres fremstilling og deres anvendelse som laegemidler
IT8522385A0 (it)	1985-10-08	Procedimento per la preparazione di derivati della motomicina cn7-sostituiti.
IT8321507A0 (it)	1983-06-07	Procedimento di preparazione fermentativa di l-leucina.
ES507729A0 (es)	1982-09-01	Procedimiento para la obtencion de 6(9)-isopropil-9(6)-metil-6,9 etano-2-oxaspiro n4,5n-dec-7-enos de efecto perfumante.
FI851969A7 (fi)	1985-11-18	Korkean verenpaineen hoitoon soveltuvia tetrahydronaftalenoleja.
IT8219589A0 (it)	1982-02-10	Procedimento per la preparazione di sclareolo.
DK581086A (da)	1988-06-04	Fremgangsmaade til fremstilling af alkyltrifluoracetater
IT8322540A0 (it)	1983-08-12	Procedimento per la preparazione di derivati della 2,4-diammino-5-benzil-pirimidina.
IT8222398A0 (it)	1982-07-14	Procedimento per la preparazione di derivati della 1,5-benzotiazepina.
AR226096A1 (es)	1982-05-31	Procedimiento para la preparacion de n,n-dimetil-10-(1-aza(2,2,2)-biciclo-3-octil)10h-2-fenotiazinsulfonamida
ES552400A0 (es)	1987-05-01	Procedimiento para la obtencion de poli-hidro piridazo diacepinas, triacepinas o diazocinas
DK165641C (da)	1993-06-01	Fremgangsmaade til fremstilling af tf-220, tf-230 og tf-240 forbindelser og de tilsvarende proteinfrie forbindelser
IT8125879A0 (it)	1981-12-29	Procedimento per la preparazione della pantetina.
IT8420686A0 (it)	1984-04-24	Procedimenti per la preparazione di derivati delbis-idrossietilmercapto-1,10-decano.